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The map label for this gene is lytS [H]

Identifier: 146302396

GI number: 146302396

Start: 5646412

End: 5647983

Strand: Direct

Name: lytS [H]

Synonym: Fjoh_4669

Alternate gene names: 146302396

Gene position: 5646412-5647983 (Clockwise)

Preceding gene: 146302395

Following gene: 146302397

Centisome position: 92.61

GC content: 31.49

Gene sequence:

>1572_bases
TTGAAATTTAGATTAAAAAAAATAACATCCCGACGTGCATTTTTAATTTATGTAGCCGTCTCTATTCTTATTACTGTTTC
TTCTGTATATATATTGAGTAATTTGATTACTGATCTTACCGAAAAAGCAAATGAAGAAGCAGCACAGCGTAACTTTATTA
AAAAGCAGGAATTTTTGTCGCAGGAATTCTCAAAATTTCTGGAACAGGAAAACAGAATAAAGCACGTTTTAAAAATAAGT
AAACCAGAAGAACTGGCTTCTAACTTACATGTTTTGTCTTCGGTTCAAAACACCAATTTATTGGTAGCCGATAATTGGTT
TCAAATAAATGATAATAAAATTCAGTTTGGAACTGATTCTATTTCGGGTGACCTAAAAAAAGATGCAGAAGATTTTATCC
AAAAAAATAAAGATCAGGATCACATAAGTGTTATTATTCCGCAGGGAGAAGAATGGGTTTGGAGAATTTATTTTAAACTT
ACTTCAAAAAACACAGTTGTTCGTTATGGCTACGATATCAACTTAAAAAAACTTGTTGATTATTTTTCCAGTATAGATAT
TAAATCGACTAACAATTATGCTTTTATATTTGATAAGTCAGGAAGATGTATTTATCATCCTGAATTGAATTTTATAGGAA
AAAATATTTATGAGGTTTCTTCTACCCGTGCAATTGATACCATATTTCCAAAAAAGCAGGATTATGTAAAAAGAGTTACC
ATGTCTGAATATTTAGGACTGGATGTTATTCGATTTACAAAAAAATTAGACCTTAGAAACACACATTGGTTTATATGTGT
CAATTTTCCAAAAAATGTCAGCGACGAAAATGTAGCGTTGATTAATAAATATTCGACCTGGATATATTCGATTACAACGG
TAATGCTTCTGCTGATTTTCTATTTATTCTCGTATGCCAACAGACGTGCTTACAAAGAGAAAGGAATTGCCATTAAAGAA
AAAAACAGGCTTTTGGTTGAGAATGAAAAAATCATCAAAGAAAAAGCACTTATTCAGCTGCAGCATTTAAAAGAACAGAT
TAATCCGCACTTTTTATTCAATTCGCTCAACTCTCTTTACATGTTAGTTGGAAGCGATGTAAAAACGGCACAAAAATTCA
CACTGAACTTATCCCGTATTTACCGTTATTTAATTGATCCGCCTGAAAAAAATATTGTACCGCTTAAGGATGAATTATTA
TTTATCGAAAAATATATCTTTTTACAGCAGACTCGTTTCAAGGAAGAATTATTCTTTTCTATTAAAATTGAAGATCAGGA
AGCTCTCGAAAAGTTTATTCCGTATCTGGGATTTCAGGTAGTAGTCGAGAATGCTATTAAGCACAATATGGCGACACAGG
AAAATCCGTTAACGACAGAAATTCTAATTCAAAAAGATCAGGTCATAATCACTAATAATCTTCAAAAAAAGACTCACAGC
GAGCCTGGCACAAATTTTGGCTTAAAATACTTGTTAAGTATCTATAACTTCTACTCCAGAACCAATTTAACAACTTCAGA
AAATGACGGCAAATTCGTATGTATTCTGCCATTAATATCCATTCACTCCTAA

Upstream 100 bases:

>100_bases
ACAAGGAACTCATCAGGAATTATTAATGAAAACTGATGGATATTATAAAAACTTATACGATTCTCAATTCTCGGTTGCGA
ATTAAATTACTGGTACTTCT

Downstream 100 bases:

>100_bases
AAAAAAGCCATTCACTCCGTTTTGTTTTTTTTCTGAGCTAAAATCGAATAGTTTCGACGAAAATTAACTTAAACTTAACA
TCAAAATGAAGGAAAAGGCA

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MKFRLKKITSRRAFLIYVAVSILITVSSVYILSNLITDLTEKANEEAAQRNFIKKQEFLSQEFSKFLEQENRIKHVLKIS
KPEELASNLHVLSSVQNTNLLVADNWFQINDNKIQFGTDSISGDLKKDAEDFIQKNKDQDHISVIIPQGEEWVWRIYFKL
TSKNTVVRYGYDINLKKLVDYFSSIDIKSTNNYAFIFDKSGRCIYHPELNFIGKNIYEVSSTRAIDTIFPKKQDYVKRVT
MSEYLGLDVIRFTKKLDLRNTHWFICVNFPKNVSDENVALINKYSTWIYSITTVMLLLIFYLFSYANRRAYKEKGIAIKE
KNRLLVENEKIIKEKALIQLQHLKEQINPHFLFNSLNSLYMLVGSDVKTAQKFTLNLSRIYRYLIDPPEKNIVPLKDELL
FIEKYIFLQQTRFKEELFFSIKIEDQEALEKFIPYLGFQVVVENAIKHNMATQENPLTTEILIQKDQVIITNNLQKKTHS
EPGTNFGLKYLLSIYNFYSRTNLTTSENDGKFVCILPLISIHS

Sequences:

>Translated_523_residues
MKFRLKKITSRRAFLIYVAVSILITVSSVYILSNLITDLTEKANEEAAQRNFIKKQEFLSQEFSKFLEQENRIKHVLKIS
KPEELASNLHVLSSVQNTNLLVADNWFQINDNKIQFGTDSISGDLKKDAEDFIQKNKDQDHISVIIPQGEEWVWRIYFKL
TSKNTVVRYGYDINLKKLVDYFSSIDIKSTNNYAFIFDKSGRCIYHPELNFIGKNIYEVSSTRAIDTIFPKKQDYVKRVT
MSEYLGLDVIRFTKKLDLRNTHWFICVNFPKNVSDENVALINKYSTWIYSITTVMLLLIFYLFSYANRRAYKEKGIAIKE
KNRLLVENEKIIKEKALIQLQHLKEQINPHFLFNSLNSLYMLVGSDVKTAQKFTLNLSRIYRYLIDPPEKNIVPLKDELL
FIEKYIFLQQTRFKEELFFSIKIEDQEALEKFIPYLGFQVVVENAIKHNMATQENPLTTEILIQKDQVIITNNLQKKTHS
EPGTNFGLKYLLSIYNFYSRTNLTTSENDGKFVCILPLISIHS
>Mature_523_residues
MKFRLKKITSRRAFLIYVAVSILITVSSVYILSNLITDLTEKANEEAAQRNFIKKQEFLSQEFSKFLEQENRIKHVLKIS
KPEELASNLHVLSSVQNTNLLVADNWFQINDNKIQFGTDSISGDLKKDAEDFIQKNKDQDHISVIIPQGEEWVWRIYFKL
TSKNTVVRYGYDINLKKLVDYFSSIDIKSTNNYAFIFDKSGRCIYHPELNFIGKNIYEVSSTRAIDTIFPKKQDYVKRVT
MSEYLGLDVIRFTKKLDLRNTHWFICVNFPKNVSDENVALINKYSTWIYSITTVMLLLIFYLFSYANRRAYKEKGIAIKE
KNRLLVENEKIIKEKALIQLQHLKEQINPHFLFNSLNSLYMLVGSDVKTAQKFTLNLSRIYRYLIDPPEKNIVPLKDELL
FIEKYIFLQQTRFKEELFFSIKIEDQEALEKFIPYLGFQVVVENAIKHNMATQENPLTTEILIQKDQVIITNNLQKKTHS
EPGTNFGLKYLLSIYNFYSRTNLTTSENDGKFVCILPLISIHS

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=157, Percent_Identity=32.484076433121, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788446, Length=151, Percent_Identity=33.7748344370861, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61286; Mature: 61286

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRLKKITSRRAFLIYVAVSILITVSSVYILSNLITDLTEKANEEAAQRNFIKKQEFLS
CCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEFSKFLEQENRIKHVLKISKPEELASNLHVLSSVQNTNLLVADNWFQINDNKIQFGTDS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCEEEECCCC
ISGDLKKDAEDFIQKNKDQDHISVIIPQGEEWVWRIYFKLTSKNTVVRYGYDINLKKLVD
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEECCCEEEEEECCCCHHHHHH
YFSSIDIKSTNNYAFIFDKSGRCIYHPELNFIGKNIYEVSSTRAIDTIFPKKQDYVKRVT
HHHCCCEECCCCEEEEEECCCCEEECCCHHHHCCHHHHHCCCCCHHHHCCCHHHHHHHHH
MSEYLGLDVIRFTKKLDLRNTHWFICVNFPKNVSDENVALINKYSTWIYSITTVMLLLIF
HHHHHCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
YLFSYANRRAYKEKGIAIKEKNRLLVENEKIIKEKALIQLQHLKEQINPHFLFNSLNSLY
HHHHHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEE
MLVGSDVKTAQKFTLNLSRIYRYLIDPPEKNIVPLKDELLFIEKYIFLQQTRFKEELFFS
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEE
IKIEDQEALEKFIPYLGFQVVVENAIKHNMATQENPLTTEILIQKDQVIITNNLQKKTHS
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCHHHCCC
EPGTNFGLKYLLSIYNFYSRTNLTTSENDGKFVCILPLISIHS
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MKFRLKKITSRRAFLIYVAVSILITVSSVYILSNLITDLTEKANEEAAQRNFIKKQEFLS
CCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEFSKFLEQENRIKHVLKISKPEELASNLHVLSSVQNTNLLVADNWFQINDNKIQFGTDS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCEEEECCCC
ISGDLKKDAEDFIQKNKDQDHISVIIPQGEEWVWRIYFKLTSKNTVVRYGYDINLKKLVD
CCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEECCCEEEEEECCCCHHHHHH
YFSSIDIKSTNNYAFIFDKSGRCIYHPELNFIGKNIYEVSSTRAIDTIFPKKQDYVKRVT
HHHCCCEECCCCEEEEEECCCCEEECCCHHHHCCHHHHHCCCCCHHHHCCCHHHHHHHHH
MSEYLGLDVIRFTKKLDLRNTHWFICVNFPKNVSDENVALINKYSTWIYSITTVMLLLIF
HHHHHCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
YLFSYANRRAYKEKGIAIKEKNRLLVENEKIIKEKALIQLQHLKEQINPHFLFNSLNSLY
HHHHHHHHHHHHHCCCEEECCCEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEE
MLVGSDVKTAQKFTLNLSRIYRYLIDPPEKNIVPLKDELLFIEKYIFLQQTRFKEELFFS
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEE
IKIEDQEALEKFIPYLGFQVVVENAIKHNMATQENPLTTEILIQKDQVIITNNLQKKTHS
EEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCHHHCCC
EPGTNFGLKYLLSIYNFYSRTNLTTSENDGKFVCILPLISIHS
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]