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The map label for this gene is ydfG [C]

Identifier: 146299849

GI number: 146299849

Start: 2496656

End: 2497432

Strand: Direct

Name: ydfG [C]

Synonym: Fjoh_2091

Alternate gene names: 146299849

Gene position: 2496656-2497432 (Clockwise)

Preceding gene: 146299848

Following gene: 146299850

Centisome position: 40.95

GC content: 38.61

Gene sequence:

>777_bases
ATGAAAAACACAAATAGAGTAGGAATAATAACCGGCGCAAGTTCAGGCATAGGCAGGAATACTGCATTACGTATCGCTTC
TGATGGTTTTAGAATTGTTTTAAACGGACGAAACGAAAAAGAATTGGATTTATTAAAACAAGAAATAAATACAAAAACCG
GAACAGAAACAGCCATTGTTATTGCTGGTGATGTTACAGATAAAGAAACCCTCGAAAAATGTATTAAGGCTTGTTACGAA
AATTGGAATGTAAGTCCAACCCTTTTTGTAGCCTGTGCCGGAAGAGGGCTGCCGGGAACATTAATTACTTCAGATGAAAT
GCAATGGGAAAATCTATGGCATATAAACGTTCTTGGCTTGCAGCATCAGTTAAAAGCAATTTCTCAGGTTATGATAGCCG
AAAGAGAAAAAGGCTCAGATACCGAAACTCCTTCAGATATTGTAGTAATAGGTTCAACGATAGGAAGAAATGTTTCTCCA
TTTAACTCTGTTTACGGAGCTACAAAATTTGCAACTCATGGTTTAACAGAAGCCCTGCGAAGAGAATTAGGACCTAAAGG
AATCAGAGTTACGTTGATTGAGCCAGGTTTGGTTTCGACAAATTTTCAGGAATCTGCAGGTTATGATATGGATTGGTTCG
AAAATTACTGTAACGAAATCGGGCCGGTGCTTGTAGGCGATGATGTAGCAAAAGTTGTTCAGTTTTTGGTTCAAATGCCC
GGAAATGTGCATTTAGATAATATTTCGATCAGGCCGACAAGACAGTCCTACCCATAA

Upstream 100 bases:

>100_bases
AGCCAGGAGGAACTTTTGGAACAGGAAGATTTCTTCAGTGCAATTATTTCTGAAATCAGCGAAGAGTTTTAAAACATTTA
CTAAAGAAAAAAATAATAAA

Downstream 100 bases:

>100_bases
TTCAATTTAATTATTCATTTGACATTTTTTGAGATGATACAAGAGCAAAAAAAATTAACCGATTTATTTGAGCATATCTC
AAATAATTATCCTGATCGCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKNTNRVGIITGASSGIGRNTALRIASDGFRIVLNGRNEKELDLLKQEINTKTGTETAIVIAGDVTDKETLEKCIKACYE
NWNVSPTLFVACAGRGLPGTLITSDEMQWENLWHINVLGLQHQLKAISQVMIAEREKGSDTETPSDIVVIGSTIGRNVSP
FNSVYGATKFATHGLTEALRRELGPKGIRVTLIEPGLVSTNFQESAGYDMDWFENYCNEIGPVLVGDDVAKVVQFLVQMP
GNVHLDNISIRPTRQSYP

Sequences:

>Translated_258_residues
MKNTNRVGIITGASSGIGRNTALRIASDGFRIVLNGRNEKELDLLKQEINTKTGTETAIVIAGDVTDKETLEKCIKACYE
NWNVSPTLFVACAGRGLPGTLITSDEMQWENLWHINVLGLQHQLKAISQVMIAEREKGSDTETPSDIVVIGSTIGRNVSP
FNSVYGATKFATHGLTEALRRELGPKGIRVTLIEPGLVSTNFQESAGYDMDWFENYCNEIGPVLVGDDVAKVVQFLVQMP
GNVHLDNISIRPTRQSYP
>Mature_258_residues
MKNTNRVGIITGASSGIGRNTALRIASDGFRIVLNGRNEKELDLLKQEINTKTGTETAIVIAGDVTDKETLEKCIKACYE
NWNVSPTLFVACAGRGLPGTLITSDEMQWENLWHINVLGLQHQLKAISQVMIAEREKGSDTETPSDIVVIGSTIGRNVSP
FNSVYGATKFATHGLTEALRRELGPKGIRVTLIEPGLVSTNFQESAGYDMDWFENYCNEIGPVLVGDDVAKVVQFLVQMP
GNVHLDNISIRPTRQSYP

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=256, Percent_Identity=28.90625, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=26.7782426778243, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=209, Percent_Identity=30.622009569378, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI7657478, Length=206, Percent_Identity=30.5825242718447, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=205, Percent_Identity=28.2926829268293, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=32.4607329842932, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI32483357, Length=238, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI223718074, Length=208, Percent_Identity=34.1346153846154, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=243, Percent_Identity=28.3950617283951, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787820, Length=253, Percent_Identity=28.4584980237154, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786701, Length=199, Percent_Identity=27.1356783919598, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=205, Percent_Identity=29.2682926829268, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082100, Length=205, Percent_Identity=30.7317073170732, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=249, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=248, Percent_Identity=29.0322580645161, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=26.3358778625954, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=210, Percent_Identity=29.5238095238095, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=245, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=249, Percent_Identity=25.7028112449799, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=240, Percent_Identity=24.5833333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=204, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=249, Percent_Identity=24.8995983935743, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=244, Percent_Identity=27.0491803278689, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=243, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=245, Percent_Identity=24.8979591836735, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=259, Percent_Identity=31.2741312741313, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639444, Length=195, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24584752, Length=192, Percent_Identity=30.7291666666667, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648944, Length=257, Percent_Identity=27.6264591439689, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=216, Percent_Identity=27.3148148148148, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=212, Percent_Identity=29.2452830188679, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007236, Length=265, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355319, Length=239, Percent_Identity=25.5230125523013, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357041, Length=212, Percent_Identity=26.4150943396226, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28263; Mature: 28263

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTNRVGIITGASSGIGRNTALRIASDGFRIVLNGRNEKELDLLKQEINTKTGTETAIV
CCCCCEEEEEECCCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEE
IAGDVTDKETLEKCIKACYENWNVSPTLFVACAGRGLPGTLITSDEMQWENLWHINVLGL
EEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEECCCCCCCCEEEEEEECH
QHQLKAISQVMIAEREKGSDTETPSDIVVIGSTIGRNVSPFNSVYGATKFATHGLTEALR
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RELGPKGIRVTLIEPGLVSTNFQESAGYDMDWFENYCNEIGPVLVGDDVAKVVQFLVQMP
HHCCCCCEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHCC
GNVHLDNISIRPTRQSYP
CCEEECCEEECCCCCCCC
>Mature Secondary Structure
MKNTNRVGIITGASSGIGRNTALRIASDGFRIVLNGRNEKELDLLKQEINTKTGTETAIV
CCCCCEEEEEECCCCCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEE
IAGDVTDKETLEKCIKACYENWNVSPTLFVACAGRGLPGTLITSDEMQWENLWHINVLGL
EEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEECCCCCCCCEEEEEEECH
QHQLKAISQVMIAEREKGSDTETPSDIVVIGSTIGRNVSPFNSVYGATKFATHGLTEALR
HHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RELGPKGIRVTLIEPGLVSTNFQESAGYDMDWFENYCNEIGPVLVGDDVAKVVQFLVQMP
HHCCCCCEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHCCEEECHHHHHHHHHHHHCC
GNVHLDNISIRPTRQSYP
CCEEECCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]