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The map label for this gene is exaA [H]

Identifier: 146338773

GI number: 146338773

Start: 1821733

End: 1823511

Strand: Direct

Name: exaA [H]

Synonym: BRADO1707

Alternate gene names: 146338773

Gene position: 1821733-1823511 (Clockwise)

Preceding gene: 146338772

Following gene: 146338774

Centisome position: 24.43

GC content: 64.19

Gene sequence:

>1779_bases
ATGAGGAAACACGTCAGGACCGCCTTGCGTACGGTGCTGCTCGCCAGCGCCGCCTTTGCATGCCTCAACCTCGCATCGCC
GGCGCGCGCCGCTGACGAGATGACGCCGGAGCGGCTGCTCAATGCCGAGAAGGAAGCCGGCAACTGGCTTCATCACCACA
AGAACTATTCCGGCACGCGTTTCTCCACGCTGAAGGAGATCAACAAGGACACCGTCAAGAACCTCAAGGTTGCCTGGACG
ATGCATCTCGGCGGCGTCGAGGGCGGCGGCATCTGGAGCCATGGCGGTCTCGAGGGCACGCCGATCGTCGAGAACGGCAT
GATCTATGTCACCGACGGCTGGGGCTCGGTGTACAAGATCGACGCGCGCGGTGGCAAAGGCCAGCTGGTCTGGAAGATGG
ATCCGAAGACGGATCACGACTGGGCCGGCGCGATCGCCTGCTGCGGCGTCGACAATCGCGGCGTCGCGCTGTGGGGCAAT
CTCGTCATCTCGCACACGCTCGACGGCCGCCTGATCGCAACCAACAAGGAAACCGGGCAGGTCGCCTGGCAGCGCCAGGT
CGCCGATCCCGACAAGGGCGAGGTCATCACCGGCGCGCCGCTGATCGTGAAGAACATGGCGGTGTCCGGTGTCGCCGGTG
CCGAATATGGTATCCGCGGCTGGATCGCCGCGACCGATCTCACCACGCAGAAGGAGGTCTGGCGCACCCACACCATTCCG
GCGAAGGGCGAGCCAGGCAGCGAGACCTGGAAGGACAGCAACGACGCGGCCGCTGCCGGCGGCGGCTCGACCTGGGTGAC
CGGCACCTACGATCCGGCAACCGACACCATCATCTGGGGCGTCGGCAACCCCGGTCCGGACTGGGACAACGCCTATCGTC
CGGGCGACAACCTCTACACCGACAGCTCGCTGGCGCTCGATGCCAACACCGGCAAGATCAAGTGGCACTATCAGCACACG
CCGAACGATCCCTACGACTATGACAGCGTCGCGGAGAACGTTCTTGTCGATGTCCCCACGCCGAACGGCCAGACCCAGAA
GCTCGCACTCGAGGCCGACCGCAACGGCTTCGCCTATGCGATCGACCGCACCAACGGCAAGTTCCTGTGGGGCCTTCCGT
TCGTCAAGAAGGTGACCTGGACCAAGGGACTCGATCCCGAGACCGGCAAGCCGATCGAGTACGATCCGAAGAACCCGGTG
CAGCGCTACAATGCATCGGTCACGCCGCATCGCGAGAACAAGATCGCGGACATCTGCCCCGGCAACATGGGCGGCAAGAA
CTGGCCGCCAACCTCGTACAATCCGGACCTGAAGCTCTGGTACATCCCGGTGATCGAGAGCTGCAACCGGATCACCGTCG
AGGAAGCCACCAAGGACAAGCTCAAGGCGCGCGAGTTCTGGACCGGCGGCGGACCGAGCCAGCCGTTCAAGATCACGGGC
AGCGTGACCGCGATCGACGTCACCACCGGCAAGATCGCCGGCAAGATGGAGACGCCGTTCCCGAACCTCGGCGGCATGCT
GTCGACGCCTGATCTCGTCTTCACCGGCCAGCCCTCGGGCGAGGTGATGGCGCTCGATGCCAAGACGCTGCAGAAGCTGT
GGGAGTTCAACACCGGCGGCGGCGTCAACGCGCCTCCCGTGACCTTCTCGGTCGACGGCAAGCAGTACATCGCGATCCTC
GTCGGTCTCGGTGGTGCCTGGGACAAGTGGTTCATCGAATCCACGCCCGAGCTGAAGAAGATCCAGCCCGGCTCGATGCT
CTACGTCTTCTCGTTGTAA

Upstream 100 bases:

>100_bases
TCGCAAGTCCCCGTAAAGCCTGTTTGTCGCCTGCTACCCTTCGCTGACCGGCGGAGCGGTGTTCGTTCGTACTCATAATC
AAAGATGGGAGAAGGAAACG

Downstream 100 bases:

>100_bases
GCAGATCAAGGAGCGGAGGCGTTGCCTCCGCTCCTTCCTTTTCCCCATTCGGCAAGTAGATCAGATGAAATTCAGTGCGA
TCACGTCCGCCTTGGCCTTG

Product: putative quinoprotein ethanol dehydrogenase

Products: NA

Alternate protein names: QEDH [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MRKHVRTALRTVLLASAAFACLNLASPARAADEMTPERLLNAEKEAGNWLHHHKNYSGTRFSTLKEINKDTVKNLKVAWT
MHLGGVEGGGIWSHGGLEGTPIVENGMIYVTDGWGSVYKIDARGGKGQLVWKMDPKTDHDWAGAIACCGVDNRGVALWGN
LVISHTLDGRLIATNKETGQVAWQRQVADPDKGEVITGAPLIVKNMAVSGVAGAEYGIRGWIAATDLTTQKEVWRTHTIP
AKGEPGSETWKDSNDAAAAGGGSTWVTGTYDPATDTIIWGVGNPGPDWDNAYRPGDNLYTDSSLALDANTGKIKWHYQHT
PNDPYDYDSVAENVLVDVPTPNGQTQKLALEADRNGFAYAIDRTNGKFLWGLPFVKKVTWTKGLDPETGKPIEYDPKNPV
QRYNASVTPHRENKIADICPGNMGGKNWPPTSYNPDLKLWYIPVIESCNRITVEEATKDKLKAREFWTGGGPSQPFKITG
SVTAIDVTTGKIAGKMETPFPNLGGMLSTPDLVFTGQPSGEVMALDAKTLQKLWEFNTGGGVNAPPVTFSVDGKQYIAIL
VGLGGAWDKWFIESTPELKKIQPGSMLYVFSL

Sequences:

>Translated_592_residues
MRKHVRTALRTVLLASAAFACLNLASPARAADEMTPERLLNAEKEAGNWLHHHKNYSGTRFSTLKEINKDTVKNLKVAWT
MHLGGVEGGGIWSHGGLEGTPIVENGMIYVTDGWGSVYKIDARGGKGQLVWKMDPKTDHDWAGAIACCGVDNRGVALWGN
LVISHTLDGRLIATNKETGQVAWQRQVADPDKGEVITGAPLIVKNMAVSGVAGAEYGIRGWIAATDLTTQKEVWRTHTIP
AKGEPGSETWKDSNDAAAAGGGSTWVTGTYDPATDTIIWGVGNPGPDWDNAYRPGDNLYTDSSLALDANTGKIKWHYQHT
PNDPYDYDSVAENVLVDVPTPNGQTQKLALEADRNGFAYAIDRTNGKFLWGLPFVKKVTWTKGLDPETGKPIEYDPKNPV
QRYNASVTPHRENKIADICPGNMGGKNWPPTSYNPDLKLWYIPVIESCNRITVEEATKDKLKAREFWTGGGPSQPFKITG
SVTAIDVTTGKIAGKMETPFPNLGGMLSTPDLVFTGQPSGEVMALDAKTLQKLWEFNTGGGVNAPPVTFSVDGKQYIAIL
VGLGGAWDKWFIESTPELKKIQPGSMLYVFSL
>Mature_592_residues
MRKHVRTALRTVLLASAAFACLNLASPARAADEMTPERLLNAEKEAGNWLHHHKNYSGTRFSTLKEINKDTVKNLKVAWT
MHLGGVEGGGIWSHGGLEGTPIVENGMIYVTDGWGSVYKIDARGGKGQLVWKMDPKTDHDWAGAIACCGVDNRGVALWGN
LVISHTLDGRLIATNKETGQVAWQRQVADPDKGEVITGAPLIVKNMAVSGVAGAEYGIRGWIAATDLTTQKEVWRTHTIP
AKGEPGSETWKDSNDAAAAGGGSTWVTGTYDPATDTIIWGVGNPGPDWDNAYRPGDNLYTDSSLALDANTGKIKWHYQHT
PNDPYDYDSVAENVLVDVPTPNGQTQKLALEADRNGFAYAIDRTNGKFLWGLPFVKKVTWTKGLDPETGKPIEYDPKNPV
QRYNASVTPHRENKIADICPGNMGGKNWPPTSYNPDLKLWYIPVIESCNRITVEEATKDKLKAREFWTGGGPSQPFKITG
SVTAIDVTTGKIAGKMETPFPNLGGMLSTPDLVFTGQPSGEVMALDAKTLQKLWEFNTGGGVNAPPVTFSVDGKQYIAIL
VGLGGAWDKWFIESTPELKKIQPGSMLYVFSL

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is a very poor substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=624, Percent_Identity=24.8397435897436, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 64349; Mature: 64349

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHVRTALRTVLLASAAFACLNLASPARAADEMTPERLLNAEKEAGNWLHHHKNYSGTR
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCHHHHCCHHHHCCCCCCCH
FSTLKEINKDTVKNLKVAWTMHLGGVEGGGIWSHGGLEGTPIVENGMIYVTDGWGSVYKI
HHHHHHHCHHHHCCEEEEEEEEECCCCCCCEECCCCCCCCCEEECCEEEEECCCCCEEEE
DARGGKGQLVWKMDPKTDHDWAGAIACCGVDNRGVALWGNLVISHTLDGRLIATNKETGQ
ECCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEEEEEEECCCEEEEECCCCCC
VAWQRQVADPDKGEVITGAPLIVKNMAVSGVAGAEYGIRGWIAATDLTTQKEVWRTHTIP
EEEEHHCCCCCCCCEEECCCCEEEHHECCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCC
AKGEPGSETWKDSNDAAAAGGGSTWVTGTYDPATDTIIWGVGNPGPDWDNAYRPGDNLYT
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
DSSLALDANTGKIKWHYQHTPNDPYDYDSVAENVLVDVPTPNGQTQKLALEADRNGFAYA
CCEEEEECCCCEEEEEEECCCCCCCCHHHHHCCEEEECCCCCCCCEEEEEEECCCCEEEE
IDRTNGKFLWGLPFVKKVTWTKGLDPETGKPIEYDPKNPVQRYNASVTPHRENKIADICP
EECCCCEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
GNMGGKNWPPTSYNPDLKLWYIPVIESCNRITVEEATKDKLKAREFWTGGGPSQPFKITG
CCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHEECCCCCCCCEEEEC
SVTAIDVTTGKIAGKMETPFPNLGGMLSTPDLVFTGQPSGEVMALDAKTLQKLWEFNTGG
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECHHHHHHHHCCCCCC
GVNAPPVTFSVDGKQYIAILVGLGGAWDKWFIESTPELKKIQPGSMLYVFSL
CCCCCCEEEEECCCEEEEEEEECCCCCCHHEECCCCCHHCCCCCCEEEEEEC
>Mature Secondary Structure
MRKHVRTALRTVLLASAAFACLNLASPARAADEMTPERLLNAEKEAGNWLHHHKNYSGTR
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCHHHHCCHHHHCCCCCCCH
FSTLKEINKDTVKNLKVAWTMHLGGVEGGGIWSHGGLEGTPIVENGMIYVTDGWGSVYKI
HHHHHHHCHHHHCCEEEEEEEEECCCCCCCEECCCCCCCCCEEECCEEEEECCCCCEEEE
DARGGKGQLVWKMDPKTDHDWAGAIACCGVDNRGVALWGNLVISHTLDGRLIATNKETGQ
ECCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEEEEEEEEEEECCCEEEEECCCCCC
VAWQRQVADPDKGEVITGAPLIVKNMAVSGVAGAEYGIRGWIAATDLTTQKEVWRTHTIP
EEEEHHCCCCCCCCEEECCCCEEEHHECCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCC
AKGEPGSETWKDSNDAAAAGGGSTWVTGTYDPATDTIIWGVGNPGPDWDNAYRPGDNLYT
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
DSSLALDANTGKIKWHYQHTPNDPYDYDSVAENVLVDVPTPNGQTQKLALEADRNGFAYA
CCEEEEECCCCEEEEEEECCCCCCCCHHHHHCCEEEECCCCCCCCEEEEEEECCCCEEEE
IDRTNGKFLWGLPFVKKVTWTKGLDPETGKPIEYDPKNPVQRYNASVTPHRENKIADICP
EECCCCEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCC
GNMGGKNWPPTSYNPDLKLWYIPVIESCNRITVEEATKDKLKAREFWTGGGPSQPFKITG
CCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEHHHHHHHHHHHHEECCCCCCCCEEEEC
SVTAIDVTTGKIAGKMETPFPNLGGMLSTPDLVFTGQPSGEVMALDAKTLQKLWEFNTGG
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECHHHHHHHHCCCCCC
GVNAPPVTFSVDGKQYIAILVGLGGAWDKWFIESTPELKKIQPGSMLYVFSL
CCCCCCEEEEECCCEEEEEEEECCCCCCHHEECCCCCHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826187; 10984043; 10075429; 10736230 [H]