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The map label for this gene is cutL [H]

Identifier: 146338488

GI number: 146338488

Start: 1503758

End: 1506091

Strand: Direct

Name: cutL [H]

Synonym: BRADO1406

Alternate gene names: 146338488

Gene position: 1503758-1506091 (Clockwise)

Preceding gene: 146338487

Following gene: 146338491

Centisome position: 20.17

GC content: 67.69

Gene sequence:

>2334_bases
ATGAACATTCTTCCCAACAATATGCGGTTCGGTGCAGGGCAGCCGGTCAAGCGGCTGGAGGATCAGCGGCTGCTGACCGG
GAAGGGGCAGTTCATCGACGACAAGCCTGAGGATGGCGCGCTGTGGCTCACCGTGCTGCGCTCGCCGCATGCCCATGCCA
AAATTCTCTCGATCGACACCGCCGCCGCGCGCGAGATCCCGGGGGTCGAGGCGATCTACACCGGGGCGGACCTCGTCGCG
GACGATGTCGGCACCATTCCGACGCTGGCGATCTTCAAGCGCCCCGACGGCAAGCCGATGACGGTGCCGCCACGCCGGCT
GCTGGCCCATGATGTCGTCCGCTTCACCGGCGAGGCGGTGGCCGCCGTGGTCGCCACCTCGCGCGCGATCGCGCAGGAGG
CCGCGGAAGCGATTGTTGTCGACTACGAGGTGCTGCCGGCGGTGACCGATCCGGTCAAGGCGCTCGAGCCCGGCGCGCCG
GTGGTGTGGGCCGAGGCGCCCGACAATATCGTGGCGGCGATGAGCTATGGCGATGCCGCCAAGGTCGAGGAGGCCTTCGC
CAGCGCGCCGCACAAGGTGTCGCTCGATATCGTGAGCCAGCGCCTGGTGCCCTCGGCGATGGAGCCGCGCTCGACCATCG
CCGAGATCGAGAAGAAGACCGGACGTCTCCTCTTGTACGTGCAGTCGCAGACGCCGGCATCGACCCGCGACGTGCTGGCC
GACGCCGTGTTGAAGCGGCCGAAGGACAGCATCCGCGTGCTGGTCGGCGACATCGGCGGCGGTTTCGGCCAGAAGACCAA
CCTCTATCCCGAGGATGGCATCGTCGCCTATGCCGCGACCAAGCTCGCCAAGAAGATCCGCTGGCGTGCCGAGCGCACCG
ACGAGTTCGTCGGCGGCACCCATGGCCGCGACCTCACCTCGACCGCGGAGTTCGCGCTGGATGCCAAGGGCAAGGTGCTG
GCCTATCGCGTGCGCTCGATCGGCGCCACCGGGGCTTATTCCTCCGGCGCGGCCAACATCATCCCGCTGGTGCTCGGGCC
GTTCGTGCAGACCGGCGTCTACGACCTGCCGCTGGTGCATTTCGAGATCAAGACCGTCATGACGCATACGGCGCCGGTCG
GCGCCTATCGCGGCGCCGGTCGTCCCGAGGCGGTCTTCATCGTCGAGCGCCTGTTCGACACTGCTGCGCGCCAGATCGGC
ATCGATCCGCGCACCATCCGGAAAGCCAACTACATCAAGCCGGCGCAACTGCCCTACACCAACGCCGTCGGCCAGGTGTA
TGATTCCGGCGCCTTCGCCCACATGCTGGAGCGCGCCGCCAAGCTCGCGGACTGGGACGGCTTCAACGCGCGCAAGCGCG
AAGCGAAGAAGCGCGGCATGCTCTATGGCCGCGGTCTCACCTCTTACATCGAATGGACCGGCGGCCGCGCCCACACCGAG
AAGGTCTCGCTGCACGCGACGTCGGAAGGGCGCGTCATCCTGCATTCCGGCACGATGGCGATGGGGCAGGGGCTGCAGAC
CACCTACACGCAGATGATCTCCGACACGCTGGGCATCCCGCTCGACAAGATCGACGTCGTGCAGGGCGATACCGATCTGG
CCACCGGCTTCGGCAGCGTCGGCTCGCGCTCGCTGTTCGTCGGCGGCACGGCGGTGGCGGTGTCGTCGAACGACCTGATC
ACCAAGGCCCGGGAAAAGGCGTCGAACCTGCTGGAGACCGCGGTCGAGGACATCGAGTATCGCGACGGTGTGCTGTCGGT
GGTCGGTACCGACCGCCGCATCAGCCTGTTCGAGATCGCGCAGAAGGAGCAGGCCGCCAAGCTGTCGGTCGACAGCGAGG
GCGAGGTCGACGGTCCGAGCTGGCCGAACGGCACGCACATCTGCGAGGTCGAGATCGATCCGGAGACCGGCATCAGCCGC
GTCGTGCGCTATACCACGGTCGACGACGTCGGCGTCGCAGTGAACCCGATGCTGGTGGCCGGCCAGATCCACGGCGGCGT
CGCCCAGGGCATCGGCCAGGCGCTGTATGAGAACGTCGCCTACGATGCCGACGGCCAGCTGCTGACCGCGACCTATCAGG
ACTACTGCATCCCGCGCGCCGACGACGTGCCGCCGATCGCGGTCACGCTCGACGATTCCGCCCCCTGCAAGACCAACCCG
CTCGGCGCCAAGGGCTGCGGCGAATCCGGCGCCATCGGCGGCCCGCCCTGCGTCACCAACGGCGTCATGGACGCGCTGTT
CGAACTGGGCATCACCAATTTGCAGACCCCGCTGACGCCGGAGAAGGTGTGGGCCGCGATTCGGGATGCGAAGGCGAAGA
AGGCGGCGGCGTAG

Upstream 100 bases:

>100_bases
ACGATGCGGTATGACGCACCGGCACAATCACGGCTTGGCCAGCGCGACGGCGATCCGCTAAACAGCATGCAATTACATTG
AACTCACCAAGGATTCCCGA

Downstream 100 bases:

>100_bases
GTCCGCAGAACAGAGGCTCTTTTCAGCCCCCTCTTGGATCCGAGCCCTTACCACAAGCACGCTGCGCCCCCCTCCCCCTT
GCGGGGAGGGGGTCGGGGGT

Product: putative dehydrogenase/oxidase/molybdopterin binding protein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MNILPNNMRFGAGQPVKRLEDQRLLTGKGQFIDDKPEDGALWLTVLRSPHAHAKILSIDTAAAREIPGVEAIYTGADLVA
DDVGTIPTLAIFKRPDGKPMTVPPRRLLAHDVVRFTGEAVAAVVATSRAIAQEAAEAIVVDYEVLPAVTDPVKALEPGAP
VVWAEAPDNIVAAMSYGDAAKVEEAFASAPHKVSLDIVSQRLVPSAMEPRSTIAEIEKKTGRLLLYVQSQTPASTRDVLA
DAVLKRPKDSIRVLVGDIGGGFGQKTNLYPEDGIVAYAATKLAKKIRWRAERTDEFVGGTHGRDLTSTAEFALDAKGKVL
AYRVRSIGATGAYSSGAANIIPLVLGPFVQTGVYDLPLVHFEIKTVMTHTAPVGAYRGAGRPEAVFIVERLFDTAARQIG
IDPRTIRKANYIKPAQLPYTNAVGQVYDSGAFAHMLERAAKLADWDGFNARKREAKKRGMLYGRGLTSYIEWTGGRAHTE
KVSLHATSEGRVILHSGTMAMGQGLQTTYTQMISDTLGIPLDKIDVVQGDTDLATGFGSVGSRSLFVGGTAVAVSSNDLI
TKAREKASNLLETAVEDIEYRDGVLSVVGTDRRISLFEIAQKEQAAKLSVDSEGEVDGPSWPNGTHICEVEIDPETGISR
VVRYTTVDDVGVAVNPMLVAGQIHGGVAQGIGQALYENVAYDADGQLLTATYQDYCIPRADDVPPIAVTLDDSAPCKTNP
LGAKGCGESGAIGGPPCVTNGVMDALFELGITNLQTPLTPEKVWAAIRDAKAKKAAA

Sequences:

