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The map label for this gene is hupN [H]

Identifier: 146338747

GI number: 146338747

Start: 1798094

End: 1799110

Strand: Direct

Name: hupN [H]

Synonym: BRADO1681

Alternate gene names: 146338747

Gene position: 1798094-1799110 (Clockwise)

Preceding gene: 146338746

Following gene: 146338748

Centisome position: 24.11

GC content: 67.75

Gene sequence:

>1017_bases
GTGCTTATGGCCGGCCTCGTGCTCGCCAATGCGCTGGCCTGGGCCTGGGCGTTTCTGCTTTACGCCGATCGCCCGGCCAT
TGTCGGCACCGCGCTGTTGGCCTGGCTGCTCGGCCTGCGGCACGCCGTCGATGCGGACCATATCGCCGCGATCGACAACG
TCGTGCGCAAGCTGGTGCAGGAGGGCGACAGGCCGCGCGCCGCGGGACTCTACTTCGCGCTGGGCCATTCCAGCGTCGTC
GTGATCGCCACGATCGTGGTGAGCCTCGTGGCCGGCGCTGACCTCTTGAGCGAGGACAGCACCATCCGGGCGATCGGCGG
GATCATCGGCACCTCCGTTTCGGCCGGCTTTCTGCTGCTGATTGCCGTCGCCAATCTGGTTCTGTTCCTGAACCTCTGGC
GCTCCCCGTCGGTCCCGCCTGACGGGGAATCGGCCGGCGATGTGGGACGCGGCATCCTGGTTCGGCTGCTGCGTCCGGTG
CTCCGCGTCATCTCGCGCGCCTGGCAGATGTATCCGCTGGGCTTCCTGTTCGGTCTCGGCTTCGACACCGCCAGCGAGAT
CGGACTGCTCAGCCTGTCGGCGACAGAGGCGGCGCGCGGCGCGAGCCTGGCCCATGTGCTGGTGTTCCCGGCGCTGTTCG
CAGCAGCGATGGCGACCGTCGATACCGCCGACAGCATGCTGATGGTCGGCGCCTATCGCTGGGCGCTCACCGATCCTGCC
CGCAAGCGGCGCTATAATCTCGTGATCACAGGAGCCTCCGTCGCAATCGCGCTGGTGATCGGCGGCGTAGAGGCGGTCAC
GCTGCTGGCGCCGCGGCTGGGTCTGACCGGCGGATGGAACGATGTCGTGGCGGCGTTGGGCGACGATCTCGGCTATCTCG
GCATCATCGCCATCGGGCTGTTTGGCCTGACCTGGGCCGGCGCCGTGCTGATCAGCCGCTGCCGCGGCACCTCACATGCA
TCAGTCGAGGCGCTTGCCAGTGTTCGCGCCAGGACGCTAAACCCGACGGCGAAATAA

Upstream 100 bases:

>100_bases
CTTGCTCTCCTGTCCGAGTATGACGATTTTGCCAATTGATCATCCTCGGCCGGCCGCCTCGATCCCGGTTCGGCTCCGCG
GGGACGGCGCACGAAATGCC

Downstream 100 bases:

>100_bases
GGCGGAACGCACGGGACGGAGCGACCCACGATGGCCGGCGCGGAGGGCGGGATCAGGATGCTGTGGTTGCAGGGCGCGAG
TTGCGGCGGCTGCACCATGT

Product: hydrogenase nickel incorporation protein hupN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLMAGLVLANALAWAWAFLLYADRPAIVGTALLAWLLGLRHAVDADHIAAIDNVVRKLVQEGDRPRAAGLYFALGHSSVV
VIATIVVSLVAGADLLSEDSTIRAIGGIIGTSVSAGFLLLIAVANLVLFLNLWRSPSVPPDGESAGDVGRGILVRLLRPV
LRVISRAWQMYPLGFLFGLGFDTASEIGLLSLSATEAARGASLAHVLVFPALFAAAMATVDTADSMLMVGAYRWALTDPA
RKRRYNLVITGASVAIALVIGGVEAVTLLAPRLGLTGGWNDVVAALGDDLGYLGIIAIGLFGLTWAGAVLISRCRGTSHA
SVEALASVRARTLNPTAK

Sequences:

>Translated_338_residues
MLMAGLVLANALAWAWAFLLYADRPAIVGTALLAWLLGLRHAVDADHIAAIDNVVRKLVQEGDRPRAAGLYFALGHSSVV
VIATIVVSLVAGADLLSEDSTIRAIGGIIGTSVSAGFLLLIAVANLVLFLNLWRSPSVPPDGESAGDVGRGILVRLLRPV
LRVISRAWQMYPLGFLFGLGFDTASEIGLLSLSATEAARGASLAHVLVFPALFAAAMATVDTADSMLMVGAYRWALTDPA
RKRRYNLVITGASVAIALVIGGVEAVTLLAPRLGLTGGWNDVVAALGDDLGYLGIIAIGLFGLTWAGAVLISRCRGTSHA
SVEALASVRARTLNPTAK
>Mature_338_residues
MLMAGLVLANALAWAWAFLLYADRPAIVGTALLAWLLGLRHAVDADHIAAIDNVVRKLVQEGDRPRAAGLYFALGHSSVV
VIATIVVSLVAGADLLSEDSTIRAIGGIIGTSVSAGFLLLIAVANLVLFLNLWRSPSVPPDGESAGDVGRGILVRLLRPV
LRVISRAWQMYPLGFLFGLGFDTASEIGLLSLSATEAARGASLAHVLVFPALFAAAMATVDTADSMLMVGAYRWALTDPA
RKRRYNLVITGASVAIALVIGGVEAVTLLAPRLGLTGGWNDVVAALGDDLGYLGIIAIGLFGLTWAGAVLISRCRGTSHA
SVEALASVRARTLNPTAK

Specific function: Involved in nickel incorporation/metabolism into the hydrogenase apoprotein [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 35222; Mature: 35222

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMAGLVLANALAWAWAFLLYADRPAIVGTALLAWLLGLRHAVDADHIAAIDNVVRKLVQ
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EGDRPRAAGLYFALGHSSVVVIATIVVSLVAGADLLSEDSTIRAIGGIIGTSVSAGFLLL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
IAVANLVLFLNLWRSPSVPPDGESAGDVGRGILVRLLRPVLRVISRAWQMYPLGFLFGLG
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FDTASEIGLLSLSATEAARGASLAHVLVFPALFAAAMATVDTADSMLMVGAYRWALTDPA
CCCHHHCCEEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RKRRYNLVITGASVAIALVIGGVEAVTLLAPRLGLTGGWNDVVAALGDDLGYLGIIAIGL
HHCEEEEEEECHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHH
FGLTWAGAVLISRCRGTSHASVEALASVRARTLNPTAK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLMAGLVLANALAWAWAFLLYADRPAIVGTALLAWLLGLRHAVDADHIAAIDNVVRKLVQ
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
EGDRPRAAGLYFALGHSSVVVIATIVVSLVAGADLLSEDSTIRAIGGIIGTSVSAGFLLL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
IAVANLVLFLNLWRSPSVPPDGESAGDVGRGILVRLLRPVLRVISRAWQMYPLGFLFGLG
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FDTASEIGLLSLSATEAARGASLAHVLVFPALFAAAMATVDTADSMLMVGAYRWALTDPA
CCCHHHCCEEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RKRRYNLVITGASVAIALVIGGVEAVTLLAPRLGLTGGWNDVVAALGDDLGYLGIIAIGL
HHCEEEEEEECHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHH
FGLTWAGAVLISRCRGTSHASVEALASVRARTLNPTAK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8197192; 12597275 [H]