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The map label for this gene is caiD [C]

Identifier: 146338048

GI number: 146338048

Start: 1005606

End: 1006403

Strand: Reverse

Name: caiD [C]

Synonym: BRADO0943

Alternate gene names: 146338048

Gene position: 1006403-1005606 (Counterclockwise)

Preceding gene: 146338049

Following gene: 146338047

Centisome position: 13.5

GC content: 67.54

Gene sequence:

>798_bases
ATGACCGACGGACCGAGCAGCCAAGGTGGCGATGCGCCAAGCACGCCGGTTCTGACGATCGAAGGGCCGCGCGCCACCAT
CCGGCTCAACCGGCCGCGCCATCTCAACCGCCTGCAGCCCGAGGACCTCGGCGCGTTGATGGCGCTGTTCGACCGCGTCG
AAGCCGACGCCGGATTGCGCGTGCTCGTCCTGACCGGGACCGGGCGCGCGTTCAGCGCCGGTTTCGATCTCGGCGCGATC
GGGGGCGGGCCGGAGACCAGCCCGGCAGGTGGCGCGGGCCCATCGTTCGAAGCGGTCGTGGACCGGCTGGAGGACCTGGC
GCTGCCGACGATCTGCCGGCTCAATGGCGGTGTCTATGGCGGGTCGACCGACCTCGCGCTGGCATGCGATTTCCGGATCG
GAGTCGACACCGCAGAAATGTTCATGCCGGCCGCGCGGCTCGGGCTGCACTACTACCCGAACGGCATCAAGCGTTACGTC
TCCCGCCTTGGCGTCGATAATGCCAAGCACCTCTTTCTCACCGCCGAGAAGATCGGCGCCGCCGAAATGCTGCGGATCGG
CTACCTCACCGGCATGGTGGCGGCCGACGCGCTCGATGCCGAGGTCGAACGATTAGCTGCGCTGCTGGCCGGCAACGCGC
CGGCCGCGATGCGCGGCATGAAGCGCGCGATCAACGAGTTTGCCCGCGGCATGCTGGACGATGCGGCGGCTCGCCGCAGA
CATCAGGACAGCCTGAGCGGATCGGAGATCCAGGAGGGCATGAAATCGTTTGCAGAAAAAAGGGCACCGCGGTTTTGA

Upstream 100 bases:

>100_bases
TGCTCGATCTCGTCGATTTTCGCGTGCTGATGGCACGCCACCCCGATCTGGCGCAGAGCATCGATGCCGAGGCCGTGCGC
CGAACCTTGGAGAACAGGAC

Downstream 100 bases:

>100_bases
CGGCAATGCAGCGATCTGTCCGATCAGGATTGCATGCATCCCGCGGTATGCAGCCGGTGTTCCGCCACACGTTCAACGAA
CTATCGACCTAAAGCTCCAA

Product: putative enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTDGPSSQGGDAPSTPVLTIEGPRATIRLNRPRHLNRLQPEDLGALMALFDRVEADAGLRVLVLTGTGRAFSAGFDLGAI
GGGPETSPAGGAGPSFEAVVDRLEDLALPTICRLNGGVYGGSTDLALACDFRIGVDTAEMFMPAARLGLHYYPNGIKRYV
SRLGVDNAKHLFLTAEKIGAAEMLRIGYLTGMVAADALDAEVERLAALLAGNAPAAMRGMKRAINEFARGMLDDAAARRR
HQDSLSGSEIQEGMKSFAEKRAPRF

Sequences:

>Translated_265_residues
MTDGPSSQGGDAPSTPVLTIEGPRATIRLNRPRHLNRLQPEDLGALMALFDRVEADAGLRVLVLTGTGRAFSAGFDLGAI
GGGPETSPAGGAGPSFEAVVDRLEDLALPTICRLNGGVYGGSTDLALACDFRIGVDTAEMFMPAARLGLHYYPNGIKRYV
SRLGVDNAKHLFLTAEKIGAAEMLRIGYLTGMVAADALDAEVERLAALLAGNAPAAMRGMKRAINEFARGMLDDAAARRR
HQDSLSGSEIQEGMKSFAEKRAPRF
>Mature_264_residues
TDGPSSQGGDAPSTPVLTIEGPRATIRLNRPRHLNRLQPEDLGALMALFDRVEADAGLRVLVLTGTGRAFSAGFDLGAIG
GGPETSPAGGAGPSFEAVVDRLEDLALPTICRLNGGVYGGSTDLALACDFRIGVDTAEMFMPAARLGLHYYPNGIKRYVS
RLGVDNAKHLFLTAEKIGAAEMLRIGYLTGMVAADALDAEVERLAALLAGNAPAAMRGMKRAINEFARGMLDDAAARRRH
QDSLSGSEIQEGMKSFAEKRAPRF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=241, Percent_Identity=25.7261410788382, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI221142681, Length=255, Percent_Identity=29.8039215686275, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787659, Length=244, Percent_Identity=27.8688524590164, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787660, Length=252, Percent_Identity=32.1428571428571, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082183, Length=268, Percent_Identity=28.7313432835821, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790281, Length=233, Percent_Identity=28.3261802575107, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=25.6, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=29.6296296296296, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=243, Percent_Identity=27.5720164609054, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17534483, Length=214, Percent_Identity=25.7009345794392, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=203, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129971, Length=241, Percent_Identity=29.4605809128631, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24653477, Length=241, Percent_Identity=29.4605809128631, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=24.8091603053435, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653139, Length=270, Percent_Identity=28.5185185185185, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357171, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24650670, Length=273, Percent_Identity=27.1062271062271, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28026; Mature: 27895

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGPSSQGGDAPSTPVLTIEGPRATIRLNRPRHLNRLQPEDLGALMALFDRVEADAGLR
CCCCCCCCCCCCCCCCEEEEECCCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHCCCCCE
VLVLTGTGRAFSAGFDLGAIGGGPETSPAGGAGPSFEAVVDRLEDLALPTICRLNGGVYG
EEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCEEC
GSTDLALACDFRIGVDTAEMFMPAARLGLHYYPNGIKRYVSRLGVDNAKHLFLTAEKIGA
CCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHHCH
AEMLRIGYLTGMVAADALDAEVERLAALLAGNAPAAMRGMKRAINEFARGMLDDAAARRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HQDSLSGSEIQEGMKSFAEKRAPRF
HHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDGPSSQGGDAPSTPVLTIEGPRATIRLNRPRHLNRLQPEDLGALMALFDRVEADAGLR
CCCCCCCCCCCCCCCEEEEECCCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHCCCCCE
VLVLTGTGRAFSAGFDLGAIGGGPETSPAGGAGPSFEAVVDRLEDLALPTICRLNGGVYG
EEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCEEC
GSTDLALACDFRIGVDTAEMFMPAARLGLHYYPNGIKRYVSRLGVDNAKHLFLTAEKIGA
CCCCEEEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHHCH
AEMLRIGYLTGMVAADALDAEVERLAALLAGNAPAAMRGMKRAINEFARGMLDDAAARRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HQDSLSGSEIQEGMKSFAEKRAPRF
HHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA