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The map label for this gene is tycC [H]

Identifier: 146299851

GI number: 146299851

Start: 2502107

End: 2509339

Strand: Direct

Name: tycC [H]

Synonym: Fjoh_2093

Alternate gene names: 146299851

Gene position: 2502107-2509339 (Clockwise)

Preceding gene: 146299850

Following gene: 146299852

Centisome position: 41.04

GC content: 31.4

Gene sequence:

>7233_bases
ATGAGCAAAAAAATAATTCATACCGTATTTGAAAGTGTAGTACAAAGCCAAGGCAGCAATATTGCTTTGCAAGGCGATCA
AGGAAATATATCATATCAGGAGCTAAATCAATATTCAAATAAGCTGGCGCATCTTTTGCTTAATAATAACATATCTAGAA
ATGATATTGCAACTGTTTATTTTTCAGATCCGAGATTACAGGTTATTTCATTACTTGGTGCTTTAAAGTCAGGAGCGATT
TATCTGCCAATTGATAAAAAGTACAAACGCAATCATTGGGAAGAATTATATACCACAATACTTCCAAAAGTATATATTAC
TGCTTCAGAAGATCTTCCGCTGTTACATCAATTCAGTGACTCGTTCGATTATTCTATTCCATTTATCATAACATTATTAA
TTGATAGCCATGGAGCGTTAAAACATAAATTGTATGCCTATTCAAATAAAACATACGTAGATGTAACGAGCAAAACTCCT
TTATCTGACGAAAATCCAAATTTAGAATTTGGAGAGAATGATCCTAATTATATTTATTTCACTTCAGGTTCAACCGGCAA
TCCAAAAGCCGTTTTGGGCTGTCATAAAAGTCTGAGTCATTTTATACACTGGGAATCTAAAGAGCTGGGTATAAAAGAAT
CAGATAAAATAGGATTACTGCCTTCTTTTTCATTTGATGCTTCAATCCAGGCTGTTTTTATGGCGTTGATTAACGGAAGC
ACACTTTGTTTAATTAATTCTGAAACGAAAGAAGATATTATTCAACTGCAAAACTGGATAAGAAATTATAATATTACGGT
GCTTCACATGGTGCCAACCTTATTCAGGATTTTGAGTATTTATTCTGAAGGTAAAGACAAAAATCTTTCATTTCCTGATT
TGAAATACATATTGCTGGCAGGAGAAAAATTATATAACAAAGATGTTGTAAACTGGAGAGAATGTCACGGAAACAACACA
GAAATTATCAATTTCTACGGAACTACAGAAGCTACAATTCTTAGCACATTTTATAGAATAGAACAAGAACTTCAAGGGGA
ATTATCTGATGTGTTTTGTGTTGGACAGCCAATTTCAAATACTGCCATATTAATTTTAAATAAAGAAAATAAACTTTGCA
AGATTGGCGAAGTAGGAAGTATTTACATAAAAACGCCATTTTTAACAAAAGGATATTACAAAAATCCGGAGCTGACAGCT
GATAAATTTATACAAAATCCGTTAACTGCTTCAACAGATATTATTTATAAAACAGGCGATTACGGAAAATATGATTCGCA
GCGAAATACTATCGTTACAGGAAGAGAAGATGGTTTGGTAAAAATTAATGGGGTTCGTATTGATATTAATACAATCGAGC
AGACTATCCTGAAATTAAAAGAGGTCGATATGGTAAAATGCCTTACCTATCAACAAGATTTACTAAATGTAATTTTGGTA
TGTTTTTATAAATCAGCAGCTGTTAATGAAAACGACATTAGAAAACACTGTCTTGAGTATTTATCTCAATATGAAATGCC
TTCTCGTTTTATTGCCCTTGACGAAGTGCCAATTAATGCTAATGGTAAAATTGATCCGGTTGTCCTGAAAAAAATAATCG
ACGATACATTAGCTGCAGATAATAATGAAACTGAAGATGAAACTCAAGCTGATGAAACAGAACAAAAACTAATTCAGATC
TGGAAAGAAATATTAAATGTTGAAAAAATCAGACTAAAGGATAACTATTTGTTTTTAGGAGGAAACAGTATTAAACTTAT
TCAATTAAGACTTAGAATTCAGCAAAATTTTGATGTAGAACTCAGCATTTATGATTTATTTACTAATCCGGTTTTAAAAG
AACAGGCAAAACTAATCGCAGAATCGAAGAAATCTGTTTTCGAGGCTATTCCACAAGTACAAGCTCAGGAATATTACAAT
TTATCTTCAACACAATACAGAATGTGGGTTGTTTCGCAAATAGAAAGCAGTTCTATTGCATATAATATGCCTAGTGCTTT
CTTATTAAAGGGAGAAATTGACAAGTTAAAATTCAACGAAGCATTTAAAAATATTATTGAACGTCATGAAATCCTGCGAA
CTTTTTTCAAATCAAATCAGGATGGAGAAGTTCACCAATATATTACACCAGTAAACGAAGCCGCTTTTGAAATTACTGAA
AAGGATCTGTCGCATTTTAATTCATTAGAAGAAATTAAACCTTACCTAATCAGCTTAAACGCAGAACCATTTAATTTAGA
AGAAGCACCACTTTTAAGAGCTTATTTAATTAAAGTAAATGAAAATCAGCATGTATTCTATTTTACAATGCACCATATTA
TTGGCGACGGATGGTCATCATTAATTTTGCTTAAAGAAATAATCAGCACATATAATAGCTTATTAAATGGAAACCAGACT
GAATTAGAAGGGTTAAATATTCAGTTTAAAGACTATGTAGCATGGTCACAAAATGAAACCCATTTAGAGAAAAACAAAAT
TTCTGAAAACTATTGGTTAGATCAATTTTCTGGTGAATTGCCAGTATTAGAACTGCCAGGTTTTAAAAAACGCCCTTTAA
TAAAAACTAATAACGGGAACAAGATAGAACACGTTTATTCGGCAGAATTTACTAAAAAATTAAAGTCATTTTCAGAAACT
CAAAATGTTACTTTATTCATGACTTTAATGGCAGGAATAAATACACTTTTGTCAAGATATTCAGGGCAGGATGATATTAT
TGTTGGAACGCCGGTTGCAGGAAGAGAGCACCCGGATTTAGAAAACCAGATTGGTCCTTATTTAAATACTGTTGCTATCC
GGACAAAACTAGAAGAGCAGGAAACTTTTACTTCATTATTGTTAAAAGAAAAGCAGCTATTATTAAACTCATATCAGCAT
CAGGATTATCCTTTTGATGAATTGGTATGGAAATTAAATTTAGCTCAGGATAGCAGCCGTTCATTTTTATTTGATGTTTT
AGTAGTATTACAAAACCAAAACCAGGTTGCTAATTTAAATATCAGCGAAGAATTAAGCGGTATAAAAATAGAACCAGTTG
ATTTTGAAAGCAATTTTTCAAAGTTTGACCTGAACTTTATGTTCATCGAAGCAGAAAACTTAAACCTTTCAATTACTTAT
AATACAGATATCTACGATCAGTTTTTAATTAAAAGAATGTTTCAGCATTTCGAAATTCTTTTAAACCAGTTTACTGCTAA
TCCTGATGTCGCTGTCAATAAAGTTGATTATCTGACAGAAAACGAAAAAACACAGTTATTGTTTGATTTCAATGATTTGA
TTGTAGAGTATCCAAAAGATAAAACTATTGTGGATTTGTTTGAGGAACAAGCTGCTAATAATCCTAATGTTACAGCAATT
GCATTTGAGGAAAAAAATATTACTTACGCAGATTTATCTAAAGAAGTAAATGCATTAGCAGCACAGCTTTCTGAACAAAA
TGTTGAAAGAGGAGATAAAATTATAATTTGTTTTAACAGCCATATCGAAAAAGCAATAACAGGACTATTGGCTGTTTTAA
AAATAGGAGCGGTATATGTTCCTGTAGATTCAGATTATCCATTAGAAAGAATCCGTTTTATTGTTGAGGATACCAAAGCA
AAATTCGTTATTACAAACAGTTTAGATGCTGTTATTTTTAAAGATGTAAATGCAGATATAATTGCATTAGACGAACAAAA
AGAATTTGAAAACAGTAAAGAACTTGTTTTTGAAAAAATCAACATTTCAGATAATGCTTATGTGATTTATACCTCAGGAT
CTACGGGAAATCCTAAAGGAGTAGTGGTAAGCCATAGAAATATAAACGATTATGTTTTTGGATTAAAATCTAAAATTCAA
ATACAAAAGAATGACTCTTTTGCCTTAATGTCTACATTGGCTACAGATTTAGGAAACACAGTTCTTTTTGGTTCTTTACT
GACTGGAAAAACGCTGCATTTGTTTTCGAAAGACAGTTTAAGAGATGTAAATTATATTCAGGAATATTATGAAAATCATT
CTATCGATTGTATTAAAATTGTGCCAAGTTATTGGAAATCATTAAACTTAAAAAGCCAGTCTCCTAACAAGATGATCATT
TTTGGCGGAGAAGAGCTGACCGTTGATGTTGTAGAACAAATCAAAAACGAAAAGCCTGCTATTACCATTGTTAATCATTA
CGGACCTACCGAAACAACTATTGGGAAATTACTTCATGTTGTTGATCTGGAAAATTCATACGATCGTATTCCAATTGGAA
GACCGTTCTCGAATACCAATGTATTTGTAGTAGATCAGAACTTTTTACTATGTCCTGTAGGTGTTGAAGGAGAATTGGTT
ATTGGGGGAGATGGTGTCTCAAATGGTTATTTGAATAATCTGCAATTAACAGAAACGCAATTTGTTAAAGATACACTTCT
TCAAACAGAAGCGAAACTTTACAAAACCGGAGATAAAGTAAAACAATTTCCAAATGGTGATATCGAATACTTAGGACGAT
TTGACGATCAGGTAAAAATAAGAGGGCACAGGATTGAATTAGGAGAAATAAGCAGAAATCTTGCATTAATCGAAGGCATA
AGCCAATCTATTGTAACAGTAGGCCAAAATAACGAGGAGAAGTTTTTAATTGCTTATTACGTTTCAGAAACACAGTTAGA
TAAAAAAGAAATTCAGTCCAGTCTATCTAAAGTACTGCCAGAATATATGGTGCCGTCGTATTATGTGAAGTTAGAAAGTC
TGCCTTTAACATCGAATGGAAAAATCAACAGAAAAGCACTTCCTAAAATTTCTGAGAAAGACATTATCCGAAAAGAATAT
GTAGGGCCAAGAAATAAAACAGAAGAAAAATTAGTTCAAATCTGGCAGGAAATACTAAAAGTAGAAACAATTGGTGTAAC
TGATAATTTCTTTAATCTTGGCGGACACAGTTTATTAGTTGTTAGAATTCTCAACTTAATCAAAAAAGAAATAGGCTTAA
ATATTTCTGTAAAAACATTTTTTGAAAATCCTACTATTGATGCCTTATCAGGACAGTTAAAAGGAAAAGAAACAGAATCT
TTCTTTATTGAAAAAATTGCTCCTGCTGATTCTTATCCGGTAACGGCTTCGCAAAAAAAGTTTTGGTTAATCAGCCAGTT
TGAAGATGCTTCTTTAGCTTATAATATGCTGACTGTTTTTAGACTTGAAGGAAATTTAATTATTCCAAAATTCCAGGAAT
CGTTTATCCATCTTATCGAAAGACACGAAAGTTTAAGAACTTCTTTCAAACTTAATGAAGATGAAGAATTAAGACAGTTT
ATAGTGCCTGTTGAAGATCTGGATTTTAGTATCAATTATGTTGATCTCAGCTCTAATGAAACAACCGAAGAAAATTTAGC
CGCTTATGTAGAAAAAGAAAATGCGATTCGATTTGATTTAGAAAAAGCACCTCTGGTTCGTGCTTCATTAATAAAAGCCG
CTGAAGGTAAATTCGTATTCTTTATATCAATGCATCACATTATTGGAGACGGCTGGTCATCTGAATTATTAGTTGGAGAA
GTTGTTTCTATCTACAATGCTCTTATTCAGGAAAGAGAAGTGAATTTACCAGAATTAAGAATTCAGTATAAAGATTATGC
AGCCTGGCTTAACAATGAAATTGAAAAAGAAGGATATAAAATTTCAGAGAAATATTGGTTAGATCAATTTTCAGGAAATC
TTCCAACTATTGAACTGCCTGGTTCTAAAATAAGACCTTCAGTAAAAACGTATAATGGAGACTATTTAGGTTATGAGTTT
TCAGACAGTTTTTCGCAACAGTTAAGAGATTTCTCTACAGAGCAGAATGTATCATTGTTCATGGTATTAACAGCTGGAAT
CAACACGTTGTTAAGTAAATATACAGGAGAAAATGATATTGTTGTAGGAACTCCGGTTGCAGGAAGAGAACATCCTGATT
TAGAAAATCAAATAGGACTTTATTTAAATACGCTGGCTCTAAGAACCAAAATAAATCAAAAAAACAGTTTCTTAGAATTA
TTGCAGCATGAAAAAGAAGTTATTCTGGGAGCTTACGAAAATCAGCTTTATCCGTTTGATGAATTGATTGATAAACTGCA
GTTAAAAAGAGACAGAAGCAAAGCCTTATTATTTGATATACTGATTGTTTTACATAATCAGACAAAATTAAATATGGAAG
ATGATGAAAAACTGGTAGACCTTTACATTAAACCTTATGCCTCAACACGTAAAACTTCGCAGTTTGATTTGTCATTTAGA
TTTTCAGACAATGAGAGACTATATCTTGAAATAAATTACAATACAGATATCTACGAAAAATCATTTATCGAAAAAGTATT
TACACATTTTGAAGCACTGGTTTTTCAATTAATAACCAAACCAGAAATAAAATTAGAGCTTGTTGATTTTCTATCTGAAG
AAGATAAAAGAGAAATCGAAATGAGTGATTACTGGAAATCGGTTTTCAAAAATGAATTTTCAAATGTTGTATTTCCTTTT
GAAAAACAAACTCTTGAAAAATTGGATAAGTCAGGAGCTCAGTTTCAGTTTTCTATTAATGAAGAATTAAAAGAAGGATT
AGAAAAATTATCAGATTCAAACAGTGGTGATCTTTTTACTTCAGTATTGTTTTCTCTAAAAACGACAGTACGAAAATATA
TTGAAAATGATGAGGTTGCATTTCATATTTCAATTCCGGAAGAAGCACCTAATGAATGGCATAAATTGGATTTACCATTT
GTTACCAATATCAGTAACGACGAATTACTGCTGGATGTTTACAACGATTTGAATTTTAGAATAACTGAGTTAAAGGAAAA
TCTTTTTACTGATTTTCAATTGGCAAAAAAAACGGCTGATTCTTTTTATAAACAAAATGAAGCTGCAGTTTTCAATATCA
AATACAATTATCATAAAAATCATGATTTTCAGGATTGGGTGCAGTTAGAATCAACAGAAGGAAACGAGTTTGAAAAAAGT
ATCATTTTTAAGGAAGAAGCTGCAATTACTCATAATATGTCATTCGATTTTTATGAAAATGAATCTAGTGTTACCTGTGT
ACTAACTTATAATGCAGATAAATACGATAAAAATCAGGTTGTGTTATTTATAGAAAGATTCAAAATTGTAATGAACCAGA
TAGCGAATACCAAAGAACAATTCAGCAAGCTGACAACTCGTGAGATCAGTTTTAATTATCAAAAAGAAAAACAAGCGGGG
AAAAGCAAAATGCTATTAGAAGAGAATTTCTAA

Upstream 100 bases:

>100_bases
TTTTAAAATGAATCAGCATTGGAAAAACTGGAAACCAAATATAATTTTTGGATTGTTTCTAACATATAAAAAATGCTTCT
AATAAATAAAATATATACAA

Downstream 100 bases:

>100_bases
AATCAGTCCTTAAACTATTACAAACAGATATTAATTAACCATTAAATAAAAACAATATGATTAAATCCTTAATACAATCT
ATGGCAGTATGCCCGGATAT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2410; Mature: 2409

Protein sequence:

>2410_residues
MSKKIIHTVFESVVQSQGSNIALQGDQGNISYQELNQYSNKLAHLLLNNNISRNDIATVYFSDPRLQVISLLGALKSGAI
YLPIDKKYKRNHWEELYTTILPKVYITASEDLPLLHQFSDSFDYSIPFIITLLIDSHGALKHKLYAYSNKTYVDVTSKTP
LSDENPNLEFGENDPNYIYFTSGSTGNPKAVLGCHKSLSHFIHWESKELGIKESDKIGLLPSFSFDASIQAVFMALINGS
TLCLINSETKEDIIQLQNWIRNYNITVLHMVPTLFRILSIYSEGKDKNLSFPDLKYILLAGEKLYNKDVVNWRECHGNNT
EIINFYGTTEATILSTFYRIEQELQGELSDVFCVGQPISNTAILILNKENKLCKIGEVGSIYIKTPFLTKGYYKNPELTA
DKFIQNPLTASTDIIYKTGDYGKYDSQRNTIVTGREDGLVKINGVRIDINTIEQTILKLKEVDMVKCLTYQQDLLNVILV
CFYKSAAVNENDIRKHCLEYLSQYEMPSRFIALDEVPINANGKIDPVVLKKIIDDTLAADNNETEDETQADETEQKLIQI
WKEILNVEKIRLKDNYLFLGGNSIKLIQLRLRIQQNFDVELSIYDLFTNPVLKEQAKLIAESKKSVFEAIPQVQAQEYYN
LSSTQYRMWVVSQIESSSIAYNMPSAFLLKGEIDKLKFNEAFKNIIERHEILRTFFKSNQDGEVHQYITPVNEAAFEITE
KDLSHFNSLEEIKPYLISLNAEPFNLEEAPLLRAYLIKVNENQHVFYFTMHHIIGDGWSSLILLKEIISTYNSLLNGNQT
ELEGLNIQFKDYVAWSQNETHLEKNKISENYWLDQFSGELPVLELPGFKKRPLIKTNNGNKIEHVYSAEFTKKLKSFSET
QNVTLFMTLMAGINTLLSRYSGQDDIIVGTPVAGREHPDLENQIGPYLNTVAIRTKLEEQETFTSLLLKEKQLLLNSYQH
QDYPFDELVWKLNLAQDSSRSFLFDVLVVLQNQNQVANLNISEELSGIKIEPVDFESNFSKFDLNFMFIEAENLNLSITY
NTDIYDQFLIKRMFQHFEILLNQFTANPDVAVNKVDYLTENEKTQLLFDFNDLIVEYPKDKTIVDLFEEQAANNPNVTAI
AFEEKNITYADLSKEVNALAAQLSEQNVERGDKIIICFNSHIEKAITGLLAVLKIGAVYVPVDSDYPLERIRFIVEDTKA
KFVITNSLDAVIFKDVNADIIALDEQKEFENSKELVFEKINISDNAYVIYTSGSTGNPKGVVVSHRNINDYVFGLKSKIQ
IQKNDSFALMSTLATDLGNTVLFGSLLTGKTLHLFSKDSLRDVNYIQEYYENHSIDCIKIVPSYWKSLNLKSQSPNKMII
FGGEELTVDVVEQIKNEKPAITIVNHYGPTETTIGKLLHVVDLENSYDRIPIGRPFSNTNVFVVDQNFLLCPVGVEGELV
IGGDGVSNGYLNNLQLTETQFVKDTLLQTEAKLYKTGDKVKQFPNGDIEYLGRFDDQVKIRGHRIELGEISRNLALIEGI
SQSIVTVGQNNEEKFLIAYYVSETQLDKKEIQSSLSKVLPEYMVPSYYVKLESLPLTSNGKINRKALPKISEKDIIRKEY
VGPRNKTEEKLVQIWQEILKVETIGVTDNFFNLGGHSLLVVRILNLIKKEIGLNISVKTFFENPTIDALSGQLKGKETES
FFIEKIAPADSYPVTASQKKFWLISQFEDASLAYNMLTVFRLEGNLIIPKFQESFIHLIERHESLRTSFKLNEDEELRQF
IVPVEDLDFSINYVDLSSNETTEENLAAYVEKENAIRFDLEKAPLVRASLIKAAEGKFVFFISMHHIIGDGWSSELLVGE
VVSIYNALIQEREVNLPELRIQYKDYAAWLNNEIEKEGYKISEKYWLDQFSGNLPTIELPGSKIRPSVKTYNGDYLGYEF
SDSFSQQLRDFSTEQNVSLFMVLTAGINTLLSKYTGENDIVVGTPVAGREHPDLENQIGLYLNTLALRTKINQKNSFLEL
LQHEKEVILGAYENQLYPFDELIDKLQLKRDRSKALLFDILIVLHNQTKLNMEDDEKLVDLYIKPYASTRKTSQFDLSFR
FSDNERLYLEINYNTDIYEKSFIEKVFTHFEALVFQLITKPEIKLELVDFLSEEDKREIEMSDYWKSVFKNEFSNVVFPF
EKQTLEKLDKSGAQFQFSINEELKEGLEKLSDSNSGDLFTSVLFSLKTTVRKYIENDEVAFHISIPEEAPNEWHKLDLPF
VTNISNDELLLDVYNDLNFRITELKENLFTDFQLAKKTADSFYKQNEAAVFNIKYNYHKNHDFQDWVQLESTEGNEFEKS
IIFKEEAAITHNMSFDFYENESSVTCVLTYNADKYDKNQVVLFIERFKIVMNQIANTKEQFSKLTTREISFNYQKEKQAG
KSKMLLEENF

Sequences:

>Translated_2410_residues
MSKKIIHTVFESVVQSQGSNIALQGDQGNISYQELNQYSNKLAHLLLNNNISRNDIATVYFSDPRLQVISLLGALKSGAI
YLPIDKKYKRNHWEELYTTILPKVYITASEDLPLLHQFSDSFDYSIPFIITLLIDSHGALKHKLYAYSNKTYVDVTSKTP
LSDENPNLEFGENDPNYIYFTSGSTGNPKAVLGCHKSLSHFIHWESKELGIKESDKIGLLPSFSFDASIQAVFMALINGS
TLCLINSETKEDIIQLQNWIRNYNITVLHMVPTLFRILSIYSEGKDKNLSFPDLKYILLAGEKLYNKDVVNWRECHGNNT
EIINFYGTTEATILSTFYRIEQELQGELSDVFCVGQPISNTAILILNKENKLCKIGEVGSIYIKTPFLTKGYYKNPELTA
DKFIQNPLTASTDIIYKTGDYGKYDSQRNTIVTGREDGLVKINGVRIDINTIEQTILKLKEVDMVKCLTYQQDLLNVILV
CFYKSAAVNENDIRKHCLEYLSQYEMPSRFIALDEVPINANGKIDPVVLKKIIDDTLAADNNETEDETQADETEQKLIQI
WKEILNVEKIRLKDNYLFLGGNSIKLIQLRLRIQQNFDVELSIYDLFTNPVLKEQAKLIAESKKSVFEAIPQVQAQEYYN
LSSTQYRMWVVSQIESSSIAYNMPSAFLLKGEIDKLKFNEAFKNIIERHEILRTFFKSNQDGEVHQYITPVNEAAFEITE
KDLSHFNSLEEIKPYLISLNAEPFNLEEAPLLRAYLIKVNENQHVFYFTMHHIIGDGWSSLILLKEIISTYNSLLNGNQT
ELEGLNIQFKDYVAWSQNETHLEKNKISENYWLDQFSGELPVLELPGFKKRPLIKTNNGNKIEHVYSAEFTKKLKSFSET
QNVTLFMTLMAGINTLLSRYSGQDDIIVGTPVAGREHPDLENQIGPYLNTVAIRTKLEEQETFTSLLLKEKQLLLNSYQH
QDYPFDELVWKLNLAQDSSRSFLFDVLVVLQNQNQVANLNISEELSGIKIEPVDFESNFSKFDLNFMFIEAENLNLSITY
NTDIYDQFLIKRMFQHFEILLNQFTANPDVAVNKVDYLTENEKTQLLFDFNDLIVEYPKDKTIVDLFEEQAANNPNVTAI
AFEEKNITYADLSKEVNALAAQLSEQNVERGDKIIICFNSHIEKAITGLLAVLKIGAVYVPVDSDYPLERIRFIVEDTKA
KFVITNSLDAVIFKDVNADIIALDEQKEFENSKELVFEKINISDNAYVIYTSGSTGNPKGVVVSHRNINDYVFGLKSKIQ
IQKNDSFALMSTLATDLGNTVLFGSLLTGKTLHLFSKDSLRDVNYIQEYYENHSIDCIKIVPSYWKSLNLKSQSPNKMII
FGGEELTVDVVEQIKNEKPAITIVNHYGPTETTIGKLLHVVDLENSYDRIPIGRPFSNTNVFVVDQNFLLCPVGVEGELV
IGGDGVSNGYLNNLQLTETQFVKDTLLQTEAKLYKTGDKVKQFPNGDIEYLGRFDDQVKIRGHRIELGEISRNLALIEGI
SQSIVTVGQNNEEKFLIAYYVSETQLDKKEIQSSLSKVLPEYMVPSYYVKLESLPLTSNGKINRKALPKISEKDIIRKEY
VGPRNKTEEKLVQIWQEILKVETIGVTDNFFNLGGHSLLVVRILNLIKKEIGLNISVKTFFENPTIDALSGQLKGKETES
FFIEKIAPADSYPVTASQKKFWLISQFEDASLAYNMLTVFRLEGNLIIPKFQESFIHLIERHESLRTSFKLNEDEELRQF
IVPVEDLDFSINYVDLSSNETTEENLAAYVEKENAIRFDLEKAPLVRASLIKAAEGKFVFFISMHHIIGDGWSSELLVGE
VVSIYNALIQEREVNLPELRIQYKDYAAWLNNEIEKEGYKISEKYWLDQFSGNLPTIELPGSKIRPSVKTYNGDYLGYEF
SDSFSQQLRDFSTEQNVSLFMVLTAGINTLLSKYTGENDIVVGTPVAGREHPDLENQIGLYLNTLALRTKINQKNSFLEL
LQHEKEVILGAYENQLYPFDELIDKLQLKRDRSKALLFDILIVLHNQTKLNMEDDEKLVDLYIKPYASTRKTSQFDLSFR
FSDNERLYLEINYNTDIYEKSFIEKVFTHFEALVFQLITKPEIKLELVDFLSEEDKREIEMSDYWKSVFKNEFSNVVFPF
EKQTLEKLDKSGAQFQFSINEELKEGLEKLSDSNSGDLFTSVLFSLKTTVRKYIENDEVAFHISIPEEAPNEWHKLDLPF
VTNISNDELLLDVYNDLNFRITELKENLFTDFQLAKKTADSFYKQNEAAVFNIKYNYHKNHDFQDWVQLESTEGNEFEKS
IIFKEEAAITHNMSFDFYENESSVTCVLTYNADKYDKNQVVLFIERFKIVMNQIANTKEQFSKLTTREISFNYQKEKQAG
KSKMLLEENF
>Mature_2409_residues
SKKIIHTVFESVVQSQGSNIALQGDQGNISYQELNQYSNKLAHLLLNNNISRNDIATVYFSDPRLQVISLLGALKSGAIY
LPIDKKYKRNHWEELYTTILPKVYITASEDLPLLHQFSDSFDYSIPFIITLLIDSHGALKHKLYAYSNKTYVDVTSKTPL
SDENPNLEFGENDPNYIYFTSGSTGNPKAVLGCHKSLSHFIHWESKELGIKESDKIGLLPSFSFDASIQAVFMALINGST
LCLINSETKEDIIQLQNWIRNYNITVLHMVPTLFRILSIYSEGKDKNLSFPDLKYILLAGEKLYNKDVVNWRECHGNNTE
IINFYGTTEATILSTFYRIEQELQGELSDVFCVGQPISNTAILILNKENKLCKIGEVGSIYIKTPFLTKGYYKNPELTAD
KFIQNPLTASTDIIYKTGDYGKYDSQRNTIVTGREDGLVKINGVRIDINTIEQTILKLKEVDMVKCLTYQQDLLNVILVC
FYKSAAVNENDIRKHCLEYLSQYEMPSRFIALDEVPINANGKIDPVVLKKIIDDTLAADNNETEDETQADETEQKLIQIW
KEILNVEKIRLKDNYLFLGGNSIKLIQLRLRIQQNFDVELSIYDLFTNPVLKEQAKLIAESKKSVFEAIPQVQAQEYYNL
SSTQYRMWVVSQIESSSIAYNMPSAFLLKGEIDKLKFNEAFKNIIERHEILRTFFKSNQDGEVHQYITPVNEAAFEITEK
DLSHFNSLEEIKPYLISLNAEPFNLEEAPLLRAYLIKVNENQHVFYFTMHHIIGDGWSSLILLKEIISTYNSLLNGNQTE
LEGLNIQFKDYVAWSQNETHLEKNKISENYWLDQFSGELPVLELPGFKKRPLIKTNNGNKIEHVYSAEFTKKLKSFSETQ
NVTLFMTLMAGINTLLSRYSGQDDIIVGTPVAGREHPDLENQIGPYLNTVAIRTKLEEQETFTSLLLKEKQLLLNSYQHQ
DYPFDELVWKLNLAQDSSRSFLFDVLVVLQNQNQVANLNISEELSGIKIEPVDFESNFSKFDLNFMFIEAENLNLSITYN
TDIYDQFLIKRMFQHFEILLNQFTANPDVAVNKVDYLTENEKTQLLFDFNDLIVEYPKDKTIVDLFEEQAANNPNVTAIA
FEEKNITYADLSKEVNALAAQLSEQNVERGDKIIICFNSHIEKAITGLLAVLKIGAVYVPVDSDYPLERIRFIVEDTKAK
FVITNSLDAVIFKDVNADIIALDEQKEFENSKELVFEKINISDNAYVIYTSGSTGNPKGVVVSHRNINDYVFGLKSKIQI
QKNDSFALMSTLATDLGNTVLFGSLLTGKTLHLFSKDSLRDVNYIQEYYENHSIDCIKIVPSYWKSLNLKSQSPNKMIIF
GGEELTVDVVEQIKNEKPAITIVNHYGPTETTIGKLLHVVDLENSYDRIPIGRPFSNTNVFVVDQNFLLCPVGVEGELVI
GGDGVSNGYLNNLQLTETQFVKDTLLQTEAKLYKTGDKVKQFPNGDIEYLGRFDDQVKIRGHRIELGEISRNLALIEGIS
QSIVTVGQNNEEKFLIAYYVSETQLDKKEIQSSLSKVLPEYMVPSYYVKLESLPLTSNGKINRKALPKISEKDIIRKEYV
GPRNKTEEKLVQIWQEILKVETIGVTDNFFNLGGHSLLVVRILNLIKKEIGLNISVKTFFENPTIDALSGQLKGKETESF
FIEKIAPADSYPVTASQKKFWLISQFEDASLAYNMLTVFRLEGNLIIPKFQESFIHLIERHESLRTSFKLNEDEELRQFI
VPVEDLDFSINYVDLSSNETTEENLAAYVEKENAIRFDLEKAPLVRASLIKAAEGKFVFFISMHHIIGDGWSSELLVGEV
VSIYNALIQEREVNLPELRIQYKDYAAWLNNEIEKEGYKISEKYWLDQFSGNLPTIELPGSKIRPSVKTYNGDYLGYEFS
DSFSQQLRDFSTEQNVSLFMVLTAGINTLLSKYTGENDIVVGTPVAGREHPDLENQIGLYLNTLALRTKINQKNSFLELL
QHEKEVILGAYENQLYPFDELIDKLQLKRDRSKALLFDILIVLHNQTKLNMEDDEKLVDLYIKPYASTRKTSQFDLSFRF
SDNERLYLEINYNTDIYEKSFIEKVFTHFEALVFQLITKPEIKLELVDFLSEEDKREIEMSDYWKSVFKNEFSNVVFPFE
KQTLEKLDKSGAQFQFSINEELKEGLEKLSDSNSGDLFTSVLFSLKTTVRKYIENDEVAFHISIPEEAPNEWHKLDLPFV
TNISNDELLLDVYNDLNFRITELKENLFTDFQLAKKTADSFYKQNEAAVFNIKYNYHKNHDFQDWVQLESTEGNEFEKSI
IFKEEAAITHNMSFDFYENESSVTCVLTYNADKYDKNQVVLFIERFKIVMNQIANTKEQFSKLTTREISFNYQKEKQAGK
SKMLLEENF

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=429, Percent_Identity=28.2051282051282, Blast_Score=121, Evalue=8e-27,
Organism=Homo sapiens, GI13375727, Length=527, Percent_Identity=22.2011385199241, Blast_Score=86, Evalue=6e-16,
Organism=Homo sapiens, GI122937307, Length=530, Percent_Identity=23.5849056603774, Blast_Score=77, Evalue=2e-13,
Organism=Homo sapiens, GI38505220, Length=378, Percent_Identity=23.5449735449735, Blast_Score=75, Evalue=1e-12,
Organism=Escherichia coli, GI1786801, Length=1096, Percent_Identity=25.456204379562, Blast_Score=306, Evalue=1e-83,
Organism=Escherichia coli, GI1790505, Length=627, Percent_Identity=22.488038277512, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI145693145, Length=543, Percent_Identity=24.4935543278085, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI221142682, Length=499, Percent_Identity=23.4468937875752, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1786810, Length=530, Percent_Identity=21.5094339622642, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=1171, Percent_Identity=22.7156276686593, Blast_Score=199, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17556356, Length=562, Percent_Identity=24.9110320284698, Blast_Score=141, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32563687, Length=534, Percent_Identity=23.5955056179775, Blast_Score=100, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17558820, Length=510, Percent_Identity=24.5098039215686, Blast_Score=92, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32564420, Length=406, Percent_Identity=24.6305418719212, Blast_Score=83, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32564422, Length=406, Percent_Identity=24.6305418719212, Blast_Score=82, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71985884, Length=369, Percent_Identity=24.390243902439, Blast_Score=80, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531443, Length=319, Percent_Identity=24.7648902821317, Blast_Score=75, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538037, Length=434, Percent_Identity=24.1935483870968, Blast_Score=74, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560308, Length=539, Percent_Identity=21.5213358070501, Blast_Score=70, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557194, Length=426, Percent_Identity=23.7089201877934, Blast_Score=69, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=832, Percent_Identity=25, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24648676, Length=627, Percent_Identity=26.1562998405104, Blast_Score=170, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24582852, Length=367, Percent_Identity=28.0653950953678, Blast_Score=87, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19922652, Length=441, Percent_Identity=23.5827664399093, Blast_Score=77, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 276751; Mature: 276620

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIIHTVFESVVQSQGSNIALQGDQGNISYQELNQYSNKLAHLLLNNNISRNDIATVY
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FSDPRLQVISLLGALKSGAIYLPIDKKYKRNHWEELYTTILPKVYITASEDLPLLHQFSD
ECCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHCC
SFDYSIPFIITLLIDSHGALKHKLYAYSNKTYVDVTSKTPLSDENPNLEFGENDPNYIYF
CCCCCHHEEEEEEECCCCCHHEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEE
TSGSTGNPKAVLGCHKSLSHFIHWESKELGIKESDKIGLLPSFSFDASIQAVFMALINGS
ECCCCCCCHHEEHHHHHHHHHEECCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
TLCLINSETKEDIIQLQNWIRNYNITVLHMVPTLFRILSIYSEGKDKNLSFPDLKYILLA
EEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GEKLYNKDVVNWRECHGNNTEIINFYGTTEATILSTFYRIEQELQGELSDVFCVGQPISN
CCHHHCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
TAILILNKENKLCKIGEVGSIYIKTPFLTKGYYKNPELTADKFIQNPLTASTDIIYKTGD
CEEEEEECCCCEEEECCCCEEEEECCCEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCC
YGKYDSQRNTIVTGREDGLVKINGVRIDINTIEQTILKLKEVDMVKCLTYQQDLLNVILV
CCCCCCCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFYKSAAVNENDIRKHCLEYLSQYEMPSRFIALDEVPINANGKIDPVVLKKIIDDTLAAD
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCC
NNETEDETQADETEQKLIQIWKEILNVEKIRLKDNYLFLGGNSIKLIQLRLRIQQNFDVE
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEEEEEEECCCCCCEE
LSIYDLFTNPVLKEQAKLIAESKKSVFEAIPQVQAQEYYNLSSTQYRMWVVSQIESSSIA
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEEEECCCCCEE
YNMPSAFLLKGEIDKLKFNEAFKNIIERHEILRTFFKSNQDGEVHQYITPVNEAAFEITE
EECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHH
KDLSHFNSLEEIKPYLISLNAEPFNLEEAPLLRAYLIKVNENQHVFYFTMHHIIGDGWSS
HHHHHHCCHHHCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEEEEEHHHCCCHHH
LILLKEIISTYNSLLNGNQTELEGLNIQFKDYVAWSQNETHLEKNKISENYWLDQFSGEL
HHHHHHHHHHHHHHHCCCCCEECCCCEEEEEEEEECCCCCHHHHHHCCCCCCHHHHCCCC
PVLELPGFKKRPLIKTNNGNKIEHVYSAEFTKKLKSFSETQNVTLFMTLMAGINTLLSRY
CEEECCCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
SGQDDIIVGTPVAGREHPDLENQIGPYLNTVAIRTKLEEQETFTSLLLKEKQLLLNSYQH
CCCCCEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDYPFDELVWKLNLAQDSSRSFLFDVLVVLQNQNQVANLNISEELSGIKIEPVDFESNFS
CCCCHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCHHHHCCCCEEEEECCCCCCC
KFDLNFMFIEAENLNLSITYNTDIYDQFLIKRMFQHFEILLNQFTANPDVAVNKVDYLTE
EEEEEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHCCCC
NEKTQLLFDFNDLIVEYPKDKTIVDLFEEQAANNPNVTAIAFEEKNITYADLSKEVNALA
CCCEEEEEEECHHHEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
AQLSEQNVERGDKIIICFNSHIEKAITGLLAVLKIGAVYVPVDSDYPLERIRFIVEDTKA
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHCCCCE
KFVITNSLDAVIFKDVNADIIALDEQKEFENSKELVFEKINISDNAYVIYTSGSTGNPKG
EEEEECCCCEEEEEECCCCEEEECCHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCE
VVVSHRNINDYVFGLKSKIQIQKNDSFALMSTLATDLGNTVLFGSLLTGKTLHLFSKDSL
EEEECCCCCHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEHHHCCCEEEEECCCCC
RDVNYIQEYYENHSIDCIKIVPSYWKSLNLKSQSPNKMIIFGGEELTVDVVEQIKNEKPA
HHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCCCCCEEEEECCCEEEHHHHHHHCCCCCE
ITIVNHYGPTETTIGKLLHVVDLENSYDRIPIGRPFSNTNVFVVDQNFLLCPVGVEGELV
EEEEECCCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCEEE
IGGDGVSNGYLNNLQLTETQFVKDTLLQTEAKLYKTGDKVKQFPNGDIEYLGRFDDQVKI
ECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCCCCEEEE
RGHRIELGEISRNLALIEGISQSIVTVGQNNEEKFLIAYYVSETQLDKKEIQSSLSKVLP
EEEEEEHHHHHCHHHHHHHCCHHEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
EYMVPSYYVKLESLPLTSNGKINRKALPKISEKDIIRKEYVGPRNKTEEKLVQIWQEILK
HHCCCCEEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VETIGVTDNFFNLGGHSLLVVRILNLIKKEIGLNISVKTFFENPTIDALSGQLKGKETES
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCCHH
FFIEKIAPADSYPVTASQKKFWLISQFEDASLAYNMLTVFRLEGNLIIPKFQESFIHLIE
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHEEEEEEEECCCEECCHHHHHHHHHHH
RHESLRTSFKLNEDEELRQFIVPVEDLDFSINYVDLSSNETTEENLAAYVEKENAIRFDL
HHHHHHHHCCCCCHHHHHHHHCCHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEC
EKAPLVRASLIKAAEGKFVFFISMHHIIGDGWSSELLVGEVVSIYNALIQEREVNLPELR
CCCCHHHHHHHHHCCCCEEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
IQYKDYAAWLNNEIEKEGYKISEKYWLDQFSGNLPTIELPGSKIRPSVKTYNGDYLGYEF
EEHHHHHHHHCCHHHHCCCEEHHHHHHHHHCCCCCEEECCCCCCCCCCEECCCCEECEEC
SDSFSQQLRDFSTEQNVSLFMVLTAGINTLLSKYTGENDIVVGTPVAGREHPDLENQIGL
CHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHH
YLNTLALRTKINQKNSFLELLQHEKEVILGAYENQLYPFDELIDKLQLKRDRSKALLFDI
HHHHHHHHHHCCCCHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHH
LIVLHNQTKLNMEDDEKLVDLYIKPYASTRKTSQFDLSFRFSDNERLYLEINYNTDIYEK
HHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHH
SFIEKVFTHFEALVFQLITKPEIKLELVDFLSEEDKREIEMSDYWKSVFKNEFSNVVFPF
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECC
EKQTLEKLDKSGAQFQFSINEELKEGLEKLSDSNSGDLFTSVLFSLKTTVRKYIENDEVA
HHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
FHISIPEEAPNEWHKLDLPFVTNISNDELLLDVYNDLNFRITELKENLFTDFQLAKKTAD
EEEECCCCCCCCCEEECCCEEECCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHH
SFYKQNEAAVFNIKYNYHKNHDFQDWVQLESTEGNEFEKSIIFKEEAAITHNMSFDFYEN
HHHHCCCCEEEEEEEECCCCCCHHHHHEEECCCCCCHHHHEEEECCCCEEECCEEEEEEC
ESSVTCVLTYNADKYDKNQVVLFIERFKIVMNQIANTKEQFSKLTTREISFNYQKEKQAG
CCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHEECCCHHHHHCC
KSKMLLEENF
CCCCEEECCC
>Mature Secondary Structure 
SKKIIHTVFESVVQSQGSNIALQGDQGNISYQELNQYSNKLAHLLLNNNISRNDIATVY
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
FSDPRLQVISLLGALKSGAIYLPIDKKYKRNHWEELYTTILPKVYITASEDLPLLHQFSD
ECCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHCC
SFDYSIPFIITLLIDSHGALKHKLYAYSNKTYVDVTSKTPLSDENPNLEFGENDPNYIYF
CCCCCHHEEEEEEECCCCCHHEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEE
TSGSTGNPKAVLGCHKSLSHFIHWESKELGIKESDKIGLLPSFSFDASIQAVFMALINGS
ECCCCCCCHHEEHHHHHHHHHEECCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
TLCLINSETKEDIIQLQNWIRNYNITVLHMVPTLFRILSIYSEGKDKNLSFPDLKYILLA
EEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GEKLYNKDVVNWRECHGNNTEIINFYGTTEATILSTFYRIEQELQGELSDVFCVGQPISN
CCHHHCCCCCCHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
TAILILNKENKLCKIGEVGSIYIKTPFLTKGYYKNPELTADKFIQNPLTASTDIIYKTGD
CEEEEEECCCCEEEECCCCEEEEECCCEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCC
YGKYDSQRNTIVTGREDGLVKINGVRIDINTIEQTILKLKEVDMVKCLTYQQDLLNVILV
CCCCCCCCCEEEECCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFYKSAAVNENDIRKHCLEYLSQYEMPSRFIALDEVPINANGKIDPVVLKKIIDDTLAAD
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCC
NNETEDETQADETEQKLIQIWKEILNVEKIRLKDNYLFLGGNSIKLIQLRLRIQQNFDVE
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEEEEEEECCCCCCEE
LSIYDLFTNPVLKEQAKLIAESKKSVFEAIPQVQAQEYYNLSSTQYRMWVVSQIESSSIA
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEEEECCCCCEE
YNMPSAFLLKGEIDKLKFNEAFKNIIERHEILRTFFKSNQDGEVHQYITPVNEAAFEITE
EECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHH
KDLSHFNSLEEIKPYLISLNAEPFNLEEAPLLRAYLIKVNENQHVFYFTMHHIIGDGWSS
HHHHHHCCHHHCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEEEEEHHHCCCHHH
LILLKEIISTYNSLLNGNQTELEGLNIQFKDYVAWSQNETHLEKNKISENYWLDQFSGEL
HHHHHHHHHHHHHHHCCCCCEECCCCEEEEEEEEECCCCCHHHHHHCCCCCCHHHHCCCC
PVLELPGFKKRPLIKTNNGNKIEHVYSAEFTKKLKSFSETQNVTLFMTLMAGINTLLSRY
CEEECCCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
SGQDDIIVGTPVAGREHPDLENQIGPYLNTVAIRTKLEEQETFTSLLLKEKQLLLNSYQH
CCCCCEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QDYPFDELVWKLNLAQDSSRSFLFDVLVVLQNQNQVANLNISEELSGIKIEPVDFESNFS
CCCCHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCEEECCHHHHCCCCEEEEECCCCCCC
KFDLNFMFIEAENLNLSITYNTDIYDQFLIKRMFQHFEILLNQFTANPDVAVNKVDYLTE
EEEEEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHCCCC
NEKTQLLFDFNDLIVEYPKDKTIVDLFEEQAANNPNVTAIAFEEKNITYADLSKEVNALA
CCCEEEEEEECHHHEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
AQLSEQNVERGDKIIICFNSHIEKAITGLLAVLKIGAVYVPVDSDYPLERIRFIVEDTKA
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHCCCCE
KFVITNSLDAVIFKDVNADIIALDEQKEFENSKELVFEKINISDNAYVIYTSGSTGNPKG
EEEEECCCCEEEEEECCCCEEEECCHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCE
VVVSHRNINDYVFGLKSKIQIQKNDSFALMSTLATDLGNTVLFGSLLTGKTLHLFSKDSL
EEEECCCCCHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEHHHCCCEEEEECCCCC
RDVNYIQEYYENHSIDCIKIVPSYWKSLNLKSQSPNKMIIFGGEELTVDVVEQIKNEKPA
HHHHHHHHHHHCCCCEEEEECHHHHHCCCCCCCCCCEEEEECCCEEEHHHHHHHCCCCCE
ITIVNHYGPTETTIGKLLHVVDLENSYDRIPIGRPFSNTNVFVVDQNFLLCPVGVEGELV
EEEEECCCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCEEE
IGGDGVSNGYLNNLQLTETQFVKDTLLQTEAKLYKTGDKVKQFPNGDIEYLGRFDDQVKI
ECCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHCCCCCEEEE
RGHRIELGEISRNLALIEGISQSIVTVGQNNEEKFLIAYYVSETQLDKKEIQSSLSKVLP
EEEEEEHHHHHCHHHHHHHCCHHEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
EYMVPSYYVKLESLPLTSNGKINRKALPKISEKDIIRKEYVGPRNKTEEKLVQIWQEILK
HHCCCCEEEEEECCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
VETIGVTDNFFNLGGHSLLVVRILNLIKKEIGLNISVKTFFENPTIDALSGQLKGKETES
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCCHH
FFIEKIAPADSYPVTASQKKFWLISQFEDASLAYNMLTVFRLEGNLIIPKFQESFIHLIE
HHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHEEEEEEEECCCEECCHHHHHHHHHHH
RHESLRTSFKLNEDEELRQFIVPVEDLDFSINYVDLSSNETTEENLAAYVEKENAIRFDL
HHHHHHHHCCCCCHHHHHHHHCCHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEC
EKAPLVRASLIKAAEGKFVFFISMHHIIGDGWSSELLVGEVVSIYNALIQEREVNLPELR
CCCCHHHHHHHHHCCCCEEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
IQYKDYAAWLNNEIEKEGYKISEKYWLDQFSGNLPTIELPGSKIRPSVKTYNGDYLGYEF
EEHHHHHHHHCCHHHHCCCEEHHHHHHHHHCCCCCEEECCCCCCCCCCEECCCCEECEEC
SDSFSQQLRDFSTEQNVSLFMVLTAGINTLLSKYTGENDIVVGTPVAGREHPDLENQIGL
CHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHH
YLNTLALRTKINQKNSFLELLQHEKEVILGAYENQLYPFDELIDKLQLKRDRSKALLFDI
HHHHHHHHHHCCCCHHHHHHHHCCHHEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHH
LIVLHNQTKLNMEDDEKLVDLYIKPYASTRKTSQFDLSFRFSDNERLYLEINYNTDIYEK
HHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHH
SFIEKVFTHFEALVFQLITKPEIKLELVDFLSEEDKREIEMSDYWKSVFKNEFSNVVFPF
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEECC
EKQTLEKLDKSGAQFQFSINEELKEGLEKLSDSNSGDLFTSVLFSLKTTVRKYIENDEVA
HHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
FHISIPEEAPNEWHKLDLPFVTNISNDELLLDVYNDLNFRITELKENLFTDFQLAKKTAD
EEEECCCCCCCCCEEECCCEEECCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHH
SFYKQNEAAVFNIKYNYHKNHDFQDWVQLESTEGNEFEKSIIFKEEAAITHNMSFDFYEN
HHHHCCCCEEEEEEEECCCCCCHHHHHEEECCCCCCHHHHEEEECCCCEEECCEEEEEEC
ESSVTCVLTYNADKYDKNQVVLFIERFKIVMNQIANTKEQFSKLTTREISFNYQKEKQAG
CCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHHHEECCCHHHHHCC
KSKMLLEENF
CCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]