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The map label for this gene is lytS [H]

Identifier: 146301740

GI number: 146301740

Start: 4784608

End: 4785624

Strand: Reverse

Name: lytS [H]

Synonym: Fjoh_4002

Alternate gene names: 146301740

Gene position: 4785624-4784608 (Counterclockwise)

Preceding gene: 146301741

Following gene: 146301739

Centisome position: 78.49

GC content: 35.4

Gene sequence:

>1017_bases
ATGGAAAAAGCAAAACGTTTTCAGGTTTCGCTCAAAGTTATTTGGGGAAGTTCTATTGCGCTGGCAGTTATGGCTTCGAT
ACCTAAATTATTTGATGCCGATTCTACACCTGGAGACCTTATTATAAATTCTTCGATTACACTGCTGTTTTCTCTTTTTA
TATGGTATTACAACATTTACAGCTTACCTAAATTCTCATCACAGCGCACGAACAAAAGTCTGTTTAACTGGAAACTTTTG
CTTAGTGTTGTACTGGGAATTTTGCTGATGGTGATTCTCGTAATCGCACATCAGGAACTTTTTCAGGTTTCAAAAATGGA
TGCGCCTATTATGTTTGAACTCCGCGGGGTTTTAATCAATTTAATTGTCTATATGTTCCTGCATTTGCTTTTTCAAAATT
ATCAAACCCAGCAAATGGGAGTAGAACTGGAGCGTACCAAAGCTGTACATCTTGGAGCGCAGTATGAACTTTTGAAACAG
CAGGTCAATCCGCATTTTTTGTTTAACAGTCTAAATACTTTAAAATCGATGGTTGATATGCAGGATCCTCAGAGTTCTGA
TTTTATCCTGAAATTATCTGATTTTTATCGATTTACCCTAGAAAGCCGAAAAATGGATTTGATTCCGTTAAAAGAAGAAT
TGCAGATTCTGGATTCTTATGTATATCTGCTCAAAGCCCGTTTTGAAGATGGATTTGAAGTTATAAAAGAAATTGATGCC
CAGCAGTACGATTGTGCAATTCCGCCTTTTTCACTACAGTTATTGATCGAAAATTGTATCAAACACAATATCGTTTCGCT
TGATAAACCTTTGAAAATTAAATTATATACCGAAAATGATTTTCTGGTAATCGAAAACCCAATCCAGCTGAAACGAGGCA
CTTTGTCAACAGGCGTTGGACTGAACAATATCAATCAGCGATTCCTTCATTTGGTGAACAAAGAAATTGAAATTGACAAA
ACCGAAACCCATTTTAAAGTTAAAATACCACTAATTTATGACTATCATAATAATTGA

Upstream 100 bases:

>100_bases
AGAAATGGCAATACTCTGGGCTGACTTTTTAAATCTGCGTGAAAAGTTTTTTCAAAATAAACCTATCTTTGATTAACAGA
ATAACAAAACCACTATCATT

Downstream 100 bases:

>100_bases
AGATGAAGTAAAAACGGACAAAGCGCTTGGTCAGCTTATTTTGAGTATCAGACCCGATGCTCAGATTTTGTCGTATATTC
AAAGTATAGACGGTGCTGTG

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEKAKRFQVSLKVIWGSSIALAVMASIPKLFDADSTPGDLIINSSITLLFSLFIWYYNIYSLPKFSSQRTNKSLFNWKLL
LSVVLGILLMVILVIAHQELFQVSKMDAPIMFELRGVLINLIVYMFLHLLFQNYQTQQMGVELERTKAVHLGAQYELLKQ
QVNPHFLFNSLNTLKSMVDMQDPQSSDFILKLSDFYRFTLESRKMDLIPLKEELQILDSYVYLLKARFEDGFEVIKEIDA
QQYDCAIPPFSLQLLIENCIKHNIVSLDKPLKIKLYTENDFLVIENPIQLKRGTLSTGVGLNNINQRFLHLVNKEIEIDK
TETHFKVKIPLIYDYHNN

Sequences:

>Translated_338_residues
MEKAKRFQVSLKVIWGSSIALAVMASIPKLFDADSTPGDLIINSSITLLFSLFIWYYNIYSLPKFSSQRTNKSLFNWKLL
LSVVLGILLMVILVIAHQELFQVSKMDAPIMFELRGVLINLIVYMFLHLLFQNYQTQQMGVELERTKAVHLGAQYELLKQ
QVNPHFLFNSLNTLKSMVDMQDPQSSDFILKLSDFYRFTLESRKMDLIPLKEELQILDSYVYLLKARFEDGFEVIKEIDA
QQYDCAIPPFSLQLLIENCIKHNIVSLDKPLKIKLYTENDFLVIENPIQLKRGTLSTGVGLNNINQRFLHLVNKEIEIDK
TETHFKVKIPLIYDYHNN
>Mature_338_residues
MEKAKRFQVSLKVIWGSSIALAVMASIPKLFDADSTPGDLIINSSITLLFSLFIWYYNIYSLPKFSSQRTNKSLFNWKLL
LSVVLGILLMVILVIAHQELFQVSKMDAPIMFELRGVLINLIVYMFLHLLFQNYQTQQMGVELERTKAVHLGAQYELLKQ
QVNPHFLFNSLNTLKSMVDMQDPQSSDFILKLSDFYRFTLESRKMDLIPLKEELQILDSYVYLLKARFEDGFEVIKEIDA
QQYDCAIPPFSLQLLIENCIKHNIVSLDKPLKIKLYTENDFLVIENPIQLKRGTLSTGVGLNNINQRFLHLVNKEIEIDK
TETHFKVKIPLIYDYHNN

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=203, Percent_Identity=30.0492610837438, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788723, Length=164, Percent_Identity=31.7073170731707, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39264; Mature: 39264

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAKRFQVSLKVIWGSSIALAVMASIPKLFDADSTPGDLIINSSITLLFSLFIWYYNIY
CCCCCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
SLPKFSSQRTNKSLFNWKLLLSVVLGILLMVILVIAHQELFQVSKMDAPIMFELRGVLIN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LIVYMFLHLLFQNYQTQQMGVELERTKAVHLGAQYELLKQQVNPHFLFNSLNTLKSMVDM
HHHHHHHHHHHHCCCHHHHCCCHHHHHEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHC
QDPQSSDFILKLSDFYRFTLESRKMDLIPLKEELQILDSYVYLLKARFEDGFEVIKEIDA
CCCCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QQYDCAIPPFSLQLLIENCIKHNIVSLDKPLKIKLYTENDFLVIENPIQLKRGTLSTGVG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECCCHHHCCCCCCCCCC
LNNINQRFLHLVNKEIEIDKTETHFKVKIPLIYDYHNN
CCHHHHHHHHHHCCCCEECCCCCEEEEEEEEEEECCCC
>Mature Secondary Structure
MEKAKRFQVSLKVIWGSSIALAVMASIPKLFDADSTPGDLIINSSITLLFSLFIWYYNIY
CCCCCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHH
SLPKFSSQRTNKSLFNWKLLLSVVLGILLMVILVIAHQELFQVSKMDAPIMFELRGVLIN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LIVYMFLHLLFQNYQTQQMGVELERTKAVHLGAQYELLKQQVNPHFLFNSLNTLKSMVDM
HHHHHHHHHHHHCCCHHHHCCCHHHHHEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHC
QDPQSSDFILKLSDFYRFTLESRKMDLIPLKEELQILDSYVYLLKARFEDGFEVIKEIDA
CCCCCCCEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QQYDCAIPPFSLQLLIENCIKHNIVSLDKPLKIKLYTENDFLVIENPIQLKRGTLSTGVG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEECCCHHHCCCCCCCCCC
LNNINQRFLHLVNKEIEIDKTETHFKVKIPLIYDYHNN
CCHHHHHHHHHHCCCCEECCCCCEEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA