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The map label for this gene is fucP [H]

Identifier: 146301780

GI number: 146301780

Start: 4824592

End: 4825854

Strand: Direct

Name: fucP [H]

Synonym: Fjoh_4044

Alternate gene names: 146301780

Gene position: 4824592-4825854 (Clockwise)

Preceding gene: 146301779

Following gene: 146301781

Centisome position: 79.13

GC content: 36.03

Gene sequence:

>1263_bases
ATGTCTCAGGCTAAATTCACAGAAAAAAAATATATTCTAACGCTTACTTTTGTAATCTCGCTTTTTCTTTTTTGGGCAAT
TGCAATCACGATGGGCGATGTTCTTAATAAACATTTTCAAAACGTACTGCATATCAGTAAATCAGAATCGGGTTTGGTGC
AGCTATCCATTTTTGGTGCTTATGCCGTAATGGGTATTCCGGCTGGTTTATTCATGAAAAAATACGGTTATAAAAACGGA
GTAATTCTAGGGTTGATTCTTTATGCATTTGGTGCTTTCCTTTTTATTCCGGCAGCTCAAAATGAATCTTTCTCTTATTT
CAGGATTGCATTATTTATTTTGGCTGCAGGTCTTGCAACGCTGGAAACTGTTGCACATCCTTTTGTTGCTTTACTGGGCG
ATGAACGCACAAGCGACCAGAGAATAAATTTTGCACAATCTTTTAATGGTTTGGGCGCTATAATAGGTCCGCTTCTTGGC
GGTTTCTTTATTCTCGATTCAAAAGGCGCCGAAGGTCTAGAATCTGTTAAAACCTTATATATGATTATTGGCAGTTTTAT
ACTTTTAATTGCCATTTTGTTTTGGTTTGTAAAAGTACCATCGCTTAAGGGCTCTCATAGTCACGAAGAACAAAGTACCG
ACGATGAAAATACAAACGTAGTTCCTGATTCGCCTTTGTACATGCAAAGACATTTTATATGGGCTGTAATTGCTCAGTTT
TTTAATATTGGAGCGCAGGGCGGTACGTGGGCTTATTTTATAAATTATGGTGTCGAAAAAACAGGTTTGGCTGATAATCA
GGTTGCTTATTATTTCTCTTTCAGCATGGCTATGATGATGATTGGCCGTTTTATTGGAACGTTTTTATTGCGCTATATTG
CTCCAAATAAACTATTAGCAATTTATTGTATGTGTAATATTGGGCTTTGTCTGGTTATTTCTCAAAGTTTTGGCTGGGTT
TCGTTTATTGCCTTAATTATGCTCAATTTTTTCTTAAGTGTAATGTACCCAACTATTTTCAGCCTCGGATTAAAAAAACT
TGGAAACAAAACAGAACAAGCTTCCTCTTTTTTAGTAATGGCAATGTTTGGCGGTGCAGTTTTTCCTCCAATTATGGGTT
TTGTGGCAAATACAAATGTGGCTTACGCCTATCTTTTACCTATAATATGTTATTTGGTAATTCTTGTATTTGCCATTAAA
TATTACAAACCACATACACTTGGACAGCCTTATGTACTTTCTAAAAGAGACATTGTGCGTTAA

Upstream 100 bases:

>100_bases
AAAAGGTGCCTGTCCAAGTTATGATTTAAATGACTTTGAACTTTTTAGAAAAGAAAATGAGGCTAAATAAAATGTATAAT
AGTAATAATGATTTGTAAAA

Downstream 100 bases:

>100_bases
ACTTTCAAAATAAAACATTCTTCTTCAAAAAATACACAATGAAAATAAAAATAGGCGCTTCACTCCTATCCTGGACAACT
CCAAACTGGACTCCGGAATC

Product: L-fucose transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSQAKFTEKKYILTLTFVISLFLFWAIAITMGDVLNKHFQNVLHISKSESGLVQLSIFGAYAVMGIPAGLFMKKYGYKNG
VILGLILYAFGAFLFIPAAQNESFSYFRIALFILAAGLATLETVAHPFVALLGDERTSDQRINFAQSFNGLGAIIGPLLG
GFFILDSKGAEGLESVKTLYMIIGSFILLIAILFWFVKVPSLKGSHSHEEQSTDDENTNVVPDSPLYMQRHFIWAVIAQF
FNIGAQGGTWAYFINYGVEKTGLADNQVAYYFSFSMAMMMIGRFIGTFLLRYIAPNKLLAIYCMCNIGLCLVISQSFGWV
SFIALIMLNFFLSVMYPTIFSLGLKKLGNKTEQASSFLVMAMFGGAVFPPIMGFVANTNVAYAYLLPIICYLVILVFAIK
YYKPHTLGQPYVLSKRDIVR

Sequences:

>Translated_420_residues
MSQAKFTEKKYILTLTFVISLFLFWAIAITMGDVLNKHFQNVLHISKSESGLVQLSIFGAYAVMGIPAGLFMKKYGYKNG
VILGLILYAFGAFLFIPAAQNESFSYFRIALFILAAGLATLETVAHPFVALLGDERTSDQRINFAQSFNGLGAIIGPLLG
GFFILDSKGAEGLESVKTLYMIIGSFILLIAILFWFVKVPSLKGSHSHEEQSTDDENTNVVPDSPLYMQRHFIWAVIAQF
FNIGAQGGTWAYFINYGVEKTGLADNQVAYYFSFSMAMMMIGRFIGTFLLRYIAPNKLLAIYCMCNIGLCLVISQSFGWV
SFIALIMLNFFLSVMYPTIFSLGLKKLGNKTEQASSFLVMAMFGGAVFPPIMGFVANTNVAYAYLLPIICYLVILVFAIK
YYKPHTLGQPYVLSKRDIVR
>Mature_419_residues
SQAKFTEKKYILTLTFVISLFLFWAIAITMGDVLNKHFQNVLHISKSESGLVQLSIFGAYAVMGIPAGLFMKKYGYKNGV
ILGLILYAFGAFLFIPAAQNESFSYFRIALFILAAGLATLETVAHPFVALLGDERTSDQRINFAQSFNGLGAIIGPLLGG
FFILDSKGAEGLESVKTLYMIIGSFILLIAILFWFVKVPSLKGSHSHEEQSTDDENTNVVPDSPLYMQRHFIWAVIAQFF
NIGAQGGTWAYFINYGVEKTGLADNQVAYYFSFSMAMMMIGRFIGTFLLRYIAPNKLLAIYCMCNIGLCLVISQSFGWVS
FIALIMLNFFLSVMYPTIFSLGLKKLGNKTEQASSFLVMAMFGGAVFPPIMGFVANTNVAYAYLLPIICYLVILVFAIKY
YKPHTLGQPYVLSKRDIVR

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=414, Percent_Identity=40.8212560386473, Blast_Score=295, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46724; Mature: 46593

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAKFTEKKYILTLTFVISLFLFWAIAITMGDVLNKHFQNVLHISKSESGLVQLSIFGA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
YAVMGIPAGLFMKKYGYKNGVILGLILYAFGAFLFIPAAQNESFSYFRIALFILAAGLAT
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHH
LETVAHPFVALLGDERTSDQRINFAQSFNGLGAIIGPLLGGFFILDSKGAEGLESVKTLY
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHH
MIIGSFILLIAILFWFVKVPSLKGSHSHEEQSTDDENTNVVPDSPLYMQRHFIWAVIAQF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FNIGAQGGTWAYFINYGVEKTGLADNQVAYYFSFSMAMMMIGRFIGTFLLRYIAPNKLLA
HHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IYCMCNIGLCLVISQSFGWVSFIALIMLNFFLSVMYPTIFSLGLKKLGNKTEQASSFLVM
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AMFGGAVFPPIMGFVANTNVAYAYLLPIICYLVILVFAIKYYKPHTLGQPYVLSKRDIVR
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
SQAKFTEKKYILTLTFVISLFLFWAIAITMGDVLNKHFQNVLHISKSESGLVQLSIFGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHH
YAVMGIPAGLFMKKYGYKNGVILGLILYAFGAFLFIPAAQNESFSYFRIALFILAAGLAT
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHH
LETVAHPFVALLGDERTSDQRINFAQSFNGLGAIIGPLLGGFFILDSKGAEGLESVKTLY
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHH
MIIGSFILLIAILFWFVKVPSLKGSHSHEEQSTDDENTNVVPDSPLYMQRHFIWAVIAQF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FNIGAQGGTWAYFINYGVEKTGLADNQVAYYFSFSMAMMMIGRFIGTFLLRYIAPNKLLA
HHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IYCMCNIGLCLVISQSFGWVSFIALIMLNFFLSVMYPTIFSLGLKKLGNKTEQASSFLVM
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AMFGGAVFPPIMGFVANTNVAYAYLLPIICYLVILVFAIKYYKPHTLGQPYVLSKRDIVR
HHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]