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The map label for this gene is ywoG [H]

Identifier: 146302337

GI number: 146302337

Start: 5573533

End: 5574720

Strand: Reverse

Name: ywoG [H]

Synonym: Fjoh_4610

Alternate gene names: 146302337

Gene position: 5574720-5573533 (Counterclockwise)

Preceding gene: 146302338

Following gene: 146302334

Centisome position: 91.44

GC content: 36.62

Gene sequence:

>1188_bases
ATGCATCCTAAAAATAAATCAATTTATACTCTTCAATTCATTTTGCTTTGCATGAGTTCTCTTTTGTTCTCGTCGAGTTT
TAATATGATTATTCCGGAGCTTCCGAGTTATTTAAGCAGTTTGGGCGGGGCAGAATATAAAGGATTTATTATTTCGCTTT
TTACACTAACAGCTGCTATATCAAGACCTTTTAGCGGTAAGCTTACAGATAAATGGGGGCGTGTTCCTGTAATGGCTGTT
GGATCTGTTGTATGTTTGATTTGTGGTTTTTTGTATCCAATACTAAGTTCAGTTTCGGGATTTTTGTTTTTGCGTTTGGT
TCATGGTTTTTCAACTGGATTTAAACCAACAGCAACTTCTGCTTATGTTGCAGATATTATTCCGCAGGAACGCTGGGGCG
AAGCTTTAGGAATGCATGGTTTGTGTTTTAGTATTGGCGGAGCTTTAGGGCCTGCGCTGGGCGGAATGGTTGTAAATGCG
TATGGAATTGATGTAATGTTTTACAGTTCTTCGTTTCTTGCTTTTTTGTCTATCGTTATTGTAATGAATATGAAAGAAAC
TTTAGCCGCAAAAGAAAAACTTCATAAATCGATGTTTTATATTGGAAGAAAAGATATTATTGATATTGGAGCGCTTCCTG
CCGGAGTTATTACTTTTTTTTCTTATACGGCTTATGGTCTAATACTTACTTTAATTCCGGATTGGAGCGAACATCTGGGG
GCAGAAAATAAAGGAGTATTTTTTACGGCGTTTACGATTGCTTCTGTTTTAGTACGATTTGGTGCTGGAAAAGTTTCTGA
CAGACACGGACGTACAAATGTTATACTCGCAGGATTAATTGTTACTTCTATTGCATTATTTGTAATTAGTACCGGAAATA
GTATTACAGTACTTTTAACAGGAGCCGCTATTTACGGAATGGGTACAGGTATATTATCACCGGCAATTAATGCATGGACT
ATCGATTTGAGTAATCCGCAGCACCGTGGAAAAGCCATAGCCACAATGTATATTTCTATGGAGTTAGGAATTGGTTTGGG
TGCTTTACTTGGAGGAAGTTACTATAGCGATCAAATATCCCGTATTCCTCAAATAATGAAAGTAGATATTCTGGTCTTGT
TTATGGGAGTTCTGTATCTTTTATACTGGAAAAGAAAATCTGCCAATAAAAAGATACAGAACAATTAA

Upstream 100 bases:

>100_bases
GCAGTAATAGATAAATTTTGCAGAAGTTTTATCTAAATAGAAGTCTATATTTGCAGACTTAAATTTTTCTCTTTGTAGAT
ACTACTTTAATAATTTGATA

Downstream 100 bases:

>100_bases
AAACAGGATTTTCTGTTATTTTGCTAATTCTAAATGCAGAATAGGGTAAGGTTTTCCGCAGCCGTCAACATCAGAAGTAG
ATTTTAATTCGAAACCGAAA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MHPKNKSIYTLQFILLCMSSLLFSSSFNMIIPELPSYLSSLGGAEYKGFIISLFTLTAAISRPFSGKLTDKWGRVPVMAV
GSVVCLICGFLYPILSSVSGFLFLRLVHGFSTGFKPTATSAYVADIIPQERWGEALGMHGLCFSIGGALGPALGGMVVNA
YGIDVMFYSSSFLAFLSIVIVMNMKETLAAKEKLHKSMFYIGRKDIIDIGALPAGVITFFSYTAYGLILTLIPDWSEHLG
AENKGVFFTAFTIASVLVRFGAGKVSDRHGRTNVILAGLIVTSIALFVISTGNSITVLLTGAAIYGMGTGILSPAINAWT
IDLSNPQHRGKAIATMYISMELGIGLGALLGGSYYSDQISRIPQIMKVDILVLFMGVLYLLYWKRKSANKKIQNN

Sequences:

>Translated_395_residues
MHPKNKSIYTLQFILLCMSSLLFSSSFNMIIPELPSYLSSLGGAEYKGFIISLFTLTAAISRPFSGKLTDKWGRVPVMAV
GSVVCLICGFLYPILSSVSGFLFLRLVHGFSTGFKPTATSAYVADIIPQERWGEALGMHGLCFSIGGALGPALGGMVVNA
YGIDVMFYSSSFLAFLSIVIVMNMKETLAAKEKLHKSMFYIGRKDIIDIGALPAGVITFFSYTAYGLILTLIPDWSEHLG
AENKGVFFTAFTIASVLVRFGAGKVSDRHGRTNVILAGLIVTSIALFVISTGNSITVLLTGAAIYGMGTGILSPAINAWT
IDLSNPQHRGKAIATMYISMELGIGLGALLGGSYYSDQISRIPQIMKVDILVLFMGVLYLLYWKRKSANKKIQNN
>Mature_395_residues
MHPKNKSIYTLQFILLCMSSLLFSSSFNMIIPELPSYLSSLGGAEYKGFIISLFTLTAAISRPFSGKLTDKWGRVPVMAV
GSVVCLICGFLYPILSSVSGFLFLRLVHGFSTGFKPTATSAYVADIIPQERWGEALGMHGLCFSIGGALGPALGGMVVNA
YGIDVMFYSSSFLAFLSIVIVMNMKETLAAKEKLHKSMFYIGRKDIIDIGALPAGVITFFSYTAYGLILTLIPDWSEHLG
AENKGVFFTAFTIASVLVRFGAGKVSDRHGRTNVILAGLIVTSIALFVISTGNSITVLLTGAAIYGMGTGILSPAINAWT
IDLSNPQHRGKAIATMYISMELGIGLGALLGGSYYSDQISRIPQIMKVDILVLFMGVLYLLYWKRKSANKKIQNN

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=370, Percent_Identity=25.4054054054054, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42695; Mature: 42695

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPKNKSIYTLQFILLCMSSLLFSSSFNMIIPELPSYLSSLGGAEYKGFIISLFTLTAAI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SRPFSGKLTDKWGRVPVMAVGSVVCLICGFLYPILSSVSGFLFLRLVHGFSTGFKPTATS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AYVADIIPQERWGEALGMHGLCFSIGGALGPALGGMVVNAYGIDVMFYSSSFLAFLSIVI
HHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECEEEEEECHHHHHHHHHHH
VMNMKETLAAKEKLHKSMFYIGRKDIIDIGALPAGVITFFSYTAYGLILTLIPDWSEHLG
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCC
AENKGVFFTAFTIASVLVRFGAGKVSDRHGRTNVILAGLIVTSIALFVISTGNSITVLLT
CCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCEEEEEEE
GAAIYGMGTGILSPAINAWTIDLSNPQHRGKAIATMYISMELGIGLGALLGGSYYSDQIS
CHHHHHCCCHHHCCCCCEEEEECCCCHHHCCEEEEEEEEEECCCCHHHHHCCCHHHHHHH
RIPQIMKVDILVLFMGVLYLLYWKRKSANKKIQNN
HCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHPKNKSIYTLQFILLCMSSLLFSSSFNMIIPELPSYLSSLGGAEYKGFIISLFTLTAAI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
SRPFSGKLTDKWGRVPVMAVGSVVCLICGFLYPILSSVSGFLFLRLVHGFSTGFKPTATS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
AYVADIIPQERWGEALGMHGLCFSIGGALGPALGGMVVNAYGIDVMFYSSSFLAFLSIVI
HHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEECEEEEEECHHHHHHHHHHH
VMNMKETLAAKEKLHKSMFYIGRKDIIDIGALPAGVITFFSYTAYGLILTLIPDWSEHLG
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCC
AENKGVFFTAFTIASVLVRFGAGKVSDRHGRTNVILAGLIVTSIALFVISTGNSITVLLT
CCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCEEEEEEE
GAAIYGMGTGILSPAINAWTIDLSNPQHRGKAIATMYISMELGIGLGALLGGSYYSDQIS
CHHHHHCCCHHHCCCCCEEEEECCCCHHHCCEEEEEEEEEECCCCHHHHHCCCHHHHHHH
RIPQIMKVDILVLFMGVLYLLYWKRKSANKKIQNN
HCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]