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The map label for this gene is yjjN [H]

Identifier: 146301855

GI number: 146301855

Start: 4951044

End: 4952114

Strand: Reverse

Name: yjjN [H]

Synonym: Fjoh_4119

Alternate gene names: 146301855

Gene position: 4952114-4951044 (Counterclockwise)

Preceding gene: 146301856

Following gene: 146301854

Centisome position: 81.22

GC content: 36.04

Gene sequence:

>1071_bases
ATGTGTTTAAAAAAAAAACGAATTGTACCCTACGAGTTAGTTTTAAAAAAATCAAAGATGAAATTTATTGTATGCGAAAA
ACCGCAGGAATTTAAATTAAAAGAAAAAGAAATTCCCGAACCAAAAGAAGGTGAGGTTCTTTTAAAAATAAAAAGAATTG
GTATCTGTGGAACTGATATTCATGCTTTTGGCGGAACCCAGCCGTATTTTGAATATCCTCGAATTCTGGGTCACGAATTG
GCAGCAGAATATGTAAAAGGAAATGCTGCAGGTTTTAAACCGGGCGATAAAGTAACTTTTATTCCATATTTCAACTGCGG
AACTTGTGTTGCCTGCCGAAACGGATTAACAAACTGCTGTGTAAATATCAAAGTTTTTGGAGTTCATATTGATGGCGGAA
TGGCCGAATATGTTTCGATTCCGGAACAATATTTACTTCACGGTCAGGGATTAGATTATGATGAACTGGCTTTGGTTGAA
CCATTGGCAATTGCTGCGCACGGAGTACGAAGAGCGGCTGTTAAGTCAACTGATACGGTTTTGGTAATGGGAGCAGGGCC
AATTGGAATTGGACTGATTCAGTTTGCTAAAATTGCCGGAGCAAAAGTGATCGTAATGGATATCAACGATTACAGATTAA
ATTTCTGTAAAACCGAATTGAATGCCGATGAAACCATCAATCCGTTAAACGATGATGTAGCCGCAAAATTGGCTGAATTG
ACAAACGGTGATATGGCAAATGTGGTAATTGATGCTACAGGAAACCAAAAAGTAATGAACAGTGCTTTCAATTATATTTC
GCATGGCGGAAGATTTGTTTTAGTGGGGCTTCAAAAAGGTGAATTGAGTTTCAGTCATCCTGATTTTCATAAAAGAGAAT
CTACTTTAATGAGCAGCCGAAATGCCACTATTGAAGATTTTGAATATGTAATGAAATGCTTGAAAGAAGGTAAAATAGAT
CCTAAAAAATACATTACGCACAGAACAAGTTTCTCAGAAATGATTACTGATTTTGGACAATTAATTGATCCTAAAAACAA
TGTAATCAAAGCGTTAATTGAGATAGATTAA

Upstream 100 bases:

>100_bases
TAAAAAGACGTTTCACTTGCATTAACAAACATAGCTATGTGTAAATGATGTATCATTTATTTTAGTTTTCTTGTTTAAAA
AGGAAAAAATCTATGTTTCT

Downstream 100 bases:

>100_bases
GAGTATATTGTAAAGTACTGTTTGTCATTTCGACGAAGGAGAAATCTTCGCAAGAAACTCTACAAAGATTGTCGAATTTC
TAGATGGAGCTTCTCGCGGA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MCLKKKRIVPYELVLKKSKMKFIVCEKPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDIHAFGGTQPYFEYPRILGHEL
AAEYVKGNAAGFKPGDKVTFIPYFNCGTCVACRNGLTNCCVNIKVFGVHIDGGMAEYVSIPEQYLLHGQGLDYDELALVE
PLAIAAHGVRRAAVKSTDTVLVMGAGPIGIGLIQFAKIAGAKVIVMDINDYRLNFCKTELNADETINPLNDDVAAKLAEL
TNGDMANVVIDATGNQKVMNSAFNYISHGGRFVLVGLQKGELSFSHPDFHKRESTLMSSRNATIEDFEYVMKCLKEGKID
PKKYITHRTSFSEMITDFGQLIDPKNNVIKALIEID

Sequences:

>Translated_356_residues
MCLKKKRIVPYELVLKKSKMKFIVCEKPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDIHAFGGTQPYFEYPRILGHEL
AAEYVKGNAAGFKPGDKVTFIPYFNCGTCVACRNGLTNCCVNIKVFGVHIDGGMAEYVSIPEQYLLHGQGLDYDELALVE
PLAIAAHGVRRAAVKSTDTVLVMGAGPIGIGLIQFAKIAGAKVIVMDINDYRLNFCKTELNADETINPLNDDVAAKLAEL
TNGDMANVVIDATGNQKVMNSAFNYISHGGRFVLVGLQKGELSFSHPDFHKRESTLMSSRNATIEDFEYVMKCLKEGKID
PKKYITHRTSFSEMITDFGQLIDPKNNVIKALIEID
>Mature_356_residues
MCLKKKRIVPYELVLKKSKMKFIVCEKPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDIHAFGGTQPYFEYPRILGHEL
AAEYVKGNAAGFKPGDKVTFIPYFNCGTCVACRNGLTNCCVNIKVFGVHIDGGMAEYVSIPEQYLLHGQGLDYDELALVE
PLAIAAHGVRRAAVKSTDTVLVMGAGPIGIGLIQFAKIAGAKVIVMDINDYRLNFCKTELNADETINPLNDDVAAKLAEL
TNGDMANVVIDATGNQKVMNSAFNYISHGGRFVLVGLQKGELSFSHPDFHKRESTLMSSRNATIEDFEYVMKCLKEGKID
PKKYITHRTSFSEMITDFGQLIDPKNNVIKALIEID

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=336, Percent_Identity=28.2738095238095, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI71565154, Length=358, Percent_Identity=27.3743016759777, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4501939, Length=289, Percent_Identity=25.9515570934256, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI156523966, Length=276, Percent_Identity=26.0869565217391, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4501929, Length=252, Percent_Identity=30.952380952381, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI262073058, Length=295, Percent_Identity=29.4915254237288, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI71743840, Length=295, Percent_Identity=29.4915254237288, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI226510992, Length=338, Percent_Identity=47.6331360946746, Blast_Score=315, Evalue=4e-87,
Organism=Escherichia coli, GI1787863, Length=321, Percent_Identity=35.202492211838, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1788073, Length=353, Percent_Identity=28.8951841359773, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1790045, Length=327, Percent_Identity=28.7461773700306, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87082125, Length=318, Percent_Identity=30.5031446540881, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788075, Length=340, Percent_Identity=26.4705882352941, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790718, Length=298, Percent_Identity=27.8523489932886, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788407, Length=326, Percent_Identity=26.9938650306748, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=30.6748466257669, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786552, Length=355, Percent_Identity=28.7323943661972, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786825, Length=368, Percent_Identity=23.3695652173913, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=259, Percent_Identity=33.976833976834, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17562878, Length=245, Percent_Identity=30.6122448979592, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17562584, Length=263, Percent_Identity=29.277566539924, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562582, Length=323, Percent_Identity=27.2445820433437, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=266, Percent_Identity=26.6917293233083, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25146526, Length=347, Percent_Identity=25.0720461095101, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997431, Length=349, Percent_Identity=24.6418338108883, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=346, Percent_Identity=29.7687861271676, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319955, Length=346, Percent_Identity=29.7687861271676, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320033, Length=355, Percent_Identity=27.3239436619718, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323099, Length=345, Percent_Identity=27.2463768115942, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319257, Length=359, Percent_Identity=27.5766016713092, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319258, Length=362, Percent_Identity=26.2430939226519, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=272, Percent_Identity=27.9411764705882, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=278, Percent_Identity=27.6978417266187, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=277, Percent_Identity=27.0758122743682, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=279, Percent_Identity=26.1648745519713, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737897, Length=339, Percent_Identity=28.3185840707965, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17137530, Length=339, Percent_Identity=28.6135693215339, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17737895, Length=318, Percent_Identity=27.3584905660377, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221457811, Length=324, Percent_Identity=23.1481481481481, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550770, Length=324, Percent_Identity=23.1481481481481, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551930, Length=312, Percent_Identity=23.3974358974359, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 39430; Mature: 39430

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLKKKRIVPYELVLKKSKMKFIVCEKPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDI
CCCCCCCCCCHHHHEECCCEEEEEECCCCCCCCHHHCCCCCCCCCEEEEEEEECEECCCC
HAFGGTQPYFEYPRILGHELAAEYVKGNAAGFKPGDKVTFIPYFNCGTCVACRNGLTNCC
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHCCCCCEE
VNIKVFGVHIDGGMAEYVSIPEQYLLHGQGLDYDELALVEPLAIAAHGVRRAAVKSTDTV
EEEEEEEEEECCCHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVMGAGPIGIGLIQFAKIAGAKVIVMDINDYRLNFCKTELNADETINPLNDDVAAKLAEL
EEEECCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
TNGDMANVVIDATGNQKVMNSAFNYISHGGRFVLVGLQKGELSFSHPDFHKRESTLMSSR
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCC
NATIEDFEYVMKCLKEGKIDPKKYITHRTSFSEMITDFGQLIDPKNNVIKALIEID
CCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHEEEEEECC
>Mature Secondary Structure
MCLKKKRIVPYELVLKKSKMKFIVCEKPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDI
CCCCCCCCCCHHHHEECCCEEEEEECCCCCCCCHHHCCCCCCCCCEEEEEEEECEECCCC
HAFGGTQPYFEYPRILGHELAAEYVKGNAAGFKPGDKVTFIPYFNCGTCVACRNGLTNCC
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHCCCCCEE
VNIKVFGVHIDGGMAEYVSIPEQYLLHGQGLDYDELALVEPLAIAAHGVRRAAVKSTDTV
EEEEEEEEEECCCHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LVMGAGPIGIGLIQFAKIAGAKVIVMDINDYRLNFCKTELNADETINPLNDDVAAKLAEL
EEEECCCHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
TNGDMANVVIDATGNQKVMNSAFNYISHGGRFVLVGLQKGELSFSHPDFHKRESTLMSSR
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCC
NATIEDFEYVMKCLKEGKIDPKKYITHRTSFSEMITDFGQLIDPKNNVIKALIEID
CCCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]