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The map label for this gene is hypE [H]

Identifier: 146338766

GI number: 146338766

Start: 1814645

End: 1815685

Strand: Direct

Name: hypE [H]

Synonym: BRADO1700

Alternate gene names: 146338766

Gene position: 1814645-1815685 (Clockwise)

Preceding gene: 146338765

Following gene: 146338767

Centisome position: 24.34

GC content: 66.09

Gene sequence:

>1041_bases
ATGAGCATGCATCAGCGCCGGCTCGACCTGAAGAACGGCTGCGTCGACCTCTCGCACGGCGCCGGTGGCCGCGCGATGGC
GCAGCTGATTGCCGGTCTGTTCCACGAGGCCTTCGGCAACGAATTTCTGGCGCGTGGCAACGATCAGTCCGCCTTCGATG
TCGCGGCCGGGCGGATGGTGATGACGACCGATGGCTATGTCGTGTCGCCGCTGTTTTTTCCCGGCGGCAATATCGGCTCC
CTCGCGGTGCACGGCACGGTCAACGATATCGCCATGGCCGGCGCGAAGCCGCTGTACCTGTCGGCGAGCTTCATCATCGA
GGAGGGCTTCCGCTTCGACGACCTGAAACGAATAGCTGACGCGATGGGGGCGGCGGCACGCGAGGCCGGCATCGCGATTA
TCACGGGCGACACGAAAGTGGTCGAGCGCGGCAAGGCCGATGGCGTCTTCATTTCGACCGCTGGCGTCGGCGTACTGCCT
GACGGGCTCGACCTCTCTGCGGACAAAGCGCGGCCGGGCGATCGCGTGCTGCTATCGGGCAGCCTCGGCGATCACGGCGT
GGCGATCATGTCGAAGCGGCAGAACCTGACCTTCGATACCGAGATCGTCTCCGACTCGGCCTCGCTGCACGGACTCGTCG
CCGCCATGGTCGTAGCCGGCGGCCAGGGCATCCGGCTGATGCGCGATCCGACACGCGGCGGGCTTGCTGCGACGATGAAC
GAGATCGCCCAGCAGTCCAATCTCGGCTTCCGTCTGCAAGAGGAGTCTATTCCAGTGAAGCCGGCCGTGGCCGCTGCCTG
CGAGTTGCTCGGGCTCGATCCGCTGCATGTTGCCAATGAAGGCAAGCTCGTCGCCGTGGTCGCTCCTGACGTCGCCAATG
CCGTGCTCGCGGCGATGAAGGCGCATCCGCTGGGAGGGGAGGCGGCTGACATCGGCGAGGCGGTCGCCGACGATCATCGC
TTCGTCCAGATGGCTACGAGCTTCGGCGGCGGGCGCATCGTCGACTGGCTGTCGGGCGAGCAGTTGCCGCGGATCTGCTG
A

Upstream 100 bases:

>100_bases
CTGAGACGCCGATCGGCTCCTGCATGGTGTCGTCGGAAGGCGCCTGCGCGGCGCATTGGACTTATGGCCGCTTCCGCGAC
CATCAGCGGAGGCTTGCCTC

Downstream 100 bases:

>100_bases
GACGGGTGATGGGAATCCAGGGAACCATATTGGTCGTGGACGACGAGATCCGGTCGCAGGAGGCGCTGCGCCGCGTCCTT
AACCAGGACTTCGAGGTTTT

Product: hydrogenase maturation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSMHQRRLDLKNGCVDLSHGAGGRAMAQLIAGLFHEAFGNEFLARGNDQSAFDVAAGRMVMTTDGYVVSPLFFPGGNIGS
LAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFDDLKRIADAMGAAAREAGIAIITGDTKVVERGKADGVFISTAGVGVLP
DGLDLSADKARPGDRVLLSGSLGDHGVAIMSKRQNLTFDTEIVSDSASLHGLVAAMVVAGGQGIRLMRDPTRGGLAATMN
EIAQQSNLGFRLQEESIPVKPAVAAACELLGLDPLHVANEGKLVAVVAPDVANAVLAAMKAHPLGGEAADIGEAVADDHR
FVQMATSFGGGRIVDWLSGEQLPRIC

Sequences:

>Translated_346_residues
MSMHQRRLDLKNGCVDLSHGAGGRAMAQLIAGLFHEAFGNEFLARGNDQSAFDVAAGRMVMTTDGYVVSPLFFPGGNIGS
LAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFDDLKRIADAMGAAAREAGIAIITGDTKVVERGKADGVFISTAGVGVLP
DGLDLSADKARPGDRVLLSGSLGDHGVAIMSKRQNLTFDTEIVSDSASLHGLVAAMVVAGGQGIRLMRDPTRGGLAATMN
EIAQQSNLGFRLQEESIPVKPAVAAACELLGLDPLHVANEGKLVAVVAPDVANAVLAAMKAHPLGGEAADIGEAVADDHR
FVQMATSFGGGRIVDWLSGEQLPRIC
>Mature_345_residues
SMHQRRLDLKNGCVDLSHGAGGRAMAQLIAGLFHEAFGNEFLARGNDQSAFDVAAGRMVMTTDGYVVSPLFFPGGNIGSL
AVHGTVNDIAMAGAKPLYLSASFIIEEGFRFDDLKRIADAMGAAAREAGIAIITGDTKVVERGKADGVFISTAGVGVLPD
GLDLSADKARPGDRVLLSGSLGDHGVAIMSKRQNLTFDTEIVSDSASLHGLVAAMVVAGGQGIRLMRDPTRGGLAATMNE
IAQQSNLGFRLQEESIPVKPAVAAACELLGLDPLHVANEGKLVAVVAPDVANAVLAAMKAHPLGGEAADIGEAVADDHRF
VQMATSFGGGRIVDWLSGEQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=48.9614243323442, Blast_Score=308, Evalue=3e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35912; Mature: 35780

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMHQRRLDLKNGCVDLSHGAGGRAMAQLIAGLFHEAFGNEFLARGNDQSAFDVAAGRMV
CCCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHCCEEE
MTTDGYVVSPLFFPGGNIGSLAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFDDLKRIAD
EEECCEEEEEEEECCCCCCCEEEECCHHHHHHCCCCCEEEEEEEHHHCCCCHHHHHHHHH
AMGAAAREAGIAIITGDTKVVERGKADGVFISTAGVGVLPDGLDLSADKARPGDRVLLSG
HHHHHHHHCCEEEEECCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEC
SLGDHGVAIMSKRQNLTFDTEIVSDSASLHGLVAAMVVAGGQGIRLMRDPTRGGLAATMN
CCCCCCEEEEECCCCCEEEHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
EIAQQSNLGFRLQEESIPVKPAVAAACELLGLDPLHVANEGKLVAVVAPDVANAVLAAMK
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHHH
AHPLGGEAADIGEAVADDHRFVQMATSFGGGRIVDWLSGEQLPRIC
CCCCCCCHHHHHHHHHCCHHEEEEHHCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
SMHQRRLDLKNGCVDLSHGAGGRAMAQLIAGLFHEAFGNEFLARGNDQSAFDVAAGRMV
CCHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHCCEEE
MTTDGYVVSPLFFPGGNIGSLAVHGTVNDIAMAGAKPLYLSASFIIEEGFRFDDLKRIAD
EEECCEEEEEEEECCCCCCCEEEECCHHHHHHCCCCCEEEEEEEHHHCCCCHHHHHHHHH
AMGAAAREAGIAIITGDTKVVERGKADGVFISTAGVGVLPDGLDLSADKARPGDRVLLSG
HHHHHHHHCCEEEEECCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEC
SLGDHGVAIMSKRQNLTFDTEIVSDSASLHGLVAAMVVAGGQGIRLMRDPTRGGLAATMN
CCCCCCEEEEECCCCCEEEHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
EIAQQSNLGFRLQEESIPVKPAVAAACELLGLDPLHVANEGKLVAVVAPDVANAVLAAMK
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEECCHHHHHHHHHHH
AHPLGGEAADIGEAVADDHRFVQMATSFGGGRIVDWLSGEQLPRIC
CCCCCCCHHHHHHHHHCCHHEEEEHHCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8510650; 7906310; 12597275 [H]