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The map label for this gene is ybbF [C]

Identifier: 146302304

GI number: 146302304

Start: 5536806

End: 5537630

Strand: Direct

Name: ybbF [C]

Synonym: Fjoh_4577

Alternate gene names: 146302304

Gene position: 5536806-5537630 (Clockwise)

Preceding gene: 146302300

Following gene: 146302305

Centisome position: 90.81

GC content: 32.73

Gene sequence:

>825_bases
TTGAAAAAACGAAATGTCGAATTGGTCATTATTTCTGATGTCCATTTAGGAACTTACGGAAGTCACGCCAAAGAGCTAAA
CAACTACTTATCAAGCATTAAACCCAAAACCTTAGTCCTAAACGGAGATATTATTGATGCCTGGCAGTTTAGAAAATCTT
ATTTCCCAAAAGCCCATTTAAGAGTTATTCAACGCATTATAGGGATGGCTTCAAAAGGTACAAAAGTGTATTATATTACC
GGAAATCACGATGAGATTCTTCGTAAATTCAGTGATATGAACATGGGTAATTTTTCTTTGGTCGATAAATTAGTTTTAGA
ATTAGACGACAAAAAGGCGTGGATTTTTCATGGAGATGTTTTTGATGCTTCTGTACAACATTCTAAATGGATCGCAAAAC
TGGGAGGTTTAGGTTATGACTACTTAATCCTTATGAACCGATTTGCAAACTGGTGTCTTGCAAAATTAGGACGCGAGCCT
TATTCATTTTCTAAAAAAATAAAAGCCAGTGTAAAAAAAGCAGTTAAATTTATCTCAGATTTTGAAACTACTGCAACTGA
TTTGGCTATCGAAAAAAATTACGATTATGTTATCTGTGGTCATATACACGAACCAAAAATACTTACCAAAGAAAACAAAC
ACGGTTCTACTTTATATTTGAATTCTGGTGACTGGGTCGAAAATTTAACAGCTCTCGAATACCACAAAAAGCGCTGGAAA
TTATATTCGTACACACACAGTAATTTTACTGAAGAAGAAAATCTTTTTGAAATGGAAGATATTTTAACATCGCAGTTAAT
TTCAAATATTATTCTTAAAAAATAA

Upstream 100 bases:

>100_bases
AAATCACAATTTATTAAAATTGACCTCAAATTAGTAACCTTTTCATAAAATAAATCCAGCAAGATTTTCTTTCATTTGTG
GAACTTCAAATTAAGAAAAA

Downstream 100 bases:

>100_bases
TGCCAACCTGCATTATAAAGCACTGTAGACGTTGTTTTTAACTTTTCGGCCTATCGAAAATTCTAAAAAATGTGAATTAT
ATAACAATTTCTAAAAATAT

Product: metallophosphoesterase

Products: 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1; UMP [C]

Alternate protein names: Ser/Thr Protein Phosphatase Family Protein; Calcineurin-Like Phosphoesterase; UDP-2 3-Diacylglucosamine Hydrolase; Metallo-Phosphoesterase; Metallo-Phosphoesterase Protein; Phosphoesterase; Calcineurin Phosphohydrolase Superfamily Protein; Calcineurin-Like Phosphoesterase Family; Metallo-Dependent Phosphoesterase; Metallophosphoesterase Protein

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKKRNVELVIISDVHLGTYGSHAKELNNYLSSIKPKTLVLNGDIIDAWQFRKSYFPKAHLRVIQRIIGMASKGTKVYYIT
GNHDEILRKFSDMNMGNFSLVDKLVLELDDKKAWIFHGDVFDASVQHSKWIAKLGGLGYDYLILMNRFANWCLAKLGREP
YSFSKKIKASVKKAVKFISDFETTATDLAIEKNYDYVICGHIHEPKILTKENKHGSTLYLNSGDWVENLTALEYHKKRWK
LYSYTHSNFTEEENLFEMEDILTSQLISNIILKK

Sequences:

>Translated_274_residues
MKKRNVELVIISDVHLGTYGSHAKELNNYLSSIKPKTLVLNGDIIDAWQFRKSYFPKAHLRVIQRIIGMASKGTKVYYIT
GNHDEILRKFSDMNMGNFSLVDKLVLELDDKKAWIFHGDVFDASVQHSKWIAKLGGLGYDYLILMNRFANWCLAKLGREP
YSFSKKIKASVKKAVKFISDFETTATDLAIEKNYDYVICGHIHEPKILTKENKHGSTLYLNSGDWVENLTALEYHKKRWK
LYSYTHSNFTEEENLFEMEDILTSQLISNIILKK
>Mature_274_residues
MKKRNVELVIISDVHLGTYGSHAKELNNYLSSIKPKTLVLNGDIIDAWQFRKSYFPKAHLRVIQRIIGMASKGTKVYYIT
GNHDEILRKFSDMNMGNFSLVDKLVLELDDKKAWIFHGDVFDASVQHSKWIAKLGGLGYDYLILMNRFANWCLAKLGREP
YSFSKKIKASVKKAVKFISDFETTATDLAIEKNYDYVICGHIHEPKILTKENKHGSTLYLNSGDWVENLTALEYHKKRWK
LYSYTHSNFTEEENLFEMEDILTSQLISNIILKK

Specific function: Lipid A biosynthesis [C]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31724; Mature: 31724

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRNVELVIISDVHLGTYGSHAKELNNYLSSIKPKTLVLNGDIIDAWQFRKSYFPKAHL
CCCCCEEEEEEECEECCCCCHHHHHHHHHHHHCCCCEEEEECCEEHHHHHHHHHCCHHHH
RVIQRIIGMASKGTKVYYITGNHDEILRKFSDMNMGNFSLVDKLVLELDDKKAWIFHGDV
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCC
FDASVQHSKWIAKLGGLGYDYLILMNRFANWCLAKLGREPYSFSKKIKASVKKAVKFISD
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FETTATDLAIEKNYDYVICGHIHEPKILTKENKHGSTLYLNSGDWVENLTALEYHKKRWK
HCCHHHHEEEECCCCEEEECCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHE
LYSYTHSNFTEEENLFEMEDILTSQLISNIILKK
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKRNVELVIISDVHLGTYGSHAKELNNYLSSIKPKTLVLNGDIIDAWQFRKSYFPKAHL
CCCCCEEEEEEECEECCCCCHHHHHHHHHHHHCCCCEEEEECCEEHHHHHHHHHCCHHHH
RVIQRIIGMASKGTKVYYITGNHDEILRKFSDMNMGNFSLVDKLVLELDDKKAWIFHGDV
HHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCC
FDASVQHSKWIAKLGGLGYDYLILMNRFANWCLAKLGREPYSFSKKIKASVKKAVKFISD
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FETTATDLAIEKNYDYVICGHIHEPKILTKENKHGSTLYLNSGDWVENLTALEYHKKRWK
HCCHHHHEEEECCCCEEEECCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHE
LYSYTHSNFTEEENLFEMEDILTSQLISNIILKK
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; UDP-2,3-bis(3-hydroxymyristoyl)glucosamine [C]

Specific reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1 + UMP [C]

General reaction: Lipid A biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA