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The map label for this gene is fmt [H]

Identifier: 146301786

GI number: 146301786

Start: 4829975

End: 4830913

Strand: Direct

Name: fmt [H]

Synonym: Fjoh_4050

Alternate gene names: 146301786

Gene position: 4829975-4830913 (Clockwise)

Preceding gene: 146301785

Following gene: 146301787

Centisome position: 79.22

GC content: 34.4

Gene sequence:

>939_bases
ATGAATCCGATACGCGACATAGTAATTTTATGTAATAACCGTATGGCTTTTCCAGCTATACAAACTTTACATAGTCTTGG
AAGACTGCATACAATAGCTGTACCCGCCGAAAATGAAGACGTTAAAGCCTTTTGCTCTGTTTTTGCAACAAAAGCCGGCG
TAAATTTAATATGGATGGAGAAAGCAAAACTCAACATCCAGCTTCAGGAAATTTTGCGAATCAGCTCTTTAAAATATGTT
TTTACCATGACTTTCCCTTGGAAAATTCCAGGAGAAATTATTGAAAAACATCCTAATATGTTCTATAATTTTCATTATGG
ACTTTTACCTGAAATGCGTGGTGCAGATCCTGTTTTTGAATCGATTAGAAAACAAAAACAAGAAACCGGAATATCTGTAC
ATGCTATAGAGAAGGAAATAGATAAAGGAAAAATAATCCTAAAAAAAACAATGCCCCTGCATACTGATTTGACACATGGA
ATGCTTTGCACTAGTTTATCATATCTGGCTTCTTATATTCTGCCTGAATTATTAACCTTATTATCTATGAATGATAAAGG
TGTTCTTCAGGATGAAAACTTAGCTGCATATTATAAAAAACCAACTATCTCTGATGTGAGCATTCAATGGGAAAAACAGG
ACTCAAAATCAATCCAGGCATTAGTTAACGCCTGCAATCCGTGGAATAAAGGTGCTTATACACAATGGAATGGTCTCAAT
ATACGATTACTGGAGGTTTCACAAACCAATTCACCTTTAAGCAGCACAAAACCTCCGGGAACTATTTTAGAAATAGATGA
AAACAAAGGCTTAATAATACAATGTTATAATAATACACAACTTCGTATAAATACTGTTTATACAGAAGAAGGCTTTATGA
GTGGGCACAAATTGCTCGCTTTTGGTATAAAAAATGGCGAACAATTTGCCTCTTTATAA

Upstream 100 bases:

>100_bases
CTGATTTAGAAGAAGAACGCATCCGTTTATATCAACATATTCTGGCAGTTCAAAATACGCCTTCTAATTCCTGGTTAAAC
TCTTATGCCTGTTTAGACTC

Downstream 100 bases:

>100_bases
TTTAACTAACTTTATTATGAAACATTTTTACTCTCAAATTAAAAAATGCTTAAATATTGCCCTATTTTTAGGGATATTTT
TGCAGAGTTATTTAAGTAAC

Product: formyl transferase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNPIRDIVILCNNRMAFPAIQTLHSLGRLHTIAVPAENEDVKAFCSVFATKAGVNLIWMEKAKLNIQLQEILRISSLKYV
FTMTFPWKIPGEIIEKHPNMFYNFHYGLLPEMRGADPVFESIRKQKQETGISVHAIEKEIDKGKIILKKTMPLHTDLTHG
MLCTSLSYLASYILPELLTLLSMNDKGVLQDENLAAYYKKPTISDVSIQWEKQDSKSIQALVNACNPWNKGAYTQWNGLN
IRLLEVSQTNSPLSSTKPPGTILEIDENKGLIIQCYNNTQLRINTVYTEEGFMSGHKLLAFGIKNGEQFASL

Sequences:

>Translated_312_residues
MNPIRDIVILCNNRMAFPAIQTLHSLGRLHTIAVPAENEDVKAFCSVFATKAGVNLIWMEKAKLNIQLQEILRISSLKYV
FTMTFPWKIPGEIIEKHPNMFYNFHYGLLPEMRGADPVFESIRKQKQETGISVHAIEKEIDKGKIILKKTMPLHTDLTHG
MLCTSLSYLASYILPELLTLLSMNDKGVLQDENLAAYYKKPTISDVSIQWEKQDSKSIQALVNACNPWNKGAYTQWNGLN
IRLLEVSQTNSPLSSTKPPGTILEIDENKGLIIQCYNNTQLRINTVYTEEGFMSGHKLLAFGIKNGEQFASL
>Mature_312_residues
MNPIRDIVILCNNRMAFPAIQTLHSLGRLHTIAVPAENEDVKAFCSVFATKAGVNLIWMEKAKLNIQLQEILRISSLKYV
FTMTFPWKIPGEIIEKHPNMFYNFHYGLLPEMRGADPVFESIRKQKQETGISVHAIEKEIDKGKIILKKTMPLHTDLTHG
MLCTSLSYLASYILPELLTLLSMNDKGVLQDENLAAYYKKPTISDVSIQWEKQDSKSIQALVNACNPWNKGAYTQWNGLN
IRLLEVSQTNSPLSSTKPPGTILEIDENKGLIIQCYNNTQLRINTVYTEEGFMSGHKLLAFGIKNGEQFASL

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Escherichia coli, GI1788589, Length=314, Percent_Identity=23.8853503184713, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789683, Length=183, Percent_Identity=26.775956284153, Blast_Score=68, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45550868, Length=310, Percent_Identity=25.1612903225806, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571984, Length=277, Percent_Identity=26.3537906137184, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 35273; Mature: 35273

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIRDIVILCNNRMAFPAIQTLHSLGRLHTIAVPAENEDVKAFCSVFATKAGVNLIWME
CCCHHEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
KAKLNIQLQEILRISSLKYVFTMTFPWKIPGEIIEKHPNMFYNFHYGLLPEMRGADPVFE
CCCCCEEHHHHHHHHCEEEEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
SIRKQKQETGISVHAIEKEIDKGKIILKKTMPLHTDLTHGMLCTSLSYLASYILPELLTL
HHHHHHHHCCCEEEEEHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSMNDKGVLQDENLAAYYKKPTISDVSIQWEKQDSKSIQALVNACNPWNKGAYTQWNGLN
HCCCCCCCEECCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCE
IRLLEVSQTNSPLSSTKPPGTILEIDENKGLIIQCYNNTQLRINTVYTEEGFMSGHKLLA
EEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCEEEE
FGIKNGEQFASL
EEECCCHHHHCC
>Mature Secondary Structure
MNPIRDIVILCNNRMAFPAIQTLHSLGRLHTIAVPAENEDVKAFCSVFATKAGVNLIWME
CCCHHEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEE
KAKLNIQLQEILRISSLKYVFTMTFPWKIPGEIIEKHPNMFYNFHYGLLPEMRGADPVFE
CCCCCEEHHHHHHHHCEEEEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHHH
SIRKQKQETGISVHAIEKEIDKGKIILKKTMPLHTDLTHGMLCTSLSYLASYILPELLTL
HHHHHHHHCCCEEEEEHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSMNDKGVLQDENLAAYYKKPTISDVSIQWEKQDSKSIQALVNACNPWNKGAYTQWNGLN
HCCCCCCCEECCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEECCCE
IRLLEVSQTNSPLSSTKPPGTILEIDENKGLIIQCYNNTQLRINTVYTEEGFMSGHKLLA
EEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCEEEE
FGIKNGEQFASL
EEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA