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The map label for this gene is uxuA [H]

Identifier: 146338864

GI number: 146338864

Start: 1927315

End: 1928511

Strand: Direct

Name: uxuA [H]

Synonym: BRADO1803

Alternate gene names: 146338864

Gene position: 1927315-1928511 (Clockwise)

Preceding gene: 146338862

Following gene: 146338865

Centisome position: 25.85

GC content: 66.83

Gene sequence:

>1197_bases
ATGCAACAGACGTGGCGCTGGTTCGGACCGGAGGATCCCATCACCCTGCCGCAGGTCCGCCAGACCGGCGCGACCGGCAT
CGTCACGGCGCTGCATCACATTCCCTATGGCGAGGTGTGGAGCACCGACGAGATCATCAGACGCCTCGGGATGATCGAGC
AAGACTCGTCATTGCGATTGCGGTGGAGCGTTGTCGAAAGCCTGCCGGTGTCGGAGGCGATCAAACTGGGCGAAGGTGAT
CTCACCCCGCTGTTCGACAATTATCGGCAGTCGCTGCGCAACCTCGCGGCCTGCGGCATCACCACCGTGTGCTACAATTT
CATGGCCGTGCTGGACTGGACGCGGACGGAGCTTGCGCATCGCCTGCCGGGCGGCGCCACGGCGCTGCGCTTCGACATGG
ATCGTCTCGCCGCATTCGACTGCTATATCCTGGAGCGCCCAGGCGCCGAGGCCGAGTTCTCCGCCGACGTGCTCGACCGC
GCCAAGGCGTGGGTGGCGCAGGCCTCGGAATCCGACAAGGACCGGCTGCTCGCGACCATCATGGCGGGCCTGCCCGGCGC
CTATGAGCGCTACGACGTGCCCGGCCTGCGCCGCATGCTGGAGAAGTACCGTGGCATCGGCCATGCCGAGCTACGCGCCA
ACTACGCGCGCTTCCTGCGCGAGGTTGTGCCGACGGCGGAGGATTGCGGCGTCAGCCTGTGCGTGCATCCGGACGATCCG
CCGCGCGACCTGTTCGGTTTGCCGCGCGTGGTGTCGTCGGCCGATGATCTGCAGTTCATCGTCGATGCCGCGCCGTCGAA
GTCGAACGGCCTCACCTTCTGCACCGGCGCGCTCGGCGCCGGCGGCCAGAACAACGTGCCGGCGATGGCCGCGCGCTTCG
CGCCGCACATCCGCTTCGTACATTTGCGCAACGTCACCAAGATGCTCGACGGCTCCTTCATGGAGGCGGAGCATCTGCGC
GGCGATGTCGACATGGTTAACGTGGTCACGATGTTGTTGACGGAGCAGGCCCGCCGCAAGACGGAGGGCGAGCCGGACTG
GCGTATCCCGTTCCGGCCCGATCACGGTCATGAGCTGGCCGACGACATCGGCCGCGGCACCCATCCCGGCTATCCGCTGG
TCGGCCGGCTCAAGGGCCTTGCCGAGATCCGAGGCGTAATGACGGCGGTGGCGGCCATCAACCGCTTGCCGGTCTGA

Upstream 100 bases:

>100_bases
CGGCGTCGCAGGCGCCAAGCCCATTTCATGACGCAAAGCAGTGTGATCGATAGGCTGGAATCGGCGCGCGACAGGCCGGC
GGACGCAGGGAGGGAATGAG

Downstream 100 bases:

>100_bases
TCGCGTCGTGATCTAGGATCGACGGAGAAGACCAGACAGGGAGACCCGGCCCATGCGTGCCGTCGTGATTCACGCGCCCA
AGGATCTGCGCATCGACAGC

Product: mannonate hydrolase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MQQTWRWFGPEDPITLPQVRQTGATGIVTALHHIPYGEVWSTDEIIRRLGMIEQDSSLRLRWSVVESLPVSEAIKLGEGD
LTPLFDNYRQSLRNLAACGITTVCYNFMAVLDWTRTELAHRLPGGATALRFDMDRLAAFDCYILERPGAEAEFSADVLDR
AKAWVAQASESDKDRLLATIMAGLPGAYERYDVPGLRRMLEKYRGIGHAELRANYARFLREVVPTAEDCGVSLCVHPDDP
PRDLFGLPRVVSSADDLQFIVDAAPSKSNGLTFCTGALGAGGQNNVPAMAARFAPHIRFVHLRNVTKMLDGSFMEAEHLR
GDVDMVNVVTMLLTEQARRKTEGEPDWRIPFRPDHGHELADDIGRGTHPGYPLVGRLKGLAEIRGVMTAVAAINRLPV

