Click here to switch to the map view.

The map label for this gene is pntA2 [H]

Identifier: 146338293

GI number: 146338293

Start: 1273469

End: 1273786

Strand: Direct

Name: pntA2 [H]

Synonym: BRADO1197

Alternate gene names: 146338293

Gene position: 1273469-1273786 (Clockwise)

Preceding gene: 146338292

Following gene: 146338294

Centisome position: 17.08

GC content: 60.69

Gene sequence:

>318_bases
ATGGAACATGTTGTCCAAGCCGTCGATCCCTTCGTTTTCCGGCTGTCGATCTTCGTCCTCGCCGTCTTCGTCGGCTACTT
CGTGGTTTGGTCGGTGACCCCGGCGCTGCACACGCCGCTGATGTCGGTGACCAACGCGATCTCCTCCGTCATCGTTGTCG
GCGCGCTGCTCGCGGTCGGCGTATCCATGGTGTCGAGCGGCAGTGGTCTGGCGCGGGCGTTCGGCTTCATCGCGCTGATC
TTCGCCTGCGTGAACATCTTCGGAGGCTTCCTCGTCACCCAGCGCATGCTGGCGATGTACAAGAAGAAGTCCAAATAA

Upstream 100 bases:

>100_bases
GACGACGAGCTGGTCAAGGCCACGGCTTTGACAAAGGACGGCGCCATCGTCCACCCGAATTTCCAGCCTAAGGCTTAGTT
GAGGATCTAGGAGCAAAGCC

Downstream 100 bases:

>100_bases
CAACGCCGCACAATAACGCCGCGCGACGCGGGATGACAGGCACAACGGGGCATCTGCAATGAACGCCAATCTGTCGGCAC
TCCTTTATCTCGTGGCGGGT

Product: nicotinamide nucleotide transhydrogenase subunit alpha2

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWSVTPALHTPLMSVTNAISSVIVVGALLAVGVSMVSSGSGLARAFGFIALI
FACVNIFGGFLVTQRMLAMYKKKSK

Sequences:

>Translated_105_residues
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWSVTPALHTPLMSVTNAISSVIVVGALLAVGVSMVSSGSGLARAFGFIALI
FACVNIFGGFLVTQRMLAMYKKKSK
>Mature_105_residues
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWSVTPALHTPLMSVTNAISSVIVVGALLAVGVSMVSSGSGLARAFGFIALI
FACVNIFGGFLVTQRMLAMYKKKSK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=95, Percent_Identity=48.4210526315789, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI122939153, Length=95, Percent_Identity=48.4210526315789, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787887, Length=97, Percent_Identity=54.639175257732, Blast_Score=101, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17550456, Length=102, Percent_Identity=47.0588235294118, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 11245; Mature: 11245

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWSVTPALHTPLMSVTNAISSVIVVGALLAVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSMVSSGSGLARAFGFIALIFACVNIFGGFLVTQRMLAMYKKKSK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHVVQAVDPFVFRLSIFVLAVFVGYFVVWSVTPALHTPLMSVTNAISSVIVVGALLAVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSMVSSGSGLARAFGFIALIFACVNIFGGFLVTQRMLAMYKKKSK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]