>Translated_777_residues
MNILPNNMRFGAGQPVKRLEDQRLLTGKGQFIDDKPEDGALWLTVLRSPHAHAKILSIDTAAAREIPGVEAIYTGADLVA
DDVGTIPTLAIFKRPDGKPMTVPPRRLLAHDVVRFTGEAVAAVVATSRAIAQEAAEAIVVDYEVLPAVTDPVKALEPGAP
VVWAEAPDNIVAAMSYGDAAKVEEAFASAPHKVSLDIVSQRLVPSAMEPRSTIAEIEKKTGRLLLYVQSQTPASTRDVLA
DAVLKRPKDSIRVLVGDIGGGFGQKTNLYPEDGIVAYAATKLAKKIRWRAERTDEFVGGTHGRDLTSTAEFALDAKGKVL
AYRVRSIGATGAYSSGAANIIPLVLGPFVQTGVYDLPLVHFEIKTVMTHTAPVGAYRGAGRPEAVFIVERLFDTAARQIG
IDPRTIRKANYIKPAQLPYTNAVGQVYDSGAFAHMLERAAKLADWDGFNARKREAKKRGMLYGRGLTSYIEWTGGRAHTE
KVSLHATSEGRVILHSGTMAMGQGLQTTYTQMISDTLGIPLDKIDVVQGDTDLATGFGSVGSRSLFVGGTAVAVSSNDLI
TKAREKASNLLETAVEDIEYRDGVLSVVGTDRRISLFEIAQKEQAAKLSVDSEGEVDGPSWPNGTHICEVEIDPETGISR
VVRYTTVDDVGVAVNPMLVAGQIHGGVAQGIGQALYENVAYDADGQLLTATYQDYCIPRADDVPPIAVTLDDSAPCKTNP
LGAKGCGESGAIGGPPCVTNGVMDALFELGITNLQTPLTPEKVWAAIRDAKAKKAAA
>Mature_777_residues
MNILPNNMRFGAGQPVKRLEDQRLLTGKGQFIDDKPEDGALWLTVLRSPHAHAKILSIDTAAAREIPGVEAIYTGADLVA
DDVGTIPTLAIFKRPDGKPMTVPPRRLLAHDVVRFTGEAVAAVVATSRAIAQEAAEAIVVDYEVLPAVTDPVKALEPGAP
VVWAEAPDNIVAAMSYGDAAKVEEAFASAPHKVSLDIVSQRLVPSAMEPRSTIAEIEKKTGRLLLYVQSQTPASTRDVLA
DAVLKRPKDSIRVLVGDIGGGFGQKTNLYPEDGIVAYAATKLAKKIRWRAERTDEFVGGTHGRDLTSTAEFALDAKGKVL
AYRVRSIGATGAYSSGAANIIPLVLGPFVQTGVYDLPLVHFEIKTVMTHTAPVGAYRGAGRPEAVFIVERLFDTAARQIG
IDPRTIRKANYIKPAQLPYTNAVGQVYDSGAFAHMLERAAKLADWDGFNARKREAKKRGMLYGRGLTSYIEWTGGRAHTE
KVSLHATSEGRVILHSGTMAMGQGLQTTYTQMISDTLGIPLDKIDVVQGDTDLATGFGSVGSRSLFVGGTAVAVSSNDLI
TKAREKASNLLETAVEDIEYRDGVLSVVGTDRRISLFEIAQKEQAAKLSVDSEGEVDGPSWPNGTHICEVEIDPETGISR
VVRYTTVDDVGVAVNPMLVAGQIHGGVAQGIGQALYENVAYDADGQLLTATYQDYCIPRADDVPPIAVTLDDSAPCKTNP
LGAKGCGESGAIGGPPCVTNGVMDALFELGITNLQTPLTPEKVWAAIRDAKAKKAAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=801, Percent_Identity=26.4669163545568, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI91823271, Length=800, Percent_Identity=26, Blast_Score=169, Evalue=8e-42,
Organism=Escherichia coli, GI1789246, Length=817, Percent_Identity=27.0501835985312, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1789230, Length=767, Percent_Identity=27.9009126466754, Blast_Score=209, Evalue=7e-55,
Organism=Escherichia coli, GI1786478, Length=786, Percent_Identity=24.5547073791349, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=799, Percent_Identity=26.4080100125156, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17539860, Length=787, Percent_Identity=24.3964421855146, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32566215, Length=704, Percent_Identity=24.1477272727273, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24647199, Length=750, Percent_Identity=26, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24647193, Length=732, Percent_Identity=24.7267759562842, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI17737937, Length=746, Percent_Identity=24.9329758713137, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647195, Length=776, Percent_Identity=24.2268041237113, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24647201, Length=761, Percent_Identity=23.915900131406, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24647197, Length=736, Percent_Identity=24.4565217391304, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82780; Mature: 82780

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILPNNMRFGAGQPVKRLEDQRLLTGKGQFIDDKPEDGALWLTVLRSPHAHAKILSIDT
CCCCCCCCCCCCCCCHHHHCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECH
AAAREIPGVEAIYTGADLVADDVGTIPTLAIFKRPDGKPMTVPPRRLLAHDVVRFTGEAV
HHHHCCCCCEEEECCCHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AAVVATSRAIAQEAAEAIVVDYEVLPAVTDPVKALEPGAPVVWAEAPDNIVAAMSYGDAA
HHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCHHHCCCCCCEEEECCCCCEEEEECCCCHH
KVEEAFASAPHKVSLDIVSQRLVPSAMEPRSTIAEIEKKTGRLLLYVQSQTPASTRDVLA
HHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
DAVLKRPKDSIRVLVGDIGGGFGQKTNLYPEDGIVAYAATKLAKKIRWRAERTDEFVGGT
HHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCC
HGRDLTSTAEFALDAKGKVLAYRVRSIGATGAYSSGAANIIPLVLGPFVQTGVYDLPLVH
CCCCCCCHHHHEECCCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEE
FEIKTVMTHTAPVGAYRGAGRPEAVFIVERLFDTAARQIGIDPRTIRKANYIKPAQLPYT
EEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCC
NAVGQVYDSGAFAHMLERAAKLADWDGFNARKREAKKRGMLYGRGLTSYIEWTGGRAHTE
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCHHHHHEECCCCCCCE
KVSLHATSEGRVILHSGTMAMGQGLQTTYTQMISDTLGIPLDKIDVVQGDTDLATGFGSV
EEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCC
GSRSLFVGGTAVAVSSNDLITKAREKASNLLETAVEDIEYRDGVLSVVGTDRRISLFEIA
CCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
QKEQAAKLSVDSEGEVDGPSWPNGTHICEVEIDPETGISRVVRYTTVDDVGVAVNPMLVA
HHHHHHEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHEEEEEECCCCCEECCEEEE
GQIHGGVAQGIGQALYENVAYDADGQLLTATYQDYCIPRADDVPPIAVTLDDSAPCKTNP
EECCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCCCCCEEEEECCCCCCCCCC
LGAKGCGESGAIGGPPCVTNGVMDALFELGITNLQTPLTPEKVWAAIRDAKAKKAAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNILPNNMRFGAGQPVKRLEDQRLLTGKGQFIDDKPEDGALWLTVLRSPHAHAKILSIDT
CCCCCCCCCCCCCCCHHHHCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECH
AAAREIPGVEAIYTGADLVADDVGTIPTLAIFKRPDGKPMTVPPRRLLAHDVVRFTGEAV
HHHHCCCCCEEEECCCHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AAVVATSRAIAQEAAEAIVVDYEVLPAVTDPVKALEPGAPVVWAEAPDNIVAAMSYGDAA
HHHHHHHHHHHHHHHHEEEEEHHHHCCCCCCHHHCCCCCCEEEECCCCCEEEEECCCCHH
KVEEAFASAPHKVSLDIVSQRLVPSAMEPRSTIAEIEKKTGRLLLYVQSQTPASTRDVLA
HHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
DAVLKRPKDSIRVLVGDIGGGFGQKTNLYPEDGIVAYAATKLAKKIRWRAERTDEFVGGT
HHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCC
HGRDLTSTAEFALDAKGKVLAYRVRSIGATGAYSSGAANIIPLVLGPFVQTGVYDLPLVH
CCCCCCCHHHHEECCCCCEEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEE
FEIKTVMTHTAPVGAYRGAGRPEAVFIVERLFDTAARQIGIDPRTIRKANYIKPAQLPYT
EEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCC
NAVGQVYDSGAFAHMLERAAKLADWDGFNARKREAKKRGMLYGRGLTSYIEWTGGRAHTE
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEECCHHHHHEECCCCCCCE
KVSLHATSEGRVILHSGTMAMGQGLQTTYTQMISDTLGIPLDKIDVVQGDTDLATGFGSV
EEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHCCCCC
GSRSLFVGGTAVAVSSNDLITKAREKASNLLETAVEDIEYRDGVLSVVGTDRRISLFEIA
CCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
QKEQAAKLSVDSEGEVDGPSWPNGTHICEVEIDPETGISRVVRYTTVDDVGVAVNPMLVA
HHHHHHEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHEEEEEECCCCCEECCEEEE
GQIHGGVAQGIGQALYENVAYDADGQLLTATYQDYCIPRADDVPPIAVTLDDSAPCKTNP
EECCCHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCCCCCEEEEECCCCCCCCCC
LGAKGCGESGAIGGPPCVTNGVMDALFELGITNLQTPLTPEKVWAAIRDAKAKKAAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]