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The map label for this gene is hmuO [H]

Identifier: 146338694

GI number: 146338694

Start: 1739894

End: 1740577

Strand: Direct

Name: hmuO [H]

Synonym: BRADO1626

Alternate gene names: 146338694

Gene position: 1739894-1740577 (Clockwise)

Preceding gene: 146338693

Following gene: 146338698

Centisome position: 23.33

GC content: 66.96

Gene sequence:

>684_bases
ATGTTGGACCGAGTTGATTCCAATCACGTCGAAACGGCCGGGCGCACCACGCGTCCGGCCGGTCTTTTGGAAGCCATGCG
CGAGCGGACCAAGACGCTGCACGTGACGGCGGAGCGGACCGGCGTCGTCGCCGAGCTGTTGCGCGGCCGCGGCACGGTGC
GCGCCTATGCGCTGCTGCTGCGCAATCTGCTGCCGGTCTATGAGGCGCTCGAAGCGGAGCTCGTTCGTCATCAGGCGTCA
CCGGTGGTCGGACTGACGGTGCGGCCGGAGCTGCATCGGTGTCCAGCGATCAAGGCCGATCTCGCCGCGCTCGACGCGAG
CGATCTGCCGTTGCTGCCCGAGGCCATCGCCTATGTTCGCGCCATCCAGGAGGCGGGATCCGGCTCCGGTCATCCGCTGC
TGGCGCACGCCTATACACGCTATCTCGGTGATCTCAGCGGCGGCCAGATCATCAAGAAGATCCTCGCCCGCTCGCTCGAA
CTGCAGCCCGAGGCGCTGTCGTTCTACGAGTTTCCGGCGATCACCGACATTCCGCGCTTCAAGACCGAGTACCGCGAGGC
GCTGGAGCAGGCCGGCTCGGCGATGACAGAGCATGACTCCGTCGTCGAGGAAGCGGCCACGGCTTTCCAGCTGAACATCA
CGCTGTCGCAGGCGCTGCAGTCGGCCGCGGGGCTCGGCCGCTGA

Upstream 100 bases:

>100_bases
CATCGGTATCCTACTGTCGGGCACCGTCGTCGACAATTGGTTCGACTGGGGCGTGAAACACGGGCTGGCGCCGCCGCGCT
GAAGCTCTGCGGGTTGAGAG

Downstream 100 bases:

>100_bases
AAGTTGGCCGCGTCCTCTGGACGCGCTGTTTCTTGGCTCGCATGATAGCTCGGATCCTAGCTACCGCGCTCGACCAGAGC
GGTAGAGCTTGTGAGCCAAT

Product: heme oxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MLDRVDSNHVETAGRTTRPAGLLEAMRERTKTLHVTAERTGVVAELLRGRGTVRAYALLLRNLLPVYEALEAELVRHQAS
PVVGLTVRPELHRCPAIKADLAALDASDLPLLPEAIAYVRAIQEAGSGSGHPLLAHAYTRYLGDLSGGQIIKKILARSLE
LQPEALSFYEFPAITDIPRFKTEYREALEQAGSAMTEHDSVVEEAATAFQLNITLSQALQSAAGLGR

Sequences:

>Translated_227_residues
MLDRVDSNHVETAGRTTRPAGLLEAMRERTKTLHVTAERTGVVAELLRGRGTVRAYALLLRNLLPVYEALEAELVRHQAS
PVVGLTVRPELHRCPAIKADLAALDASDLPLLPEAIAYVRAIQEAGSGSGHPLLAHAYTRYLGDLSGGQIIKKILARSLE
LQPEALSFYEFPAITDIPRFKTEYREALEQAGSAMTEHDSVVEEAATAFQLNITLSQALQSAAGLGR
>Mature_227_residues
MLDRVDSNHVETAGRTTRPAGLLEAMRERTKTLHVTAERTGVVAELLRGRGTVRAYALLLRNLLPVYEALEAELVRHQAS
PVVGLTVRPELHRCPAIKADLAALDASDLPLLPEAIAYVRAIQEAGSGSGHPLLAHAYTRYLGDLSGGQIIKKILARSLE
LQPEALSFYEFPAITDIPRFKTEYREALEQAGSAMTEHDSVVEEAATAFQLNITLSQALQSAAGLGR

Specific function: Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennas. Upon overexpression in E.coli with PCB:ferredoxin oxidoreductase, CpeS and either CpcB or PecB permits sy

COG id: COG5398

COG function: function code P; Heme oxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4504437, Length=209, Percent_Identity=39.2344497607655, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI187761311, Length=231, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI187761309, Length=231, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI187761307, Length=231, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI8051608, Length=231, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002051
- InterPro:   IPR016053
- InterPro:   IPR016084
- InterPro:   IPR018207 [H]

Pfam domain/function: PF01126 Heme_oxygenase [H]

EC number: =1.14.99.3 [H]

Molecular weight: Translated: 24657; Mature: 24657

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRVDSNHVETAGRTTRPAGLLEAMRERTKTLHVTAERTGVVAELLRGRGTVRAYALLL
CCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCHHHHHHHHH
RNLLPVYEALEAELVRHQASPVVGLTVRPELHRCPAIKADLAALDASDLPLLPEAIAYVR
HHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHH
AIQEAGSGSGHPLLAHAYTRYLGDLSGGQIIKKILARSLELQPEALSFYEFPAITDIPRF
HHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHH
KTEYREALEQAGSAMTEHDSVVEEAATAFQLNITLSQALQSAAGLGR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDRVDSNHVETAGRTTRPAGLLEAMRERTKTLHVTAERTGVVAELLRGRGTVRAYALLL
CCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHCCCHHHHHHHHH
RNLLPVYEALEAELVRHQASPVVGLTVRPELHRCPAIKADLAALDASDLPLLPEAIAYVR
HHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHH
AIQEAGSGSGHPLLAHAYTRYLGDLSGGQIIKKILARSLELQPEALSFYEFPAITDIPRF
HHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHH
KTEYREALEQAGSAMTEHDSVVEEAATAFQLNITLSQALQSAAGLGR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]