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The map label for this gene is gcp [H]

Identifier: 146302320

GI number: 146302320

Start: 5556875

End: 5557897

Strand: Direct

Name: gcp [H]

Synonym: Fjoh_4593

Alternate gene names: 146302320

Gene position: 5556875-5557897 (Clockwise)

Preceding gene: 146302314

Following gene: 146302321

Centisome position: 91.14

GC content: 36.36

Gene sequence:

>1023_bases
ATGCAAAATTCAGAGGTTTTTATTCTTGCCATCGAAAGTTCATGCGACGATACTGCTGCCGCGGTTTTACATAACGACAA
AGTACTCTCAAATGTTGTAGCCAATCAGTTAATTCACAATCAATACGGCGGTGTAGTTCCTGAATTAGCTTCGAGAGCAC
ACCAGCAAAACATAGTTCCTGTAATCGATGCTGCACTTCGCAAAGCAAATGTACAAAAAGAACAGCTATCTGCCATTGCC
TTTACACAAGGTCCCGGCCTAATGGGATCACTTTTGGTAGGAAGTTCTTTTGGTAAATCGTTATCATTGGCTTTAAATAT
TCCGTTAATCGCTGTAAATCACATGCATGCCCATATTTTAGCGCATTTTATTGACGAAGAAGGATACGATAAACCAGAAT
TTCCTTTTTTAGCTTTAACAATTAGTGGCGGACATACGCAGATTGTAAAAGTGAACAGTTTTTTTGACATGGAAATTATT
GGAGAAACTACAGATGACGCGGTTGGAGAAGCTTTTGATAAAAGTGCAAAAATATTAGGACTTCCTTATCCGGGCGGGCC
TTTAATTGATAAATATGCCAAAGAAGGAAACCCAAAAGCTTTTACTTTTACGAAACCAAAAGTTCCGGGATTGGATTTTA
GTTTTTCCGGACTAAAAACAGCTATTTTATATTTCATTCAAAAAAACAAACAGGAAAATCCAAATTTCATCGAAGAAAAC
CTAAACGATATCTGTGCTTCAATTCAGCATACGATTATCGAAATTTTGATGGATAAATTAAAACTGGCTGTAAAAGAAAC
CGGAATTAAACAAATCGCTATTGGCGGCGGGGTTTCTGCAAATTCAGGAATCAGGACTACTTTAAAAGAAAGTGAAGCCA
AATACGGCTGGAAAACTTTTATTCCAAAATTTGAATACACTACAGATAATGCCGCAATGATAGGAATTGTAGGCTACCAA
AAATATTTATCAAAACGTTTTGAAGATTCTTCAGTAGTTTCTAAAGCACGAATTCAGTTTTAA

Upstream 100 bases:

>100_bases
CGGCTGTTTTGATAAAAATTCTTTAATTTTGGCATCTGCTTCAATCAAAGAAATTTCAAAATTTGATTTGTCAAATATAA
TCCAAAATTCGTGCCTTTAT

Downstream 100 bases:

>100_bases
TTATGCAGTTATTTTACAATCCGGATATAGACGAAACAACCGAAAGTTTTTCTTTTGATAAAGAAGAAAGCAAACACATT
ATAAAAGTTTTACGCAAGAA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQNSEVFILAIESSCDDTAAAVLHNDKVLSNVVANQLIHNQYGGVVPELASRAHQQNIVPVIDAALRKANVQKEQLSAIA
FTQGPGLMGSLLVGSSFGKSLSLALNIPLIAVNHMHAHILAHFIDEEGYDKPEFPFLALTISGGHTQIVKVNSFFDMEII
GETTDDAVGEAFDKSAKILGLPYPGGPLIDKYAKEGNPKAFTFTKPKVPGLDFSFSGLKTAILYFIQKNKQENPNFIEEN
LNDICASIQHTIIEILMDKLKLAVKETGIKQIAIGGGVSANSGIRTTLKESEAKYGWKTFIPKFEYTTDNAAMIGIVGYQ
KYLSKRFEDSSVVSKARIQF

Sequences:

>Translated_340_residues
MQNSEVFILAIESSCDDTAAAVLHNDKVLSNVVANQLIHNQYGGVVPELASRAHQQNIVPVIDAALRKANVQKEQLSAIA
FTQGPGLMGSLLVGSSFGKSLSLALNIPLIAVNHMHAHILAHFIDEEGYDKPEFPFLALTISGGHTQIVKVNSFFDMEII
GETTDDAVGEAFDKSAKILGLPYPGGPLIDKYAKEGNPKAFTFTKPKVPGLDFSFSGLKTAILYFIQKNKQENPNFIEEN
LNDICASIQHTIIEILMDKLKLAVKETGIKQIAIGGGVSANSGIRTTLKESEAKYGWKTFIPKFEYTTDNAAMIGIVGYQ
KYLSKRFEDSSVVSKARIQF
>Mature_340_residues
MQNSEVFILAIESSCDDTAAAVLHNDKVLSNVVANQLIHNQYGGVVPELASRAHQQNIVPVIDAALRKANVQKEQLSAIA
FTQGPGLMGSLLVGSSFGKSLSLALNIPLIAVNHMHAHILAHFIDEEGYDKPEFPFLALTISGGHTQIVKVNSFFDMEII
GETTDDAVGEAFDKSAKILGLPYPGGPLIDKYAKEGNPKAFTFTKPKVPGLDFSFSGLKTAILYFIQKNKQENPNFIEEN
LNDICASIQHTIIEILMDKLKLAVKETGIKQIAIGGGVSANSGIRTTLKESEAKYGWKTFIPKFEYTTDNAAMIGIVGYQ
KYLSKRFEDSSVVSKARIQF

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=337, Percent_Identity=34.7181008902077, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI8923380, Length=337, Percent_Identity=28.486646884273, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI1789445, Length=337, Percent_Identity=43.026706231454, Blast_Score=283, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17557464, Length=333, Percent_Identity=29.7297297297297, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71995670, Length=322, Percent_Identity=32.9192546583851, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320099, Length=350, Percent_Identity=32.8571428571429, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322891, Length=316, Percent_Identity=26.8987341772152, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20129063, Length=359, Percent_Identity=32.033426183844, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI21357207, Length=348, Percent_Identity=31.8965517241379, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37077; Mature: 37077

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNSEVFILAIESSCDDTAAAVLHNDKVLSNVVANQLIHNQYGGVVPELASRAHQQNIVP
CCCCCEEEEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHH
VIDAALRKANVQKEQLSAIAFTQGPGLMGSLLVGSSFGKSLSLALNIPLIAVNHMHAHIL
HHHHHHHHCCCCHHHHHEEEEECCCCCHHHHHHCCCCCCCEEEEEECCEEEECHHHHHHH
AHFIDEEGYDKPEFPFLALTISGGHTQIVKVNSFFDMEIIGETTDDAVGEAFDKSAKILG
HHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCEEEEEEECCCCCHHHHHHHCCCCCEEE
LPYPGGPLIDKYAKEGNPKAFTFTKPKVPGLDFSFSGLKTAILYFIQKNKQENPNFIEEN
CCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
LNDICASIQHTIIEILMDKLKLAVKETGIKQIAIGGGVSANSGIRTTLKESEAKYGWKTF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHC
IPKFEYTTDNAAMIGIVGYQKYLSKRFEDSSVVSKARIQF
CCCEEECCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MQNSEVFILAIESSCDDTAAAVLHNDKVLSNVVANQLIHNQYGGVVPELASRAHQQNIVP
CCCCCEEEEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHH
VIDAALRKANVQKEQLSAIAFTQGPGLMGSLLVGSSFGKSLSLALNIPLIAVNHMHAHIL
HHHHHHHHCCCCHHHHHEEEEECCCCCHHHHHHCCCCCCCEEEEEECCEEEECHHHHHHH
AHFIDEEGYDKPEFPFLALTISGGHTQIVKVNSFFDMEIIGETTDDAVGEAFDKSAKILG
HHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCEEEEEEECCCCCHHHHHHHCCCCCEEE
LPYPGGPLIDKYAKEGNPKAFTFTKPKVPGLDFSFSGLKTAILYFIQKNKQENPNFIEEN
CCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
LNDICASIQHTIIEILMDKLKLAVKETGIKQIAIGGGVSANSGIRTTLKESEAKYGWKTF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHC
IPKFEYTTDNAAMIGIVGYQKYLSKRFEDSSVVSKARIQF
CCCEEECCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA