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The map label for this gene is yodT [H]

Identifier: 146299852

GI number: 146299852

Start: 2509396

End: 2510775

Strand: Direct

Name: yodT [H]

Synonym: Fjoh_2094

Alternate gene names: 146299852

Gene position: 2509396-2510775 (Clockwise)

Preceding gene: 146299851

Following gene: 146299853

Centisome position: 41.16

GC content: 37.54

Gene sequence:

>1380_bases
ATGATTAAATCCTTAATACAATCTATGGCAGTATGCCCGGATATGAATAAAGTTTACCCTAAAATTGATTACGGTAAAGG
TGTATATGTATATGACCAAAATGGTAAAAAATATTTAGATGCATCGTCAGGATCTTCGGCAGTTTCAAATATAGGACACG
GGAGAACTGAAATTGCAGATGTAATTCACCAGCAGGTTTCTAAAATATCTGTTTTGCCAACACACGCTTTTAACTCAGAT
GTAGTCGAAAGTTATTTAGATCGTCTTGTTTCTTTTGCGCCAGCAGGATTTAGCAAAGCGTGGACAGTAATGAGCGGGAC
TGAAGCGGTAGAAAGTGCAGTTAAACTTGCTTTACAATTTCATCAGTTAAGAGGAGATTTCAACCGATACAAAGTAATTT
CAAGATGGAATACTTATCATGGAAACTCAGTTTTTATGCTGGATGTAGGAGGAATGAAAATCAGAAGAGAACTTTACAAG
CAGTGGCTTAATAATTTTCCTCACATTTCTCCGGCTTACAATTACAGAAGACCGGAAGAATTAAATGAAGATCAGTTTGT
TCAAAGTTTACTGGCAGAGTTTGAAACTACAATTATTGAAGAAGGTGCAGAATCAATAGCTGCTTTTGTGGCAGAACCTG
TAATCGCCTCAGCAATGGGTGCAGTACCGCCTCCGGCAAATTATTTTGCAGGAATCTCAAGAATATGTAAAAAATACGGA
ATCCTTTTTATTACAGACGAAATCCTGACAGGTTTTGGAAGAACAGGTAAAAATTTTGGTATGGATAATTATGGTGTTGT
ACCAGATATTATCGCAGCCGGAAAAGGAATGAGCGGCGGTTATTTTCCTTTATCAGCCGTAATTGCTTCAGCATATGTTA
CACAGCCTTTTATTGACACAAAAACGCCATTTCTTGGCGGTTACACTTTTGCTTGTAATCCGGTTGGCTGTGCTGTTGGA
AATAAAGTAATGGACATTTTAGAAAGAGAAGATGTTATAGGTAACGCTAAGAGAATGGGAGCTTTGTTTCTGGAAAAACT
AAAAGCATTATACGAGTTCGAAATCGTTGGTGATGTTCGCGGCGAAGGGCTGTTATGCGGTGTTGAAATTGTTCAAAACC
AAAGCACAAAAGAGCCATTTCCGGTTTCTATGGGAATTTCAAAAATGCTGGGCGAAAAAGCAATTCAAAAAGGAGTTGTC
CTGTATCCAGGAAGAGGTTCTGTAGACGGGGTTCTGGGAGATCATATTCAAATTTCGCCGCCATTGGTAATTAACGAGGA
GCAATTGGATGAAATTGTAGATGTTTTAAAAGAATGTTTAAAAGAAGTAATGTCTGAAATTAAAAAAACTACCCTGAATT
ATGAAAGTATTGAGTCTTAA

Upstream 100 bases:

>100_bases
AACAAGCGGGGAAAAGCAAAATGCTATTAGAAGAGAATTTCTAAAATCAGTCCTTAAACTATTACAAACAGATATTAATT
AACCATTAAATAAAAACAAT

Downstream 100 bases:

>100_bases
GAAAGCTAAAACAGAAGAATTTTTAAATAGATTTTTAAACGAAAATCAAAACACTGATTCGAATACATTTTTTGAAGGAG
TACATATAAAATCTGAGAGT

Product: class III aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MIKSLIQSMAVCPDMNKVYPKIDYGKGVYVYDQNGKKYLDASSGSSAVSNIGHGRTEIADVIHQQVSKISVLPTHAFNSD
VVESYLDRLVSFAPAGFSKAWTVMSGTEAVESAVKLALQFHQLRGDFNRYKVISRWNTYHGNSVFMLDVGGMKIRRELYK
QWLNNFPHISPAYNYRRPEELNEDQFVQSLLAEFETTIIEEGAESIAAFVAEPVIASAMGAVPPPANYFAGISRICKKYG
ILFITDEILTGFGRTGKNFGMDNYGVVPDIIAAGKGMSGGYFPLSAVIASAYVTQPFIDTKTPFLGGYTFACNPVGCAVG
NKVMDILEREDVIGNAKRMGALFLEKLKALYEFEIVGDVRGEGLLCGVEIVQNQSTKEPFPVSMGISKMLGEKAIQKGVV
LYPGRGSVDGVLGDHIQISPPLVINEEQLDEIVDVLKECLKEVMSEIKKTTLNYESIES

Sequences:

>Translated_459_residues
MIKSLIQSMAVCPDMNKVYPKIDYGKGVYVYDQNGKKYLDASSGSSAVSNIGHGRTEIADVIHQQVSKISVLPTHAFNSD
VVESYLDRLVSFAPAGFSKAWTVMSGTEAVESAVKLALQFHQLRGDFNRYKVISRWNTYHGNSVFMLDVGGMKIRRELYK
QWLNNFPHISPAYNYRRPEELNEDQFVQSLLAEFETTIIEEGAESIAAFVAEPVIASAMGAVPPPANYFAGISRICKKYG
ILFITDEILTGFGRTGKNFGMDNYGVVPDIIAAGKGMSGGYFPLSAVIASAYVTQPFIDTKTPFLGGYTFACNPVGCAVG
NKVMDILEREDVIGNAKRMGALFLEKLKALYEFEIVGDVRGEGLLCGVEIVQNQSTKEPFPVSMGISKMLGEKAIQKGVV
LYPGRGSVDGVLGDHIQISPPLVINEEQLDEIVDVLKECLKEVMSEIKKTTLNYESIES
>Mature_459_residues
MIKSLIQSMAVCPDMNKVYPKIDYGKGVYVYDQNGKKYLDASSGSSAVSNIGHGRTEIADVIHQQVSKISVLPTHAFNSD
VVESYLDRLVSFAPAGFSKAWTVMSGTEAVESAVKLALQFHQLRGDFNRYKVISRWNTYHGNSVFMLDVGGMKIRRELYK
QWLNNFPHISPAYNYRRPEELNEDQFVQSLLAEFETTIIEEGAESIAAFVAEPVIASAMGAVPPPANYFAGISRICKKYG
ILFITDEILTGFGRTGKNFGMDNYGVVPDIIAAGKGMSGGYFPLSAVIASAYVTQPFIDTKTPFLGGYTFACNPVGCAVG
NKVMDILEREDVIGNAKRMGALFLEKLKALYEFEIVGDVRGEGLLCGVEIVQNQSTKEPFPVSMGISKMLGEKAIQKGVV
LYPGRGSVDGVLGDHIQISPPLVINEEQLDEIVDVLKECLKEVMSEIKKTTLNYESIES

