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The map label for this gene is ureC

Identifier: 146302562

GI number: 146302562

Start: 5852281

End: 5854002

Strand: Reverse

Name: ureC

Synonym: Fjoh_4835

Alternate gene names: 146302562

Gene position: 5854002-5852281 (Counterclockwise)

Preceding gene: 146302563

Following gene: 146302561

Centisome position: 96.02

GC content: 38.97

Gene sequence:

>1722_bases
ATGAGCCTGAAAATAAATAAGCTGAAATATGCCAGCATGTATGGTCCTACAAAAGGAGATAAAATTAGACTGGCCGACAC
AGATATCATTGTTGAGATAGAAAAAGATTTTACCGTTTATGGTGATGAAAATAAATTTGGCGGGGGAAAAACAATCAGAG
ACGGTATGGCTCAGTCTAGTACTGCTACGCGCGATCAGGGAGTTTTAGATCTTGTAATTACCAATGCTACTATTATTGAC
CACTGGGGTATTGTAAAAGCAGATATTGGTATTAAAGATGGTAAAATAGCAGGAATTGGTAAAGCTGGTAATCCAGATAC
AATGGATGGTGTTGAACCTCACATGATTATAGGTGCGAGTACAGAAGCTCACGGTGGTGAAAATTTAATTGTTACTGCTG
GTGGAATTGATACCCATATTCATTTTATCAGCCCTCAGCAAATTGAAACTGCTTTATATAGTGGTGTAACCACAATGATT
GGCGGTGGTACTGGACCTGCTGATGGTACAAATGCTACTACTATTACACCTGGTAAATGGTATATTGAAAAAATGCTGCA
AGCTGCAGAAGCATTCCCTATGAATCTTGGATTTTTTGGAAAAGGAAACTGTTCAACCGAAGCGCCATTGGATGAGCAGA
TTGAGGCTGGTGCTTTAGGTTTAAAAATTCATGAGGATTGGGGTGCTTCGCCTGCAGTAATTGATGCTTCATTAAAAGTT
GCTGATAAATATGATGTTCAGGTGGCAATCCATACTGATACTCTTAACGAAGCAGGTTTCCTTGAAGATACAATGAATGC
AATTAACGGACGTGTGATTCATACTTTTCATACAGAAGGTGCTGGAGGAGGTCACGCTCCGGATATTATTAAAGCTGCAA
TGTATCCTAATGTATTGCCGGCTTCAACAAATCCAACCCGTCCTTATACTGTAAATACAATCGACGAACACTTAGATATG
TTGATGGTATGCCATCACTTAAGCAAAAATATTCCTGAAGACGTTTCATTTGCAGATTCTCGTATTCGTCCGGAAACCAT
TGCAGCAGAAGATATCCTGCATGATATGGGAGTGTTTAGTATCATGAGTTCAGACTCACAAGCTATGGGACGTGTAGGTG
AGGTGGTTACCCGTACTTGGCAGACTGCTGACAAAATGAGAAAACAACGCGGTGACCTTGCAGAAGATAAAGGAAACAAA
AATGACAATTTCCGTGCAAAACGTTACGTGGCTAAATATACAATTAACCCTGCTATTGCACATGGTATTTCACAGTATGT
GGGATCTATTGAGGTAGGAAAAATGGCAGACCTTGTATTATGGAAACCAATGCTGTTTGGTACAAAACCTGAAATTATTA
TTAAAGGAGGGATGATTATTGCAGCTCGTATGGGAGATCCAAATGCTTCTATACCTACGCCGCAGCCAGTTCTTTATCGT
AATATGTTTGGAGCTTTTGGAAAAGCACTGTCTAAAACATGTGCCACTTTTGTTTCTCAGGCTTCTATTAAAAACAATAT
TGCAGAAGAGTATGGATTAGAAAAAATGATTTTACCAGTAACAGGCTGCAGAAACATTTCAAAAAAACATCTGATCCATA
ATGATAAAACTCCTGAAATTACTGTGAATCCAGAAAATTATGAAGTACGTGTTGATGGTGAGAAAATCATCTGCGAACCA
GCAACACATCTTCCAATGGCACAGCGCTATTTCTTATTTTAA

Upstream 100 bases:

>100_bases
TTGGTATCAACAATATCGTGAACGGAGATACTACACTAGAAATAAACAAACAACATAGTTTGGCAAAACTGAAAACTGAA
AACTTTAAAAATAAATAATT

Downstream 100 bases:

>100_bases
TTATTAGAGTTTAAAATAGCGGTTCAGCCTAAAATAGAAAGAAACGCTGCTGGTTAATCCGGCAGCAGTTTCTATCTAAT
TGAACCTTTAGAATGATATG

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MSLKINKLKYASMYGPTKGDKIRLADTDIIVEIEKDFTVYGDENKFGGGKTIRDGMAQSSTATRDQGVLDLVITNATIID
HWGIVKADIGIKDGKIAGIGKAGNPDTMDGVEPHMIIGASTEAHGGENLIVTAGGIDTHIHFISPQQIETALYSGVTTMI
GGGTGPADGTNATTITPGKWYIEKMLQAAEAFPMNLGFFGKGNCSTEAPLDEQIEAGALGLKIHEDWGASPAVIDASLKV
ADKYDVQVAIHTDTLNEAGFLEDTMNAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPYTVNTIDEHLDM
LMVCHHLSKNIPEDVSFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMRKQRGDLAEDKGNK
NDNFRAKRYVAKYTINPAIAHGISQYVGSIEVGKMADLVLWKPMLFGTKPEIIIKGGMIIAARMGDPNASIPTPQPVLYR
NMFGAFGKALSKTCATFVSQASIKNNIAEEYGLEKMILPVTGCRNISKKHLIHNDKTPEITVNPENYEVRVDGEKIICEP
ATHLPMAQRYFLF

Sequences:

>Translated_573_residues
MSLKINKLKYASMYGPTKGDKIRLADTDIIVEIEKDFTVYGDENKFGGGKTIRDGMAQSSTATRDQGVLDLVITNATIID
HWGIVKADIGIKDGKIAGIGKAGNPDTMDGVEPHMIIGASTEAHGGENLIVTAGGIDTHIHFISPQQIETALYSGVTTMI
GGGTGPADGTNATTITPGKWYIEKMLQAAEAFPMNLGFFGKGNCSTEAPLDEQIEAGALGLKIHEDWGASPAVIDASLKV
ADKYDVQVAIHTDTLNEAGFLEDTMNAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPYTVNTIDEHLDM
LMVCHHLSKNIPEDVSFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMRKQRGDLAEDKGNK
NDNFRAKRYVAKYTINPAIAHGISQYVGSIEVGKMADLVLWKPMLFGTKPEIIIKGGMIIAARMGDPNASIPTPQPVLYR
NMFGAFGKALSKTCATFVSQASIKNNIAEEYGLEKMILPVTGCRNISKKHLIHNDKTPEITVNPENYEVRVDGEKIICEP
ATHLPMAQRYFLF
>Mature_572_residues
SLKINKLKYASMYGPTKGDKIRLADTDIIVEIEKDFTVYGDENKFGGGKTIRDGMAQSSTATRDQGVLDLVITNATIIDH
WGIVKADIGIKDGKIAGIGKAGNPDTMDGVEPHMIIGASTEAHGGENLIVTAGGIDTHIHFISPQQIETALYSGVTTMIG
GGTGPADGTNATTITPGKWYIEKMLQAAEAFPMNLGFFGKGNCSTEAPLDEQIEAGALGLKIHEDWGASPAVIDASLKVA
DKYDVQVAIHTDTLNEAGFLEDTMNAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPYTVNTIDEHLDML
MVCHHLSKNIPEDVSFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMRKQRGDLAEDKGNKN
DNFRAKRYVAKYTINPAIAHGISQYVGSIEVGKMADLVLWKPMLFGTKPEIIIKGGMIIAARMGDPNASIPTPQPVLYRN
MFGAFGKALSKTCATFVSQASIKNNIAEEYGLEKMILPVTGCRNISKKHLIHNDKTPEITVNPENYEVRVDGEKIICEPA
THLPMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urease family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_FLAJ1 (A5FAD1)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001197153.1
- ProteinModelPortal:   A5FAD1
- SMR:   A5FAD1
- STRING:   A5FAD1
- GeneID:   5089463
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_4835
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   FJOH376686:FJOH_4835-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 62087; Mature: 61955

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 325-325 BINDING 224-224

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKINKLKYASMYGPTKGDKIRLADTDIIVEIEKDFTVYGDENKFGGGKTIRDGMAQSS
CCEEECEEEEEEECCCCCCCEEEEECCEEEEEEECCEEEECCCCCCCCCCHHHHCCCCCC
TATRDQGVLDLVITNATIIDHWGIVKADIGIKDGKIAGIGKAGNPDTMDGVEPHMIIGAS
CCCCCCCEEEEEEECCEEEECCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEEECC
TEAHGGENLIVTAGGIDTHIHFISPQQIETALYSGVTTMIGGGTGPADGTNATTITPGKW
CCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHCHHHEECCCCCCCCCCCCCEECCHHH
YIEKMLQAAEAFPMNLGFFGKGNCSTEAPLDEQIEAGALGLKIHEDWGASPAVIDASLKV
HHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHCCCEEEEEEECCCCCCCEEEEEEEEE
ADKYDVQVAIHTDTLNEAGFLEDTMNAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLP
ECCEEEEEEEEECCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCC
ASTNPTRPYTVNTIDEHLDMLMVCHHLSKNIPEDVSFADSRIRPETIAAEDILHDMGVFS
CCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
IMSSDSQAMGRVGEVVTRTWQTADKMRKQRGDLAEDKGNKNDNFRAKRYVAKYTINPAIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCHHHH
HGISQYVGSIEVGKMADLVLWKPMLFGTKPEIIIKGGMIIAARMGDPNASIPTPQPVLYR
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCCCCCCHHHHH
NMFGAFGKALSKTCATFVSQASIKNNIAEEYGLEKMILPVTGCRNISKKHLIHNDKTPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCEE
TVNPENYEVRVDGEKIICEPATHLPMAQRYFLF
EECCCCEEEEECCCEEEECCCCCCCCCHHHCCC
>Mature Secondary Structure 
SLKINKLKYASMYGPTKGDKIRLADTDIIVEIEKDFTVYGDENKFGGGKTIRDGMAQSS
CEEECEEEEEEECCCCCCCEEEEECCEEEEEEECCEEEECCCCCCCCCCHHHHCCCCCC
TATRDQGVLDLVITNATIIDHWGIVKADIGIKDGKIAGIGKAGNPDTMDGVEPHMIIGAS
CCCCCCCEEEEEEECCEEEECCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEEECC
TEAHGGENLIVTAGGIDTHIHFISPQQIETALYSGVTTMIGGGTGPADGTNATTITPGKW
CCCCCCCEEEEEECCCEEEEEEECHHHHHHHHHHCHHHEECCCCCCCCCCCCCEECCHHH
YIEKMLQAAEAFPMNLGFFGKGNCSTEAPLDEQIEAGALGLKIHEDWGASPAVIDASLKV
HHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHCCCEEEEEEECCCCCCCEEEEEEEEE
ADKYDVQVAIHTDTLNEAGFLEDTMNAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLP
ECCEEEEEEEEECCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCC
ASTNPTRPYTVNTIDEHLDMLMVCHHLSKNIPEDVSFADSRIRPETIAAEDILHDMGVFS
CCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
IMSSDSQAMGRVGEVVTRTWQTADKMRKQRGDLAEDKGNKNDNFRAKRYVAKYTINPAIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCHHHH
HGISQYVGSIEVGKMADLVLWKPMLFGTKPEIIIKGGMIIAARMGDPNASIPTPQPVLYR
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCCCCCCHHHHH
NMFGAFGKALSKTCATFVSQASIKNNIAEEYGLEKMILPVTGCRNISKKHLIHNDKTPEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCEE
TVNPENYEVRVDGEKIICEPATHLPMAQRYFLF
EECCCCEEEEECCCEEEECCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA