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The map label for this gene is degS [H]

Identifier: 146302392

GI number: 146302392

Start: 5642138

End: 5643058

Strand: Direct

Name: degS [H]

Synonym: Fjoh_4665

Alternate gene names: 146302392

Gene position: 5642138-5643058 (Clockwise)

Preceding gene: 146302391

Following gene: 146302394

Centisome position: 92.54

GC content: 29.75

Gene sequence:

>921_bases
ATGTCTTTTATTAGAGTTTTCATATTAGTATTTTTCTTTGTTCCAATTGAAAATAAAGCTTTTAGCCAGGATACTATTTC
TTCTGAAAAGTCAAAAACGACAATTTCTGAAAGTTCAAATAAAACCAACGTTTTCAAACAAATCAAACTGGAACAATTAC
GAAATAAAAAAGTCGTAAGCTTATCTATTGTTCTTATTATTATATTGTTTTTTCTTTTCTATTTTGTGTATCAAAACAAC
CGATTAAAACAAAAGATAAAGCGAAAAGACACCAAGCAGAAAATCCTCTTAAATGTAATAAATGCCGGAATTGACAGTCA
GGAAACTGAACAAAAAAAAATTGCTTCTTTTTTACATGATAATATAAATTCGCTTTTATCTTCGGCCGGACTGCATTTAA
ATGTTTTTACAACAAAAACCAATATTCAGTCTGAAGAAATTCAAAAAGCAAAAGCCATTCTGGCACAAGCTCATGATCTT
TTACGAGATATATCACATGACCTTGTTCCTACCCTATTGGTTCGTTTTGGCTTAATTTATGCTTTAGAAGATTTATGCGA
AAGGAATTCTAATTCGAGTATTGAGTTTGCATTTTCAAGCTCAGTTGCGTCAGAAATCAGATATTCTGAAAAATTCGAAA
CGAAGCTTTATTTTATTGTTTCAGAATTGGTGAGTAATATAATTAATCACAGTGAAGCGAAGAAAGCTCAAATTTCACTG
CATGAAAATAAGAATCAGTTAATTATTATTATTCACGACAACGGAAAAGGTTTTGATTCTGAAAAACTCAACGAAATTGA
AGGTTTTGGTTTAAACCGAATCAGGGTTAGAATAAAAAAATTAAAAGGATCATTTTCTATTATATCGCGGGCAAATGAAA
ACACAGGAACTTCTATAAAAATAAAAGTTCCCATTTCGTAA

Upstream 100 bases:

>100_bases
TCAACATAAAAAATACTATCGGACTTGTAAAATATGCTTTAAAAAACAATTTAATTAACGAGTAATTCAATTGAGAAACA
TTCAAAATCAAATAAAATCT

Downstream 100 bases:

>100_bases
TTTTTATTTTTTACCAATTTCTATAATTTCCAGATCTTTTATTTTATCATCGTCTATTACAAAACGAAGCATAGTACGCA
TTTGATGAAATCCGCTTTTT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSFIRVFILVFFFVPIENKAFSQDTISSEKSKTTISESSNKTNVFKQIKLEQLRNKKVVSLSIVLIIILFFLFYFVYQNN
RLKQKIKRKDTKQKILLNVINAGIDSQETEQKKIASFLHDNINSLLSSAGLHLNVFTTKTNIQSEEIQKAKAILAQAHDL
LRDISHDLVPTLLVRFGLIYALEDLCERNSNSSIEFAFSSSVASEIRYSEKFETKLYFIVSELVSNIINHSEAKKAQISL
HENKNQLIIIIHDNGKGFDSEKLNEIEGFGLNRIRVRIKKLKGSFSIISRANENTGTSIKIKVPIS

Sequences:

>Translated_306_residues
MSFIRVFILVFFFVPIENKAFSQDTISSEKSKTTISESSNKTNVFKQIKLEQLRNKKVVSLSIVLIIILFFLFYFVYQNN
RLKQKIKRKDTKQKILLNVINAGIDSQETEQKKIASFLHDNINSLLSSAGLHLNVFTTKTNIQSEEIQKAKAILAQAHDL
LRDISHDLVPTLLVRFGLIYALEDLCERNSNSSIEFAFSSSVASEIRYSEKFETKLYFIVSELVSNIINHSEAKKAQISL
HENKNQLIIIIHDNGKGFDSEKLNEIEGFGLNRIRVRIKKLKGSFSIISRANENTGTSIKIKVPIS
>Mature_305_residues
SFIRVFILVFFFVPIENKAFSQDTISSEKSKTTISESSNKTNVFKQIKLEQLRNKKVVSLSIVLIIILFFLFYFVYQNNR
LKQKIKRKDTKQKILLNVINAGIDSQETEQKKIASFLHDNINSLLSSAGLHLNVFTTKTNIQSEEIQKAKAILAQAHDLL
RDISHDLVPTLLVRFGLIYALEDLCERNSNSSIEFAFSSSVASEIRYSEKFETKLYFIVSELVSNIINHSEAKKAQISLH
ENKNQLIIIIHDNGKGFDSEKLNEIEGFGLNRIRVRIKKLKGSFSIISRANENTGTSIKIKVPIS

Specific function: Member of the two-component regulatory system degS/degU. Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 34888; Mature: 34757

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIRVFILVFFFVPIENKAFSQDTISSEKSKTTISESSNKTNVFKQIKLEQLRNKKVVS
CHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHH
LSIVLIIILFFLFYFVYQNNRLKQKIKRKDTKQKILLNVINAGIDSQETEQKKIASFLHD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NINSLLSSAGLHLNVFTTKTNIQSEEIQKAKAILAQAHDLLRDISHDLVPTLLVRFGLIY
HHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEDLCERNSNSSIEFAFSSSVASEIRYSEKFETKLYFIVSELVSNIINHSEAKKAQISL
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEE
HENKNQLIIIIHDNGKGFDSEKLNEIEGFGLNRIRVRIKKLKGSFSIISRANENTGTSIK
ECCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCEEE
IKVPIS
EEECCC
>Mature Secondary Structure 
SFIRVFILVFFFVPIENKAFSQDTISSEKSKTTISESSNKTNVFKQIKLEQLRNKKVVS
HHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHH
LSIVLIIILFFLFYFVYQNNRLKQKIKRKDTKQKILLNVINAGIDSQETEQKKIASFLHD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NINSLLSSAGLHLNVFTTKTNIQSEEIQKAKAILAQAHDLLRDISHDLVPTLLVRFGLIY
HHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEDLCERNSNSSIEFAFSSSVASEIRYSEKFETKLYFIVSELVSNIINHSEAKKAQISL
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEE
HENKNQLIIIIHDNGKGFDSEKLNEIEGFGLNRIRVRIKKLKGSFSIISRANENTGTSIK
ECCCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCEEE
IKVPIS
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3141378; 3141377; 9384377; 3136143 [H]