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The map label for this gene is glcD [H]

Identifier: 146338862

GI number: 146338862

Start: 1924169

End: 1925584

Strand: Direct

Name: glcD [H]

Synonym: BRADO1801

Alternate gene names: 146338862

Gene position: 1924169-1925584 (Clockwise)

Preceding gene: 146338861

Following gene: 146338864

Centisome position: 25.8

GC content: 68.64

Gene sequence:

>1416_bases
ATGACGAAGCTGATCACCACGTTGCAGGGTCTTGTCGGAGCCGCTCATGTCCTGACCGCGCCCGAGGATCAGGCGAGTTA
TCTGCGCGACTGGCTCGGCAAGTATAATGGTGCAGCGATTGCCGTGGTGAGGCCCGCGTCGACCGAAGAGGTCGCGGCCG
TGATGGCGGCCTGCGCCGAGGCGGGTGTCGCCGTGGTGCCGCAGGGCGGTCACACCAGCCTGTCCGGCGGCGCCACGCCG
GATGCGAGCGGCAGCGCGATCGTGCTGTCGCTGTCGCGGATGAACAGGATTCGCGCGGTCGATGCGATCGGACAGACCAT
GGTGGCCGACGCCGGGGTCGTGCTCGCCAAGGTGCAGGATGCCGCGCGCGAGGCGGGCCTGTTCTTTCCGCTGAGCCTTG
GCTCCGAGGGCAGCTGCACCGTCGGGGGCAATCTCGCGGCCAATGCCGGCGGCGTCGCCGTGCTGCGCTATGGCGTGATG
CGCGAACTCACGCTCGGGCTCGAAGTCGTGCTGCCGGACGGGCGCATCTGGGACGGCCTGCGCTCCCTGCGCAAGGACAA
CACCGGCTATGCGCTGCGCGATCTCTTCATCGGTTCGGAAGGCACGCTCGGCATCATCACGGGCGCGGTGCTGAAGCTGT
TCCCGCAGCCGACCGCCCGCGCCACGGCCTTCGTAGCGGTCGCCGATGCGGCCGCCGCCCTCAAGCTGCTGCAGAGGTCG
CGCGCCCGTTGCGGCGATCGCCTGACGGCATTTGAATTCCTCACCGCAGCGACGCTGGAAATGATCATGCGGCAAATTCC
GGACGCGCGGCTGCCGTTCGCGGCAGTGCCTGAGGCGGCCGTGCTGATCGAATTGAGCGATATCGGCGAGGAGGCCGCGC
TGACGGCCCGCCTCGAGACCACGCTGACCGACGCCATGACGGAGGGACTTGTCGCCGACGCCGTCATCGCGCAGGACGGC
ACCCAGGCCAAGGCGTTCTGGCGCGTGCGCGAGAGCGTGTCGGAAGCCCTGGTGCGTGAGGGCAAGGCGCTGAAGCACGA
CGTCGCCGTGCCCGTGGCCGAGATCGCCGATTTCGTCGATGTCATGGACGCGGTGGTCGGTGCGGCGCTGCCCGGCATCC
GCCCCATGGTGTTCGGCCATCTCGGCGACGGCAATCTGCACTACAATCTGATGCGCCCGCTCGACATGAGCGAGGCCGAG
TTCTACGAGCGCGGCCCGCGCATCACCCGCCTCGTCCACGACGAGATCACCCGCCGGCGCGGCTCGATCAGCGCCGAGCA
CGGCATCGGCCAGCTCCGTACCGCCGAGATGCCGCTGTGCAAGCCGCCGCTCGAGCTTGAGCTGATGCGTCAGCTCAAGC
GTACGCTCGATCCCCGCGGGCTGATGAACCCGGGCAAGCTGCTGCCGAACGTGTAA

Upstream 100 bases:

>100_bases
TTATGGACGGCGGACAACTTGGTATTGGGGGCAATGCCGCCCATCCTGTTAGTTTGCGGTCATCGCAAAACGATCACCGA
CAAGGGTCTCCGCGCGCGTC

Downstream 100 bases:

>100_bases
TTCGGCTTCGCTGCCTCAATCCGCCTCGTAGCCATACACCTCCGGCAGGATGAAGATCGCGGCGAGCAGGCCGGCCAGCG
GGAAGATCGCGACGAACAAT

Product: putative D-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTKLITTLQGLVGAAHVLTAPEDQASYLRDWLGKYNGAAIAVVRPASTEEVAAVMAACAEAGVAVVPQGGHTSLSGGATP
DASGSAIVLSLSRMNRIRAVDAIGQTMVADAGVVLAKVQDAAREAGLFFPLSLGSEGSCTVGGNLAANAGGVAVLRYGVM
RELTLGLEVVLPDGRIWDGLRSLRKDNTGYALRDLFIGSEGTLGIITGAVLKLFPQPTARATAFVAVADAAAALKLLQRS
RARCGDRLTAFEFLTAATLEMIMRQIPDARLPFAAVPEAAVLIELSDIGEEAALTARLETTLTDAMTEGLVADAVIAQDG
TQAKAFWRVRESVSEALVREGKALKHDVAVPVAEIADFVDVMDAVVGAALPGIRPMVFGHLGDGNLHYNLMRPLDMSEAE
FYERGPRITRLVHDEITRRRGSISAEHGIGQLRTAEMPLCKPPLELELMRQLKRTLDPRGLMNPGKLLPNV

Sequences:

>Translated_471_residues
MTKLITTLQGLVGAAHVLTAPEDQASYLRDWLGKYNGAAIAVVRPASTEEVAAVMAACAEAGVAVVPQGGHTSLSGGATP
DASGSAIVLSLSRMNRIRAVDAIGQTMVADAGVVLAKVQDAAREAGLFFPLSLGSEGSCTVGGNLAANAGGVAVLRYGVM
RELTLGLEVVLPDGRIWDGLRSLRKDNTGYALRDLFIGSEGTLGIITGAVLKLFPQPTARATAFVAVADAAAALKLLQRS
RARCGDRLTAFEFLTAATLEMIMRQIPDARLPFAAVPEAAVLIELSDIGEEAALTARLETTLTDAMTEGLVADAVIAQDG
TQAKAFWRVRESVSEALVREGKALKHDVAVPVAEIADFVDVMDAVVGAALPGIRPMVFGHLGDGNLHYNLMRPLDMSEAE
FYERGPRITRLVHDEITRRRGSISAEHGIGQLRTAEMPLCKPPLELELMRQLKRTLDPRGLMNPGKLLPNV
>Mature_470_residues
TKLITTLQGLVGAAHVLTAPEDQASYLRDWLGKYNGAAIAVVRPASTEEVAAVMAACAEAGVAVVPQGGHTSLSGGATPD
ASGSAIVLSLSRMNRIRAVDAIGQTMVADAGVVLAKVQDAAREAGLFFPLSLGSEGSCTVGGNLAANAGGVAVLRYGVMR
ELTLGLEVVLPDGRIWDGLRSLRKDNTGYALRDLFIGSEGTLGIITGAVLKLFPQPTARATAFVAVADAAAALKLLQRSR
ARCGDRLTAFEFLTAATLEMIMRQIPDARLPFAAVPEAAVLIELSDIGEEAALTARLETTLTDAMTEGLVADAVIAQDGT
QAKAFWRVRESVSEALVREGKALKHDVAVPVAEIADFVDVMDAVVGAALPGIRPMVFGHLGDGNLHYNLMRPLDMSEAEF
YERGPRITRLVHDEITRRRGSISAEHGIGQLRTAEMPLCKPPLELELMRQLKRTLDPRGLMNPGKLLPNV

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=464, Percent_Identity=39.6551724137931, Blast_Score=308, Evalue=1e-83,
Organism=Homo sapiens, GI37595756, Length=479, Percent_Identity=31.5240083507307, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI37595754, Length=502, Percent_Identity=30.0796812749004, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4501993, Length=206, Percent_Identity=29.126213592233, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1789351, Length=499, Percent_Identity=29.4589178356713, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994907, Length=219, Percent_Identity=29.6803652968037, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788454, Length=167, Percent_Identity=29.940119760479, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534361, Length=454, Percent_Identity=33.4801762114537, Blast_Score=278, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI71992373, Length=488, Percent_Identity=28.6885245901639, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71992381, Length=486, Percent_Identity=27.9835390946502, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI71992392, Length=368, Percent_Identity=30.4347826086957, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17556096, Length=187, Percent_Identity=27.807486631016, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320023, Length=474, Percent_Identity=36.9198312236287, Blast_Score=332, Evalue=9e-92,
Organism=Saccharomyces cerevisiae, GI6320764, Length=460, Percent_Identity=34.1304347826087, Blast_Score=287, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6320027, Length=445, Percent_Identity=28.9887640449438, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI18921117, Length=472, Percent_Identity=35.5932203389831, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24639277, Length=472, Percent_Identity=35.5932203389831, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24639275, Length=472, Percent_Identity=35.5932203389831, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24653753, Length=217, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49826; Mature: 49695

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLITTLQGLVGAAHVLTAPEDQASYLRDWLGKYNGAAIAVVRPASTEEVAAVMAACAE
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
AGVAVVPQGGHTSLSGGATPDASGSAIVLSLSRMNRIRAVDAIGQTMVADAGVVLAKVQD
CCEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAREAGLFFPLSLGSEGSCTVGGNLAANAGGVAVLRYGVMRELTLGLEVVLPDGRIWDGL
HHHHCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHH
RSLRKDNTGYALRDLFIGSEGTLGIITGAVLKLFPQPTARATAFVAVADAAAALKLLQRS
HHHHCCCCCCEEEHEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RARCGDRLTAFEFLTAATLEMIMRQIPDARLPFAAVPEAAVLIELSDIGEEAALTARLET
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEEEHHCCCHHHHHHHHHH
TLTDAMTEGLVADAVIAQDGTQAKAFWRVRESVSEALVREGKALKHDVAVPVAEIADFVD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHH
VMDAVVGAALPGIRPMVFGHLGDGNLHYNLMRPLDMSEAEFYERGPRITRLVHDEITRRR
HHHHHHHHHCCCCCHHEEEECCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHH
GSISAEHGIGQLRTAEMPLCKPPLELELMRQLKRTLDPRGLMNPGKLLPNV
CCCCHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCC
>Mature Secondary Structure 
TKLITTLQGLVGAAHVLTAPEDQASYLRDWLGKYNGAAIAVVRPASTEEVAAVMAACAE
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
AGVAVVPQGGHTSLSGGATPDASGSAIVLSLSRMNRIRAVDAIGQTMVADAGVVLAKVQD
CCEEEEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAREAGLFFPLSLGSEGSCTVGGNLAANAGGVAVLRYGVMRELTLGLEVVLPDGRIWDGL
HHHHCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHH
RSLRKDNTGYALRDLFIGSEGTLGIITGAVLKLFPQPTARATAFVAVADAAAALKLLQRS
HHHHCCCCCCEEEHEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RARCGDRLTAFEFLTAATLEMIMRQIPDARLPFAAVPEAAVLIELSDIGEEAALTARLET
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCEEEEEEEHHCCCHHHHHHHHHH
TLTDAMTEGLVADAVIAQDGTQAKAFWRVRESVSEALVREGKALKHDVAVPVAEIADFVD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHH
VMDAVVGAALPGIRPMVFGHLGDGNLHYNLMRPLDMSEAEFYERGPRITRLVHDEITRRR
HHHHHHHHHCCCCCHHEEEECCCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHH
GSISAEHGIGQLRTAEMPLCKPPLELELMRQLKRTLDPRGLMNPGKLLPNV
CCCCHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]