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The map label for this gene is luxQ [H]

Identifier: 146302301

GI number: 146302301

Start: 5531924

End: 5534113

Strand: Reverse

Name: luxQ [H]

Synonym: Fjoh_4574

Alternate gene names: 146302301

Gene position: 5534113-5531924 (Counterclockwise)

Preceding gene: 146302302

Following gene: 146302298

Centisome position: 90.77

GC content: 31.1

Gene sequence:

>2190_bases
ATGCCCCACATACGGATTTTTTTATTTACACTGCTATTTCTGAATTGTTTCAGCAATTTTGCCGTAGCACAATCTGAACC
GGTTTCAGAAGCCCGGATAAACAGATTAATTAAGGAGGCCTGGGATGATTTTAAAGACTCCAATTTCGAAAGATCTCTCA
TTACTTCACGTGTAGCATTAAATTATGCCACAGCAGCAAAAAATGATAATTTAATTGCAAAGGCATACAAAGTTATTGCC
GGAAATTATAACGAATTATCAGAAATTGATAAAGCTCTTTTCTTTTACAATAAAGGTTTATACTACGCAAATAAAACAGA
CAACGATTCGTTAAAGTACAGTCTTCACAACAATATAGGAAACATTTATTGTTTCGAAAAAAAGCAGTTTGATAAAGGGA
TAGATTATTACCAAAAATCAATTGCTTACAGTTTAAAAACAAACAACAGCGATCAGATTTATTTTACCAATGTCAATATT
GCCTGGGCTTATTTTGATATTGGAAGATTTGATGCAGGATATCCGTACTTAAAATTTGTTGGCGATCATGTTGAAAAATA
CGGAGATGCTTCCACAGAAATTATTGTGTATATGCTGAATGGAATGTATTCTAGTTACAAAAACGAAAATACAGCCGCTA
ATTCTTATTTTTTAAAAGCAATTGCCGCCGGAGAAAACAGCGATGAAAAATCGGATTTGTCTTATACACATTTAGAATAT
TCAAAATTCTTAACCAAAATAAAGAATTATAAAGAGGCTTATAAGCATCTTGTAAAGTTTAATGAAATTACAGAGGAACT
TTATAATCAGGAAAAATTAAAAAAAGCATCAATTGCCGGATTCAATTTAGAGCTGGATGAATATAAAAGACAGATTGACA
AAATTGAAAATGAAAAAACATCACAGTCTCAAAGTCTTAAAAAATCAAGAATTATCGTAATCCTGTTTATACTCACATCT
CTAATCTTACTTTTTTTAATTGTAACGCTGATTAAGAATATAGGATTTAAGAAAAAACACAATTTAGAGCTCTTAGAGGC
AAAAGAAATTGCAGAAGAAGCCTCATTACTCAAAACCCAATTTATTTCGACTATAAGCCACGAATTGCGTACACCACTGT
ATGGTGTGGTAGGAATAACAAATATGCTTCTTGAAGAACACAAAGAATTATCGCAGAGCCAGCATTTAAGTGCTTTAAAA
TTTTCGGCACGATATTTACTTTCCTTAGTTAACGATATTCTTCAAATTAATAAAATTGAAGAAAACAAAGTAGTTTTAGA
AAGCTTGACATTTAATATTTCGGATGAAATAACAATGATCAAAAATTCACTTTCTTTTCTATCCCAAAAAAATAATAACA
AAATTAATGTTGAAATAGACGATTATATTCCGGAGTATTTAATTGGTGATAAACTTCGACTGGGTCAGATTTTAATGAAT
TTAGTGAGCAATGCGCTAAAGTTTACAAAAAACGGGGAAGTTGATATTATCGTTAAACTACATAAGATAGAAGGGAAATT
ATACTATCTGGATTTTTTGATAAGAGATAACGGAGTTGGAATTGCGGCTGTAGATCAAAATAAAATATTCGAAAAATTCG
TTCAGGTAGGACGAAAAGATGAAGATTATCAGGGAACGGGATTAGGTTTAAGTATAGTAAAACGATTATTGGGGCTTTTT
GGAAGTACAATTACGCTGGAAAGTGATTTAGGTGCAGGAACTGCATTTTCATTTGTAATTCCGTTTGAACATGATCCTCA
AAAAACAAAAAAAATAATTGAAGATATAGAGGTGGATTTAACATCAAGCGAAATTTATAAAATTCTTATTGTAGAAGATA
ATCTAATTAACCAGCTGGTTACTAAAAAGATTATCGAAAAAAATAATTTTGTCTGCAAAGTCGTTGATGACGGTTTTGGA
GCGCTTACAATATTAGAGAAAGAAAGATTTGATCTTATTTTAATGGATATTAATATGCCGTTAATGAATGGTTTTGAAGC
TACAAAACGCATTCGGCTGTTAGGGGTAAAAACGCCTATAGTGGCGTTGACTGCTTTTGATAAAGACGAAATTACAGATG
AGGCACTTTCATCAGGAATGAATGATATTATTGTAAAGCCTTTTGAGCCTGTAAAATTGTTTAAGATTATAAATTACTTA
ATAATAGAAGCGAAAAACGCTGGTTTTTAA

Upstream 100 bases:

>100_bases
AGAAAACAATACAAGATAACCGAAAAGAAAAGCTGTATTTTTATAGGAAATACGGCTTTTTTTTATTTTTAAGTGTATAT
TTGATAAAATTAGCCGATTG

Downstream 100 bases:

>100_bases
TACCAGCGTTTTTTATTTTGTTTTGAAGCACTTGATTTTCTCGATTTGTGAGCACCGCCGCTTCTGTTTGAATTTTTAGG
TTTTTCTCCTGCTTCAGGAC

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MPHIRIFLFTLLFLNCFSNFAVAQSEPVSEARINRLIKEAWDDFKDSNFERSLITSRVALNYATAAKNDNLIAKAYKVIA
GNYNELSEIDKALFFYNKGLYYANKTDNDSLKYSLHNNIGNIYCFEKKQFDKGIDYYQKSIAYSLKTNNSDQIYFTNVNI
AWAYFDIGRFDAGYPYLKFVGDHVEKYGDASTEIIVYMLNGMYSSYKNENTAANSYFLKAIAAGENSDEKSDLSYTHLEY
SKFLTKIKNYKEAYKHLVKFNEITEELYNQEKLKKASIAGFNLELDEYKRQIDKIENEKTSQSQSLKKSRIIVILFILTS
LILLFLIVTLIKNIGFKKKHNLELLEAKEIAEEASLLKTQFISTISHELRTPLYGVVGITNMLLEEHKELSQSQHLSALK
FSARYLLSLVNDILQINKIEENKVVLESLTFNISDEITMIKNSLSFLSQKNNNKINVEIDDYIPEYLIGDKLRLGQILMN
LVSNALKFTKNGEVDIIVKLHKIEGKLYYLDFLIRDNGVGIAAVDQNKIFEKFVQVGRKDEDYQGTGLGLSIVKRLLGLF
GSTITLESDLGAGTAFSFVIPFEHDPQKTKKIIEDIEVDLTSSEIYKILIVEDNLINQLVTKKIIEKNNFVCKVVDDGFG
ALTILEKERFDLILMDINMPLMNGFEATKRIRLLGVKTPIVALTAFDKDEITDEALSSGMNDIIVKPFEPVKLFKIINYL
IIEAKNAGF

Sequences:

>Translated_729_residues
MPHIRIFLFTLLFLNCFSNFAVAQSEPVSEARINRLIKEAWDDFKDSNFERSLITSRVALNYATAAKNDNLIAKAYKVIA
GNYNELSEIDKALFFYNKGLYYANKTDNDSLKYSLHNNIGNIYCFEKKQFDKGIDYYQKSIAYSLKTNNSDQIYFTNVNI
AWAYFDIGRFDAGYPYLKFVGDHVEKYGDASTEIIVYMLNGMYSSYKNENTAANSYFLKAIAAGENSDEKSDLSYTHLEY
SKFLTKIKNYKEAYKHLVKFNEITEELYNQEKLKKASIAGFNLELDEYKRQIDKIENEKTSQSQSLKKSRIIVILFILTS
LILLFLIVTLIKNIGFKKKHNLELLEAKEIAEEASLLKTQFISTISHELRTPLYGVVGITNMLLEEHKELSQSQHLSALK
FSARYLLSLVNDILQINKIEENKVVLESLTFNISDEITMIKNSLSFLSQKNNNKINVEIDDYIPEYLIGDKLRLGQILMN
LVSNALKFTKNGEVDIIVKLHKIEGKLYYLDFLIRDNGVGIAAVDQNKIFEKFVQVGRKDEDYQGTGLGLSIVKRLLGLF
GSTITLESDLGAGTAFSFVIPFEHDPQKTKKIIEDIEVDLTSSEIYKILIVEDNLINQLVTKKIIEKNNFVCKVVDDGFG
ALTILEKERFDLILMDINMPLMNGFEATKRIRLLGVKTPIVALTAFDKDEITDEALSSGMNDIIVKPFEPVKLFKIINYL
IIEAKNAGF
>Mature_728_residues
PHIRIFLFTLLFLNCFSNFAVAQSEPVSEARINRLIKEAWDDFKDSNFERSLITSRVALNYATAAKNDNLIAKAYKVIAG
NYNELSEIDKALFFYNKGLYYANKTDNDSLKYSLHNNIGNIYCFEKKQFDKGIDYYQKSIAYSLKTNNSDQIYFTNVNIA
WAYFDIGRFDAGYPYLKFVGDHVEKYGDASTEIIVYMLNGMYSSYKNENTAANSYFLKAIAAGENSDEKSDLSYTHLEYS
KFLTKIKNYKEAYKHLVKFNEITEELYNQEKLKKASIAGFNLELDEYKRQIDKIENEKTSQSQSLKKSRIIVILFILTSL
ILLFLIVTLIKNIGFKKKHNLELLEAKEIAEEASLLKTQFISTISHELRTPLYGVVGITNMLLEEHKELSQSQHLSALKF
SARYLLSLVNDILQINKIEENKVVLESLTFNISDEITMIKNSLSFLSQKNNNKINVEIDDYIPEYLIGDKLRLGQILMNL
VSNALKFTKNGEVDIIVKLHKIEGKLYYLDFLIRDNGVGIAAVDQNKIFEKFVQVGRKDEDYQGTGLGLSIVKRLLGLFG
STITLESDLGAGTAFSFVIPFEHDPQKTKKIIEDIEVDLTSSEIYKILIVEDNLINQLVTKKIIEKNNFVCKVVDDGFGA
LTILEKERFDLILMDINMPLMNGFEATKRIRLLGVKTPIVALTAFDKDEITDEALSSGMNDIIVKPFEPVKLFKIINYLI
IEAKNAGF

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=373, Percent_Identity=35.1206434316354, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1788713, Length=369, Percent_Identity=32.7913279132791, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI1789149, Length=393, Percent_Identity=30.7888040712468, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=34.0659340659341, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081816, Length=398, Percent_Identity=28.643216080402, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=29.6747967479675, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=26.7241379310345, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=27.4809160305344, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=294, Percent_Identity=24.4897959183673, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=24.6861924686192, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=35.7798165137615, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87082012, Length=102, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=118, Percent_Identity=41.5254237288136, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322044, Length=122, Percent_Identity=40.9836065573771, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83311; Mature: 83180

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHIRIFLFTLLFLNCFSNFAVAQSEPVSEARINRLIKEAWDDFKDSNFERSLITSRVAL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NYATAAKNDNLIAKAYKVIAGNYNELSEIDKALFFYNKGLYYANKTDNDSLKYSLHNNIG
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCC
NIYCFEKKQFDKGIDYYQKSIAYSLKTNNSDQIYFTNVNIAWAYFDIGRFDAGYPYLKFV
CEEEEEHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCHHHHHH
GDHVEKYGDASTEIIVYMLNGMYSSYKNENTAANSYFLKAIAAGENSDEKSDLSYTHLEY
HHHHHHHCCCCHHEEEEEHHHHHHHHCCCCCCHHHHHHHHEECCCCCCCCCCCCHHHHHH
SKFLTKIKNYKEAYKHLVKFNEITEELYNQEKLKKASIAGFNLELDEYKRQIDKIENEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
SQSQSLKKSRIIVILFILTSLILLFLIVTLIKNIGFKKKHNLELLEAKEIAEEASLLKTQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FISTISHELRTPLYGVVGITNMLLEEHKELSQSQHLSALKFSARYLLSLVNDILQINKIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENKVVLESLTFNISDEITMIKNSLSFLSQKNNNKINVEIDDYIPEYLIGDKLRLGQILMN
CCCEEEEHEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHCCCHHHHHHHHH
LVSNALKFTKNGEVDIIVKLHKIEGKLYYLDFLIRDNGVGIAAVDQNKIFEKFVQVGRKD
HHHHHHHHCCCCCEEEEEEEEEECCEEEEEEEEEECCCCEEEEECHHHHHHHHHHHCCCC
EDYQGTGLGLSIVKRLLGLFGSTITLESDLGAGTAFSFVIPFEHDPQKTKKIIEDIEVDL
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCE
TSSEIYKILIVEDNLINQLVTKKIIEKNNFVCKVVDDGFGALTILEKERFDLILMDINMP
ECCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEEECCCH
LMNGFEATKRIRLLGVKTPIVALTAFDKDEITDEALSSGMNDIIVKPFEPVKLFKIINYL
HHCCHHHHHEEEEEEECCCEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
IIEAKNAGF
EEEECCCCC
>Mature Secondary Structure 
PHIRIFLFTLLFLNCFSNFAVAQSEPVSEARINRLIKEAWDDFKDSNFERSLITSRVAL
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NYATAAKNDNLIAKAYKVIAGNYNELSEIDKALFFYNKGLYYANKTDNDSLKYSLHNNIG
HHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECCCC
NIYCFEKKQFDKGIDYYQKSIAYSLKTNNSDQIYFTNVNIAWAYFDIGRFDAGYPYLKFV
CEEEEEHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCHHHHHH
GDHVEKYGDASTEIIVYMLNGMYSSYKNENTAANSYFLKAIAAGENSDEKSDLSYTHLEY
HHHHHHHCCCCHHEEEEEHHHHHHHHCCCCCCHHHHHHHHEECCCCCCCCCCCCHHHHHH
SKFLTKIKNYKEAYKHLVKFNEITEELYNQEKLKKASIAGFNLELDEYKRQIDKIENEKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
SQSQSLKKSRIIVILFILTSLILLFLIVTLIKNIGFKKKHNLELLEAKEIAEEASLLKTQ
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
FISTISHELRTPLYGVVGITNMLLEEHKELSQSQHLSALKFSARYLLSLVNDILQINKIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENKVVLESLTFNISDEITMIKNSLSFLSQKNNNKINVEIDDYIPEYLIGDKLRLGQILMN
CCCEEEEHEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHCCCHHHHHHHHH
LVSNALKFTKNGEVDIIVKLHKIEGKLYYLDFLIRDNGVGIAAVDQNKIFEKFVQVGRKD
HHHHHHHHCCCCCEEEEEEEEEECCEEEEEEEEEECCCCEEEEECHHHHHHHHHHHCCCC
EDYQGTGLGLSIVKRLLGLFGSTITLESDLGAGTAFSFVIPFEHDPQKTKKIIEDIEVDL
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCE
TSSEIYKILIVEDNLINQLVTKKIIEKNNFVCKVVDDGFGALTILEKERFDLILMDINMP
ECCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCEEEEECCCH
LMNGFEATKRIRLLGVKTPIVALTAFDKDEITDEALSSGMNDIIVKPFEPVKLFKIINYL
HHCCHHHHHEEEEEEECCCEEEEEECCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
IIEAKNAGF
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA