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The map label for this gene is hypE [H]

Identifier: 146301641

GI number: 146301641

Start: 4649230

End: 4650240

Strand: Reverse

Name: hypE [H]

Synonym: Fjoh_3902

Alternate gene names: 146301641

Gene position: 4650240-4649230 (Counterclockwise)

Preceding gene: 146301642

Following gene: 146301640

Centisome position: 76.27

GC content: 35.41

Gene sequence:

>1011_bases
ATGGAAAAAGAACAGGAAGTAATTCACCTGCATCACGGAAGCGGCGGTGAACACATGACCAAATTACTCAATGAAGTAAT
TTTTAAGATTTTAAAAAATGATATTTTAGAAGTCCGTCACGATGGCGCCTTTTTAAACGTACAAGGAAATCTGGCTTTTT
CTACAGATAGTTATGTTATTTCTCCCGTATTTTTTAAAGGCGGCAACATTGGTGAACTTGCCGTAAACGGAACTGTAAAT
GATCTTTCAATGTGTGGTGCAGTTCCAAAATACCTTTCGCTGGCCTTAATTATTGAAGAAGGTTTTAGTTTAGAAGAATT
TACAGAAATTATAAAATCAATTAAACAAGCGGCAGATAATGCAGGTATTCAAATCGTTACCGGAGATACTAAGGTTGTAG
AAAGAGGAAAAGGAGATAAAATTTACATTAATACTTCGGGAATTGGTGTTGTTCACAAAAAAGCCAATATCAAAATTAGA
AATATCCAGCAAAATGATGTTGTTATCATAAACGGGCCGATAGCATCGCACGGAATGGCCATTATGTCGGAACGTGAAGG
ACTTGAATTTGAAAGTGATATTTTGAGCGATACCACAAATTTAAATCACATCGTTTTTGATTTAATAGAACAGTTTGGTG
ATAAAATTCATTTTTTGAGAGACGCAACCCGCGGCGGACTGGCTTCTGTACTGCATGAAATAACTACCGAAATTAATTTC
GGCATTTCTCTTTTTGAAGAAAACATAAAAGTAGAAAGTCAGGTAAAAAGTGCCTGCGAACTGCTTGGTTTAGATCCGCT
TTATGTAGCTAACGAAGGAGTTTTTGTCTGTATTGCAGCACCAGAAATTAAAAATGAAGTATTGAAGATTTTACAAAAAA
CAAATCCAAAGGCATCAGAGATTGGTTTTATAAGCGGAGAACATCCATCAAAAATAATTATCGAAAGTGCTTTTGGAGGA
AAAAGAGTTGTAAATCCTTTAGTTGGAGAACAGCTGCCAAGAATTTGCTAA

Upstream 100 bases:

>100_bases
GTTCATGTTGGCGCTGCAATTGGAATTATTGATGAAGATGAAGCCAAAAGGACAATGGAGATTTTAAAAGAAATGGGCGA
AGAGATTTAATGCATAAAAA

Downstream 100 bases:

>100_bases
GCAGTATTTTTGAGTTTATTTTTATCTGAAATATTAAGTTGTAATTTGACTTTATATTTTATTATTTCGCATTTTTATTA
CACTTCTATGAGATTTTTAT

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MEKEQEVIHLHHGSGGEHMTKLLNEVIFKILKNDILEVRHDGAFLNVQGNLAFSTDSYVISPVFFKGGNIGELAVNGTVN
DLSMCGAVPKYLSLALIIEEGFSLEEFTEIIKSIKQAADNAGIQIVTGDTKVVERGKGDKIYINTSGIGVVHKKANIKIR
NIQQNDVVIINGPIASHGMAIMSEREGLEFESDILSDTTNLNHIVFDLIEQFGDKIHFLRDATRGGLASVLHEITTEINF
GISLFEENIKVESQVKSACELLGLDPLYVANEGVFVCIAAPEIKNEVLKILQKTNPKASEIGFISGEHPSKIIIESAFGG
KRVVNPLVGEQLPRIC

Sequences:

>Translated_336_residues
MEKEQEVIHLHHGSGGEHMTKLLNEVIFKILKNDILEVRHDGAFLNVQGNLAFSTDSYVISPVFFKGGNIGELAVNGTVN
DLSMCGAVPKYLSLALIIEEGFSLEEFTEIIKSIKQAADNAGIQIVTGDTKVVERGKGDKIYINTSGIGVVHKKANIKIR
NIQQNDVVIINGPIASHGMAIMSEREGLEFESDILSDTTNLNHIVFDLIEQFGDKIHFLRDATRGGLASVLHEITTEINF
GISLFEENIKVESQVKSACELLGLDPLYVANEGVFVCIAAPEIKNEVLKILQKTNPKASEIGFISGEHPSKIIIESAFGG
KRVVNPLVGEQLPRIC
>Mature_336_residues
MEKEQEVIHLHHGSGGEHMTKLLNEVIFKILKNDILEVRHDGAFLNVQGNLAFSTDSYVISPVFFKGGNIGELAVNGTVN
DLSMCGAVPKYLSLALIIEEGFSLEEFTEIIKSIKQAADNAGIQIVTGDTKVVERGKGDKIYINTSGIGVVHKKANIKIR
NIQQNDVVIINGPIASHGMAIMSEREGLEFESDILSDTTNLNHIVFDLIEQFGDKIHFLRDATRGGLASVLHEITTEINF
GISLFEENIKVESQVKSACELLGLDPLYVANEGVFVCIAAPEIKNEVLKILQKTNPKASEIGFISGEHPSKIIIESAFGG
KRVVNPLVGEQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=40.0593471810089, Blast_Score=238, Evalue=5e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36713; Mature: 36713

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKEQEVIHLHHGSGGEHMTKLLNEVIFKILKNDILEVRHDGAFLNVQGNLAFSTDSYVI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCEEECCCCEEE
SPVFFKGGNIGELAVNGTVNDLSMCGAVPKYLSLALIIEEGFSLEEFTEIIKSIKQAADN
EEEEECCCCEEEEEECCCCHHHHHHCCHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCC
AGIQIVTGDTKVVERGKGDKIYINTSGIGVVHKKANIKIRNIQQNDVVIINGPIASHGMA
CCEEEEECCHHHHHCCCCCEEEEEECCCEEEEEECCEEEEEECCCCEEEEECCCCCCCHH
IMSEREGLEFESDILSDTTNLNHIVFDLIEQFGDKIHFLRDATRGGLASVLHEITTEINF
EEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHCHHEEHHHHCCCCHHHHHHHHHHHHHHC
GISLFEENIKVESQVKSACELLGLDPLYVANEGVFVCIAAPEIKNEVLKILQKTNPKASE
CHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCCHHH
IGFISGEHPSKIIIESAFGGKRVVNPLVGEQLPRIC
CCEECCCCCCEEEEEECCCCCHHHCHHHHHHCCCCC
>Mature Secondary Structure
MEKEQEVIHLHHGSGGEHMTKLLNEVIFKILKNDILEVRHDGAFLNVQGNLAFSTDSYVI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCEEECCCCEEE
SPVFFKGGNIGELAVNGTVNDLSMCGAVPKYLSLALIIEEGFSLEEFTEIIKSIKQAADN
EEEEECCCCEEEEEECCCCHHHHHHCCHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCC
AGIQIVTGDTKVVERGKGDKIYINTSGIGVVHKKANIKIRNIQQNDVVIINGPIASHGMA
CCEEEEECCHHHHHCCCCCEEEEEECCCEEEEEECCEEEEEECCCCEEEEECCCCCCCHH
IMSEREGLEFESDILSDTTNLNHIVFDLIEQFGDKIHFLRDATRGGLASVLHEITTEINF
EEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHCHHEEHHHHCCCCHHHHHHHHHHHHHHC
GISLFEENIKVESQVKSACELLGLDPLYVANEGVFVCIAAPEIKNEVLKILQKTNPKASE
CHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCCHHH
IGFISGEHPSKIIIESAFGGKRVVNPLVGEQLPRIC
CCEECCCCCCEEEEEECCCCCHHHCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8326860 [H]