Sequences:

>Translated_398_residues
MQQTWRWFGPEDPITLPQVRQTGATGIVTALHHIPYGEVWSTDEIIRRLGMIEQDSSLRLRWSVVESLPVSEAIKLGEGD
LTPLFDNYRQSLRNLAACGITTVCYNFMAVLDWTRTELAHRLPGGATALRFDMDRLAAFDCYILERPGAEAEFSADVLDR
AKAWVAQASESDKDRLLATIMAGLPGAYERYDVPGLRRMLEKYRGIGHAELRANYARFLREVVPTAEDCGVSLCVHPDDP
PRDLFGLPRVVSSADDLQFIVDAAPSKSNGLTFCTGALGAGGQNNVPAMAARFAPHIRFVHLRNVTKMLDGSFMEAEHLR
GDVDMVNVVTMLLTEQARRKTEGEPDWRIPFRPDHGHELADDIGRGTHPGYPLVGRLKGLAEIRGVMTAVAAINRLPV
>Mature_398_residues
MQQTWRWFGPEDPITLPQVRQTGATGIVTALHHIPYGEVWSTDEIIRRLGMIEQDSSLRLRWSVVESLPVSEAIKLGEGD
LTPLFDNYRQSLRNLAACGITTVCYNFMAVLDWTRTELAHRLPGGATALRFDMDRLAAFDCYILERPGAEAEFSADVLDR
AKAWVAQASESDKDRLLATIMAGLPGAYERYDVPGLRRMLEKYRGIGHAELRANYARFLREVVPTAEDCGVSLCVHPDDP
PRDLFGLPRVVSSADDLQFIVDAAPSKSNGLTFCTGALGAGGQNNVPAMAARFAPHIRFVHLRNVTKMLDGSFMEAEHLR
GDVDMVNVVTMLLTEQARRKTEGEPDWRIPFRPDHGHELADDIGRGTHPGYPLVGRLKGLAEIRGVMTAVAAINRLPV

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=391, Percent_Identity=52.6854219948849, Blast_Score=428, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 44128; Mature: 44128

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTWRWFGPEDPITLPQVRQTGATGIVTALHHIPYGEVWSTDEIIRRLGMIEQDSSLRL
CCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEE
RWSVVESLPVSEAIKLGEGDLTPLFDNYRQSLRNLAACGITTVCYNFMAVLDWTRTELAH
EEHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLPGGATALRFDMDRLAAFDCYILERPGAEAEFSADVLDRAKAWVAQASESDKDRLLATI
HCCCCCEEEEECHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
MAGLPGAYERYDVPGLRRMLEKYRGIGHAELRANYARFLREVVPTAEDCGVSLCVHPDDP
HHCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCC
PRDLFGLPRVVSSADDLQFIVDAAPSKSNGLTFCTGALGAGGQNNVPAMAARFAPHIRFV
CHHHHCCHHHHCCCCHHEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCEEE
HLRNVTKMLDGSFMEAEHLRGDVDMVNVVTMLLTEQARRKTEGEPDWRIPFRPDHGHELA
HHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
DDIGRGTHPGYPLVGRLKGLAEIRGVMTAVAAINRLPV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQTWRWFGPEDPITLPQVRQTGATGIVTALHHIPYGEVWSTDEIIRRLGMIEQDSSLRL
CCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEE
RWSVVESLPVSEAIKLGEGDLTPLFDNYRQSLRNLAACGITTVCYNFMAVLDWTRTELAH
EEHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLPGGATALRFDMDRLAAFDCYILERPGAEAEFSADVLDRAKAWVAQASESDKDRLLATI
HCCCCCEEEEECHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
MAGLPGAYERYDVPGLRRMLEKYRGIGHAELRANYARFLREVVPTAEDCGVSLCVHPDDP
HHCCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCCEEEEECCCCC
PRDLFGLPRVVSSADDLQFIVDAAPSKSNGLTFCTGALGAGGQNNVPAMAARFAPHIRFV
CHHHHCCHHHHCCCCHHEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCCEEE
HLRNVTKMLDGSFMEAEHLRGDVDMVNVVTMLLTEQARRKTEGEPDWRIPFRPDHGHELA
HHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
DDIGRGTHPGYPLVGRLKGLAEIRGVMTAVAAINRLPV
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA