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The map label for this gene is erfK [H]

Identifier: 146339182

GI number: 146339182

Start: 2278588

End: 2279268

Strand: Reverse

Name: erfK [H]

Synonym: BRADO2142

Alternate gene names: 146339182

Gene position: 2279268-2278588 (Counterclockwise)

Preceding gene: 146339185

Following gene: 146339180

Centisome position: 30.57

GC content: 62.7

Gene sequence:

>681_bases
ATGTCGCTGAAGGTGAAACTCGGACTCCTGGCCGCGGGCCTGATGCTGTCGGGCTGTATGCAGGCCACGACGTATGAGGC
CACCAACACCCAGGCGTTCAAGCCGAAAGACAAAGAGCTTCTGGCGAAGATCCGCTACACCAACACGCCGGTCGCGGAAC
CCTATCGCCGGGCCATCGTCGACTATCATCGCAAGGAAGCACCGGGCTCGATCGTCGTCGATTCCGACAGCCACTACCTC
TATTACGTACTCGATGGCGGCAAGGCGATCCGTTACGGCATCACCGTCGGTGAAGAGGCCATGGCGTGGTCGGGCATTGC
CAAGGTGGGCGCCATGACGGAATGGCCGGCCTGGCATCCGACCAAGGGCGAGATCGAGCGCCTGGGTGTGCCGACCTTCG
TCGCCCCGGGTCCCGACAATCCGATGGGCTCGCGCGCGATGTACCTCTATGCCAACGGCAAGGACACGCTGTTCCGCATC
CACGGTACCAACCAGCCGGAATATATCGGCGCCTCGATCTCGTCGGGCTGCATCCGCCTGACCAACGAGGACGCGATCGA
CCTCTACAACCGGGTCAAGGTCGGCACCATCGTCGTGGTCCTGGATCCGAAGAAGGGCGATTCGCCCTACAAGCCGCAAA
TGGCCCTGCAGGGCGGCGGCACCTACGCCGCGATGCAATAA

Upstream 100 bases:

>100_bases
GCATCAGAGTCGATTTTGACGATAATGGGACATGTGGAATCGCGCTGCAGTGGCGCGGCCGTGTCATTGCAACGTCAGCT
GTCAATTGGAAATTGGTGAC

Downstream 100 bases:

>100_bases
GCATCTGCGCTCAACGGAATCAAAAGCCGAGAAACGCGTTTATCACCCTTTCCAAAGGCGCCGGTCACCCCGGCGCCTTT
TTGTTTGGGCGCAAGGGACC

Product: putative ErfK/YbiS/YcfS/YnhG signal peptide

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MSLKVKLGLLAAGLMLSGCMQATTYEATNTQAFKPKDKELLAKIRYTNTPVAEPYRRAIVDYHRKEAPGSIVVDSDSHYL
YYVLDGGKAIRYGITVGEEAMAWSGIAKVGAMTEWPAWHPTKGEIERLGVPTFVAPGPDNPMGSRAMYLYANGKDTLFRI
HGTNQPEYIGASISSGCIRLTNEDAIDLYNRVKVGTIVVVLDPKKGDSPYKPQMALQGGGTYAAMQ

Sequences:

>Translated_226_residues
MSLKVKLGLLAAGLMLSGCMQATTYEATNTQAFKPKDKELLAKIRYTNTPVAEPYRRAIVDYHRKEAPGSIVVDSDSHYL
YYVLDGGKAIRYGITVGEEAMAWSGIAKVGAMTEWPAWHPTKGEIERLGVPTFVAPGPDNPMGSRAMYLYANGKDTLFRI
HGTNQPEYIGASISSGCIRLTNEDAIDLYNRVKVGTIVVVLDPKKGDSPYKPQMALQGGGTYAAMQ
>Mature_225_residues
SLKVKLGLLAAGLMLSGCMQATTYEATNTQAFKPKDKELLAKIRYTNTPVAEPYRRAIVDYHRKEAPGSIVVDSDSHYLY
YVLDGGKAIRYGITVGEEAMAWSGIAKVGAMTEWPAWHPTKGEIERLGVPTFVAPGPDNPMGSRAMYLYANGKDTLFRIH
GTNQPEYIGASISSGCIRLTNEDAIDLYNRVKVGTIVVVLDPKKGDSPYKPQMALQGGGTYAAMQ

Specific function: Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp [H]

COG id: COG1376

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YkuD family [H]

Homologues:

Organism=Escherichia coli, GI1788299, Length=158, Percent_Identity=36.0759493670886, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787968, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787040, Length=142, Percent_Identity=38.0281690140845, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787356, Length=141, Percent_Identity=32.6241134751773, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005490 [H]

Pfam domain/function: PF03734 YkuD [H]

EC number: NA

Molecular weight: Translated: 24640; Mature: 24508

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKVKLGLLAAGLMLSGCMQATTYEATNTQAFKPKDKELLAKIRYTNTPVAEPYRRAIV
CCEEEEHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHEEEECCCCCCCCHHHHHHH
DYHRKEAPGSIVVDSDSHYLYYVLDGGKAIRYGITVGEEAMAWSGIAKVGAMTEWPAWHP
HHHHCCCCCCEEEECCCCEEEEEEECCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
TKGEIERLGVPTFVAPGPDNPMGSRAMYLYANGKDTLFRIHGTNQPEYIGASISSGCIRL
CCCCHHHCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEEE
TNEDAIDLYNRVKVGTIVVVLDPKKGDSPYKPQMALQGGGTYAAMQ
CCCCHHHHHHEEEEEEEEEEECCCCCCCCCCCEEEEECCCEEEECC
>Mature Secondary Structure 
SLKVKLGLLAAGLMLSGCMQATTYEATNTQAFKPKDKELLAKIRYTNTPVAEPYRRAIV
CEEEEHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHEEEECCCCCCCCHHHHHHH
DYHRKEAPGSIVVDSDSHYLYYVLDGGKAIRYGITVGEEAMAWSGIAKVGAMTEWPAWHP
HHHHCCCCCCEEEECCCCEEEEEEECCCEEEEEEEECCHHHHHHHHHHHCCCCCCCCCCC
TKGEIERLGVPTFVAPGPDNPMGSRAMYLYANGKDTLFRIHGTNQPEYIGASISSGCIRL
CCCCHHHCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCEEECCCCCCEEEE
TNEDAIDLYNRVKVGTIVVVLDPKKGDSPYKPQMALQGGGTYAAMQ
CCCCHHHHHHEEEEEEEEEEECCCCCCCCCCCEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592411; 9097040; 9278503; 9298646 [H]