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The map label for this gene is cbbF

Identifier: 146338722

GI number: 146338722

Start: 1772435

End: 1773505

Strand: Direct

Name: cbbF

Synonym: BRADO1655

Alternate gene names: 146338722

Gene position: 1772435-1773505 (Clockwise)

Preceding gene: 146338720

Following gene: 146338723

Centisome position: 23.77

GC content: 67.51

Gene sequence:

>1071_bases
ATGGCGAGGGAGTGGCCCATGACTCATCCGTCCAATCACCCGATGGATCATCATCATCAGACACTGCAGGCCCATCTGGC
ATCCCAAGGGGCGGATGCCGATTGTGCCGCGGTCATCGAAGCCCTCGCCGACGCCGCGCGCGAGCTCGCGCGGCAGATCG
CCATCGCGCCGCTGTCCGGCATCGACGAAGGCGCGGCGACCGTCAACACCGACGGCGATATCCAGAAGGCGCTCGATATC
GTCGCCGACAATCTGATGCGCGAGGCCCTGCGCCGCGCGCCGGTCGCCGGCATCCTGTCGGAAGAGGGCGATCGGCCGGA
AACGGTCAATGAGGCTGCCCCACTTTGCGTGGCGATCGATCCGCTCGACGGCTCATCCAACCTTCAGAACAATATCTCGG
TCGGCACCATCTTCTCGATCCGGCCGCGCGGCCGCGACGTGCTCTCCAGTTTCTTCGAGCCCGGCACCGCGCAGCGTGCC
GCCGGCTTCTTCGTCTACGGCCCGCAGACCTGCCTCGTGCTGGCAATCGACCGTCGAGTCGACCTCTACGTCCTGCACCC
GACGCTGCACGAGTTCATTCTGGCCAAGTCCGGCATCCGCATTCCGCAGGACACGCCGGAGTTCGCGATCAACGCCTCCA
ACCGCCGGCACTGGAGCGGCGCGGTCCGCAACTATGTCGACGAGTGCCTGTCGGGCGCCGCCGGCCCTCGCGGCCGCGAC
TTCAACATGCGCTGGATCGCCTCGCTGGTGGCGGAAGCCTATCGCATCCTGATGCGCGGCGGTGTGTTTCTGTATCCCGC
CGATTCCAGGCCGGGCTATCGCGAGGGCCGGCTGCGGCTGGTGTACGAGGCGCACCCGATGGCGCTGATCATGGAATGGG
CCGGCGGCTCCGCCTCGAGCGGCCGCGCCCGCATCCTCGAATTGTCGGCGCGCTCGCCGCATCAGCGGGCGCCCCTGATC
ATGGGCGATGTCCGTCTCGTACGGGATGTCGACATGCTGCACGAGGGCGTCGAGCCGCTGTTCGAAACCAGCGATGCGCC
CCTGTTCGCCCGCCGCGGCCTGTTCCGCTGA

Upstream 100 bases:

>100_bases
AAAGATATTGAAATTTCCCTAATCACGCAAATCGAGTGTTGATAGCAGCGCGGCACGACGCATTCGTGCGGCTTCATCAA
AGTTCCCGGCAGAGGAGCTG

Downstream 100 bases:

>100_bases
GCGCGCTGTCGAGCCGGCACCGCTCGGCGAGACTTCCGGAGATATAGTCATGTCACGTCGTCATCCCATCATTTCGATCA
CGGGCTCGTCGGGCGCCGGC

Product: D-fructose-1,6-bisphosphatase protein

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MAREWPMTHPSNHPMDHHHQTLQAHLASQGADADCAAVIEALADAARELARQIAIAPLSGIDEGAATVNTDGDIQKALDI
VADNLMREALRRAPVAGILSEEGDRPETVNEAAPLCVAIDPLDGSSNLQNNISVGTIFSIRPRGRDVLSSFFEPGTAQRA
AGFFVYGPQTCLVLAIDRRVDLYVLHPTLHEFILAKSGIRIPQDTPEFAINASNRRHWSGAVRNYVDECLSGAAGPRGRD
FNMRWIASLVAEAYRILMRGGVFLYPADSRPGYREGRLRLVYEAHPMALIMEWAGGSASSGRARILELSARSPHQRAPLI
MGDVRLVRDVDMLHEGVEPLFETSDAPLFARRGLFR

Sequences:

>Translated_356_residues
MAREWPMTHPSNHPMDHHHQTLQAHLASQGADADCAAVIEALADAARELARQIAIAPLSGIDEGAATVNTDGDIQKALDI
VADNLMREALRRAPVAGILSEEGDRPETVNEAAPLCVAIDPLDGSSNLQNNISVGTIFSIRPRGRDVLSSFFEPGTAQRA
AGFFVYGPQTCLVLAIDRRVDLYVLHPTLHEFILAKSGIRIPQDTPEFAINASNRRHWSGAVRNYVDECLSGAAGPRGRD
FNMRWIASLVAEAYRILMRGGVFLYPADSRPGYREGRLRLVYEAHPMALIMEWAGGSASSGRARILELSARSPHQRAPLI
MGDVRLVRDVDMLHEGVEPLFETSDAPLFARRGLFR
>Mature_355_residues
AREWPMTHPSNHPMDHHHQTLQAHLASQGADADCAAVIEALADAARELARQIAIAPLSGIDEGAATVNTDGDIQKALDIV
ADNLMREALRRAPVAGILSEEGDRPETVNEAAPLCVAIDPLDGSSNLQNNISVGTIFSIRPRGRDVLSSFFEPGTAQRAA
GFFVYGPQTCLVLAIDRRVDLYVLHPTLHEFILAKSGIRIPQDTPEFAINASNRRHWSGAVRNYVDECLSGAAGPRGRDF
NMRWIASLVAEAYRILMRGGVFLYPADSRPGYREGRLRLVYEAHPMALIMEWAGGSASSGRARILELSARSPHQRAPLIM
GDVRLVRDVDMLHEGVEPLFETSDAPLFARRGLFR

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=328, Percent_Identity=33.8414634146341, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI16579888, Length=328, Percent_Identity=33.8414634146341, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI22907028, Length=328, Percent_Identity=30.4878048780488, Blast_Score=152, Evalue=7e-37,
Organism=Escherichia coli, GI1790679, Length=309, Percent_Identity=37.5404530744337, Blast_Score=193, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17508131, Length=332, Percent_Identity=32.5301204819277, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6323409, Length=300, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=4e-42,
Organism=Drosophila melanogaster, GI45550998, Length=312, Percent_Identity=30.7692307692308, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI19921562, Length=312, Percent_Identity=30.7692307692308, Blast_Score=154, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_BRASO (A4YNQ7)

Other databases:

- EMBL:   CU234118
- RefSeq:   YP_001203770.1
- STRING:   A4YNQ7
- GeneID:   5115888
- GenomeReviews:   CU234118_GR
- KEGG:   bra:BRADO1655
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   YSINEGS
- ProtClustDB:   CLSK855532
- BioCyc:   BSP376:BRADO1655-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 39011; Mature: 38880

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00124 FBPASE

Important sites: BINDING 211-211

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREWPMTHPSNHPMDHHHQTLQAHLASQGADADCAAVIEALADAARELARQIAIAPLSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
IDEGAATVNTDGDIQKALDIVADNLMREALRRAPVAGILSEEGDRPETVNEAAPLCVAID
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHCCCCEEEEEE
PLDGSSNLQNNISVGTIFSIRPRGRDVLSSFFEPGTAQRAAGFFVYGPQTCLVLAIDRRV
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCHHHCCEEEECCCEEEEEEEECCC
DLYVLHPTLHEFILAKSGIRIPQDTPEFAINASNRRHWSGAVRNYVDECLSGAAGPRGRD
EEEEECHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
FNMRWIASLVAEAYRILMRGGVFLYPADSRPGYREGRLRLVYEAHPMALIMEWAGGSASS
CCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCC
GRARILELSARSPHQRAPLIMGDVRLVRDVDMLHEGVEPLFETSDAPLFARRGLFR
CCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
>Mature Secondary Structure 
AREWPMTHPSNHPMDHHHQTLQAHLASQGADADCAAVIEALADAARELARQIAIAPLSG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
IDEGAATVNTDGDIQKALDIVADNLMREALRRAPVAGILSEEGDRPETVNEAAPLCVAID
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHCCCCEEEEEE
PLDGSSNLQNNISVGTIFSIRPRGRDVLSSFFEPGTAQRAAGFFVYGPQTCLVLAIDRRV
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCCHHHCCEEEECCCEEEEEEEECCC
DLYVLHPTLHEFILAKSGIRIPQDTPEFAINASNRRHWSGAVRNYVDECLSGAAGPRGRD
EEEEECHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
FNMRWIASLVAEAYRILMRGGVFLYPADSRPGYREGRLRLVYEAHPMALIMEWAGGSASS
CCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEEECCCCCCC
GRARILELSARSPHQRAPLIMGDVRLVRDVDMLHEGVEPLFETSDAPLFARRGLFR
CCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA