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The map label for this gene is ruvA [H]

Identifier: 146338241

GI number: 146338241

Start: 1218006

End: 1218623

Strand: Direct

Name: ruvA [H]

Synonym: BRADO1145

Alternate gene names: 146338241

Gene position: 1218006-1218623 (Clockwise)

Preceding gene: 146338240

Following gene: 146338242

Centisome position: 16.33

GC content: 67.64

Gene sequence:

>618_bases
ATGATCGGCAAGCTCAGGGGCCTGATCGATTCCTATGCCGAGGACTTCGTGATCATCGACGTCGGCGGCGTCGGCTATCA
GGTGCACTGCTCGGCGCGCACCCTGCAGGCCTTGCCGTCGCCGGGTGAAGCCGCCACATTGTCGATCGAGACCTATGTGC
GCGAGGACCAGATCAAGCTGTTCGGTTTTCGCTCGGATGTCGAACGGGAATGGTTTCGTCTTTTGCAGACCGTGCAGGGC
GTCGGCGCCAAGGTCGCTCTTGCCGTGCTCGGCACGCTTCCTCCGGCCGATCTCGGCAACGCGATCGCGCTGCGCGACAA
GGCTGCGGTGGCGCGCACGCCGGGCGTGGGGCCCAAGGTGGCCGAGCGCATCGTGACGGAGCTGAAGGACAAGGCGCCGG
CGTTCGCCAATGTCGATCCCGGCGTCGTCAGGCTGTCCGGCGCCATCGAGGAATCCCGCGCGCCGCAGCCGGTCGCGGAT
GCGATCTCCGCGCTCATCAATCTCGGCTACGGCCAGCCGCAGGCCGCCGCCGCCATCGCGGCCGCCTCGCGTGCCGCCGG
CGACAAGGCCGAGACTGCCCAACTCATCCGCCTCGGCCTCAAGGAACTGGCCAAGTAG

Upstream 100 bases:

>100_bases
CTGAGCCGCCCTCGGCCGACGCGGCCGATGCGCTGGCGATCGCGATCACCCACGCCCATCACCGCCAGGGCCAGGCGCTG
CGCATGAAGGTGGCCGGGCT

Downstream 100 bases:

>100_bases
GTTGCAAAGTAGGTCGCCGCGCCGGGCGAGCAGAAGGACAACGATCTTCCCCATGGTGAGCAAGAAGGACAAGGAGCTGA
TCGAGGCGGCCGCGTCGGCG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGKLRGLIDSYAEDFVIIDVGGVGYQVHCSARTLQALPSPGEAATLSIETYVREDQIKLFGFRSDVEREWFRLLQTVQG
VGAKVALAVLGTLPPADLGNAIALRDKAAVARTPGVGPKVAERIVTELKDKAPAFANVDPGVVRLSGAIEESRAPQPVAD
AISALINLGYGQPQAAAAIAAASRAAGDKAETAQLIRLGLKELAK

Sequences:

>Translated_205_residues
MIGKLRGLIDSYAEDFVIIDVGGVGYQVHCSARTLQALPSPGEAATLSIETYVREDQIKLFGFRSDVEREWFRLLQTVQG
VGAKVALAVLGTLPPADLGNAIALRDKAAVARTPGVGPKVAERIVTELKDKAPAFANVDPGVVRLSGAIEESRAPQPVAD
AISALINLGYGQPQAAAAIAAASRAAGDKAETAQLIRLGLKELAK
>Mature_205_residues
MIGKLRGLIDSYAEDFVIIDVGGVGYQVHCSARTLQALPSPGEAATLSIETYVREDQIKLFGFRSDVEREWFRLLQTVQG
VGAKVALAVLGTLPPADLGNAIALRDKAAVARTPGVGPKVAERIVTELKDKAPAFANVDPGVVRLSGAIEESRAPQPVAD
AISALINLGYGQPQAAAAIAAASRAAGDKAETAQLIRLGLKELAK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=206, Percent_Identity=34.9514563106796, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21452; Mature: 21452

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKLRGLIDSYAEDFVIIDVGGVGYQVHCSARTLQALPSPGEAATLSIETYVREDQIKL
CCCHHHHHHHHHCCCEEEEEECCCCEEEEECHHHHHHCCCCCCEEEEEHHHHHCCCCEEE
FGFRSDVEREWFRLLQTVQGVGAKVALAVLGTLPPADLGNAIALRDKAAVARTPGVGPKV
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHCCCCCCHHH
AERIVTELKDKAPAFANVDPGVVRLSGAIEESRAPQPVADAISALINLGYGQPQAAAAIA
HHHHHHHHHHCCCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
AASRAAGDKAETAQLIRLGLKELAK
HHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKLRGLIDSYAEDFVIIDVGGVGYQVHCSARTLQALPSPGEAATLSIETYVREDQIKL
CCCHHHHHHHHHCCCEEEEEECCCCEEEEECHHHHHHCCCCCCEEEEEHHHHHCCCCEEE
FGFRSDVEREWFRLLQTVQGVGAKVALAVLGTLPPADLGNAIALRDKAAVARTPGVGPKV
EECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHCCCCCCHHH
AERIVTELKDKAPAFANVDPGVVRLSGAIEESRAPQPVADAISALINLGYGQPQAAAAIA
HHHHHHHHHHCCCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
AASRAAGDKAETAQLIRLGLKELAK
HHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA