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The map label for this gene is pcbC [H]

Identifier: 146300589

GI number: 146300589

Start: 3370440

End: 3371390

Strand: Reverse

Name: pcbC [H]

Synonym: Fjoh_2839

Alternate gene names: 146300589

Gene position: 3371390-3370440 (Counterclockwise)

Preceding gene: 146300591

Following gene: 146300588

Centisome position: 55.3

GC content: 35.44

Gene sequence:

>951_bases
ATGCAAAACATTCCTAGTGTAGACTTACGTGATTTCCTTTCGGACGACCCGAAACGTAAACAAAAATTTGTAAATGAAAT
CGGCAGTGCATTTGAAAACATTGGCTTCGTTGCCTTAAAAGGTCATTTCTTAGATGACAAATTGGTAGACGAACTTTATG
GTGAAATTAGAAAATTTTTCGCCTTGCCAGTAGAAACTAAGCATAATTATGAAATTCCCGGAATTGGCGGCCAGAGAGGT
TATGTTTCTTTTGGAAAAGAACATGCTAAAGGACGCAAAGAAGGAGATTTGAAAGAATTCTGGCATTTTGGCCAGTATGT
TGACAAAGATTCAAAATGGGCTTCAGAATACCCTGATAACGTTGAAGTAAAAGAACTTCCTCGTTTTAATGAAGTAGGAA
AAGAAGCTTATCAAATGCTTGAAAAAACAGGAATTTATGTTTTAAGAGCTTTGGCTTTACATCTTGGTTTAGATGAGTTT
TATTTTGATGAATATGCAAAAGAAGGAAACTCTATTTTAAGACCAATTCATTATCCGCCAATTACTTCTGAGCCGGAAAA
TGCGATTCGTGCAGCAGCTCACGGCGACATTAATTTAATTACCTTATTAATGGGAGCTCAGGGTAAAGGTCTTCAGGTTC
AAAACCACAACGGAGATTGGATTGATGCTATTGCAGCAGATGACGAATTAGTAATTAATGTTGGAGATATGTTATCAAGA
CATACAAACAACAAATTAAAATCGACTATTCATCAGGTTGTAAATCCGCCAAGAGAATTATGGGGAACTTCTCGTTATTC
TGTTCCTTTCTTTATGCATCCTGTAAGCGATATGCGTTTAGATTGTCTTGAAAATTGTATCGATGAAGAAAATCCTAAAA
AATATGAGGATATTTCTGCGGGAGAGTTTTTACACGAACGTTTAGTGGAATTAGGTTTAATAAAAAAATAA

Upstream 100 bases:

>100_bases
AACTAAATTTTATTGACAAACATTAAATTCAAATCTAAAATATTATCTACCTTTGTTATTGAAAGGTTTATACCTTTTTT
CTTAAATAAAAATGTAAAGT

Downstream 100 bases:

>100_bases
AAATTAAATAAATTTCAATCCTGTATCTGTCAGGATAAAAAATTCCAAATTCCAAACTCTGTTATGGGGTTTGGAATTTA
ATTTTTAAATACCTTTATGG

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MQNIPSVDLRDFLSDDPKRKQKFVNEIGSAFENIGFVALKGHFLDDKLVDELYGEIRKFFALPVETKHNYEIPGIGGQRG
YVSFGKEHAKGRKEGDLKEFWHFGQYVDKDSKWASEYPDNVEVKELPRFNEVGKEAYQMLEKTGIYVLRALALHLGLDEF
YFDEYAKEGNSILRPIHYPPITSEPENAIRAAAHGDINLITLLMGAQGKGLQVQNHNGDWIDAIAADDELVINVGDMLSR
HTNNKLKSTIHQVVNPPRELWGTSRYSVPFFMHPVSDMRLDCLENCIDEENPKKYEDISAGEFLHERLVELGLIKK

Sequences:

>Translated_316_residues
MQNIPSVDLRDFLSDDPKRKQKFVNEIGSAFENIGFVALKGHFLDDKLVDELYGEIRKFFALPVETKHNYEIPGIGGQRG
YVSFGKEHAKGRKEGDLKEFWHFGQYVDKDSKWASEYPDNVEVKELPRFNEVGKEAYQMLEKTGIYVLRALALHLGLDEF
YFDEYAKEGNSILRPIHYPPITSEPENAIRAAAHGDINLITLLMGAQGKGLQVQNHNGDWIDAIAADDELVINVGDMLSR
HTNNKLKSTIHQVVNPPRELWGTSRYSVPFFMHPVSDMRLDCLENCIDEENPKKYEDISAGEFLHERLVELGLIKK
>Mature_316_residues
MQNIPSVDLRDFLSDDPKRKQKFVNEIGSAFENIGFVALKGHFLDDKLVDELYGEIRKFFALPVETKHNYEIPGIGGQRG
YVSFGKEHAKGRKEGDLKEFWHFGQYVDKDSKWASEYPDNVEVKELPRFNEVGKEAYQMLEKTGIYVLRALALHLGLDEF
YFDEYAKEGNSILRPIHYPPITSEPENAIRAAAHGDINLITLLMGAQGKGLQVQNHNGDWIDAIAADDELVINVGDMLSR
HTNNKLKSTIHQVVNPPRELWGTSRYSVPFFMHPVSDMRLDCLENCIDEENPKKYEDISAGEFLHERLVELGLIKK

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=299, Percent_Identity=27.0903010033445, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 36093; Mature: 36093

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNIPSVDLRDFLSDDPKRKQKFVNEIGSAFENIGFVALKGHFLDDKLVDELYGEIRKFF
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHH
ALPVETKHNYEIPGIGGQRGYVSFGKEHAKGRKEGDLKEFWHFGQYVDKDSKWASEYPDN
HCCCCCCCCCCCCCCCCCCCCHHHCHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCC
VEVKELPRFNEVGKEAYQMLEKTGIYVLRALALHLGLDEFYFDEYAKEGNSILRPIHYPP
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCCCCC
ITSEPENAIRAAAHGDINLITLLMGAQGKGLQVQNHNGDWIDAIAADDELVINVGDMLSR
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCEEEEEECCCCEEEEHHHHHHH
HTNNKLKSTIHQVVNPPRELWGTSRYSVPFFMHPVSDMRLDCLENCIDEENPKKYEDISA
HCCHHHHHHHHHHHCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHCCHH
GEFLHERLVELGLIKK
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQNIPSVDLRDFLSDDPKRKQKFVNEIGSAFENIGFVALKGHFLDDKLVDELYGEIRKFF
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHH
ALPVETKHNYEIPGIGGQRGYVSFGKEHAKGRKEGDLKEFWHFGQYVDKDSKWASEYPDN
HCCCCCCCCCCCCCCCCCCCCHHHCHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCC
VEVKELPRFNEVGKEAYQMLEKTGIYVLRALALHLGLDEFYFDEYAKEGNSILRPIHYPP
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCCCCC
ITSEPENAIRAAAHGDINLITLLMGAQGKGLQVQNHNGDWIDAIAADDELVINVGDMLSR
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCEEEEEECCCCEEEEHHHHHHH
HTNNKLKSTIHQVVNPPRELWGTSRYSVPFFMHPVSDMRLDCLENCIDEENPKKYEDISA
HCCHHHHHHHHHHHCCHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCHHHCCHH
GEFLHERLVELGLIKK
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1956290 [H]