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The map label for this gene is aroC

Identifier: 146302303

GI number: 146302303

Start: 5535559

End: 5536617

Strand: Reverse

Name: aroC

Synonym: Fjoh_4576

Alternate gene names: 146302303

Gene position: 5536617-5535559 (Counterclockwise)

Preceding gene: 146302306

Following gene: 146302302

Centisome position: 90.81

GC content: 38.9

Gene sequence:

>1059_bases
ATGGCAGGAAACAGCTACGGCACCCTATATAAAGTTACTACATTTGGAGAATCTCATGGTGAAGCTCTAGGCGGTATTAT
AGACGGATGTCCATCAGGAATAGAACTTGATTTCGAAGCGATAGAAGTTGAAATGTCCCGTAGAAAACCAGGACAATCGG
CTATCGTAACACAAAGAAAAGAACCAGACGCGGTTCAGTTTCTATCAGGAATATTTGAAGGAAAAACTACAGGAACCCCA
ATTGGTTTTATTATTCCGAATACCAATCAAAAATCAGATGATTACTCTCATATAAAAGATAATTACAGACCAAGTCATGC
TGATTATGTATATGACCAAAAATACGGTTTTCGTGATTATCGCGGAGGCGGAAGAAGTTCTGCACGTGAAACAGCCAGCA
GAGTAGTAGCAGGAGCTATTGCAAAACAAATGCTTCCAGAAATTAAAATTAATGCTTATGTTTCTTCTGTAGGTCCTATT
CATTTAGATACACCTTATCAGGATTTAGATTTTTCTAAAATCGAAAGCAATCCGGTTCGCTGCCCTGATGAAAAATCAGC
AGCTATTATGGAAGAATATATTCGTGATATCCGCAAACAAGGAGATACTGTAGGAGGAGTTGTTTCGTGTGTAATTCAAA
ATGTACCCGTTGGTTTAGGCGAGCCTGTTTTTGATAAATTACATGCTGAATTAGGAAAAGCAATGCTTTCTATCAATGCC
GTAAAAGGTTTTGAATACGGAAGCGGTTTCTCTGGTTCTGAAATGAAAGGAAGCGAACACAACGATTTATACAATCCGGA
CGGAACGACAAAAACAAATCTTTCAGGAGGAATCCAGGGCGGAATAAGCAACGGAATGGATATTTATTTCAGAGTTGCTT
TTAAACCTGTTGCGACTATTATGCAGACTCAGGATTCTTTAGATAATAAAGGTAATATTACACCAATGACCGGAAAAGGA
CGTCATGATCCGTGCGTGGTGCCTCGTGCAGTACCAATCGTTGAGGCGATGGCTGCGATTGTTTTGGCAGATTTTTATTT
AATCAACAAAACATATTAA

Upstream 100 bases:

>100_bases
AAATTGTGATTTTTAAACTGTTTAATCTTTAATTAATATTACCAATTTTTAATTTTTTAATTTAATTCATAAAACTTACA
TTTGCTCAAAACAATTTACA

Downstream 100 bases:

>100_bases
TAAAAGTAAGGCAGTGAGGGTCTTATATTTTAATAATTAAAAAACAAATTAATGCAAGTAACAGAAACTAAGAAAAAATC
ATTTTTAACAGGACTTACAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAGNSYGTLYKVTTFGESHGEALGGIIDGCPSGIELDFEAIEVEMSRRKPGQSAIVTQRKEPDAVQFLSGIFEGKTTGTP
IGFIIPNTNQKSDDYSHIKDNYRPSHADYVYDQKYGFRDYRGGGRSSARETASRVVAGAIAKQMLPEIKINAYVSSVGPI
HLDTPYQDLDFSKIESNPVRCPDEKSAAIMEEYIRDIRKQGDTVGGVVSCVIQNVPVGLGEPVFDKLHAELGKAMLSINA
VKGFEYGSGFSGSEMKGSEHNDLYNPDGTTKTNLSGGIQGGISNGMDIYFRVAFKPVATIMQTQDSLDNKGNITPMTGKG
RHDPCVVPRAVPIVEAMAAIVLADFYLINKTY

Sequences:

>Translated_352_residues
MAGNSYGTLYKVTTFGESHGEALGGIIDGCPSGIELDFEAIEVEMSRRKPGQSAIVTQRKEPDAVQFLSGIFEGKTTGTP
IGFIIPNTNQKSDDYSHIKDNYRPSHADYVYDQKYGFRDYRGGGRSSARETASRVVAGAIAKQMLPEIKINAYVSSVGPI
HLDTPYQDLDFSKIESNPVRCPDEKSAAIMEEYIRDIRKQGDTVGGVVSCVIQNVPVGLGEPVFDKLHAELGKAMLSINA
VKGFEYGSGFSGSEMKGSEHNDLYNPDGTTKTNLSGGIQGGISNGMDIYFRVAFKPVATIMQTQDSLDNKGNITPMTGKG
RHDPCVVPRAVPIVEAMAAIVLADFYLINKTY
>Mature_351_residues
AGNSYGTLYKVTTFGESHGEALGGIIDGCPSGIELDFEAIEVEMSRRKPGQSAIVTQRKEPDAVQFLSGIFEGKTTGTPI
GFIIPNTNQKSDDYSHIKDNYRPSHADYVYDQKYGFRDYRGGGRSSARETASRVVAGAIAKQMLPEIKINAYVSSVGPIH
LDTPYQDLDFSKIESNPVRCPDEKSAAIMEEYIRDIRKQGDTVGGVVSCVIQNVPVGLGEPVFDKLHAELGKAMLSINAV
KGFEYGSGFSGSEMKGSEHNDLYNPDGTTKTNLSGGIQGGISNGMDIYFRVAFKPVATIMQTQDSLDNKGNITPMTGKGR
HDPCVVPRAVPIVEAMAAIVLADFYLINKTY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=350, Percent_Identity=52.8571428571429, Blast_Score=340, Evalue=7e-95,
Organism=Saccharomyces cerevisiae, GI6321290, Length=365, Percent_Identity=49.3150684931507, Blast_Score=336, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_FLAJ1 (A5FB38)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001196894.1
- ProteinModelPortal:   A5FB38
- SMR:   A5FB38
- STRING:   A5FB38
- GeneID:   5092887
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_4576
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   TATIGKE
- ProtClustDB:   PRK05382
- BioCyc:   FJOH376686:FJOH_4576-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38158; Mature: 38027

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSYGTLYKVTTFGESHGEALGGIIDGCPSGIELDFEAIEVEMSRRKPGQSAIVTQRK
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEHHHEEEEHHHCCCCCCCEEECCC
EPDAVQFLSGIFEGKTTGTPIGFIIPNTNQKSDDYSHIKDNYRPSHADYVYDQKYGFRDY
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCC
RGGGRSSARETASRVVAGAIAKQMLPEIKINAYVSSVGPIHLDTPYQDLDFSKIESNPVR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCHHHHCCCCCC
CPDEKSAAIMEEYIRDIRKQGDTVGGVVSCVIQNVPVGLGEPVFDKLHAELGKAMLSINA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VKGFEYGSGFSGSEMKGSEHNDLYNPDGTTKTNLSGGIQGGISNGMDIYFRVAFKPVATI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHH
MQTQDSLDNKGNITPMTGKGRHDPCVVPRAVPIVEAMAAIVLADFYLINKTY
HHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGNSYGTLYKVTTFGESHGEALGGIIDGCPSGIELDFEAIEVEMSRRKPGQSAIVTQRK
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEHHHEEEEHHHCCCCCCCEEECCC
EPDAVQFLSGIFEGKTTGTPIGFIIPNTNQKSDDYSHIKDNYRPSHADYVYDQKYGFRDY
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCC
RGGGRSSARETASRVVAGAIAKQMLPEIKINAYVSSVGPIHLDTPYQDLDFSKIESNPVR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCHHHHCCCCCC
CPDEKSAAIMEEYIRDIRKQGDTVGGVVSCVIQNVPVGLGEPVFDKLHAELGKAMLSINA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VKGFEYGSGFSGSEMKGSEHNDLYNPDGTTKTNLSGGIQGGISNGMDIYFRVAFKPVATI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHH
MQTQDSLDNKGNITPMTGKGRHDPCVVPRAVPIVEAMAAIVLADFYLINKTY
HHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA