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The map label for this gene is kdsA [H]

Identifier: 146301255

GI number: 146301255

Start: 4187143

End: 4187994

Strand: Direct

Name: kdsA [H]

Synonym: Fjoh_3513

Alternate gene names: 146301255

Gene position: 4187143-4187994 (Clockwise)

Preceding gene: 146301254

Following gene: 146301256

Centisome position: 68.68

GC content: 35.8

Gene sequence:

>852_bases
ATGACTACCTTTGCATTGCAAAAAAATAATTTTATGAACTTACAACATATTCCACAAATCAAGCATACTGAAAGCGGAAA
TTTCTTTTTATTGGCGGGGCCATGCGCTATTGAAGGAGAAGAAATGGCTCTTAGAATTGCTGAAAAATTAGTTGGTATTA
CCGACAACTTACAAATCCCTTATGTGTTTAAAGGATCTTTTAAAAAAGCAAACCGTTCCAGAATTGATAGTTTTTCTGGA
ATTGGAGATGAAAAAGCTTTAAAAATATTAAGAAAAGTTTCAGAAACTTTTCACGTTCCAACTGTTACCGATATTCATAC
AAATGAAGATGCCGATATGGCTGCACAGTACGTTGATGTTTTACAAATTCCTGCGTTTTTAGTTCGTCAGACAGATTTGG
TTGTTGCTGCCGCTAATACAGGAAAAACAGTAAACCTTAAAAAAGGACAATTTATGAGTCCAGAAAGCATGAAACATGCT
GTACAAAAGGTTTTAGACTGTAATAACGAAAACGTTATGGTTACAGACAGAGGTACTATGTTTGGATACCAGGATATGAT
TGTTGATTTTAGAGGAATTCCTACTATGCAGCAATATGCATCTACGGTTTTAGATGTTACACACTCTTTACAGCAGCCAA
ACCAGACTGCTGGTGTTACAGGCGGAAGACCTGACATGATCGAAACAGTAGCAAAAGCGGGTATCGCTGTAGGTGTTGAC
GGTATTTTTATCGAAACACACTTTGACCCTGCAAATGCAAAAAGTGATGGTGCTAATATGCTTCATTTAGACTATTTTGA
AGGTTTAATGAACAAATTAGTGGCTATTAGAAAAACTGTAAATGCCTTTTAA

Upstream 100 bases:

>100_bases
TTCTTAAGAAATTTTAGAAATTCGTTACTGCTGCTAAGCCCCCTGTCAGCTATTCGTGTTCTTAAAATAATCTTAAATCT
TCATCTGCTATTCATAAATC

Downstream 100 bases:

>100_bases
TTTATAATACTTAAGTTCTTTGAAAACAAAAATTTTATTTTTCTTACTGGCTTGTGTTTCTTTAAACACATTTGCTCAGG
AAGAAATTCCAGTACAAAAA

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTTFALQKNNFMNLQHIPQIKHTESGNFFLLAGPCAIEGEEMALRIAEKLVGITDNLQIPYVFKGSFKKANRSRIDSFSG
IGDEKALKILRKVSETFHVPTVTDIHTNEDADMAAQYVDVLQIPAFLVRQTDLVVAAANTGKTVNLKKGQFMSPESMKHA
VQKVLDCNNENVMVTDRGTMFGYQDMIVDFRGIPTMQQYASTVLDVTHSLQQPNQTAGVTGGRPDMIETVAKAGIAVGVD
GIFIETHFDPANAKSDGANMLHLDYFEGLMNKLVAIRKTVNAF

Sequences:

>Translated_283_residues
MTTFALQKNNFMNLQHIPQIKHTESGNFFLLAGPCAIEGEEMALRIAEKLVGITDNLQIPYVFKGSFKKANRSRIDSFSG
IGDEKALKILRKVSETFHVPTVTDIHTNEDADMAAQYVDVLQIPAFLVRQTDLVVAAANTGKTVNLKKGQFMSPESMKHA
VQKVLDCNNENVMVTDRGTMFGYQDMIVDFRGIPTMQQYASTVLDVTHSLQQPNQTAGVTGGRPDMIETVAKAGIAVGVD
GIFIETHFDPANAKSDGANMLHLDYFEGLMNKLVAIRKTVNAF
>Mature_282_residues
TTFALQKNNFMNLQHIPQIKHTESGNFFLLAGPCAIEGEEMALRIAEKLVGITDNLQIPYVFKGSFKKANRSRIDSFSGI
GDEKALKILRKVSETFHVPTVTDIHTNEDADMAAQYVDVLQIPAFLVRQTDLVVAAANTGKTVNLKKGQFMSPESMKHAV
QKVLDCNNENVMVTDRGTMFGYQDMIVDFRGIPTMQQYASTVLDVTHSLQQPNQTAGVTGGRPDMIETVAKAGIAVGVDG
IFIETHFDPANAKSDGANMLHLDYFEGLMNKLVAIRKTVNAF

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=259, Percent_Identity=43.6293436293436, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 31172; Mature: 31041

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFALQKNNFMNLQHIPQIKHTESGNFFLLAGPCAIEGEEMALRIAEKLVGITDNLQIP
CCEEEECCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEE
YVFKGSFKKANRSRIDSFSGIGDEKALKILRKVSETFHVPTVTDIHTNEDADMAAQYVDV
EEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
LQIPAFLVRQTDLVVAAANTGKTVNLKKGQFMSPESMKHAVQKVLDCNNENVMVTDRGTM
HHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
FGYQDMIVDFRGIPTMQQYASTVLDVTHSLQQPNQTAGVTGGRPDMIETVAKAGIAVGVD
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECC
GIFIETHFDPANAKSDGANMLHLDYFEGLMNKLVAIRKTVNAF
EEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTFALQKNNFMNLQHIPQIKHTESGNFFLLAGPCAIEGEEMALRIAEKLVGITDNLQIP
CEEEECCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEE
YVFKGSFKKANRSRIDSFSGIGDEKALKILRKVSETFHVPTVTDIHTNEDADMAAQYVDV
EEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHH
LQIPAFLVRQTDLVVAAANTGKTVNLKKGQFMSPESMKHAVQKVLDCNNENVMVTDRGTM
HHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
FGYQDMIVDFRGIPTMQQYASTVLDVTHSLQQPNQTAGVTGGRPDMIETVAKAGIAVGVD
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEECC
GIFIETHFDPANAKSDGANMLHLDYFEGLMNKLVAIRKTVNAF
EEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA