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The map label for this gene is ycbL [C]

Identifier: 146339205

GI number: 146339205

Start: 2302341

End: 2303213

Strand: Direct

Name: ycbL [C]

Synonym: BRADO2167

Alternate gene names: 146339205

Gene position: 2302341-2303213 (Clockwise)

Preceding gene: 146339197

Following gene: 146339210

Centisome position: 30.88

GC content: 64.6

Gene sequence:

>873_bases
TTGCTCGCCGCCACGCTGGCTTGGACGGCCGGTCCCGCTGCAGCGCAATCGCTGCCGGACTTCATGAAGCAGGTGATCGC
CACCTGGAACACGCCCACCGAGCCGTTCAAGGTGATCGACAACATCTATTACGTCGGCACCAACGGCCTGGCGTCCTACC
TGATCACCACGCCGCAGGGCCACATCCTGATCGACACGGTGATGCCGGAATCGACAGCGCTGATCGAGACCAGCATCGGC
AAGCTCGGCTTCAAGGTCGCCGACATCAAATACGTTATCAACACCCACGCTCATATCGATCACACCGGGGGACTCGCGCA
GATCAAGCAGGAGACCGGCGCGCAGATGGTGGCCGGCGCCAAGGACGTGCCGCTGCTCGAAGGCGGCTTCTATCCGGGCC
GCGAGGAGGAACGCTATCTGAATTTCCCGCCGGTCAAGGTCGACCGCGCCGTGCGCGAGGGCGACACAGTCACGCTCGGC
GGCGTCACCCTGACCGCGCATGAGACGCCCGGTCATTCGCCGGGCTGCACCAGCTGGACCACCGAGGTGAAGGACGGCGA
CGCGACGCGCAGCGTGATCTTTTTCTGCAGTGCCACCGTGGCGCTGAATCAGCTCGTGGGCCGGCCGACCTATCCGGGCA
TCGTCGACGACTACAAGAAGACCTATGCATGGGCGAAGACGGTGCATCCCGACGTGCTGCTGGCGCCGCATCCGGAGATG
TATGGCATGGCCGACAAGCGCGCCAAGATCGCCGACGGCGCGCCGAACCCGTTCGTGAAGCCGGGCGAGTTCAACGCCTA
TCTCGACAAGCTCGAGGCGCAGTTCAACGAAGGGCTCGCCAAGCAGACCGCCGCGCTGCAGTCCGGCAAGTAG

Upstream 100 bases:

>100_bases
AGCGGAGGACGTACGATTGCTTCGTCGCGATCGCGATGACATAAGACAAATTCATAACAACAATACCGGGAATGGGGAGG
TCGTGATGAAAAGAATGTTG

Downstream 100 bases:

>100_bases
CCATCACAAGGCGCCGAGCCGGTCCAGCGTGAAGCCGGAGAGATCGACCCGAGGCGTGGCCCCCAGCGCCATCGCCGCGA
GCGCCTCGCCTACGGCCGGC

Product: putative beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase type II; Penicillinase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLAATLAWTAGPAAAQSLPDFMKQVIATWNTPTEPFKVIDNIYYVGTNGLASYLITTPQGHILIDTVMPESTALIETSIG
KLGFKVADIKYVINTHAHIDHTGGLAQIKQETGAQMVAGAKDVPLLEGGFYPGREEERYLNFPPVKVDRAVREGDTVTLG
GVTLTAHETPGHSPGCTSWTTEVKDGDATRSVIFFCSATVALNQLVGRPTYPGIVDDYKKTYAWAKTVHPDVLLAPHPEM
YGMADKRAKIADGAPNPFVKPGEFNAYLDKLEAQFNEGLAKQTAALQSGK

Sequences:

>Translated_290_residues
MLAATLAWTAGPAAAQSLPDFMKQVIATWNTPTEPFKVIDNIYYVGTNGLASYLITTPQGHILIDTVMPESTALIETSIG
KLGFKVADIKYVINTHAHIDHTGGLAQIKQETGAQMVAGAKDVPLLEGGFYPGREEERYLNFPPVKVDRAVREGDTVTLG
GVTLTAHETPGHSPGCTSWTTEVKDGDATRSVIFFCSATVALNQLVGRPTYPGIVDDYKKTYAWAKTVHPDVLLAPHPEM
YGMADKRAKIADGAPNPFVKPGEFNAYLDKLEAQFNEGLAKQTAALQSGK
>Mature_290_residues
MLAATLAWTAGPAAAQSLPDFMKQVIATWNTPTEPFKVIDNIYYVGTNGLASYLITTPQGHILIDTVMPESTALIETSIG
KLGFKVADIKYVINTHAHIDHTGGLAQIKQETGAQMVAGAKDVPLLEGGFYPGREEERYLNFPPVKVDRAVREGDTVTLG
GVTLTAHETPGHSPGCTSWTTEVKDGDATRSVIFFCSATVALNQLVGRPTYPGIVDDYKKTYAWAKTVHPDVLLAPHPEM
YGMADKRAKIADGAPNPFVKPGEFNAYLDKLEAQFNEGLAKQTAALQSGK

Specific function: Has a high activity against imipenem [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 31262; Mature: 31262

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAATLAWTAGPAAAQSLPDFMKQVIATWNTPTEPFKVIDNIYYVGTNGLASYLITTPQG
CCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCCCEEEEEECCCC
HILIDTVMPESTALIETSIGKLGFKVADIKYVINTHAHIDHTGGLAQIKQETGAQMVAGA
CEEEEEECCCCHHHHHHHHHHHCEEEEEEEEEEECCCEEECCCCHHHHHHHHCCHHHCCC
KDVPLLEGGFYPGREEERYLNFPPVKVDRAVREGDTVTLGGVTLTAHETPGHSPGCTSWT
CCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCEEEEEECCCCCCCCCCCCC
TEVKDGDATRSVIFFCSATVALNQLVGRPTYPGIVDDYKKTYAWAKTVHPDVLLAPHPEM
CCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCHH
YGMADKRAKIADGAPNPFVKPGEFNAYLDKLEAQFNEGLAKQTAALQSGK
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLAATLAWTAGPAAAQSLPDFMKQVIATWNTPTEPFKVIDNIYYVGTNGLASYLITTPQG
CCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCCCEEEEEECCCC
HILIDTVMPESTALIETSIGKLGFKVADIKYVINTHAHIDHTGGLAQIKQETGAQMVAGA
CEEEEEECCCCHHHHHHHHHHHCEEEEEEEEEEECCCEEECCCCHHHHHHHHCCHHHCCC
KDVPLLEGGFYPGREEERYLNFPPVKVDRAVREGDTVTLGGVTLTAHETPGHSPGCTSWT
CCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCEEEEEECCCCCCCCCCCCC
TEVKDGDATRSVIFFCSATVALNQLVGRPTYPGIVDDYKKTYAWAKTVHPDVLLAPHPEM
CCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCHH
YGMADKRAKIADGAPNPFVKPGEFNAYLDKLEAQFNEGLAKQTAALQSGK
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8018721; 3931629; 9811546 [H]