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The map label for this gene is murA [H]

Identifier: 146337180

GI number: 146337180

Start: 8037

End: 9332

Strand: Direct

Name: murA [H]

Synonym: BRADO0005

Alternate gene names: 146337180

Gene position: 8037-9332 (Clockwise)

Preceding gene: 146337179

Following gene: 146337181

Centisome position: 0.11

GC content: 69.29

Gene sequence:

>1296_bases
ATGGCGCCCATTCAATACATCGTCGAGGGTGGTCACCGGCTCAAGGGCGCGATCGAGCCCTCCGGCAACAAGAACGCGGC
GCTGCCGATCATCGCCGCGGCGCTGCTGACGGACCATCCCGTGACGCTCGACAACGTGCCGCGCATCCGCGACACCGAGA
CCCTGGTCGAGCTGGTGCGCTCGGTCGGCGCGTCAGCCGAATGGCGCGGGCGGAACCGGCTCGCCATCCACGCCAAGGAG
ATCCGCGCCGCCGATCTCGATCCGGACCTGTGCGCGCGCATCCGCGCCTCGATCCTGCTCGCCGGCCCCCTGCTCGCCCG
CTGCGGCGAAGTGGCGCTGCCGCCGCCGGGCGGCGACGTGATCGGCCGCCGCCGCCTCGACACGCATTTCCTGGCCTTCG
AGCAGCTCGGCGCCACCGTGACGGCGACCGACAAGATCGAGCTGCGCGCCTCCGGCCTGAAGGGCGCCGACGTCTTCCTC
GACGAGCCCAGCGTTACCGCCACCGAGAACGCGCTGGTCGCGGCCGTCGCCGCGCATGGCACGACATACTTGCGCAACGC
CGCGTCCGAGCCGCATGTGCAGGACCTCGCGCATTTCCTGGTGGCGCTCGGGGCCAACATCGAGGGCATCGGCACCAACA
CGATGGTGATCCATGGCGCCAGCACGCTCGGCCAGGCGTCCTATGCGATCCAGCCCGACCACATCGAGGTCGGCTCGCTG
ATCGGCTTGGCCGCGGTGACGCGCTCGCCGTTGCGCATCGTGCGCGCCGGCACCGAGCATCTGCGCTCGATCCGCATGGG
CTTCGAGCGGCTCGGCATCGTCTGCGAGGTCGCCGGCGACGACCTCATCGTGCCCTCTGACCAGACCATGAAGATCAAGG
ACGATTTCGGCGGCCACGTGCCGAAGCTGGAGGACCAGCCCTGGCCGGCGTTCCCCGCCGACGTGATGTCGATCGCGATC
GTCACCGCCACGCAATGCGAGGGCGTGATCCTGATGTTCGAGAAGATGTTCGAGTCGCGGATGTTCTTCGTCGACAAGCT
GATCTCGATGGGCGCCCGCATCGTGCTGTGCGATCCGCACCGCGCCATCGTCGCCGGTCCCAGCCGCCTGCGCGGCGCCC
GCGTCGTCTCCCCCGACATCCGCGCCGGCATGGCCATGCTGCTCGCCGCACTCTGCGCCGAGGGAACGTCTTATATCGAC
AACGCCGACCAGATCGAGCGCGGCTACGAACGCATCGACGAGCGCCTGAACGCACTGGGCGCGAAGATCACCCGCGTGCC
GGAGCGCGGGCGATAA

Upstream 100 bases:

>100_bases
CTGGTTTTCGGATACCCTGGTTCGTATACAGTGTGCCTCGCGCCGTGACGAAGCCGGCGAGTTGCAGCGACCCACGCTTC
GATGCACGGACCCGTCGCGC

Downstream 100 bases:

>100_bases
GCTCGTTCACGCGATATCTTTCCGCGTCATTGCGAGCGCAGCGAAGCAATCCAGAGTCCTTGCTCAGCCCTGCATTGCTT
CGCGCTCGCAATGACGAATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MAPIQYIVEGGHRLKGAIEPSGNKNAALPIIAAALLTDHPVTLDNVPRIRDTETLVELVRSVGASAEWRGRNRLAIHAKE
IRAADLDPDLCARIRASILLAGPLLARCGEVALPPPGGDVIGRRRLDTHFLAFEQLGATVTATDKIELRASGLKGADVFL
DEPSVTATENALVAAVAAHGTTYLRNAASEPHVQDLAHFLVALGANIEGIGTNTMVIHGASTLGQASYAIQPDHIEVGSL
IGLAAVTRSPLRIVRAGTEHLRSIRMGFERLGIVCEVAGDDLIVPSDQTMKIKDDFGGHVPKLEDQPWPAFPADVMSIAI
VTATQCEGVILMFEKMFESRMFFVDKLISMGARIVLCDPHRAIVAGPSRLRGARVVSPDIRAGMAMLLAALCAEGTSYID
NADQIERGYERIDERLNALGAKITRVPERGR

Sequences:

>Translated_431_residues
MAPIQYIVEGGHRLKGAIEPSGNKNAALPIIAAALLTDHPVTLDNVPRIRDTETLVELVRSVGASAEWRGRNRLAIHAKE
IRAADLDPDLCARIRASILLAGPLLARCGEVALPPPGGDVIGRRRLDTHFLAFEQLGATVTATDKIELRASGLKGADVFL
DEPSVTATENALVAAVAAHGTTYLRNAASEPHVQDLAHFLVALGANIEGIGTNTMVIHGASTLGQASYAIQPDHIEVGSL
IGLAAVTRSPLRIVRAGTEHLRSIRMGFERLGIVCEVAGDDLIVPSDQTMKIKDDFGGHVPKLEDQPWPAFPADVMSIAI
VTATQCEGVILMFEKMFESRMFFVDKLISMGARIVLCDPHRAIVAGPSRLRGARVVSPDIRAGMAMLLAALCAEGTSYID
NADQIERGYERIDERLNALGAKITRVPERGR
>Mature_430_residues
APIQYIVEGGHRLKGAIEPSGNKNAALPIIAAALLTDHPVTLDNVPRIRDTETLVELVRSVGASAEWRGRNRLAIHAKEI
RAADLDPDLCARIRASILLAGPLLARCGEVALPPPGGDVIGRRRLDTHFLAFEQLGATVTATDKIELRASGLKGADVFLD
EPSVTATENALVAAVAAHGTTYLRNAASEPHVQDLAHFLVALGANIEGIGTNTMVIHGASTLGQASYAIQPDHIEVGSLI
GLAAVTRSPLRIVRAGTEHLRSIRMGFERLGIVCEVAGDDLIVPSDQTMKIKDDFGGHVPKLEDQPWPAFPADVMSIAIV
TATQCEGVILMFEKMFESRMFFVDKLISMGARIVLCDPHRAIVAGPSRLRGARVVSPDIRAGMAMLLAALCAEGTSYIDN
ADQIERGYERIDERLNALGAKITRVPERGR

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=427, Percent_Identity=38.1733021077283, Blast_Score=254, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46214; Mature: 46083

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPIQYIVEGGHRLKGAIEPSGNKNAALPIIAAALLTDHPVTLDNVPRIRDTETLVELVR
CCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
SVGASAEWRGRNRLAIHAKEIRAADLDPDLCARIRASILLAGPLLARCGEVALPPPGGDV
HHCCCCCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCC
IGRRRLDTHFLAFEQLGATVTATDKIELRASGLKGADVFLDEPSVTATENALVAAVAAHG
CCCHHHHHHHHHHHHHCCEEEECCEEEEEECCCCCCEEEECCCCCCCCCCHHEEHHHHCC
TTYLRNAASEPHVQDLAHFLVALGANIEGIGTNTMVIHGASTLGQASYAIQPDHIEVGSL
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHH
IGLAAVTRSPLRIVRAGTEHLRSIRMGFERLGIVCEVAGDDLIVPSDQTMKIKDDFGGHV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEECCCCCCEEECCCCCCCC
PKLEDQPWPAFPADVMSIAIVTATQCEGVILMFEKMFESRMFFVDKLISMGARIVLCDPH
CCCCCCCCCCCCHHHHHEHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
RAIVAGPSRLRGARVVSPDIRAGMAMLLAALCAEGTSYIDNADQIERGYERIDERLNALG
CEEEECHHHHCCCEEECCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHH
AKITRVPERGR
HHHCCCCCCCC
>Mature Secondary Structure 
APIQYIVEGGHRLKGAIEPSGNKNAALPIIAAALLTDHPVTLDNVPRIRDTETLVELVR
CCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
SVGASAEWRGRNRLAIHAKEIRAADLDPDLCARIRASILLAGPLLARCGEVALPPPGGDV
HHCCCCCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCCCC
IGRRRLDTHFLAFEQLGATVTATDKIELRASGLKGADVFLDEPSVTATENALVAAVAAHG
CCCHHHHHHHHHHHHHCCEEEECCEEEEEECCCCCCEEEECCCCCCCCCCHHEEHHHHCC
TTYLRNAASEPHVQDLAHFLVALGANIEGIGTNTMVIHGASTLGQASYAIQPDHIEVGSL
HHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCHHHH
IGLAAVTRSPLRIVRAGTEHLRSIRMGFERLGIVCEVAGDDLIVPSDQTMKIKDDFGGHV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCEECCCCCCEEECCCCCCCC
PKLEDQPWPAFPADVMSIAIVTATQCEGVILMFEKMFESRMFFVDKLISMGARIVLCDPH
CCCCCCCCCCCCHHHHHEHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
RAIVAGPSRLRGARVVSPDIRAGMAMLLAALCAEGTSYIDNADQIERGYERIDERLNALG
CEEEECHHHHCCCEEECCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHH
AKITRVPERGR
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]