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The map label for this gene is ybbO [C]

Identifier: 146302144

GI number: 146302144

Start: 5321986

End: 5322981

Strand: Direct

Name: ybbO [C]

Synonym: Fjoh_4410

Alternate gene names: 146302144

Gene position: 5321986-5322981 (Clockwise)

Preceding gene: 146302143

Following gene: 146302145

Centisome position: 87.29

GC content: 42.07

Gene sequence:

>996_bases
ATGGAACAGAATAATTATCATGGAAAATTACAGAAAGCCACAGGTTCGGGATTTGGCGCAAAATCTACCTCAAAGGAAAT
TATAAAAGGAATTGACCTTATTGGGAAAACTGCCATTGTAACGGGCGGCAATACAGGCATTGGCATGGAAACCGTCAAAA
CACTTGCAGCAGCAGGCGCAGTTGTCATTGTGCCGGCCAGAGATGCAGAGAAAGCGAAAAGAAATCTCGAGGGAACTGCC
AATGTAATAATAGAAAAAATGGATTTAATGGATCCTGGTTCTATTGATGCTTTTACTGAAAAGTTTCTGCTTTCAGGAAG
AACGCTTCATCTGCTCATTAACAATGCAGGGATAATGTGGGTGCCGCTGCGCAGGGATTCTCGAGGCTATGAATCGCAGC
TGGCCACCAATTATCTGGCGCTGTTTCAGCTCACGGCAAGATTATGGCCTGCATTAAAAAAAGCAGATGGCGCCAGGGTG
GTAAATGTATCTTCCGGCGGACATCAATTTTCAGATTTTGATTTTCAAGATCCTAATTTCCTAAATAGGGAGTATGAGAC
CTTACAGGGATACGGACAGTCAAAAACTGCGGTGAATCTTTTTTCACTGGAATTAGACAATCGTGCAAAAAAGTATAATG
TGCGAAGCTATTCCTTATGCCCGGGTGCTGTGGGAGAAACTGAATTAGCGCGAGAAGCGCCAATTGACCTGTTCCAAAAA
CTGGGTTACAGTGATGCTGAGGGAAATATACTGCCGGAAGTAGCAGCTTCATTAAAAACGATTCCGCAAGGTGCAGCCAC
AACGCTTTGGGCAGCGACAAGCAAATCGCTTAACAATATTGGCGGGGTGTATTGTGAAAATGCAGATATAGCATCTTTAA
ATTCAAATGAAAAAATTATTGGAGGCGTTAAAGCTTATTCATTAGATGAAAAAAATGCAAAACGTTTATGGAAATTAAGC
CAGGAGATGACCGGAATAAATTTCGATCTTAGTTAA

Upstream 100 bases:

>100_bases
ACCTGGACGTTTAAACAAACCATAATAAGACGTTTGAACAAAGCTGCTGTTCCCCGCATCATCTAATTTTGTCCTGTTAA
AATAATTTAAATTAAAAAAA

Downstream 100 bases:

>100_bases
TATTTGTATCTTTATACCACACAGGCAATTATGGATTATCAGGTAAATTACATAAACCCAGACATTAAACTTTCTAATTA
TTCCGGTAAGCTGTTTAAAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEQNNYHGKLQKATGSGFGAKSTSKEIIKGIDLIGKTAIVTGGNTGIGMETVKTLAAAGAVVIVPARDAEKAKRNLEGTA
NVIIEKMDLMDPGSIDAFTEKFLLSGRTLHLLINNAGIMWVPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARV
VNVSSGGHQFSDFDFQDPNFLNREYETLQGYGQSKTAVNLFSLELDNRAKKYNVRSYSLCPGAVGETELAREAPIDLFQK
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKIIGGVKAYSLDEKNAKRLWKLS
QEMTGINFDLS

Sequences:

>Translated_331_residues
MEQNNYHGKLQKATGSGFGAKSTSKEIIKGIDLIGKTAIVTGGNTGIGMETVKTLAAAGAVVIVPARDAEKAKRNLEGTA
NVIIEKMDLMDPGSIDAFTEKFLLSGRTLHLLINNAGIMWVPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARV
VNVSSGGHQFSDFDFQDPNFLNREYETLQGYGQSKTAVNLFSLELDNRAKKYNVRSYSLCPGAVGETELAREAPIDLFQK
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKIIGGVKAYSLDEKNAKRLWKLS
QEMTGINFDLS
>Mature_331_residues
MEQNNYHGKLQKATGSGFGAKSTSKEIIKGIDLIGKTAIVTGGNTGIGMETVKTLAAAGAVVIVPARDAEKAKRNLEGTA
NVIIEKMDLMDPGSIDAFTEKFLLSGRTLHLLINNAGIMWVPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARV
VNVSSGGHQFSDFDFQDPNFLNREYETLQGYGQSKTAVNLFSLELDNRAKKYNVRSYSLCPGAVGETELAREAPIDLFQK
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKIIGGVKAYSLDEKNAKRLWKLS
QEMTGINFDLS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI166795268, Length=305, Percent_Identity=34.4262295081967, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI186928839, Length=306, Percent_Identity=34.3137254901961, Blast_Score=146, Evalue=2e-35,
Organism=Homo sapiens, GI7706523, Length=327, Percent_Identity=30.5810397553517, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI225579078, Length=298, Percent_Identity=32.5503355704698, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI10190746, Length=314, Percent_Identity=30.8917197452229, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI193804850, Length=304, Percent_Identity=32.8947368421053, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI146231950, Length=308, Percent_Identity=30.1948051948052, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI19923931, Length=261, Percent_Identity=29.5019157088123, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4504503, Length=200, Percent_Identity=30.5, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786701, Length=146, Percent_Identity=34.9315068493151, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193207620, Length=325, Percent_Identity=27.6923076923077, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71992402, Length=315, Percent_Identity=31.7460317460317, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17535059, Length=326, Percent_Identity=30.6748466257669, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17532805, Length=322, Percent_Identity=28.2608695652174, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17505416, Length=317, Percent_Identity=28.391167192429, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17532791, Length=334, Percent_Identity=27.5449101796407, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17558006, Length=309, Percent_Identity=30.42071197411, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32565532, Length=238, Percent_Identity=29.8319327731092, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324820, Length=277, Percent_Identity=31.4079422382672, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19921754, Length=308, Percent_Identity=35.7142857142857, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI161076371, Length=262, Percent_Identity=38.5496183206107, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573296, Length=299, Percent_Identity=36.7892976588629, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI22024069, Length=311, Percent_Identity=35.3697749196142, Blast_Score=130, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24586328, Length=321, Percent_Identity=33.0218068535826, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129347, Length=325, Percent_Identity=26.7692307692308, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24656154, Length=279, Percent_Identity=30.1075268817204, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI19922628, Length=279, Percent_Identity=30.1075268817204, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24647946, Length=304, Percent_Identity=30.5921052631579, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45553409, Length=303, Percent_Identity=30.6930693069307, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647948, Length=303, Percent_Identity=30.6930693069307, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45554248, Length=205, Percent_Identity=37.0731707317073, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640117, Length=205, Percent_Identity=37.0731707317073, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647931, Length=283, Percent_Identity=25.7950530035336, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35834; Mature: 35834

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNNYHGKLQKATGSGFGAKSTSKEIIKGIDLIGKTAIVTGGNTGIGMETVKTLAAAGA
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCC
VVIVPARDAEKAKRNLEGTANVIIEKMDLMDPGSIDAFTEKFLLSGRTLHLLINNAGIMW
EEEEECCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEEE
VPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARVVNVSSGGHQFSDFDFQDPNF
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
LNREYETLQGYGQSKTAVNLFSLELDNRAKKYNVRSYSLCPGAVGETELAREAPIDLFQK
CCHHHHHHHCCCCCCCEEEEEEEEECCCCHHCCCCEEECCCCCCCCHHHHHHCCHHHHHH
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKII
CCCCCCCCCCCHHHHHHHHHCCCCCHHEEHHHHHHHHHHCCCEEECCCCEECCCCCCEEE
GGVKAYSLDEKNAKRLWKLSQEMTGINFDLS
ECEEEECCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEQNNYHGKLQKATGSGFGAKSTSKEIIKGIDLIGKTAIVTGGNTGIGMETVKTLAAAGA
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCC
VVIVPARDAEKAKRNLEGTANVIIEKMDLMDPGSIDAFTEKFLLSGRTLHLLINNAGIMW
EEEEECCCHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEEE
VPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARVVNVSSGGHQFSDFDFQDPNF
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
LNREYETLQGYGQSKTAVNLFSLELDNRAKKYNVRSYSLCPGAVGETELAREAPIDLFQK
CCHHHHHHHCCCCCCCEEEEEEEEECCCCHHCCCCEEECCCCCCCCHHHHHHCCHHHHHH
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKII
CCCCCCCCCCCHHHHHHHHHCCCCCHHEEHHHHHHHHHHCCCEEECCCCEECCCCCCEEE
GGVKAYSLDEKNAKRLWKLSQEMTGINFDLS
ECEEEECCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]