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The map label for this gene is ycgM [C]

Identifier: 146301856

GI number: 146301856

Start: 4952272

End: 4953126

Strand: Reverse

Name: ycgM [C]

Synonym: Fjoh_4120

Alternate gene names: 146301856

Gene position: 4953126-4952272 (Counterclockwise)

Preceding gene: 146301857

Following gene: 146301855

Centisome position: 81.24

GC content: 36.02

Gene sequence:

>855_bases
ATGAAATTAATACGTTTTGGAGAAATCGGAAAAGAAAAACCAGGAGTTTTAATTAATGAAAAAAGATATGATGTTTCTTC
TATCGTTTCAGACTTTAACGAAAGCTTTTTTGAAGATAATGGTTTAGAAAAATTACAAAAAGCATTAGAAAGCAATCCTT
CTTTGCCAGAAGTTGATGCGAGTATACGTTTGGGATCTCCGGTTGCGAGACCTTCAAAAATAATCTGTATCGGATTAAAT
TATGTGGATCACTGTAAAGAAACCAATGCTCCAATCCCTACAGAACCAATTATTTTCTTTAAATCAACAACTTCTTTATG
CGGACCGGATGATGATGTAATTATCCCTAAAAACAGTGTAAAAACCGACTGGGAAGTGGAGCTGGCATTTGTAGTAGGCA
AAAAAGCAAGTTATGTTGAAGAAGCAGAAGCTTTAGACTATGTTGCAGGTTATGCATTATTGAATGATTACAGCGAAAGA
GAATTTCAAATCGAGCGCGGCGGACAATGGGCAAAAGGAAAAGGATGCGATACATTTGCACCTCTTGGGCCATTTTTGGC
TACGAAAGATGAAGTAAAAGATGTTGATAATTTATCGATGTGGTTAAGCGTAAACGGTAAAAAATACCAAGACAGTAATA
CTTTAAACCTTGTATTCAAAATTCCTTATTTAGTACACTACTTAAGTCAGTTTATGACTTTGCTTCCTGGCGATATCATT
AGTACAGGAACGCCTCCGGGAGTTGGTTTGGGTATTAAACCAGATCCAATTTATTTGAAAGCAGGCGATGTTGTAGAACT
TGGAATTGAAGGTTTGGGAACAAGCAAACAGACTGCAGTTGCATATAAAAAGTAA

Upstream 100 bases:

>100_bases
CTTAGAATCTTAGCCGCTTAGTACCTCTAAAAAAAAACTTAGAACCTTAGCCTCTCAGCACCTTAGAACCTAAAAAATAA
TAATTAAAATATATAAGAAA

Downstream 100 bases:

>100_bases
TTATTAAGTCGTTGGGCATAATTTTTTAAACACATAGGAACATAGATTTTGTTTATCTAAAAAGACGTTTCACTTGCATT
AACAAACATAGCTATGTGTA

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKLIRFGEIGKEKPGVLINEKRYDVSSIVSDFNESFFEDNGLEKLQKALESNPSLPEVDASIRLGSPVARPSKIICIGLN
YVDHCKETNAPIPTEPIIFFKSTTSLCGPDDDVIIPKNSVKTDWEVELAFVVGKKASYVEEAEALDYVAGYALLNDYSER
EFQIERGGQWAKGKGCDTFAPLGPFLATKDEVKDVDNLSMWLSVNGKKYQDSNTLNLVFKIPYLVHYLSQFMTLLPGDII
STGTPPGVGLGIKPDPIYLKAGDVVELGIEGLGTSKQTAVAYKK

Sequences:

>Translated_284_residues
MKLIRFGEIGKEKPGVLINEKRYDVSSIVSDFNESFFEDNGLEKLQKALESNPSLPEVDASIRLGSPVARPSKIICIGLN
YVDHCKETNAPIPTEPIIFFKSTTSLCGPDDDVIIPKNSVKTDWEVELAFVVGKKASYVEEAEALDYVAGYALLNDYSER
EFQIERGGQWAKGKGCDTFAPLGPFLATKDEVKDVDNLSMWLSVNGKKYQDSNTLNLVFKIPYLVHYLSQFMTLLPGDII
STGTPPGVGLGIKPDPIYLKAGDVVELGIEGLGTSKQTAVAYKK
>Mature_284_residues
MKLIRFGEIGKEKPGVLINEKRYDVSSIVSDFNESFFEDNGLEKLQKALESNPSLPEVDASIRLGSPVARPSKIICIGLN
YVDHCKETNAPIPTEPIIFFKSTTSLCGPDDDVIIPKNSVKTDWEVELAFVVGKKASYVEEAEALDYVAGYALLNDYSER
EFQIERGGQWAKGKGCDTFAPLGPFLATKDEVKDVDNLSMWLSVNGKKYQDSNTLNLVFKIPYLVHYLSQFMTLLPGDII
STGTPPGVGLGIKPDPIYLKAGDVVELGIEGLGTSKQTAVAYKK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=234, Percent_Identity=49.1452991452991, Blast_Score=231, Evalue=4e-61,
Organism=Homo sapiens, GI40786394, Length=234, Percent_Identity=48.7179487179487, Blast_Score=224, Evalue=5e-59,
Organism=Homo sapiens, GI215422413, Length=202, Percent_Identity=38.1188118811881, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI66348062, Length=202, Percent_Identity=38.1188118811881, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=38.1188118811881, Blast_Score=144, Evalue=8e-35,
Organism=Escherichia coli, GI1787428, Length=181, Percent_Identity=37.0165745856354, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17557057, Length=201, Percent_Identity=35.3233830845771, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324161, Length=230, Percent_Identity=33.9130434782609, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28572127, Length=287, Percent_Identity=45.6445993031359, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24663695, Length=212, Percent_Identity=40.0943396226415, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=38.7254901960784, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 31206; Mature: 31206

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIRFGEIGKEKPGVLINEKRYDVSSIVSDFNESFFEDNGLEKLQKALESNPSLPEVDA
CCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC
SIRLGSPVARPSKIICIGLNYVDHCKETNAPIPTEPIIFFKSTTSLCGPDDDVIIPKNSV
EEEECCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCC
KTDWEVELAFVVGKKASYVEEAEALDYVAGYALLNDYSEREFQIERGGQWAKGKGCDTFA
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
PLGPFLATKDEVKDVDNLSMWLSVNGKKYQDSNTLNLVFKIPYLVHYLSQFMTLLPGDII
CCCCHHCCHHHHHCCCCEEEEEEECCCEECCCCEEEEEEEHHHHHHHHHHHHHHCCCCHH
STGTPPGVGLGIKPDPIYLKAGDVVELGIEGLGTSKQTAVAYKK
CCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCEEEECC
>Mature Secondary Structure
MKLIRFGEIGKEKPGVLINEKRYDVSSIVSDFNESFFEDNGLEKLQKALESNPSLPEVDA
CCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC
SIRLGSPVARPSKIICIGLNYVDHCKETNAPIPTEPIIFFKSTTSLCGPDDDVIIPKNSV
EEEECCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCC
KTDWEVELAFVVGKKASYVEEAEALDYVAGYALLNDYSEREFQIERGGQWAKGKGCDTFA
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
PLGPFLATKDEVKDVDNLSMWLSVNGKKYQDSNTLNLVFKIPYLVHYLSQFMTLLPGDII
CCCCHHCCHHHHHCCCCEEEEEEECCCEECCCCEEEEEEEHHHHHHHHHHHHHHCCCCHH
STGTPPGVGLGIKPDPIYLKAGDVVELGIEGLGTSKQTAVAYKK
CCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA