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The map label for this gene is csd [H]

Identifier: 146301728

GI number: 146301728

Start: 4773309

End: 4774793

Strand: Reverse

Name: csd [H]

Synonym: Fjoh_3990

Alternate gene names: 146301728

Gene position: 4774793-4773309 (Counterclockwise)

Preceding gene: 146301729

Following gene: 146301726

Centisome position: 78.32

GC content: 36.9

Gene sequence:

>1485_bases
ATGATAAAGGAAATGAATGCTATTGAGCCAACAACAAAACCAACAGAGTCTGAATGTTACTTTTCTAAGTTTAGAGAAAA
TACAGTAGGAATTGATCATACTTTCGAATCGGTTTACGGAGAGCAAAATCTGATATATGCTGACTGGGTTGCCAGTGGAA
GGCTGTATATCCCGATCGAAGATATAATGCTCAATAAAATCGGCCCAATGATTGCCAATACGCATTCACTTTCAAGTCAA
ACAGGAAAAACGTCCACGTATGCGTATCAGTATGCAAGAGATATTATTAAAAAATCGGTTAACGCTAATGAATCAGATGT
TTTGATAACAACCGGAAGCGGTATGACAGCAGCTTTATCGAAACTGCAGCGTATTATGGCTCTGAGAACAAAATCAGATC
AGGATAGACCTGTCGTTTTTATCACACACATGGAACATCACTCCAATCAGGTTTCGTGGTATGAAACCAATGCCGAAGTT
GTGATTTTACCGCCTGATGAAAATAATTTAGTTGATCCGAAGGTACTTTCTCAGGAAATCAAAAAATATGCAGACAGAAG
CTTAAAAATAGGTTCATTTACGGCCTGTTCGAATGTTACGGGAATTATTACGCCTTATCATGAATTAGCCAAAATTATGC
ACCAAAACGGGGGACTTTGTTTTGTAGATTTTGCAGCTTCGGCACCGTATGTCAAAATCGATATGCATCCAAAAGATCCA
GAACAGCAATTGGATGCAATTTTCTTTTCGCCTCATAAATTTTTGGGCGGACCCGGAACCTGCGGTATTTTAGTTTTTAA
TGAAAAATTATACCAATCTGATTTTCCAGATAATCCGGGCGGGGGAAATGTAAAATGGACCAATCCGTTAGGAAAATATT
GTTACAGCGATGTAATAGAAGTGAGGGAAGATGGCGGGACTCCGGGGTTTCTGCAGGTTATTAGAACTGCTTTGTCTTTA
GAATTAAAAGAACAAATGGGAGTTGAGAAAATCAAAAAGAGAGAAAAAGAACTGCTTGACCTTTGTTTTTCGAGACTTCA
AAAAATACAAGGATTATCCATTTTAGGCGATTTAACCACAGAAAGAATTGGCTGTGTTTCTTTTGTAATCGAAGATATTC
ATTACAATTTAATTGTTAGGCTTTTAAATGACCGTTTTGGAATTCAGGTTCGCGGCGGCTGGTCTTGTGCAAGTACTTAT
GCGCATTATTTGTTTAACATCAACGAAAAAAGATCGGCTGAAATTACAAATGAATTGTTACAGCGAAATCAATCCAATAA
ACCGGGCTGGGTGCGTTTATCACTGCATCCGATTATGACAAATGAAGCGCTTTTTTATATCTGCGATGCAATCGAGAAAA
TAGCTTCGAATTATAAAAAATGGAAGAAGGATTATGAATATAATCCGGTTTCAAATGAATTTGAAAACCCTGAAATAAAA
GAAAATATAGCAGAAGAAGTAAATGAATGGTTTAAGTTAGTTTAA

Upstream 100 bases:

>100_bases
AAAGTCGTCAATCTTTGTCGAGTTACATGTGTGATTTCTCCTCCGTCGAAATGACAAAAAGAAGAATAAAACACATGCAA
ATACAATTTAGTTAATTAAA

Downstream 100 bases:

>100_bases
GTATAGTTAATTAAGTTTTAAACCCGACAGGTTTTTAAAACCTGTCGGGTTTATAATGAGTAATATTCCGTAGGAATATC
TCGCTGGTAGAAAAATGGTA

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MIKEMNAIEPTTKPTESECYFSKFRENTVGIDHTFESVYGEQNLIYADWVASGRLYIPIEDIMLNKIGPMIANTHSLSSQ
TGKTSTYAYQYARDIIKKSVNANESDVLITTGSGMTAALSKLQRIMALRTKSDQDRPVVFITHMEHHSNQVSWYETNAEV
VILPPDENNLVDPKVLSQEIKKYADRSLKIGSFTACSNVTGIITPYHELAKIMHQNGGLCFVDFAASAPYVKIDMHPKDP
EQQLDAIFFSPHKFLGGPGTCGILVFNEKLYQSDFPDNPGGGNVKWTNPLGKYCYSDVIEVREDGGTPGFLQVIRTALSL
ELKEQMGVEKIKKREKELLDLCFSRLQKIQGLSILGDLTTERIGCVSFVIEDIHYNLIVRLLNDRFGIQVRGGWSCASTY
AHYLFNINEKRSAEITNELLQRNQSNKPGWVRLSLHPIMTNEALFYICDAIEKIASNYKKWKKDYEYNPVSNEFENPEIK
ENIAEEVNEWFKLV

Sequences:

>Translated_494_residues
MIKEMNAIEPTTKPTESECYFSKFRENTVGIDHTFESVYGEQNLIYADWVASGRLYIPIEDIMLNKIGPMIANTHSLSSQ
TGKTSTYAYQYARDIIKKSVNANESDVLITTGSGMTAALSKLQRIMALRTKSDQDRPVVFITHMEHHSNQVSWYETNAEV
VILPPDENNLVDPKVLSQEIKKYADRSLKIGSFTACSNVTGIITPYHELAKIMHQNGGLCFVDFAASAPYVKIDMHPKDP
EQQLDAIFFSPHKFLGGPGTCGILVFNEKLYQSDFPDNPGGGNVKWTNPLGKYCYSDVIEVREDGGTPGFLQVIRTALSL
ELKEQMGVEKIKKREKELLDLCFSRLQKIQGLSILGDLTTERIGCVSFVIEDIHYNLIVRLLNDRFGIQVRGGWSCASTY
AHYLFNINEKRSAEITNELLQRNQSNKPGWVRLSLHPIMTNEALFYICDAIEKIASNYKKWKKDYEYNPVSNEFENPEIK
ENIAEEVNEWFKLV
>Mature_494_residues
MIKEMNAIEPTTKPTESECYFSKFRENTVGIDHTFESVYGEQNLIYADWVASGRLYIPIEDIMLNKIGPMIANTHSLSSQ
TGKTSTYAYQYARDIIKKSVNANESDVLITTGSGMTAALSKLQRIMALRTKSDQDRPVVFITHMEHHSNQVSWYETNAEV
VILPPDENNLVDPKVLSQEIKKYADRSLKIGSFTACSNVTGIITPYHELAKIMHQNGGLCFVDFAASAPYVKIDMHPKDP
EQQLDAIFFSPHKFLGGPGTCGILVFNEKLYQSDFPDNPGGGNVKWTNPLGKYCYSDVIEVREDGGTPGFLQVIRTALSL
ELKEQMGVEKIKKREKELLDLCFSRLQKIQGLSILGDLTTERIGCVSFVIEDIHYNLIVRLLNDRFGIQVRGGWSCASTY
AHYLFNINEKRSAEITNELLQRNQSNKPGWVRLSLHPIMTNEALFYICDAIEKIASNYKKWKKDYEYNPVSNEFENPEIK
ENIAEEVNEWFKLV

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=265, Percent_Identity=30.188679245283, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789175, Length=331, Percent_Identity=26.8882175226586, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193211090, Length=482, Percent_Identity=29.8755186721992, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 56075; Mature: 56075

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEMNAIEPTTKPTESECYFSKFRENTVGIDHTFESVYGEQNLIYADWVASGRLYIPIE
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCEEEEEHH
DIMLNKIGPMIANTHSLSSQTGKTSTYAYQYARDIIKKSVNANESDVLITTGSGMTAALS
HHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
KLQRIMALRTKSDQDRPVVFITHMEHHSNQVSWYETNAEVVILPPDENNLVDPKVLSQEI
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHH
KKYADRSLKIGSFTACSNVTGIITPYHELAKIMHQNGGLCFVDFAASAPYVKIDMHPKDP
HHHHCCCEECCCEEHHCCCCEEECCHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCH
EQQLDAIFFSPHKFLGGPGTCGILVFNEKLYQSDFPDNPGGGNVKWTNPLGKYCYSDVIE
HHHHHHHEECCHHHCCCCCCEEEEEEECHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHH
VREDGGTPGFLQVIRTALSLELKEQMGVEKIKKREKELLDLCFSRLQKIQGLSILGDLTT
HHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ERIGCVSFVIEDIHYNLIVRLLNDRFGIQVRGGWSCASTYAHYLFNINEKRSAEITNELL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHH
QRNQSNKPGWVRLSLHPIMTNEALFYICDAIEKIASNYKKWKKDYEYNPVSNEFENPEIK
HCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ENIAEEVNEWFKLV
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIKEMNAIEPTTKPTESECYFSKFRENTVGIDHTFESVYGEQNLIYADWVASGRLYIPIE
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCEEEEEHH
DIMLNKIGPMIANTHSLSSQTGKTSTYAYQYARDIIKKSVNANESDVLITTGSGMTAALS
HHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
KLQRIMALRTKSDQDRPVVFITHMEHHSNQVSWYETNAEVVILPPDENNLVDPKVLSQEI
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHH
KKYADRSLKIGSFTACSNVTGIITPYHELAKIMHQNGGLCFVDFAASAPYVKIDMHPKDP
HHHHCCCEECCCEEHHCCCCEEECCHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCH
EQQLDAIFFSPHKFLGGPGTCGILVFNEKLYQSDFPDNPGGGNVKWTNPLGKYCYSDVIE
HHHHHHHEECCHHHCCCCCCEEEEEEECHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHH
VREDGGTPGFLQVIRTALSLELKEQMGVEKIKKREKELLDLCFSRLQKIQGLSILGDLTT
HHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ERIGCVSFVIEDIHYNLIVRLLNDRFGIQVRGGWSCASTYAHYLFNINEKRSAEITNELL
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHH
QRNQSNKPGWVRLSLHPIMTNEALFYICDAIEKIASNYKKWKKDYEYNPVSNEFENPEIK
HCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ENIAEEVNEWFKLV
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]