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The map label for this gene is dapB [H]

Identifier: 146301071

GI number: 146301071

Start: 3976533

End: 3977282

Strand: Reverse

Name: dapB [H]

Synonym: Fjoh_3327

Alternate gene names: 146301071

Gene position: 3977282-3976533 (Counterclockwise)

Preceding gene: 146301086

Following gene: 146301066

Centisome position: 65.23

GC content: 33.73

Gene sequence:

>750_bases
ATGAAAATAGGATTAATCGGATTTGGAAAGACTGGAAAATCAGTAGCGTCAATATTACTGGAAAACAAAAAATTCTCTCT
GGAGTGGGTTTTAAGACAAAGTAAAGTTTTAGAACACAGATCAGTTCCGGAATTTTTTGGAGTCGAGTCAGAAGAACCCG
GATTAATTTATTCAAGTGCCACTACAAGTATAGAGGAATTACTGGAAAAACATCCGGTTGATGTTATTATTGATTTTTCA
TCAAATGAAGGAATTTACACTTATGGAGAATCGGCGGCATTAAACAACGTTAAAATTATTTCTGCAATTTCACATTATGA
AGAAAATGAATTAAAACTACTCAAAAAATTATCGAATAAAACAACCGTTTTCTGGTCGCCAAATATCACATTAGGAGTCA
ATTATTTATTGTTTGCGGCCAAGTTTTTAAAGAAAATTGCCCCTTGGGTTGATATTGAAGTAAATGAAGAACATTTTAAG
AAAAAACAAGGCACATCGGGGACCGCTTTAAAAATAGCCGAAGCGCTTGATGTTGAAAAAGAAAACATCAATTCGGTAAG
AGCGGGAGGAATAGTTGGAAAACATGAAGTTATCTTCGGATTTCCGTATCAAACGGTTCGTTTAATTCATGAATCGATTT
CAAGAGAAGCCTTTGGAAACGGAGTCGTTTTTGTAGCTGAGAATTTAAAAGACAAGAAAAAAGGACTTTACAATTTTGAA
GATATTTTGACGCCTTATTTTGCGATTTAA

Upstream 100 bases:

>100_bases
TATTTTAGGGTTTTTTTTTCGAGCAATTTCCTGATTGTTCTGCCTTCTAAAAGTATCAATTTCTGCTAACGAGTTTCATA
CTCAATTTAAAAAATATTAT

Downstream 100 bases:

>100_bases
GATTTTTTAATGAATTGTTTTTGTCCTTCTAAACGAAATCAAAATATATTTTTATCTCGCAAAGACGCAGATTCGCAAAG
ATCTTCTTTTTTAAGTTTTA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKIGLIGFGKTGKSVASILLENKKFSLEWVLRQSKVLEHRSVPEFFGVESEEPGLIYSSATTSIEELLEKHPVDVIIDFS
SNEGIYTYGESAALNNVKIISAISHYEENELKLLKKLSNKTTVFWSPNITLGVNYLLFAAKFLKKIAPWVDIEVNEEHFK
KKQGTSGTALKIAEALDVEKENINSVRAGGIVGKHEVIFGFPYQTVRLIHESISREAFGNGVVFVAENLKDKKKGLYNFE
DILTPYFAI

Sequences:

>Translated_249_residues
MKIGLIGFGKTGKSVASILLENKKFSLEWVLRQSKVLEHRSVPEFFGVESEEPGLIYSSATTSIEELLEKHPVDVIIDFS
SNEGIYTYGESAALNNVKIISAISHYEENELKLLKKLSNKTTVFWSPNITLGVNYLLFAAKFLKKIAPWVDIEVNEEHFK
KKQGTSGTALKIAEALDVEKENINSVRAGGIVGKHEVIFGFPYQTVRLIHESISREAFGNGVVFVAENLKDKKKGLYNFE
DILTPYFAI
>Mature_249_residues
MKIGLIGFGKTGKSVASILLENKKFSLEWVLRQSKVLEHRSVPEFFGVESEEPGLIYSSATTSIEELLEKHPVDVIIDFS
SNEGIYTYGESAALNNVKIISAISHYEENELKLLKKLSNKTTVFWSPNITLGVNYLLFAAKFLKKIAPWVDIEVNEEHFK
KKQGTSGTALKIAEALDVEKENINSVRAGGIVGKHEVIFGFPYQTVRLIHESISREAFGNGVVFVAENLKDKKKGLYNFE
DILTPYFAI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 27873; Mature: 27873

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGLIGFGKTGKSVASILLENKKFSLEWVLRQSKVLEHRSVPEFFGVESEEPGLIYSSA
CEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEECH
TTSIEELLEKHPVDVIIDFSSNEGIYTYGESAALNNVKIISAISHYEENELKLLKKLSNK
HHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCEEHHHHHCCHHHHHHHHHHCCC
TTVFWSPNITLGVNYLLFAAKFLKKIAPWVDIEVNEEHFKKKQGTSGTALKIAEALDVEK
EEEEECCCCEEHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCHHHHHHHHCCCH
ENINSVRAGGIVGKHEVIFGFPYQTVRLIHESISREAFGNGVVFVAENLKDKKKGLYNFE
HHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHH
DILTPYFAI
HHHHHHHCC
>Mature Secondary Structure
MKIGLIGFGKTGKSVASILLENKKFSLEWVLRQSKVLEHRSVPEFFGVESEEPGLIYSSA
CEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEECH
TTSIEELLEKHPVDVIIDFSSNEGIYTYGESAALNNVKIISAISHYEENELKLLKKLSNK
HHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCEEHHHHHCCHHHHHHHHHHCCC
TTVFWSPNITLGVNYLLFAAKFLKKIAPWVDIEVNEEHFKKKQGTSGTALKIAEALDVEK
EEEEECCCCEEHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHCCCCCCHHHHHHHHCCCH
ENINSVRAGGIVGKHEVIFGFPYQTVRLIHESISREAFGNGVVFVAENLKDKKKGLYNFE
HHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCHH
DILTPYFAI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]