Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 146302442

GI number: 146302442

Start: 5691301

End: 5695353

Strand: Direct

Name: luxQ [H]

Synonym: Fjoh_4715

Alternate gene names: 146302442

Gene position: 5691301-5695353 (Clockwise)

Preceding gene: 146302441

Following gene: 146302443

Centisome position: 93.35

GC content: 31.63

Gene sequence:

>4053_bases
ATGGTAGAAAACTATAGTTTTTTCAATTTCTTGGTTTCAGGTATTGCCGGTTTTGGCAATACCTTAAAATCAATTATGAC
AAACTGGTACGTTTTCCGCTCAGATATTATTTTTTACAACAATCCTAAACTCATCGTTCTGGGTTTCTCATTACTGGGAT
TTTTATCTTTATTAGTTTACCAATTCTTTCGGATAAAGGCAAAAATTGGTAATTTCATTGAGAAAAAGAAAGAAGCCGAA
ACGGTTGCCAGAGAATACCAGCTTTATATTTTATTTTTTGGAATTGCTGTTATTGTAATCGAAATTATAAACGAAATATT
TAAAATCAGGCCAAAGAGTCTGTTAACGATAAATGTTTCAATTGGTATTTCGGTACTTTTATGTTATCTCATAACCGATA
AAATAAAATGGCTCCGCGACAGAATTCAGCGCATTTTTATTATTTGCTTTTTTATTTACATTAGTTATGTAGGCTACAAT
ATTGTTTTTCTCTCCAATGATGTAGTTCCCATAATAGTTTTTTTAATCTCCTTTTTCTTTTCTTATAACATCTTAAAGCC
TATAAAAGTTTATTGGTTTTTCGTAGCACTCGTATTTACATTCCTGATTTTAACGGTAACCTTTCATCTAATTCCAATAA
AATCATCTATCTTATTAATTAATTTCTGCATATTAATTTTCATCATCAACCAAGTTAAATATGCTGTATTATTAAACAAT
AGGGACAATTTTAGATTTGCAAATGAAATTGTACATAAAGGAAATTCATTAACAATTGCCACAGATCAAAAGGGAGAAAT
TTTATTTTGCAGTGAAACCGTAAAGCCAATCCTGGGATATTATCCGGAAGAAGTCATGGGATTAAATTTCTGGAAACTTA
CAAAAGGTGATAAATACAATGCGAATATCCACCCCATTCATCATCATGAAAACAAGATTTATACCCGAAAATTAAAAAGC
AAAAACGGAGAGTATAAATACATTCAATGGAAAGACAAAAAATTTTCTGACGACCTCATTATTAGTATAGGCCAGGATGT
TACAGAACAAATTCTTGTTCAGGACCAATACAAAAACTTAATTCAAACGGCAACAGATATTATTTTTGAAGTCGACGCCG
ATGGACATTTTACCTTTATAAATGAATTTGCTTATTCTGTTTTAGGTTATTCAGAAAATGAAATAGTTGGAAAACATTAC
TCCAATTTTATTCATGAAAATTATTCGATGAGTGCGGTCGATTTTTATGAAAACTTTGAAAACAACGGTTATAAATTTCC
TATTATTGAACTTCCTATTGTAAAGAAGAACGGGCTCGAACTCTGGATTTCGCAAAAAATCATCATCCGCAAAAATGATT
TAGGACAAACAATTGGTTTTGCAGGTATTGCAAGGGATATTACCGAAATAAAAAATGCCGAAAACGAGAAAAAAAGGCGT
CTTGAAAAGATTGAAGCTTATAACAATTCTACCAAAAAATTATCGACCACAGATTTTAGCACTTACGATAATTTAAACAC
CGTTATCGATTATATCATAAAAGAAGCTTCGACAGTAAGTAAATCCAACAGAGTTAGTTTTTGGAAATACAATAAAGATT
TAATCAGCTGTAAAAACTTATACAGCATTGACAACCAAAACGTAACAGATAAAAACATCTTAGACGAAGAATCATATCCT
ATCTATTTTGAAACCTTAAAAAACAAAGCGATAATAAATGCGCCTGATGTTTTTAACAAATTAGAAACTTCTGAATTTCA
AAAGCTTTACTTCACAAAAAATCATATCAAATCGATGCTGGATGTTCCGGTTTTCTTAAGCGGACAATTAGCCGGCGTGG
TTTGTTTCGAAAGCACAGAAGAACAAAGAGATTGGGATAACGAAGATATTAACTATGCCCGAACGATTTCTGATGTGATT
TCACTCGCCATTTCGATGCAGATGCGTTTAGAAACAGAACGACGATTAGAATTTAAAAGTCAGCTCCTCTCCGCACTTTC
TCTTTGTACAGAAAAGTTTTTACTAAGCAAATCGACACAACAGATGTTTCAGGAAACATATGATATAATTGGAAAAGCTT
CAAAAGCAGATCATATGTTTTATTATGAAAGAGATTTTTCTACCAATACCGTAACTCAAAAATACAAATGGTCCAGACAA
GGCATAACGCATCAGATAACGCCTTTGCGCCATATGACCGAAGACAATTTAAAAGAGATCTTTGAAGCGGCAAAAAACAA
ACGAATTGTAAACACTTTTACCCGAAAACTCGAAGATTCGTTTTTTAAACAATTATTAATCAACAATGAGATCAAATCTA
TTTTAATACTTCCGCTTTATATAAACGATATATTTACCGGATTTATTGGTTTTGATGATTGTTCTGAAGAAAGAAAATGG
CTGGAAGAAGAAATTTACATTTTTCAGGTTTTAGCCAATAATATTTCATCTGCATTAGAAAGAAACAGAAACGAATCTAA
AATTATTGAAAGCGAAGAAAAATTCAAGTTAATCGCCAACAATATTCCGGGAACAGTCTATTTGTCAAAATTTGATGCTT
TTTCTACCAAAATCTTTTTAAATGATGAAATCCAAAATCTTACAGGCTATTCTAAAGTTGAATTTATAGAAAATAATCTA
TCATTTTTATCACTCATACATCATGATGACCGCGATGAAGTTATTAATAATCAAATTGATAATCTTCAAAACGGAATGCC
TCTGCATAATATTTACCGAATTAAACGAAAAACCGGTGAATATATCTGGGTTGAAGAATTTGGAGACGTAATTAAAAAAG
GCGACGAAATTGAGTTTGTGGGCGGGATTTATTTTGATATTACCAATAAAAAAGAAACCGAAGATGCTATTAAAGCCAAA
CAATTAGCAGAAGCCGCAAACAAATCTAAATCTGATTTTCTGGCTAATATGTCGCATGAAATTAGAACACCGCTCAATGG
TATTATAGGTTTTACGCATTTATTGATGAAAACTGAACTTGAAGAAATTCAGGAAAAATACATGACAACAATTAATCAAT
CGGCACATTCGCTGCTTGAAATTATCAATGATATTTTGGATTTCTCTAAAATCGAAGCTGGAAAACTGGAGCTTTTTATC
GATTTATATGATATTAAAAAAGTACTCGGTCAGGTATTTGATTTAATTGTTTTTGAATCCAATCAAAAAAGTCTGCAATT
AGAACTCAATGTAGATCATGATGTTCCAAAATACATTTGGACAGATATTGTCAGGATTAAACAAATTTTGATAAACCTGC
TATCAAACGCAGTAAAATTTACCAACGAAGGTTCTATAAAACTGAATGTTTCGGTTTTATCAAAAACAAAAAACAACTTT
TGCACCATCCGTTTTTCTGTAATTGATACCGGAATTGGTATCATGGAAAAAAACCAAAAGAAAATTTTTAAAGCTTTTTC
GCAGGCAGACAGCTCTACAACGAGAAAATTTGGAGGAACCGGTTTAGGTTTAACTATATCCAACCAGCTTTTAGCATTAA
TGGAAAGCCGATTACAGCTGGAAAGTACAATTGGCGAAGGAAGTAACTTTTTCTTCGATTTAAATTTAAAAACCAGCAAT
CAAAGCATTAACGAAAAATACAACAGCGAACTTAAAGGCATCAGCTTAAAATCTGATTTAGATAAAAACGAAGCCAGCAG
TAAAAGCATACGCTTTTTGATTGTCGAAGACAATAAGGTTAATATGCTGCTTTTAAAAACAATTGTAAAAAATCTATATC
AAAATGCTTTTATATTTGAATGTGAAAACGGTTACGAGGCTGTAAAACAATTTGAAAGCATTAATCCAAATCTAGTTTTT
ATGGATATACAAATGCCAATTATGAACGGTTACGAAACCACAAAGGCTATTAGAAATACCATAAGCGGCAAAAATATCCC
CATAATCGCAGTGACAGCAGGTGCCGAAAAAGAAGAACGAAACAAATGCATATCAGCCGGAATGGACGATTATATTTCTA
AACCTATCATGAAAGGTACTGTAGAAGAAACTTTGGAAAAATGGCTGAAATAA

Upstream 100 bases:

>100_bases
AATAAAACCAAAAAATTCTGAAACAAAACAAGAGCTTAACCAACTCTTATTCAGAGTTTTTAAAATATAATTTACTAAAC
CAAAAACATCCCCAAAATCT

Downstream 100 bases:

>100_bases
TTCAAACTAAATTCTCGTTTAATTATAAGTTTTTCCTAAAAATTACATAAATTCGTACAATAAAAAACATAAAAAGCTTA
AAAAGAATATACTATGAAAT

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1350; Mature: 1350

Protein sequence:

>1350_residues
MVENYSFFNFLVSGIAGFGNTLKSIMTNWYVFRSDIIFYNNPKLIVLGFSLLGFLSLLVYQFFRIKAKIGNFIEKKKEAE
TVAREYQLYILFFGIAVIVIEIINEIFKIRPKSLLTINVSIGISVLLCYLITDKIKWLRDRIQRIFIICFFIYISYVGYN
IVFLSNDVVPIIVFLISFFFSYNILKPIKVYWFFVALVFTFLILTVTFHLIPIKSSILLINFCILIFIINQVKYAVLLNN
RDNFRFANEIVHKGNSLTIATDQKGEILFCSETVKPILGYYPEEVMGLNFWKLTKGDKYNANIHPIHHHENKIYTRKLKS
KNGEYKYIQWKDKKFSDDLIISIGQDVTEQILVQDQYKNLIQTATDIIFEVDADGHFTFINEFAYSVLGYSENEIVGKHY
SNFIHENYSMSAVDFYENFENNGYKFPIIELPIVKKNGLELWISQKIIIRKNDLGQTIGFAGIARDITEIKNAENEKKRR
LEKIEAYNNSTKKLSTTDFSTYDNLNTVIDYIIKEASTVSKSNRVSFWKYNKDLISCKNLYSIDNQNVTDKNILDEESYP
IYFETLKNKAIINAPDVFNKLETSEFQKLYFTKNHIKSMLDVPVFLSGQLAGVVCFESTEEQRDWDNEDINYARTISDVI
SLAISMQMRLETERRLEFKSQLLSALSLCTEKFLLSKSTQQMFQETYDIIGKASKADHMFYYERDFSTNTVTQKYKWSRQ
GITHQITPLRHMTEDNLKEIFEAAKNKRIVNTFTRKLEDSFFKQLLINNEIKSILILPLYINDIFTGFIGFDDCSEERKW
LEEEIYIFQVLANNISSALERNRNESKIIESEEKFKLIANNIPGTVYLSKFDAFSTKIFLNDEIQNLTGYSKVEFIENNL
SFLSLIHHDDRDEVINNQIDNLQNGMPLHNIYRIKRKTGEYIWVEEFGDVIKKGDEIEFVGGIYFDITNKKETEDAIKAK
QLAEAANKSKSDFLANMSHEIRTPLNGIIGFTHLLMKTELEEIQEKYMTTINQSAHSLLEIINDILDFSKIEAGKLELFI
DLYDIKKVLGQVFDLIVFESNQKSLQLELNVDHDVPKYIWTDIVRIKQILINLLSNAVKFTNEGSIKLNVSVLSKTKNNF
CTIRFSVIDTGIGIMEKNQKKIFKAFSQADSSTTRKFGGTGLGLTISNQLLALMESRLQLESTIGEGSNFFFDLNLKTSN
QSINEKYNSELKGISLKSDLDKNEASSKSIRFLIVEDNKVNMLLLKTIVKNLYQNAFIFECENGYEAVKQFESINPNLVF
MDIQMPIMNGYETTKAIRNTISGKNIPIIAVTAGAEKEERNKCISAGMDDYISKPIMKGTVEETLEKWLK

Sequences:

>Translated_1350_residues
MVENYSFFNFLVSGIAGFGNTLKSIMTNWYVFRSDIIFYNNPKLIVLGFSLLGFLSLLVYQFFRIKAKIGNFIEKKKEAE
TVAREYQLYILFFGIAVIVIEIINEIFKIRPKSLLTINVSIGISVLLCYLITDKIKWLRDRIQRIFIICFFIYISYVGYN
IVFLSNDVVPIIVFLISFFFSYNILKPIKVYWFFVALVFTFLILTVTFHLIPIKSSILLINFCILIFIINQVKYAVLLNN
RDNFRFANEIVHKGNSLTIATDQKGEILFCSETVKPILGYYPEEVMGLNFWKLTKGDKYNANIHPIHHHENKIYTRKLKS
KNGEYKYIQWKDKKFSDDLIISIGQDVTEQILVQDQYKNLIQTATDIIFEVDADGHFTFINEFAYSVLGYSENEIVGKHY
SNFIHENYSMSAVDFYENFENNGYKFPIIELPIVKKNGLELWISQKIIIRKNDLGQTIGFAGIARDITEIKNAENEKKRR
LEKIEAYNNSTKKLSTTDFSTYDNLNTVIDYIIKEASTVSKSNRVSFWKYNKDLISCKNLYSIDNQNVTDKNILDEESYP
IYFETLKNKAIINAPDVFNKLETSEFQKLYFTKNHIKSMLDVPVFLSGQLAGVVCFESTEEQRDWDNEDINYARTISDVI
SLAISMQMRLETERRLEFKSQLLSALSLCTEKFLLSKSTQQMFQETYDIIGKASKADHMFYYERDFSTNTVTQKYKWSRQ
GITHQITPLRHMTEDNLKEIFEAAKNKRIVNTFTRKLEDSFFKQLLINNEIKSILILPLYINDIFTGFIGFDDCSEERKW
LEEEIYIFQVLANNISSALERNRNESKIIESEEKFKLIANNIPGTVYLSKFDAFSTKIFLNDEIQNLTGYSKVEFIENNL
SFLSLIHHDDRDEVINNQIDNLQNGMPLHNIYRIKRKTGEYIWVEEFGDVIKKGDEIEFVGGIYFDITNKKETEDAIKAK
QLAEAANKSKSDFLANMSHEIRTPLNGIIGFTHLLMKTELEEIQEKYMTTINQSAHSLLEIINDILDFSKIEAGKLELFI
DLYDIKKVLGQVFDLIVFESNQKSLQLELNVDHDVPKYIWTDIVRIKQILINLLSNAVKFTNEGSIKLNVSVLSKTKNNF
CTIRFSVIDTGIGIMEKNQKKIFKAFSQADSSTTRKFGGTGLGLTISNQLLALMESRLQLESTIGEGSNFFFDLNLKTSN
QSINEKYNSELKGISLKSDLDKNEASSKSIRFLIVEDNKVNMLLLKTIVKNLYQNAFIFECENGYEAVKQFESINPNLVF
MDIQMPIMNGYETTKAIRNTISGKNIPIIAVTAGAEKEERNKCISAGMDDYISKPIMKGTVEETLEKWLK
>Mature_1350_residues
MVENYSFFNFLVSGIAGFGNTLKSIMTNWYVFRSDIIFYNNPKLIVLGFSLLGFLSLLVYQFFRIKAKIGNFIEKKKEAE
TVAREYQLYILFFGIAVIVIEIINEIFKIRPKSLLTINVSIGISVLLCYLITDKIKWLRDRIQRIFIICFFIYISYVGYN
IVFLSNDVVPIIVFLISFFFSYNILKPIKVYWFFVALVFTFLILTVTFHLIPIKSSILLINFCILIFIINQVKYAVLLNN
RDNFRFANEIVHKGNSLTIATDQKGEILFCSETVKPILGYYPEEVMGLNFWKLTKGDKYNANIHPIHHHENKIYTRKLKS
KNGEYKYIQWKDKKFSDDLIISIGQDVTEQILVQDQYKNLIQTATDIIFEVDADGHFTFINEFAYSVLGYSENEIVGKHY
SNFIHENYSMSAVDFYENFENNGYKFPIIELPIVKKNGLELWISQKIIIRKNDLGQTIGFAGIARDITEIKNAENEKKRR
LEKIEAYNNSTKKLSTTDFSTYDNLNTVIDYIIKEASTVSKSNRVSFWKYNKDLISCKNLYSIDNQNVTDKNILDEESYP
IYFETLKNKAIINAPDVFNKLETSEFQKLYFTKNHIKSMLDVPVFLSGQLAGVVCFESTEEQRDWDNEDINYARTISDVI
SLAISMQMRLETERRLEFKSQLLSALSLCTEKFLLSKSTQQMFQETYDIIGKASKADHMFYYERDFSTNTVTQKYKWSRQ
GITHQITPLRHMTEDNLKEIFEAAKNKRIVNTFTRKLEDSFFKQLLINNEIKSILILPLYINDIFTGFIGFDDCSEERKW
LEEEIYIFQVLANNISSALERNRNESKIIESEEKFKLIANNIPGTVYLSKFDAFSTKIFLNDEIQNLTGYSKVEFIENNL
SFLSLIHHDDRDEVINNQIDNLQNGMPLHNIYRIKRKTGEYIWVEEFGDVIKKGDEIEFVGGIYFDITNKKETEDAIKAK
QLAEAANKSKSDFLANMSHEIRTPLNGIIGFTHLLMKTELEEIQEKYMTTINQSAHSLLEIINDILDFSKIEAGKLELFI
DLYDIKKVLGQVFDLIVFESNQKSLQLELNVDHDVPKYIWTDIVRIKQILINLLSNAVKFTNEGSIKLNVSVLSKTKNNF
CTIRFSVIDTGIGIMEKNQKKIFKAFSQADSSTTRKFGGTGLGLTISNQLLALMESRLQLESTIGEGSNFFFDLNLKTSN
QSINEKYNSELKGISLKSDLDKNEASSKSIRFLIVEDNKVNMLLLKTIVKNLYQNAFIFECENGYEAVKQFESINPNLVF
MDIQMPIMNGYETTKAIRNTISGKNIPIIAVTAGAEKEERNKCISAGMDDYISKPIMKGTVEETLEKWLK

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=272, Percent_Identity=43.75, Blast_Score=219, Evalue=1e-57,
Organism=Escherichia coli, GI48994928, Length=397, Percent_Identity=31.7380352644836, Blast_Score=206, Evalue=6e-54,
Organism=Escherichia coli, GI1788713, Length=413, Percent_Identity=33.1719128329298, Blast_Score=178, Evalue=2e-45,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=37.8378378378378, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI87081816, Length=396, Percent_Identity=30.050505050505, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=29.3333333333333, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI1788549, Length=271, Percent_Identity=25.4612546125461, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=219, Percent_Identity=27.8538812785388, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=198, Percent_Identity=28.2828282828283, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=30, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=24.0963855421687, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=24.7826086956522, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=23.7209302325581, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=31.9672131147541, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=24.7826086956522, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=141, Percent_Identity=32.6241134751773, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 156226; Mature: 156226

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVENYSFFNFLVSGIAGFGNTLKSIMTNWYVFRSDIIFYNNPKLIVLGFSLLGFLSLLVY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEHHHHHHHHHHHHH
QFFRIKAKIGNFIEKKKEAETVAREYQLYILFFGIAVIVIEIINEIFKIRPKSLLTINVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
IGISVLLCYLITDKIKWLRDRIQRIFIICFFIYISYVGYNIVFLSNDVVPIIVFLISFFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHH
SYNILKPIKVYWFFVALVFTFLILTVTFHLIPIKSSILLINFCILIFIINQVKYAVLLNN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
RDNFRFANEIVHKGNSLTIATDQKGEILFCSETVKPILGYYPEEVMGLNFWKLTKGDKYN
CCCCHHHHHHHHCCCEEEEEECCCCCEEEECHHHHHHHCCCCHHHHCCCEEEECCCCCCC
ANIHPIHHHENKIYTRKLKSKNGEYKYIQWKDKKFSDDLIISIGQDVTEQILVQDQYKNL
CCCCCEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHH
IQTATDIIFEVDADGHFTFINEFAYSVLGYSENEIVGKHYSNFIHENYSMSAVDFYENFE
HHHHHHEEEEECCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHC
NNGYKFPIIELPIVKKNGLELWISQKIIIRKNDLGQTIGFAGIARDITEIKNAENEKKRR
CCCEEEEEEEECEEECCCCEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHH
LEKIEAYNNSTKKLSTTDFSTYDNLNTVIDYIIKEASTVSKSNRVSFWKYNKDLISCKNL
HHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHH
YSIDNQNVTDKNILDEESYPIYFETLKNKAIINAPDVFNKLETSEFQKLYFTKNHIKSML
HCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
DVPVFLSGQLAGVVCFESTEEQRDWDNEDINYARTISDVISLAISMQMRLETERRLEFKS
CCCEEECCCEEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLSALSLCTEKFLLSKSTQQMFQETYDIIGKASKADHMFYYERDFSTNTVTQKYKWSRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHC
GITHQITPLRHMTEDNLKEIFEAAKNKRIVNTFTRKLEDSFFKQLLINNEIKSILILPLY
CCCEECCHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHH
INDIFTGFIGFDDCSEERKWLEEEIYIFQVLANNISSALERNRNESKIIESEEKFKLIAN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCC
NIPGTVYLSKFDAFSTKIFLNDEIQNLTGYSKVEFIENNLSFLSLIHHDDRDEVINNQID
CCCCEEEEEECCCCEEEEEECCHHHHCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
NLQNGMPLHNIYRIKRKTGEYIWVEEFGDVIKKGDEIEFVGGIYFDITNKKETEDAIKAK
HHHCCCCHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHH
QLAEAANKSKSDFLANMSHEIRTPLNGIIGFTHLLMKTELEEIQEKYMTTINQSAHSLLE
HHHHHHCCCHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IINDILDFSKIEAGKLELFIDLYDIKKVLGQVFDLIVFESNQKSLQLELNVDHDVPKYIW
HHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHH
TDIVRIKQILINLLSNAVKFTNEGSIKLNVSVLSKTKNNFCTIRFSVIDTGIGIMEKNQK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCHHCCHHH
KIFKAFSQADSSTTRKFGGTGLGLTISNQLLALMESRLQLESTIGEGSNFFFDLNLKTSN
HHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
QSINEKYNSELKGISLKSDLDKNEASSKSIRFLIVEDNKVNMLLLKTIVKNLYQNAFIFE
CHHHHHHCCHHCCCEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
CENGYEAVKQFESINPNLVFMDIQMPIMNGYETTKAIRNTISGKNIPIIAVTAGAEKEER
ECCCHHHHHHHHCCCCCEEEEEEEEHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHH
NKCISAGMDDYISKPIMKGTVEETLEKWLK
HHHHHCCCHHHHCCCHHCCHHHHHHHHHCC
>Mature Secondary Structure
