Click here to switch to the map view.

The map label for this gene is qor [C]

Identifier: 146300591

GI number: 146300591

Start: 3373896

End: 3374867

Strand: Reverse

Name: qor [C]

Synonym: Fjoh_2841

Alternate gene names: 146300591

Gene position: 3374867-3373896 (Counterclockwise)

Preceding gene: 146300592

Following gene: 146300589

Centisome position: 55.35

GC content: 36.63

Gene sequence:

>972_bases
ATGAAAGCAGCAGTAGTTTATAAAAAAGGTGAATTGCCTAAATATGCAGAATTTCCAGAACCAATAACAGCAAATGAAAG
TGAGATTTTAATCTCGGTTAAAGCCGTGGCAATTACAAATCTGGATAAAGGAATTGTGAGCGGACAGCATTATTCTTCAG
AAAATGATAATCAAAACGGAACTGTAATTGGCAGTGACGCAATTGGTTTACTAGAAAATGGAACGAAAGTTTACGCCCGT
GGTATTTCTGGAACAATTGCAGAGAAAGCTTTAGTTGAGAAAAACAGAATGGTTGTGTTACCAGAAGGAATCGATGATGC
AGTGGCGGCAGCCATTCCAAATGCGGTTGCAGGCTCAGCAATGGCACTTCGTTTTAAAGCCGGAATACAGCCCGGAGAAA
CGGTTTTAATTAACGGAGCAACAGGATTTACGGGACAGATGGCAATTCAGATTGCAAAACATTACGGTGCAAAGAAAATA
ATCGTAACTGGAAGAAATGAAAAAACACTTCAAAATCTTTTAGAATTAGGTGCTGATGAAATTATTTCTTTAAAACAAGA
TGATGAATCGTTTATTTCTCAGTTAAAAGAAATTCATAAAAATACTCCCATTGATATTGTTTTAGATTATTTGTGGGGAC
ATTCAGCTGAGCTTATTCTTTCTATTTTAAAAGGAAACGGGAACTTCACTCCCAAAACACGTTATGTTTCTGTAGGCTCT
ATGTCGGGAGATATAATTCAATTGTCAGCTTCTATTTTGCGCAGCGTTGATCTTCAGTTATCTGGTTCAGGTTTAGGCAG
CTGGACAAAAGAGGAAGTGAAATTATTGTTCTCAGAAATTCTTCCTGAAATGTTTCTTTTAGCTTCTCAAAACAAAATAA
AAGTAAATATCGAAAAAGTGAATTTAGCCGATATCGAAAAAATGTGGAACGCAGAAGTTCCAGATGGCAAACGATTGGTT
GTCTGGATCTAA

Upstream 100 bases:

>100_bases
CACACAAAAAATAACCTTTTTGAATTTGATAACAAATGTTATCGCCTGCCCGTAAACAGCCCTGTAATTTTGCTTCATAA
AATTTAATAATCTTAAAATT

Downstream 100 bases:

>100_bases
AAAGTTTTTTAAACACATAGAAACATAGTTTTTTATGTCTTAAAGAAGAATATAAAAAGAAACTAGTTTCTCACACATAG
CTATGTTTATTTATAGTAAG

Product: alcohol dehydrogenase

Products: NADP(+); Semiquinone. [C]

Alternate protein names: Quinone Oxidoreductase; Zinc-Containing Alcohol Dehydrogenase; Oxidoreductase; NAD(P)H Quinone Oxidoreductase PIG3 Family; NADPHQuinone Reductase; Zinc-Containing Alcohol Dehydrogenase Superfamily Protein; NADPH Quinone Oxidoreductase; LOW QUALITY PROTEIN Quinone Oxidoreductase; PIG3 Family NAD(P)H Quinone Oxidoreductase; NAD(P)H Quinone Oxidoreductase PIG3 Family Protein; Dehydrogenase; NADPH2Quinone Reductase; NADPHQuinone Reductase Related Zn-Dependent Oxidoreductase; Quinone Oxidoreductase Protein; Alcohol Dehydrogenase Zinc-Containing; Dehydrogenase/Oxidoreductase; Alcohol Dehydrogenase And Quinone Oxidoreductase; Alcohol Dehydrogenase Superfamily Zinc-Containing Protein; Zn-Dependent Oxidoreductase; NAD(P)H Quinone Oxidoreductase

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKAAVVYKKGELPKYAEFPEPITANESEILISVKAVAITNLDKGIVSGQHYSSENDNQNGTVIGSDAIGLLENGTKVYAR
GISGTIAEKALVEKNRMVVLPEGIDDAVAAAIPNAVAGSAMALRFKAGIQPGETVLINGATGFTGQMAIQIAKHYGAKKI
IVTGRNEKTLQNLLELGADEIISLKQDDESFISQLKEIHKNTPIDIVLDYLWGHSAELILSILKGNGNFTPKTRYVSVGS
MSGDIIQLSASILRSVDLQLSGSGLGSWTKEEVKLLFSEILPEMFLLASQNKIKVNIEKVNLADIEKMWNAEVPDGKRLV
VWI

Sequences:

>Translated_323_residues
MKAAVVYKKGELPKYAEFPEPITANESEILISVKAVAITNLDKGIVSGQHYSSENDNQNGTVIGSDAIGLLENGTKVYAR
GISGTIAEKALVEKNRMVVLPEGIDDAVAAAIPNAVAGSAMALRFKAGIQPGETVLINGATGFTGQMAIQIAKHYGAKKI
IVTGRNEKTLQNLLELGADEIISLKQDDESFISQLKEIHKNTPIDIVLDYLWGHSAELILSILKGNGNFTPKTRYVSVGS
MSGDIIQLSASILRSVDLQLSGSGLGSWTKEEVKLLFSEILPEMFLLASQNKIKVNIEKVNLADIEKMWNAEVPDGKRLV
VWI
>Mature_323_residues
MKAAVVYKKGELPKYAEFPEPITANESEILISVKAVAITNLDKGIVSGQHYSSENDNQNGTVIGSDAIGLLENGTKVYAR
GISGTIAEKALVEKNRMVVLPEGIDDAVAAAIPNAVAGSAMALRFKAGIQPGETVLINGATGFTGQMAIQIAKHYGAKKI
IVTGRNEKTLQNLLELGADEIISLKQDDESFISQLKEIHKNTPIDIVLDYLWGHSAELILSILKGNGNFTPKTRYVSVGS
MSGDIIQLSASILRSVDLQLSGSGLGSWTKEEVKLLFSEILPEMFLLASQNKIKVNIEKVNLADIEKMWNAEVPDGKRLV
VWI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194239674, Length=257, Percent_Identity=28.4046692607004, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13236495, Length=257, Percent_Identity=28.4046692607004, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=310, Percent_Identity=27.4193548387097, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.5.5 [C]

Molecular weight: Translated: 34872; Mature: 34872

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVVYKKGELPKYAEFPEPITANESEILISVKAVAITNLDKGIVSGQHYSSENDNQNG
CCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCHHHCCCCCCCCCCCCCCC
TVIGSDAIGLLENGTKVYARGISGTIAEKALVEKNRMVVLPEGIDDAVAAAIPNAVAGSA
EEEECCCCEECCCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCHHHHHHCCCHHCCCE
MALRFKAGIQPGETVLINGATGFTGQMAIQIAKHYGAKKIIVTGRNEKTLQNLLELGADE
EEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHH
IISLKQDDESFISQLKEIHKNTPIDIVLDYLWGHSAELILSILKGNGNFTPKTRYVSVGS
EEEECCCHHHHHHHHHHHHCCCCHHEEEHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECC
MSGDIIQLSASILRSVDLQLSGSGLGSWTKEEVKLLFSEILPEMFLLASQNKIKVNIEKV
CCCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
NLADIEKMWNAEVPDGKRLVVWI
CHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MKAAVVYKKGELPKYAEFPEPITANESEILISVKAVAITNLDKGIVSGQHYSSENDNQNG
CCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCHHHCCCCCCCCCCCCCCC
TVIGSDAIGLLENGTKVYARGISGTIAEKALVEKNRMVVLPEGIDDAVAAAIPNAVAGSA
EEEECCCCEECCCCCEEEEECCCCHHHHHHHHCCCCEEEEECCCCHHHHHHCCCHHCCCE
MALRFKAGIQPGETVLINGATGFTGQMAIQIAKHYGAKKIIVTGRNEKTLQNLLELGADE
EEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHH
IISLKQDDESFISQLKEIHKNTPIDIVLDYLWGHSAELILSILKGNGNFTPKTRYVSVGS
EEEECCCHHHHHHHHHHHHCCCCHHEEEHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECC
MSGDIIQLSASILRSVDLQLSGSGLGSWTKEEVKLLFSEILPEMFLLASQNKIKVNIEKV
CCCCHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
NLADIEKMWNAEVPDGKRLVVWI
CHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.065 {1,4-benzoquinone}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.26 {1,4-naphthoquinone}} 0.0024 {1,2-naphthoquinone}} [C]

Substrates: NADPH; Quinone [C]

Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]

General reaction: Oxidation; Reduction [C]

Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA