Click here to switch to the map view.

The map label for this gene is hypD [H]

Identifier: 146338765

GI number: 146338765

Start: 1813521

End: 1814648

Strand: Direct

Name: hypD [H]

Synonym: BRADO1699

Alternate gene names: 146338765

Gene position: 1813521-1814648 (Clockwise)

Preceding gene: 146338764

Following gene: 146338766

Centisome position: 24.32

GC content: 65.69

Gene sequence:

>1128_bases
ATGAAATATGCCGACGAGTTTCGCGACAAGGAGCTGGCACTGGGGCTCGCGCGCGCCATCCGCGCCAAGGCGGACCCTGC
GCGCGCCTATCGCTTCATGGAGTTCTGCGGCGGTCATACGCACGCGATCGCACGCTATGGCCTTGAAGACATGCTGCCGG
GCAATGTCCGCATGATCCACGGACCGGGCTGCCCGGTCTGCGTGCTGCCGGCTGGCCGCATCGACATGGCGATCGCGCTC
GCGGAACGGCCAGAGGTCATTCTGTGCGTCTATGGCGACCTGATGCGCGTACCGGGCTCGCGCGGCGCGTCGCTGCTGAA
GGCCAAGGCGCGCGGCGCCGACATCCGCATGGTCTATTCCACGCTCGACGCCATTGCGCTGGCCGAGCAGAACCCCGGCC
GCCAGATCGTGTTCTTCGCCATCGGCTTCGAGACCACGACGCCGCCGACGGCGGTGATGATCCGCGCCGCGGAGAAGAAG
GAGCTCGCGAATTTCAGCGTGTTCTGCAATCACGTGCTGACGCCCCCGGCGATGCGCGCAATTCTCGACAGCGACGTGCC
GATCGAGATCGGCGGGTTCGTCGGCCCGGCGCATGTCTCGACCGTGATCGGCACCGAGCCCTACGCGCCGTTCGCGCGCG
ACGATGGCAAGCCGGTGGTGATTGCCGGCTTCGAGCCGCTCGACATGATGCAGGCCATCCTGATGCTGATCGAGCAGGTC
AATGACGGCCGCCACGAGGTCGAGAACCAGTACCGCCGCGCCGTCACGGGCAGCGGCAATCAGCGTGCGATGAAGCAAAT
GGCAGAGATCTTCGAGTTGCGCGACCAGTTCGAGTGGCGTGGTCTCGGCAGTATTCCCGCGAGTGCCTTGAAGCTGCGGC
CTGCCTTTGCGCATTTCGATGCCGAGCTGCGCTTTGCAATGCGCGAGCTGGTGGTGGCCGACAATCCGGCCTGCGAATGC
CCCGCCATCCTGCGTGGGCTGAAGAAACCGGTGGACTGCAAGCTGTTCGGCACGGCTTGCACGCCTGAGACGCCGATCGG
CTCCTGCATGGTGTCGTCGGAAGGCGCCTGCGCGGCGCATTGGACTTATGGCCGCTTCCGCGACCATCAGCGGAGGCTTG
CCTCATGA

Upstream 100 bases:

>100_bases
TCCATGTCGGCCATGCGCTGACGAAGATCGATCCGGAGGAGGCGCGCGAAACGCTCGATCTGCTCCGCCAGATGGGGGCA
GCAGCCGCGGAGGCCGCACC

Downstream 100 bases:

>100_bases
GCATGCATCAGCGCCGGCTCGACCTGAAGAACGGCTGCGTCGACCTCTCGCACGGCGCCGGTGGCCGCGCGATGGCGCAG
CTGATTGCCGGTCTGTTCCA

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MKYADEFRDKELALGLARAIRAKADPARAYRFMEFCGGHTHAIARYGLEDMLPGNVRMIHGPGCPVCVLPAGRIDMAIAL
AERPEVILCVYGDLMRVPGSRGASLLKAKARGADIRMVYSTLDAIALAEQNPGRQIVFFAIGFETTTPPTAVMIRAAEKK
ELANFSVFCNHVLTPPAMRAILDSDVPIEIGGFVGPAHVSTVIGTEPYAPFARDDGKPVVIAGFEPLDMMQAILMLIEQV
NDGRHEVENQYRRAVTGSGNQRAMKQMAEIFELRDQFEWRGLGSIPASALKLRPAFAHFDAELRFAMRELVVADNPACEC
PAILRGLKKPVDCKLFGTACTPETPIGSCMVSSEGACAAHWTYGRFRDHQRRLAS

Sequences:

>Translated_375_residues
MKYADEFRDKELALGLARAIRAKADPARAYRFMEFCGGHTHAIARYGLEDMLPGNVRMIHGPGCPVCVLPAGRIDMAIAL
AERPEVILCVYGDLMRVPGSRGASLLKAKARGADIRMVYSTLDAIALAEQNPGRQIVFFAIGFETTTPPTAVMIRAAEKK
ELANFSVFCNHVLTPPAMRAILDSDVPIEIGGFVGPAHVSTVIGTEPYAPFARDDGKPVVIAGFEPLDMMQAILMLIEQV
NDGRHEVENQYRRAVTGSGNQRAMKQMAEIFELRDQFEWRGLGSIPASALKLRPAFAHFDAELRFAMRELVVADNPACEC
PAILRGLKKPVDCKLFGTACTPETPIGSCMVSSEGACAAHWTYGRFRDHQRRLAS
>Mature_375_residues
MKYADEFRDKELALGLARAIRAKADPARAYRFMEFCGGHTHAIARYGLEDMLPGNVRMIHGPGCPVCVLPAGRIDMAIAL
AERPEVILCVYGDLMRVPGSRGASLLKAKARGADIRMVYSTLDAIALAEQNPGRQIVFFAIGFETTTPPTAVMIRAAEKK
ELANFSVFCNHVLTPPAMRAILDSDVPIEIGGFVGPAHVSTVIGTEPYAPFARDDGKPVVIAGFEPLDMMQAILMLIEQV
NDGRHEVENQYRRAVTGSGNQRAMKQMAEIFELRDQFEWRGLGSIPASALKLRPAFAHFDAELRFAMRELVVADNPACEC
PAILRGLKKPVDCKLFGTACTPETPIGSCMVSSEGACAAHWTYGRFRDHQRRLAS

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=368, Percent_Identity=48.3695652173913, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41064; Mature: 41064

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYADEFRDKELALGLARAIRAKADPARAYRFMEFCGGHTHAIARYGLEDMLPGNVRMIH
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCHHHCCCCCEEEEE
GPGCPVCVLPAGRIDMAIALAERPEVILCVYGDLMRVPGSRGASLLKAKARGADIRMVYS
CCCCCEEEECCCCCEEEEEECCCCCEEEEECCHHHHCCCCCCHHHHHHHCCCCCEEHHHH
TLDAIALAEQNPGRQIVFFAIGFETTTPPTAVMIRAAEKKELANFSVFCNHVLTPPAMRA
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHH
ILDSDVPIEIGGFVGPAHVSTVIGTEPYAPFARDDGKPVVIAGFEPLDMMQAILMLIEQV
HHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NDGRHEVENQYRRAVTGSGNQRAMKQMAEIFELRDQFEWRGLGSIPASALKLRPAFAHFD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCHHHHHHH
AELRFAMRELVVADNPACECPAILRGLKKPVDCKLFGTACTPETPIGSCMVSSEGACAAH
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCEEEE
WTYGRFRDHQRRLAS
CCHHHHHHHHHHHCC
>Mature Secondary Structure
MKYADEFRDKELALGLARAIRAKADPARAYRFMEFCGGHTHAIARYGLEDMLPGNVRMIH
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCHHHCCCCCEEEEE
GPGCPVCVLPAGRIDMAIALAERPEVILCVYGDLMRVPGSRGASLLKAKARGADIRMVYS
CCCCCEEEECCCCCEEEEEECCCCCEEEEECCHHHHCCCCCCHHHHHHHCCCCCEEHHHH
TLDAIALAEQNPGRQIVFFAIGFETTTPPTAVMIRAAEKKELANFSVFCNHVLTPPAMRA
HHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHHHH
ILDSDVPIEIGGFVGPAHVSTVIGTEPYAPFARDDGKPVVIAGFEPLDMMQAILMLIEQV
HHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NDGRHEVENQYRRAVTGSGNQRAMKQMAEIFELRDQFEWRGLGSIPASALKLRPAFAHFD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCHHHHHHH
AELRFAMRELVVADNPACECPAILRGLKKPVDCKLFGTACTPETPIGSCMVSSEGACAAH
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCEEEE
WTYGRFRDHQRRLAS
CCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]