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The map label for this gene is nccB [H]

Identifier: 146302192

GI number: 146302192

Start: 5383142

End: 5384317

Strand: Direct

Name: nccB [H]

Synonym: Fjoh_4463

Alternate gene names: 146302192

Gene position: 5383142-5384317 (Clockwise)

Preceding gene: 146302191

Following gene: 146302193

Centisome position: 88.29

GC content: 41.07

Gene sequence:

>1176_bases
ATGACAATGTATTCATTCGATATAAAAAATAAAAACCGGGGCAAGCTGAAAATACTGCTCCCCGTTCTGGGAATATTGTT
GCTGGTTCAATGCCAAAACAAGCCTAAAGAAGATGTTAAACAAACTGTTGTAAATGAAAGCAATACCGTAGTATTAACGG
ATGCCCAATTAAAAAATGCGGCTGTTGAAACGGTACGCCTTTCAGAAAAAAATATTGCTGCTGTTTTAAAATTAAACGGA
AAAATTGACGTGCCGCCGCAAAACCTGATTTCGGTAAGTGTGCCTTTGGGCGGTTTTTTGAAGAGCACCCGCTTACTGCC
CGGAATGTATGTGCGCAAAGGGGAAACTATTGCCGTGATGGAAGACCCGCAGTATATAAAACTGCAACAGGACTATTTGC
AGGCCAAATCAAAACTGCACTTTGCGCAGCTGGATTACCAGCGACAAAAAGACCTCAACCAAAGCCAGGCCAGCAGCGAT
AAGGTAATGCAGACGGCACAGGCAGAAGTGAGTAACCAGCAGATTATGATGAATGCCCTGGCACAGCAATTACGCCTTGT
CAACATCAATCCCAATAGCCTGAATGCGAATAAAATCACTAAAACCATTCCGGTTTACAGCACGATCAATGGCTTTGTAA
GCAAGGTAAATGTGAACATCGGGAAATATGTAAATCCTTCAGACATATTATTTGAATTAGTCAATCCCAACGATTTGCAC
CTCAATTTGAAAGTTTATGAAAACGACATAGATAAACTAAAAATCGGGCAAAAACTAATGGCCTATTCCAATGCAGAACC
CGGCAAAAAATACGAAGGGGAAATCATCCTTATCAGCAAAGACATCAGCAGCGATGGTATTTCGGAAGTGCATTGTCATT
TTGACCCCTATAACAAAAGCCTGTTGCCGGGCATGTACATGAATGCCGAAATAGAAACCAAAATCTCGTTCGCTCATGCC
GTTCCGGAAGAAAGCATCGTGAATTTTGAGGGAAAGGATTATGTGTTTGTGCAAACCGCCAGACAAACCTATAAAATGCT
GCCCATAACTGTAGGCGGGAAAGAAAACGGCTTTGTCCAGATTGTAAATGATGCAGATTTTACAGATAAAAACATCGTTT
CCAAAAATGCCTATACGCTCTTAATGAAACTAAAAAATACGGAAGATGAAGAGTAA

Upstream 100 bases:

>100_bases
GCTCATAAATCAAGCCATCAGTATTCAAAGTAATTACGCTGATGCTGTCAAAATGCTGAACGATACTATTATACAAATCA
ATTATCTCAATTAAATTCTT

Downstream 100 bases:

>100_bases
AGACAATTTTTTAGTGGGCAGAGCAAAAAGCTTGGTTTTTACATTAAAAGGAGCTTGGTATTTACTCACAACCGAAGATG
CTGCGAAGGCTCAATTTTTT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTMYSFDIKNKNRGKLKILLPVLGILLLVQCQNKPKEDVKQTVVNESNTVVLTDAQLKNAAVETVRLSEKNIAAVLKLNG
KIDVPPQNLISVSVPLGGFLKSTRLLPGMYVRKGETIAVMEDPQYIKLQQDYLQAKSKLHFAQLDYQRQKDLNQSQASSD
KVMQTAQAEVSNQQIMMNALAQQLRLVNINPNSLNANKITKTIPVYSTINGFVSKVNVNIGKYVNPSDILFELVNPNDLH
LNLKVYENDIDKLKIGQKLMAYSNAEPGKKYEGEIILISKDISSDGISEVHCHFDPYNKSLLPGMYMNAEIETKISFAHA
VPEESIVNFEGKDYVFVQTARQTYKMLPITVGGKENGFVQIVNDADFTDKNIVSKNAYTLLMKLKNTEDEE

Sequences:

>Translated_391_residues
MTMYSFDIKNKNRGKLKILLPVLGILLLVQCQNKPKEDVKQTVVNESNTVVLTDAQLKNAAVETVRLSEKNIAAVLKLNG
KIDVPPQNLISVSVPLGGFLKSTRLLPGMYVRKGETIAVMEDPQYIKLQQDYLQAKSKLHFAQLDYQRQKDLNQSQASSD
KVMQTAQAEVSNQQIMMNALAQQLRLVNINPNSLNANKITKTIPVYSTINGFVSKVNVNIGKYVNPSDILFELVNPNDLH
LNLKVYENDIDKLKIGQKLMAYSNAEPGKKYEGEIILISKDISSDGISEVHCHFDPYNKSLLPGMYMNAEIETKISFAHA
VPEESIVNFEGKDYVFVQTARQTYKMLPITVGGKENGFVQIVNDADFTDKNIVSKNAYTLLMKLKNTEDEE
>Mature_390_residues
TMYSFDIKNKNRGKLKILLPVLGILLLVQCQNKPKEDVKQTVVNESNTVVLTDAQLKNAAVETVRLSEKNIAAVLKLNGK
IDVPPQNLISVSVPLGGFLKSTRLLPGMYVRKGETIAVMEDPQYIKLQQDYLQAKSKLHFAQLDYQRQKDLNQSQASSDK
VMQTAQAEVSNQQIMMNALAQQLRLVNINPNSLNANKITKTIPVYSTINGFVSKVNVNIGKYVNPSDILFELVNPNDLHL
NLKVYENDIDKLKIGQKLMAYSNAEPGKKYEGEIILISKDISSDGISEVHCHFDPYNKSLLPGMYMNAEIETKISFAHAV
PEESIVNFEGKDYVFVQTARQTYKMLPITVGGKENGFVQIVNDADFTDKNIVSKNAYTLLMKLKNTEDEE

Specific function: Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43847; Mature: 43716

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMYSFDIKNKNRGKLKILLPVLGILLLVQCQNKPKEDVKQTVVNESNTVVLTDAQLKNA
CCEEEEECCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCHHCCH
AVETVRLSEKNIAAVLKLNGKIDVPPQNLISVSVPLGGFLKSTRLLPGMYVRKGETIAVM
HEEEEEECCCCEEEEEEECCEECCCCCCEEEEECCCCHHHHHHHCCCCEEEECCCEEEEE
EDPQYIKLQQDYLQAKSKLHFAQLDYQRQKDLNQSQASSDKVMQTAQAEVSNQQIMMNAL
ECCCEEEEHHHHHHHHHCEEHHHHCCHHHHCCCHHHCCHHHHHHHHHHHHCCHHHHHHHH
AQQLRLVNINPNSLNANKITKTIPVYSTINGFVSKVNVNIGKYVNPSDILFELVNPNDLH
HHHEEEEEECCCCCCCCHHEEEECHHHHHHHEHEEEEECCCCCCCCCHHEEEECCCCEEE
LNLKVYENDIDKLKIGQKLMAYSNAEPGKKYEGEIILISKDISSDGISEVHCHFDPYNKS
EEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCC
LLPGMYMNAEIETKISFAHAVPEESIVNFEGKDYVFVQTARQTYKMLPITVGGKENGFVQ
CCCCEEECCEEEEEEEEECCCCCCCEEECCCCCEEEEEECCCCEEEEEEEECCCCCCEEE
IVNDADFTDKNIVSKNAYTLLMKLKNTEDEE
EECCCCCCCCHHCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
TMYSFDIKNKNRGKLKILLPVLGILLLVQCQNKPKEDVKQTVVNESNTVVLTDAQLKNA
CEEEEECCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCHHCCH
AVETVRLSEKNIAAVLKLNGKIDVPPQNLISVSVPLGGFLKSTRLLPGMYVRKGETIAVM
HEEEEEECCCCEEEEEEECCEECCCCCCEEEEECCCCHHHHHHHCCCCEEEECCCEEEEE
EDPQYIKLQQDYLQAKSKLHFAQLDYQRQKDLNQSQASSDKVMQTAQAEVSNQQIMMNAL
ECCCEEEEHHHHHHHHHCEEHHHHCCHHHHCCCHHHCCHHHHHHHHHHHHCCHHHHHHHH
AQQLRLVNINPNSLNANKITKTIPVYSTINGFVSKVNVNIGKYVNPSDILFELVNPNDLH
HHHEEEEEECCCCCCCCHHEEEECHHHHHHHEHEEEEECCCCCCCCCHHEEEECCCCEEE
LNLKVYENDIDKLKIGQKLMAYSNAEPGKKYEGEIILISKDISSDGISEVHCHFDPYNKS
EEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCC
LLPGMYMNAEIETKISFAHAVPEESIVNFEGKDYVFVQTARQTYKMLPITVGGKENGFVQ
CCCCEEECCEEEEEEEEECCCCCCCEEECCCCCEEEEEECCCCEEEEEEEECCCCCCEEE
IVNDADFTDKNIVSKNAYTLLMKLKNTEDEE
EECCCCCCCCHHCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]