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The map label for this gene is corA [H]

Identifier: 146339183

GI number: 146339183

Start: 2279613

End: 2280590

Strand: Direct

Name: corA [H]

Synonym: BRADO2143

Alternate gene names: 146339183

Gene position: 2279613-2280590 (Clockwise)

Preceding gene: 146339181

Following gene: 146339184

Centisome position: 30.57

GC content: 61.76

Gene sequence:

>978_bases
ATGTTCTCGGTGTTCGTCCCGTCCGATCAGGCGTTGAAGAAGGCGGAGATCACCGACCCGGCGGCTCTGCCCGACAATGC
GGTCTGGGTCGACCTCTTCAATCCGAGCGGTGCAGAAGACCGGGCCGTCGAGAAGCTCTCGGGAATCGCGGTCCCGACGC
GGGAGGACATGCAGGAGATCGAGATCTCCAGCCGCCTCTACATCGAGAACGGCGCCCGCTACATGACGGCAACCTTGATG
TGTCACTCGGATACCGACATGCCCCGGACGACGGCGGTGACCTTCATCCTGGCAGGGCACCGCCTGGTGACGGTGCGCTA
CGATCAGCCGCGGCCGTTCGCCGTGGTCGAGGCCAAGCTCGCCCGCAGCTGCGCACCCGGCATTACCGGAGAGATGGTGC
TGATGGAATTGCTCGACGCGGTGATCGATCGCTGCGCCGACATCCTCGAGCGGGTCGGTGCCGACATCGACCAGGTCAGC
CACGAGATCTTCGAGCCGAACAACGAGCGGCACGGCCACGCCAAGCAGTATTCCCAGATCCTGATCGCGATCGGCCGCAA
GGGCGACCTCACCTCGAAAGTACGTGAAAGCCTGGTCTCGATCGGTCGCCTCGTGACCTTTCTTTCCGCCGTCGTCGAAG
GCGTGAAATGGTCAAAGGACATGCGCGAGCAGCTCAAGACCATGCAGCGCGACGTCGCCTCGCTGACCGACCACGCCTCC
TATCTCGCCGGCAAGATCACCTTCGTGCTCGATGCGATGCTCGGTGTCGTCAATCTCGAGCAGAACAACATCATCAAGCT
GTTCTCGGTCATGGCGGTCGTGCTGATGCCGCCGACCTTGATCGCGTCGATCTACGGTATGAACTTCAAGAACATGCCGG
AGCTCGAATGGGCGCACGGCTATCCGATGGCGCTCGTGCTGATGCTGATCTGCGCGATCGTGCCGTACTACATCTTCAAG
CTGAAGAAGTGGCTGTAG

Upstream 100 bases:

>100_bases
GCGAAAAGCCGATGGACCGTTTTGGCAAGCTGCGTCACAAGGCGGCAGCATCCTGCCGGTAATCCGCCGAAAACCCCATC
GCGATTCGGAGTCTCCCTTC

Downstream 100 bases:

>100_bases
CCGCGCTGATTGAAGGGAAGTCAGAGCCCGGGCTTGTCGCGGGTGCGAGCACGCCGGTCTCGTGCTGATGCGGCAGAGCA
AGCCTCGCCCGCGCCGCGAT

Product: putative magnesium/cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MFSVFVPSDQALKKAEITDPAALPDNAVWVDLFNPSGAEDRAVEKLSGIAVPTREDMQEIEISSRLYIENGARYMTATLM
CHSDTDMPRTTAVTFILAGHRLVTVRYDQPRPFAVVEAKLARSCAPGITGEMVLMELLDAVIDRCADILERVGADIDQVS
HEIFEPNNERHGHAKQYSQILIAIGRKGDLTSKVRESLVSIGRLVTFLSAVVEGVKWSKDMREQLKTMQRDVASLTDHAS
YLAGKITFVLDAMLGVVNLEQNNIIKLFSVMAVVLMPPTLIASIYGMNFKNMPELEWAHGYPMALVLMLICAIVPYYIFK
LKKWL

Sequences:

>Translated_325_residues
MFSVFVPSDQALKKAEITDPAALPDNAVWVDLFNPSGAEDRAVEKLSGIAVPTREDMQEIEISSRLYIENGARYMTATLM
CHSDTDMPRTTAVTFILAGHRLVTVRYDQPRPFAVVEAKLARSCAPGITGEMVLMELLDAVIDRCADILERVGADIDQVS
HEIFEPNNERHGHAKQYSQILIAIGRKGDLTSKVRESLVSIGRLVTFLSAVVEGVKWSKDMREQLKTMQRDVASLTDHAS
YLAGKITFVLDAMLGVVNLEQNNIIKLFSVMAVVLMPPTLIASIYGMNFKNMPELEWAHGYPMALVLMLICAIVPYYIFK
LKKWL
>Mature_325_residues
MFSVFVPSDQALKKAEITDPAALPDNAVWVDLFNPSGAEDRAVEKLSGIAVPTREDMQEIEISSRLYIENGARYMTATLM
CHSDTDMPRTTAVTFILAGHRLVTVRYDQPRPFAVVEAKLARSCAPGITGEMVLMELLDAVIDRCADILERVGADIDQVS
HEIFEPNNERHGHAKQYSQILIAIGRKGDLTSKVRESLVSIGRLVTFLSAVVEGVKWSKDMREQLKTMQRDVASLTDHAS
YLAGKITFVLDAMLGVVNLEQNNIIKLFSVMAVVLMPPTLIASIYGMNFKNMPELEWAHGYPMALVLMLICAIVPYYIFK
LKKWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=327, Percent_Identity=33.3333333333333, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36248; Mature: 36248

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVFVPSDQALKKAEITDPAALPDNAVWVDLFNPSGAEDRAVEKLSGIAVPTREDMQEI
CEEEECCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHH
EISSRLYIENGARYMTATLMCHSDTDMPRTTAVTFILAGHRLVTVRYDQPRPFAVVEAKL
HHHCEEEEECCCEEEEEEEEEECCCCCCHHHHHHHEEECCEEEEEEECCCCCHHHHHHHH
ARSCAPGITGEMVLMELLDAVIDRCADILERVGADIDQVSHEIFEPNNERHGHAKQYSQI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHH
LIAIGRKGDLTSKVRESLVSIGRLVTFLSAVVEGVKWSKDMREQLKTMQRDVASLTDHAS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YLAGKITFVLDAMLGVVNLEQNNIIKLFSVMAVVLMPPTLIASIYGMNFKNMPELEWAHG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC
YPMALVLMLICAIVPYYIFKLKKWL
CHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFSVFVPSDQALKKAEITDPAALPDNAVWVDLFNPSGAEDRAVEKLSGIAVPTREDMQEI
CEEEECCCHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHH
EISSRLYIENGARYMTATLMCHSDTDMPRTTAVTFILAGHRLVTVRYDQPRPFAVVEAKL
HHHCEEEEECCCEEEEEEEEEECCCCCCHHHHHHHEEECCEEEEEEECCCCCHHHHHHHH
ARSCAPGITGEMVLMELLDAVIDRCADILERVGADIDQVSHEIFEPNNERHGHAKQYSQI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHH
LIAIGRKGDLTSKVRESLVSIGRLVTFLSAVVEGVKWSKDMREQLKTMQRDVASLTDHAS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
YLAGKITFVLDAMLGVVNLEQNNIIKLFSVMAVVLMPPTLIASIYGMNFKNMPELEWAHG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCC
YPMALVLMLICAIVPYYIFKLKKWL
CHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]