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI226442705, Length=435, Percent_Identity=31.9540229885057, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI37574042, Length=435, Percent_Identity=31.9540229885057, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI13994255, Length=451, Percent_Identity=29.490022172949, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=32.1518987341772, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI24119277, Length=439, Percent_Identity=28.7015945330296, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI4557809, Length=424, Percent_Identity=28.0660377358491, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI284507298, Length=236, Percent_Identity=31.7796610169492, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=484, Percent_Identity=23.1404958677686, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38679950, Length=484, Percent_Identity=23.1404958677686, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38679946, Length=484, Percent_Identity=23.1404958677686, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI145693181, Length=417, Percent_Identity=27.0983213429257, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789016, Length=449, Percent_Identity=28.2850779510022, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788044, Length=424, Percent_Identity=26.1792452830189, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787560, Length=417, Percent_Identity=29.9760191846523, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1789759, Length=423, Percent_Identity=26.241134751773, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786991, Length=433, Percent_Identity=27.0207852193995, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=29.3159609120521, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25144271, Length=417, Percent_Identity=30.9352517985612, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32564660, Length=443, Percent_Identity=28.4424379232506, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=448, Percent_Identity=28.3482142857143, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25144274, Length=233, Percent_Identity=35.1931330472103, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=480, Percent_Identity=25.4166666666667, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=424, Percent_Identity=31.1320754716981, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6324386, Length=456, Percent_Identity=27.1929824561404, Blast_Score=123, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6324432, Length=434, Percent_Identity=25.8064516129032, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=29.9539170506912, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21357415, Length=421, Percent_Identity=31.353919239905, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI161085790, Length=454, Percent_Identity=29.295154185022, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28574759, Length=447, Percent_Identity=29.7539149888143, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI281366494, Length=466, Percent_Identity=24.0343347639485, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24667139, Length=466, Percent_Identity=24.0343347639485, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24667143, Length=466, Percent_Identity=24.0343347639485, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50391; Mature: 50391

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSLIQSMAVCPDMNKVYPKIDYGKGVYVYDQNGKKYLDASSGSSAVSNIGHGRTEIAD
CHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCHHHHHH
VIHQQVSKISVLPTHAFNSDVVESYLDRLVSFAPAGFSKAWTVMSGTEAVESAVKLALQF
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHHHHHH
HQLRGDFNRYKVISRWNTYHGNSVFMLDVGGMKIRRELYKQWLNNFPHISPAYNYRRPEE
HHHHCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LNEDQFVQSLLAEFETTIIEEGAESIAAFVAEPVIASAMGAVPPPANYFAGISRICKKYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
ILFITDEILTGFGRTGKNFGMDNYGVVPDIIAAGKGMSGGYFPLSAVIASAYVTQPFIDT
EEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
KTPFLGGYTFACNPVGCAVGNKVMDILEREDVIGNAKRMGALFLEKLKALYEFEIVGDVR
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCC
GEGLLCGVEIVQNQSTKEPFPVSMGISKMLGEKAIQKGVVLYPGRGSVDGVLGDHIQISP
CCCEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEECC
PLVINEEQLDEIVDVLKECLKEVMSEIKKTTLNYESIES
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MIKSLIQSMAVCPDMNKVYPKIDYGKGVYVYDQNGKKYLDASSGSSAVSNIGHGRTEIAD
CHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEECCCCEEEECCCCCHHHHHCCCCHHHHHH
VIHQQVSKISVLPTHAFNSDVVESYLDRLVSFAPAGFSKAWTVMSGTEAVESAVKLALQF
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHHHHHH
HQLRGDFNRYKVISRWNTYHGNSVFMLDVGGMKIRRELYKQWLNNFPHISPAYNYRRPEE
HHHHCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LNEDQFVQSLLAEFETTIIEEGAESIAAFVAEPVIASAMGAVPPPANYFAGISRICKKYG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
ILFITDEILTGFGRTGKNFGMDNYGVVPDIIAAGKGMSGGYFPLSAVIASAYVTQPFIDT
EEEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
KTPFLGGYTFACNPVGCAVGNKVMDILEREDVIGNAKRMGALFLEKLKALYEFEIVGDVR
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCC
GEGLLCGVEIVQNQSTKEPFPVSMGISKMLGEKAIQKGVVLYPGRGSVDGVLGDHIQISP
CCCEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEECC
PLVINEEQLDEIVDVLKECLKEVMSEIKKTTLNYESIES
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]