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The map label for this gene is cusC [H]

Identifier: 146302037

GI number: 146302037

Start: 5199399

End: 5200817

Strand: Direct

Name: cusC [H]

Synonym: Fjoh_4301

Alternate gene names: 146302037

Gene position: 5199399-5200817 (Clockwise)

Preceding gene: 146302036

Following gene: 146302038

Centisome position: 85.28

GC content: 37.49

Gene sequence:

>1419_bases
ATGAAAAATCATATAACCAAAATCGTGACCTTCGCCATTCTGATCACGACTTTAATATCCTGTAAAGTCTCAAAGGATAT
TGAAACTCCAAAAGATGCATTTCCTGAGAATTTCAGGAATGCATCGGTTTCGAGTGATACAACCAGTATTGCCGATGTGG
AGTGGAAAAACTTCTTTACAGAAAAAGATATTATAAAATTAATTGACAGCGCCGTTGCAAGAAACAACGACCTTCAGATT
GCCGAAAAGAACATCGAAATTGCCCAATACCGTTTTACACAATCAAAATGGGGAAATGTGCCTCAGGTTAACTTATTTGT
AAACGCAAGCACAAGCAATCCGTCTGACAATAGTTTTACGGGATTGAACTTAAATCAAGCAATTGGTGCTAAACATATTG
ACGACTATTCTGCTGGAGCTTCTCTTTCTTGGGAAGCTGATATTTGGGGAAAGATCAGAAACCAAAAGAAAGGGGCTTAC
GCAGGATATCTTCAATCTGAAGAAGTAAAAAAAGCATTGCAGACTAATATTGTCGCTAATGTTTCTAGAGGATATTATAA
TCTTTTGATGCTGGATGCGCAATTGGATATTGCCAGACAAAATCTTCGTTTAAATGATAGTACAACCAATATTATCAAAT
TAAAATACGATGCCGGTCAGGTAACTACTTTAGCAATTCAACAATCGGAAGCACAGAAATTAAACTCAGCGCAATTGATT
CCGTTATTGGAACAAAATATTGCCATTCAGGAAAATGCTTTGAGTGTTTTAACAGGTTCTTTTCCAAATTCAAAAGAAAG
ATCTACTCAATTAAGTGCGATTGAAGTAAAACACAATACAGCAATTGGAGTTCCATCTGCCTTAGTAAGCAGAAGACCTG
ATGTAAAAAGTGCCGAATTGGCGCTAAAAGCTGCCAACGCAAATGTCGGTATCACGAAAGCGGATTTATACCCAGCTCTC
AGAATTACGGCTCAAGGCGGCGTAAACTCTTTCGAAACCAGTAATTGGTTCAACATTCCGGCTTCATTGTTTGGAACTGT
TGCGGGCGGATTAACGCAGCCTCTTTTAAATAACAAAAGAGTAAGAACGCAATATAATATCGCTGTCGCAGAAAGAGAAA
AAGCTGTTTTAAGTTTTAGACAATCTGTTTTGGTTGCTGTAAGCGAAGTTTCTGATGCTTTGGTTAAAGTAGAGAAATTA
CAACAGCAGGAAACTTTCTTAAAAGAAAAAGTAAAAACGCTGCAGCAAGCGATTAAAAATGCCAATCTTTTATTTAAAAA
TGGTATGGCAGAATATCTTGAAGTTTTAACGGCACAGGCAAATTTATTGCAAAGCGAACTAGAACTTGCTGATATCAAAA
GACAACAACTTACAGCCAATACAGATTTGTACCGCGCTCTAGGCGGAGGCTGGAAATAA

Upstream 100 bases:

>100_bases
TAAAATAAGTGAAACGCCTTTTTTAAATCCTCAAAAAACTATGTTTCTATGTGTTTAAAAAACTAAACCCAACGGATAAA
AAAATTTAATAAAAAACTAA

Downstream 100 bases:

>100_bases
TACCCGTTACATTACCCGTTAATTATTTATTTTTTGAGATGAAAACGCTGTGAGACCTTTGGGTTTCATGGCGTTTTTTA
GTTTAATTTTACTGAAGAAC

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKNHITKIVTFAILITTLISCKVSKDIETPKDAFPENFRNASVSSDTTSIADVEWKNFFTEKDIIKLIDSAVARNNDLQI
AEKNIEIAQYRFTQSKWGNVPQVNLFVNASTSNPSDNSFTGLNLNQAIGAKHIDDYSAGASLSWEADIWGKIRNQKKGAY
AGYLQSEEVKKALQTNIVANVSRGYYNLLMLDAQLDIARQNLRLNDSTTNIIKLKYDAGQVTTLAIQQSEAQKLNSAQLI
PLLEQNIAIQENALSVLTGSFPNSKERSTQLSAIEVKHNTAIGVPSALVSRRPDVKSAELALKAANANVGITKADLYPAL
RITAQGGVNSFETSNWFNIPASLFGTVAGGLTQPLLNNKRVRTQYNIAVAEREKAVLSFRQSVLVAVSEVSDALVKVEKL
QQQETFLKEKVKTLQQAIKNANLLFKNGMAEYLEVLTAQANLLQSELELADIKRQQLTANTDLYRALGGGWK

Sequences:

>Translated_472_residues
MKNHITKIVTFAILITTLISCKVSKDIETPKDAFPENFRNASVSSDTTSIADVEWKNFFTEKDIIKLIDSAVARNNDLQI
AEKNIEIAQYRFTQSKWGNVPQVNLFVNASTSNPSDNSFTGLNLNQAIGAKHIDDYSAGASLSWEADIWGKIRNQKKGAY
AGYLQSEEVKKALQTNIVANVSRGYYNLLMLDAQLDIARQNLRLNDSTTNIIKLKYDAGQVTTLAIQQSEAQKLNSAQLI
PLLEQNIAIQENALSVLTGSFPNSKERSTQLSAIEVKHNTAIGVPSALVSRRPDVKSAELALKAANANVGITKADLYPAL
RITAQGGVNSFETSNWFNIPASLFGTVAGGLTQPLLNNKRVRTQYNIAVAEREKAVLSFRQSVLVAVSEVSDALVKVEKL
QQQETFLKEKVKTLQQAIKNANLLFKNGMAEYLEVLTAQANLLQSELELADIKRQQLTANTDLYRALGGGWK
>Mature_472_residues
MKNHITKIVTFAILITTLISCKVSKDIETPKDAFPENFRNASVSSDTTSIADVEWKNFFTEKDIIKLIDSAVARNNDLQI
AEKNIEIAQYRFTQSKWGNVPQVNLFVNASTSNPSDNSFTGLNLNQAIGAKHIDDYSAGASLSWEADIWGKIRNQKKGAY
AGYLQSEEVKKALQTNIVANVSRGYYNLLMLDAQLDIARQNLRLNDSTTNIIKLKYDAGQVTTLAIQQSEAQKLNSAQLI
PLLEQNIAIQENALSVLTGSFPNSKERSTQLSAIEVKHNTAIGVPSALVSRRPDVKSAELALKAANANVGITKADLYPAL
RITAQGGVNSFETSNWFNIPASLFGTVAGGLTQPLLNNKRVRTQYNIAVAEREKAVLSFRQSVLVAVSEVSDALVKVEKL
QQQETFLKEKVKTLQQAIKNANLLFKNGMAEYLEVLTAQANLLQSELELADIKRQQLTANTDLYRALGGGWK

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=475, Percent_Identity=27.1578947368421, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI2367348, Length=478, Percent_Identity=20.2928870292887, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51978; Mature: 51978

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHITKIVTFAILITTLISCKVSKDIETPKDAFPENFRNASVSSDTTSIADVEWKNFFT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCCCCCCCCCEEECCHHHHHCC
EKDIIKLIDSAVARNNDLQIAEKNIEIAQYRFTQSKWGNVPQVNLFVNASTSNPSDNSFT
HHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECHHHCCCCCEEEEEEEECCCCCCCCCEE
GLNLNQAIGAKHIDDYSAGASLSWEADIWGKIRNQKKGAYAGYLQSEEVKKALQTNIVAN
CCCCHHHHCCCCCCCCCCCCCCEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
VSRGYYNLLMLDAQLDIARQNLRLNDSTTNIIKLKYDAGQVTTLAIQQSEAQKLNSAQLI
HCCCEEEEEEEECHHHHHHHCCEECCCCCEEEEEEECCCCEEEEEEECHHHHHCCCCCCC
PLLEQNIAIQENALSVLTGSFPNSKERSTQLSAIEVKHNTAIGVPSALVSRRPDVKSAEL
HHHHCCCEEHHCCHHHEECCCCCCCHHCCCEEEEEEECCCCCCCCHHHHCCCCCCCCHHE
ALKAANANVGITKADLYPALRITAQGGVNSFETSNWFNIPASLFGTVAGGLTQPLLNNKR
EEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCE
VRTQYNIAVAEREKAVLSFRQSVLVAVSEVSDALVKVEKLQQQETFLKEKVKTLQQAIKN
EEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLLFKNGMAEYLEVLTAQANLLQSELELADIKRQQLTANTDLYRALGGGWK
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure
MKNHITKIVTFAILITTLISCKVSKDIETPKDAFPENFRNASVSSDTTSIADVEWKNFFT
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCCCCCCCCCEEECCHHHHHCC
EKDIIKLIDSAVARNNDLQIAEKNIEIAQYRFTQSKWGNVPQVNLFVNASTSNPSDNSFT
HHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECHHHCCCCCEEEEEEEECCCCCCCCCEE
GLNLNQAIGAKHIDDYSAGASLSWEADIWGKIRNQKKGAYAGYLQSEEVKKALQTNIVAN
CCCCHHHHCCCCCCCCCCCCCCEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
VSRGYYNLLMLDAQLDIARQNLRLNDSTTNIIKLKYDAGQVTTLAIQQSEAQKLNSAQLI
HCCCEEEEEEEECHHHHHHHCCEECCCCCEEEEEEECCCCEEEEEEECHHHHHCCCCCCC
PLLEQNIAIQENALSVLTGSFPNSKERSTQLSAIEVKHNTAIGVPSALVSRRPDVKSAEL
HHHHCCCEEHHCCHHHEECCCCCCCHHCCCEEEEEEECCCCCCCCHHHHCCCCCCCCHHE
ALKAANANVGITKADLYPALRITAQGGVNSFETSNWFNIPASLFGTVAGGLTQPLLNNKR
EEEECCCCCCEEECCCCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCE
VRTQYNIAVAEREKAVLSFRQSVLVAVSEVSDALVKVEKLQQQETFLKEKVKTLQQAIKN
EEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLLFKNGMAEYLEVLTAQANLLQSELELADIKRQQLTANTDLYRALGGGWK
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]