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The map label for this gene is exsA [H]

Identifier: 146301634

GI number: 146301634

Start: 4640831

End: 4641679

Strand: Reverse

Name: exsA [H]

Synonym: Fjoh_3895

Alternate gene names: 146301634

Gene position: 4641679-4640831 (Counterclockwise)

Preceding gene: 146301635

Following gene: 146301633

Centisome position: 76.13

GC content: 28.39

Gene sequence:

>849_bases
ATGATAAACGACTATAAAAAGCATGATTTATATGGCATGACATTAATTCAAAAAATTGAATTAACACCGCCGTTTAAATT
TGATTTTCCAATTACTGAACAGGCTTGCTTTTTATATGTAAAAGAAGGAGAGATTGATTATTATATTGATAATGAAAATG
TGAATGTTTCTACAAATTATTCCTTATTAGTGAATTGTATGGATTCTGGTAAGCAATTGCACAATTCAAATTCCAATAAT
AATTGTGAAATAGTAATTGTAACGTTCTATCCTAAAATATTAAAGAAAATATACGAAAAGGAACTTCCATTATTGTTTCA
AAGACCTGAAAGTTTAATATCGAATAAATCAAGTGAAAGAATAAATAACGATTTTCTAATTCAAAAGTATATTGAAGGAT
TATTGTTTTATTTTGAAAATCCGTCTTTAATCAATGAAGATATCTTAGTTCTAAAATTAAAAGAAATTATACTTTTATTA
TCTCAGACACAAAATTCAGAATCAATACAGCTGATATTATCCCAGCTTTTTTCTCCAACGACTTATAGTTTCAGACAAAT
AATCGAAGCAAATTTGTTTTCGCAGCTCACTATTGAAGAATTAGCACAACAGAATAATTTAAGTGTTTCATCGTTTAAAC
GCGAATTTTCAAAAATATATCACGATACTCCCGCTAATTACATTAAAACTAAAAAACTTATGAAAGCGGCAGAGATGCTT
CAGGTTTCTGACCAGCGTATTACTGAAATAGCTTTTGACTGCGGTTTTAATGATCTGGCAAATTTTACCAAAAGTTTTAC
CAGCAAATATGGTATCAGTCCCACAAATTACAGGCAGAAACTTAAATAG

Upstream 100 bases:

>100_bases
TTGTGATGTATGACAGGAATTTATCCAAACCAAGATCTTAAACGAAAAATTTAATAATTTGTATTTCATAATAGTTAAAG
AAAATTAGCAGATTTTTTTT

Downstream 100 bases:

>100_bases
TAAATACTAATTAGAATTTTATTTAAAGTTTTTCATGAACGAAATCACCAAATAATTGAACTATTTGACAAAACCATTTC
TGTTAATCTATCGGAAGTTT

Product: helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MINDYKKHDLYGMTLIQKIELTPPFKFDFPITEQACFLYVKEGEIDYYIDNENVNVSTNYSLLVNCMDSGKQLHNSNSNN
NCEIVIVTFYPKILKKIYEKELPLLFQRPESLISNKSSERINNDFLIQKYIEGLLFYFENPSLINEDILVLKLKEIILLL
SQTQNSESIQLILSQLFSPTTYSFRQIIEANLFSQLTIEELAQQNNLSVSSFKREFSKIYHDTPANYIKTKKLMKAAEML
QVSDQRITEIAFDCGFNDLANFTKSFTSKYGISPTNYRQKLK

Sequences:

>Translated_282_residues
MINDYKKHDLYGMTLIQKIELTPPFKFDFPITEQACFLYVKEGEIDYYIDNENVNVSTNYSLLVNCMDSGKQLHNSNSNN
NCEIVIVTFYPKILKKIYEKELPLLFQRPESLISNKSSERINNDFLIQKYIEGLLFYFENPSLINEDILVLKLKEIILLL
SQTQNSESIQLILSQLFSPTTYSFRQIIEANLFSQLTIEELAQQNNLSVSSFKREFSKIYHDTPANYIKTKKLMKAAEML
QVSDQRITEIAFDCGFNDLANFTKSFTSKYGISPTNYRQKLK
>Mature_282_residues
MINDYKKHDLYGMTLIQKIELTPPFKFDFPITEQACFLYVKEGEIDYYIDNENVNVSTNYSLLVNCMDSGKQLHNSNSNN
NCEIVIVTFYPKILKKIYEKELPLLFQRPESLISNKSSERINNDFLIQKYIEGLLFYFENPSLINEDILVLKLKEIILLL
SQTQNSESIQLILSQLFSPTTYSFRQIIEANLFSQLTIEELAQQNNLSVSSFKREFSKIYHDTPANYIKTKKLMKAAEML
QVSDQRITEIAFDCGFNDLANFTKSFTSKYGISPTNYRQKLK

Specific function: Appears to be required for induction of exoenzyme S synthesis above a low basal level [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 32860; Mature: 32860

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDYKKHDLYGMTLIQKIELTPPFKFDFPITEQACFLYVKEGEIDYYIDNENVNVSTNY
CCCCCCCCCHHHHHHHHHEECCCCCEECCCCCCCEEEEEEEECCEEEEECCCCEEEECCH
SLLVNCMDSGKQLHNSNSNNNCEIVIVTFYPKILKKIYEKELPLLFQRPESLISNKSSER
HEEEEEHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHCCCHHHHCCCCHHH
INNDFLIQKYIEGLLFYFENPSLINEDILVLKLKEIILLLSQTQNSESIQLILSQLFSPT
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
TYSFRQIIEANLFSQLTIEELAQQNNLSVSSFKREFSKIYHDTPANYIKTKKLMKAAEML
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QVSDQRITEIAFDCGFNDLANFTKSFTSKYGISPTNYRQKLK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MINDYKKHDLYGMTLIQKIELTPPFKFDFPITEQACFLYVKEGEIDYYIDNENVNVSTNY
CCCCCCCCCHHHHHHHHHEECCCCCEECCCCCCCEEEEEEEECCEEEEECCCCEEEECCH
SLLVNCMDSGKQLHNSNSNNNCEIVIVTFYPKILKKIYEKELPLLFQRPESLISNKSSER
HEEEEEHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHCCCHHHCCCHHHHCCCCHHH
INNDFLIQKYIEGLLFYFENPSLINEDILVLKLKEIILLLSQTQNSESIQLILSQLFSPT
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
TYSFRQIIEANLFSQLTIEELAQQNNLSVSSFKREFSKIYHDTPANYIKTKKLMKAAEML
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QVSDQRITEIAFDCGFNDLANFTKSFTSKYGISPTNYRQKLK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655713; 10984043 [H]