MVENYSFFNFLVSGIAGFGNTLKSIMTNWYVFRSDIIFYNNPKLIVLGFSLLGFLSLLVY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEHHHHHHHHHHHHH
QFFRIKAKIGNFIEKKKEAETVAREYQLYILFFGIAVIVIEIINEIFKIRPKSLLTINVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEH
IGISVLLCYLITDKIKWLRDRIQRIFIICFFIYISYVGYNIVFLSNDVVPIIVFLISFFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHH
SYNILKPIKVYWFFVALVFTFLILTVTFHLIPIKSSILLINFCILIFIINQVKYAVLLNN
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECC
RDNFRFANEIVHKGNSLTIATDQKGEILFCSETVKPILGYYPEEVMGLNFWKLTKGDKYN
CCCCHHHHHHHHCCCEEEEEECCCCCEEEECHHHHHHHCCCCHHHHCCCEEEECCCCCCC
ANIHPIHHHENKIYTRKLKSKNGEYKYIQWKDKKFSDDLIISIGQDVTEQILVQDQYKNL
CCCCCEECCCCCHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHH
IQTATDIIFEVDADGHFTFINEFAYSVLGYSENEIVGKHYSNFIHENYSMSAVDFYENFE
HHHHHHEEEEECCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHC
NNGYKFPIIELPIVKKNGLELWISQKIIIRKNDLGQTIGFAGIARDITEIKNAENEKKRR
CCCEEEEEEEECEEECCCCEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHH
LEKIEAYNNSTKKLSTTDFSTYDNLNTVIDYIIKEASTVSKSNRVSFWKYNKDLISCKNL
HHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHH
YSIDNQNVTDKNILDEESYPIYFETLKNKAIINAPDVFNKLETSEFQKLYFTKNHIKSML
HCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
DVPVFLSGQLAGVVCFESTEEQRDWDNEDINYARTISDVISLAISMQMRLETERRLEFKS
CCCEEECCCEEEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLLSALSLCTEKFLLSKSTQQMFQETYDIIGKASKADHMFYYERDFSTNTVTQKYKWSRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHC
GITHQITPLRHMTEDNLKEIFEAAKNKRIVNTFTRKLEDSFFKQLLINNEIKSILILPLY
CCCEECCHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHH
INDIFTGFIGFDDCSEERKWLEEEIYIFQVLANNISSALERNRNESKIIESEEKFKLIAN
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCC
NIPGTVYLSKFDAFSTKIFLNDEIQNLTGYSKVEFIENNLSFLSLIHHDDRDEVINNQID
CCCCEEEEEECCCCEEEEEECCHHHHCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHH
NLQNGMPLHNIYRIKRKTGEYIWVEEFGDVIKKGDEIEFVGGIYFDITNKKETEDAIKAK
HHHCCCCHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHH
QLAEAANKSKSDFLANMSHEIRTPLNGIIGFTHLLMKTELEEIQEKYMTTINQSAHSLLE
HHHHHHCCCHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IINDILDFSKIEAGKLELFIDLYDIKKVLGQVFDLIVFESNQKSLQLELNVDHDVPKYIW
HHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCCCHHHHH
TDIVRIKQILINLLSNAVKFTNEGSIKLNVSVLSKTKNNFCTIRFSVIDTGIGIMEKNQK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCHHCCHHH
KIFKAFSQADSSTTRKFGGTGLGLTISNQLLALMESRLQLESTIGEGSNFFFDLNLKTSN
HHHHHHHHCCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCC
QSINEKYNSELKGISLKSDLDKNEASSKSIRFLIVEDNKVNMLLLKTIVKNLYQNAFIFE
CHHHHHHCCHHCCCEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEE
CENGYEAVKQFESINPNLVFMDIQMPIMNGYETTKAIRNTISGKNIPIIAVTAGAEKEER
ECCCHHHHHHHHCCCCCEEEEEEEEHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHHH
NKCISAGMDDYISKPIMKGTVEETLEKWLK
HHHHHCCCHHHHCCCHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]