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The map label for this gene is srpA [H]

Identifier: 146338463

GI number: 146338463

Start: 1467668

End: 1468612

Strand: Direct

Name: srpA [H]

Synonym: BRADO1380

Alternate gene names: 146338463

Gene position: 1467668-1468612 (Clockwise)

Preceding gene: 146338462

Following gene: 146338464

Centisome position: 19.68

GC content: 68.36

Gene sequence:

>945_bases
TTGGCCTTCGCGCTGCCGACCGTTGCTGTCGCCGAGGACGCGCCGGTCGAGCAGCAGCTCGTCGACGCGATGAACAAGGT
GTTCGGCGTGCACGCCGGATTCCGCGCCAATCACGCCAAGGGCGTGGTGGTCGAGGGCAAGTTCAAGCCGTCGGCGGAGG
CGGCCGGCTTGAGCAAGGCGGCGCTGTTCAGCGGGGCGGAGATCCCGGTGACGGTGCGGTTCTCCGATTCCACCGGCGTG
CCGAATTTGCCGGACGGCTCGGGCGATGCCAATCCGCACGGCATGGCGGTGAAGTTTCATCTCGCCGACGGCAGCGACGT
CGACCTCGTGATCAACTCGCTGAAGTTCTTCCCCGTCTCGACGGCGGCGGAGCTGCGCGACCTGTTCCTGGCGATCGCCG
ACAGCGGGCCGAACGCGGCCAAGCCGACCAGGCTCGATCAGTTCATCGGCAGCCATCCGTCGGCGCCGGCCGCGCTCGGC
ACCATCGCGACGCCGGACAGCTTTGCCGACGAGGCCTATTTCGGCGTCAACGCCTTCGTGCTCGTGAACAAGGACGGCGC
GAGGCAGGCGGTGCGCTGGCAGATGCTGCCGCAGAAGGTGGTGCATCTCGACAAGGACGACGCCGCCAGGCGCGCGCCGG
ACTTCCTGATGGCCGAGCTGCCGGCGCGGCTGAAGCAGGGGTCCGTGACCTTCCGCTTCATGGCGCAGCTCGCGGCCGCC
GGCGACGATACCAAGGATCCGGCCAAGCCGTGGCCCGACGACCGCAAGCTGGTCGAGCTCGGCGTGCTCACGATCGACAA
GGCGGTCGACGACAGCGACGCCGCGCAGAAGAAGCTCCTGTTCCTGCCGAGCCAGCTCACCGACGGCATCGAGGCCTCCG
ACGATCCGATGATCGACATCCGCAGCGCCGCCTACGCGATCTCGTTCTCGCGGCGCAATCCGTGA

Upstream 100 bases:

>100_bases
GAAAGTCGCTCGCGTGTCAATCGAGGCTGCTATGCTGCATCGCCCCAACAGGAGGATGACGCTGATGAAGACACGCTCGC
TCGTGGCCATGCTGGCCGGA

Downstream 100 bases:

>100_bases
GCGGTTCGCGGCGCGTGAGCGCTGCGACGACGCGCGGGCCGCGAATGCGGATGCATTGCGGCCCCGCTTGCCGGACCCCG
CCGTGGGATCGGTGAGGTCT

Product: catalase

Products: O2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAFALPTVAVAEDAPVEQQLVDAMNKVFGVHAGFRANHAKGVVVEGKFKPSAEAAGLSKAALFSGAEIPVTVRFSDSTGV
PNLPDGSGDANPHGMAVKFHLADGSDVDLVINSLKFFPVSTAAELRDLFLAIADSGPNAAKPTRLDQFIGSHPSAPAALG
TIATPDSFADEAYFGVNAFVLVNKDGARQAVRWQMLPQKVVHLDKDDAARRAPDFLMAELPARLKQGSVTFRFMAQLAAA
GDDTKDPAKPWPDDRKLVELGVLTIDKAVDDSDAAQKKLLFLPSQLTDGIEASDDPMIDIRSAAYAISFSRRNP

Sequences:

>Translated_314_residues
MAFALPTVAVAEDAPVEQQLVDAMNKVFGVHAGFRANHAKGVVVEGKFKPSAEAAGLSKAALFSGAEIPVTVRFSDSTGV
PNLPDGSGDANPHGMAVKFHLADGSDVDLVINSLKFFPVSTAAELRDLFLAIADSGPNAAKPTRLDQFIGSHPSAPAALG
TIATPDSFADEAYFGVNAFVLVNKDGARQAVRWQMLPQKVVHLDKDDAARRAPDFLMAELPARLKQGSVTFRFMAQLAAA
GDDTKDPAKPWPDDRKLVELGVLTIDKAVDDSDAAQKKLLFLPSQLTDGIEASDDPMIDIRSAAYAISFSRRNP
>Mature_313_residues
AFALPTVAVAEDAPVEQQLVDAMNKVFGVHAGFRANHAKGVVVEGKFKPSAEAAGLSKAALFSGAEIPVTVRFSDSTGVP
NLPDGSGDANPHGMAVKFHLADGSDVDLVINSLKFFPVSTAAELRDLFLAIADSGPNAAKPTRLDQFIGSHPSAPAALGT
IATPDSFADEAYFGVNAFVLVNKDGARQAVRWQMLPQKVVHLDKDDAARRAPDFLMAELPARLKQGSVTFRFMAQLAAAG
DDTKDPAKPWPDDRKLVELGVLTIDKAVDDSDAAQKKLLFLPSQLTDGIEASDDPMIDIRSAAYAISFSRRNP

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Escherichia coli, GI48994891, Length=301, Percent_Identity=27.2425249169435, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6

Molecular weight: Translated: 33365; Mature: 33234

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFALPTVAVAEDAPVEQQLVDAMNKVFGVHAGFRANHAKGVVVEGKFKPSAEAAGLSKA
CCEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCCCHH
ALFSGAEIPVTVRFSDSTGVPNLPDGSGDANPHGMAVKFHLADGSDVDLVINSLKFFPVS
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHEECHHEECCC
TAAELRDLFLAIADSGPNAAKPTRLDQFIGSHPSAPAALGTIATPDSFADEAYFGVNAFV
HHHHHHHHHEEEECCCCCCCCCCHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEECCEEEE
LVNKDGARQAVRWQMLPQKVVHLDKDDAARRAPDFLMAELPARLKQGSVTFRFMAQLAAA
EECCCCCHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GDDTKDPAKPWPDDRKLVELGVLTIDKAVDDSDAAQKKLLFLPSQLTDGIEASDDPMIDI
CCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHEEEECCHHHCCCCCCCCCCCEEE
RSAAYAISFSRRNP
CCCEEEEEECCCCC
>Mature Secondary Structure 
AFALPTVAVAEDAPVEQQLVDAMNKVFGVHAGFRANHAKGVVVEGKFKPSAEAAGLSKA
CEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCCCHH
ALFSGAEIPVTVRFSDSTGVPNLPDGSGDANPHGMAVKFHLADGSDVDLVINSLKFFPVS
HHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHEECHHEECCC
TAAELRDLFLAIADSGPNAAKPTRLDQFIGSHPSAPAALGTIATPDSFADEAYFGVNAFV
HHHHHHHHHEEEECCCCCCCCCCHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEECCEEEE
LVNKDGARQAVRWQMLPQKVVHLDKDDAARRAPDFLMAELPARLKQGSVTFRFMAQLAAA
EECCCCCHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHC
GDDTKDPAKPWPDDRKLVELGVLTIDKAVDDSDAAQKKLLFLPSQLTDGIEASDDPMIDI
CCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHEEEECCHHHCCCCCCCCCCCEEE
RSAAYAISFSRRNP
CCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: H2O2

Specific reaction: 2 H2O2 = O2 + 2 H2O

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]