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The map label for this gene is yghZ [H]

Identifier: 146302687

GI number: 146302687

Start: 5995634

End: 5996590

Strand: Reverse

Name: yghZ [H]

Synonym: Fjoh_4960

Alternate gene names: 146302687

Gene position: 5996590-5995634 (Counterclockwise)

Preceding gene: 146302690

Following gene: 146302679

Centisome position: 98.36

GC content: 37.41

Gene sequence:

>957_bases
ATGAAATATAACAGATGCGGGAAAAGTGGATTGCTTCTTCCAGAGATTTCTTTAGGATTGTGGCATAACTTCGGTTCGGT
TGATAATTTTGAAAATGCAGAAAGTATCGCTATTGAAGCTTTTGATAAAGGAATTACTCATTTTGATTTAGCGAATAATT
ACGGGCCGGTTCCAGGATCGGCTGAGGAAAACTTTGGGAAAATCTTGTGGCATAACTTTCAGGGAAATCTGCGCGATGAA
ATCGTGATTTCTACTAAAGCAGGTTACACGATGTGGGACGGTCCTTATGGAGATTGGGGTTCACGAAAATATCTGCTTTC
GAGTTTAGATCAGAGTTTAAAGCGAATGAGTATTGATTATGTTGATATTTTTTACTCACATCGTCCAGATCCAGAAACGC
CGATTGAAGAAACTATGATGGCACTTGATCATGCAGTTAGAAGCGGAAAAGCTTTGTATGTTGGAATTAGTAATTATTCT
GCCGAACAAACGAGAGTTGCCGTTGATGTTTTAAAACAATTAGGAACGCCGTGTTTGATTCATCAGGCGAAATATTCAAT
GCTGGAGCGCTGGGTTGAAAACGGATTATTAGATGTTTTGGAAGAAAAAGGAGTGGGCTGTATTGCGTTTTCGCCTTTGG
CACAAGGACTTTTAACGGATAAATATTTAAACGGAATTCCAGAAAACTCAAGAGCACATAATCCAAACGGACATTTGAAA
GAAGATGAGGTAACACAGGAACGCATTCAGAAATTAATGCAGCTGAATGAAATTGCTCAAAATAGAAACCAGTCTTTGGC
GCAAATGGCTTTGGCTTGGTTGCAAAAAGATAAACGAATTACTTCTGTTTTAATTGGAGCGAGTTCTGTAAAACAATTGT
GCAATAATATTGATTGTCTTCAAAATACTGAATTTTCGCAAGATGAATTAAATGCAATTGAGAAGATATTATCTTAA

Upstream 100 bases:

>100_bases
CAGATTCGGCAGATTTTTTTTATCTCCTAAATTGGCTAAATCTGCGGCAGATTTTTGTATTTTTAAAATCTATTAAAACT
CCAACTTTTAAATTAAAACA

Downstream 100 bases:

>100_bases
TGGTGAATTGTTAATTATAAATTGTTAATTCGTAAAAATACATAATCGTAGATACGCGCCTCTGTGCGTCGACGTCATGT
TTAGATATTATAACCCGACA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKYNRCGKSGLLLPEISLGLWHNFGSVDNFENAESIAIEAFDKGITHFDLANNYGPVPGSAEENFGKILWHNFQGNLRDE
IVISTKAGYTMWDGPYGDWGSRKYLLSSLDQSLKRMSIDYVDIFYSHRPDPETPIEETMMALDHAVRSGKALYVGISNYS
AEQTRVAVDVLKQLGTPCLIHQAKYSMLERWVENGLLDVLEEKGVGCIAFSPLAQGLLTDKYLNGIPENSRAHNPNGHLK
EDEVTQERIQKLMQLNEIAQNRNQSLAQMALAWLQKDKRITSVLIGASSVKQLCNNIDCLQNTEFSQDELNAIEKILS

Sequences:

>Translated_318_residues
MKYNRCGKSGLLLPEISLGLWHNFGSVDNFENAESIAIEAFDKGITHFDLANNYGPVPGSAEENFGKILWHNFQGNLRDE
IVISTKAGYTMWDGPYGDWGSRKYLLSSLDQSLKRMSIDYVDIFYSHRPDPETPIEETMMALDHAVRSGKALYVGISNYS
AEQTRVAVDVLKQLGTPCLIHQAKYSMLERWVENGLLDVLEEKGVGCIAFSPLAQGLLTDKYLNGIPENSRAHNPNGHLK
EDEVTQERIQKLMQLNEIAQNRNQSLAQMALAWLQKDKRITSVLIGASSVKQLCNNIDCLQNTEFSQDELNAIEKILS
>Mature_318_residues
MKYNRCGKSGLLLPEISLGLWHNFGSVDNFENAESIAIEAFDKGITHFDLANNYGPVPGSAEENFGKILWHNFQGNLRDE
IVISTKAGYTMWDGPYGDWGSRKYLLSSLDQSLKRMSIDYVDIFYSHRPDPETPIEETMMALDHAVRSGKALYVGISNYS
AEQTRVAVDVLKQLGTPCLIHQAKYSMLERWVENGLLDVLEEKGVGCIAFSPLAQGLLTDKYLNGIPENSRAHNPNGHLK
EDEVTQERIQKLMQLNEIAQNRNQSLAQMALAWLQKDKRITSVLIGASSVKQLCNNIDCLQNTEFSQDELNAIEKILS

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=326, Percent_Identity=37.4233128834356, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=37.3456790123457, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI27436964, Length=326, Percent_Identity=36.8098159509202, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI27436962, Length=326, Percent_Identity=36.5030674846626, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI27436966, Length=326, Percent_Identity=36.1963190184049, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI27436971, Length=309, Percent_Identity=34.9514563106796, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI41152114, Length=209, Percent_Identity=31.1004784688995, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI223718702, Length=211, Percent_Identity=30.8056872037915, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI41327764, Length=237, Percent_Identity=30.8016877637131, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1789375, Length=319, Percent_Identity=61.7554858934169, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI87081735, Length=302, Percent_Identity=34.7682119205298, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=29.9145299145299, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788070, Length=323, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788081, Length=308, Percent_Identity=25.974025974026, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994888, Length=222, Percent_Identity=27.4774774774775, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=24.4117647058824, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=322, Percent_Identity=25.776397515528, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322615, Length=252, Percent_Identity=25, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319958, Length=254, Percent_Identity=26.3779527559055, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=255, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640980, Length=344, Percent_Identity=28.1976744186047, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI45549126, Length=344, Percent_Identity=28.1976744186047, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646159, Length=319, Percent_Identity=27.5862068965517, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646155, Length=314, Percent_Identity=27.0700636942675, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 35713; Mature: 35713

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNRCGKSGLLLPEISLGLWHNFGSVDNFENAESIAIEAFDKGITHFDLANNYGPVPGS
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCC
AEENFGKILWHNFQGNLRDEIVISTKAGYTMWDGPYGDWGSRKYLLSSLDQSLKRMSIDY
CCCCHHHHEEECCCCCCCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCHH
VDIFYSHRPDPETPIEETMMALDHAVRSGKALYVGISNYSAEQTRVAVDVLKQLGTPCLI
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHH
HQAKYSMLERWVENGLLDVLEEKGVGCIAFSPLAQGLLTDKYLNGIPENSRAHNPNGHLK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
EDEVTQERIQKLMQLNEIAQNRNQSLAQMALAWLQKDKRITSVLIGASSVKQLCNNIDCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHH
QNTEFSQDELNAIEKILS
CCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MKYNRCGKSGLLLPEISLGLWHNFGSVDNFENAESIAIEAFDKGITHFDLANNYGPVPGS
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCC
AEENFGKILWHNFQGNLRDEIVISTKAGYTMWDGPYGDWGSRKYLLSSLDQSLKRMSIDY
CCCCHHHHEEECCCCCCCCEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCHH
VDIFYSHRPDPETPIEETMMALDHAVRSGKALYVGISNYSAEQTRVAVDVLKQLGTPCLI
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHH
HQAKYSMLERWVENGLLDVLEEKGVGCIAFSPLAQGLLTDKYLNGIPENSRAHNPNGHLK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
EDEVTQERIQKLMQLNEIAQNRNQSLAQMALAWLQKDKRITSVLIGASSVKQLCNNIDCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHH
QNTEFSQDELNAIEKILS
CCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]