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The map label for this gene is tycC [H]

Identifier: 146299846

GI number: 146299846

Start: 2476740

End: 2485424

Strand: Direct

Name: tycC [H]

Synonym: Fjoh_2088

Alternate gene names: 146299846

Gene position: 2476740-2485424 (Clockwise)

Preceding gene: 146299845

Following gene: 146299847

Centisome position: 40.62

GC content: 32.9

Gene sequence:

>8685_bases
ATGAACCACATCAATGACAAAATAGCAAAAGATTACTGGTACAAAAAAAACAATAGAATTGTGTATACAAAAGAAGGTTT
TTCTGAAAACACTTCTGTTGATTTTACCATTGTCGATGCCGGCAGACTCTCTTATTTCTATAAAGTAACAGGAGAAAATA
CAGATGCAGAATTTACAGTTTTAATTGCACTTTATAATTTACTGCTGCAAAGATATATTGTCGATGGGAATGTATCGTTT
TTGAAGTCCTTTTTAGATTCTCAAATAGGATTGTTGAGTTATGAGTTTCAGCCAATTGGTAAAAAAACGGTAAAAGAATT
TATACAAGAAACCAAGCAGGAAATTCAGGAAGTGTACAAACATGCTCCTTATTATAAAACTGAGAAAGAAAAAGCGAATG
TCGAATATATTCCTTTTCAGTTTAATTACGGAACAGAAAATAAACTGAATGAATCGTTTAGTGAATTGTCATGTCGCATT
GAAAAGCTTGAGAATAGAGATTTAAAAATCACTTTACATTATTCTTCAAAATTTGCCGAAAATAATCTAGCACTGCATCT
TTTAAAGAATTTTGGAAGATTGCTGGAAGAATTAGAAGCAAATATCAATCTTTCGGCCGTGAAGATTTCTTTGGTATCTA
ATGAAGAAGAAAAAAACTTACTTTATAATCTAAACTCTCAAAAAACAGATTATAATCGTGCTTTAACTCTCGTAGAAATT
GTAGAAAATCAGGTATATAAAACACCTAATGATATTGCAGTTATCTGTAAAGAGAAATCCCTTACTTATGGTGAATTAAA
TAAACTTGCCAACCAGCTTTCTAACTATCTGATACAACAAGGAGTATCTGAAGGTGATTTTGTTGGAGTTAAATTGGAAA
GAAGCGAAAAATTGCTTGTGTCTATATTAGCAGTTTTAAAAGCTGGGGCGACTTATGTACCTCTGGATGTTAATTATCCT
GCAGAAAGAATCGCATACATTGAAACTGACAGCAATTGCAAATTGGTTATTACGGGTGCTGTATACGATGATTTTCTGGA
AAGCCAGGAAAAATATAATATAGAAAATATCTCATTGAACAGAAAATCAGATGATACGGCATATATTATTTATACTTCAG
GAACTACAGGAAATCCAAAAGGTGTAATGATAACGCATCAAAATGCTGTTGCTTTAATTCATTGGGCACAAGAAGAATTT
AATCCGGAAAATTTTGAAATTGTATACGCAGCTACATCACATTGTTTTGATCTTTCGATATACGAAATGTTTTACCCATT
ATCTGTTGGAAAAAGAATCAAAATATTAAATAACGCCCTGGAGATTGGACCAGAATTGACAAAAGATAAAAACATCTTAT
TGAATACAGTTCCGTCAAGTATCCGAAATATTTTAGCTGAAGGATTTTCTCTTGAAAATGTAAGCATTATTAATCTTGCC
GGAGAACCGTTTCCGGTTGATATAGCCAAAAAGTTATTGCAGACCAATGCCGAAATTAGAAATCTGTACGGCCCGTCTGA
AGATACAACTTACAGTACCTGCTATAAATTATCTTCAGCAAAAAACTATCAGACTATACCAATTGGTAAAGCCATTTCGA
ATACTCAGGCTTATATTTTAGATGAAGAACTGCAATTAGTGCCTATGGGTACAATTGGAAAATTATACCTTTCAGGAGAT
GGAATTGCAAATGGTTATCTCAATAAACCAGAATTGACTGCAGCAAAGTTTATAGAAAACCCTTTTGCTGAAGGGCACAA
AATGTATGATACAGGCGATTTAGTAAAATGGATGCCTGATGGAAATCTGGCTTTTCTTGGCAGAAAAGACCATCAGATAA
AACTTCGCGGTTATCGTATTGAACTTGAAGAAATAGAAAATGTAATTTCTTCCTTTTCTGAAAATATTGGACAGGCAGTT
GTTGCAGTAAGAAAAAATAATGGTGAAGATTTTTTAGCTGCCTATTTTACAGAAATTGAAAATGTAAGTAAAACAGATTT
AAGAGCTTATTTAGAAAAGCAGCTTCCGGCTTACATGATTCCATCTTATTTTACAGCGGTAGAAAAAATTCCATTAACTC
CAAACGGCAAGATAAACAAAGATGCCCTTTCTGAAATTACGGATGCTTTCATTGTTAAAAACGAGTATGAAGCTCCTTCG
GATGCTGTTGAAAACGAATTAGTTGAGATTTGGGAGCAGACTCTCGGAATTTCTCCAATTGGTGTAAATGATCATTTTTT
TGAATTGGGAGGTCATAGTTTAATGATTTCTCAGATTATAAATGCGATTTACAAGAACCTTAATAAAAGCGTTCCATACA
AAGTTTTTTATACCAATCCTACAATCAAAGATTTAAGAAAGTCATTGAAGGATCAGGAATATTTACCAATCCCTTTAACA
CCTTATTCTGAATCGTACCCATTAACACATTCCCAAAACAGGTTATGGATGTTAAGCCAATTAGAAGGCGGAAACGAAGC
CTATCAAATATCCGGAGCTGTAGTTTTGAAAGGACAATTAAATGCTTATAATTTTTGTAATGCATTCGATCATGTAATTA
CGCATCACGAAGTTCTTAGAACGATTTTTAAGAAAAATGAAGAAGGAACTGTAAAACAATATATTATTCCTGATAATGAA
TTTCATTTTGCAATAGAAAATAAAGATTTTTCTACTTCTACATCTCCGTATGAAGAGATACAAAGTTATATAGGAGAAAA
AAATAAAGAAAGTTATAATCTGGCAGAAGCACCTTTATTTAAAGCCTCTTTATTAAAGACTGCTGCTGATAATTTTGTGT
TCTATTTGTCGATTCACCACCTTATAAGCGATGGATGGTCATTAAAAGTCCTAACTGCACAAGTTTTAGAATATTATACC
ATTTTAGAATCTGGAAATGTTATTCCATCTCCTGAACATAAAATTCAGTTTAAGGATTATGCTGCCTGGACGCAGGATGA
ACAAAATAAGAAAAACTACCAGCTGGCACAAGAATATTGGTTAAAGCAGTTTGAAGAAACTGTGCCTGTACTTCAGTTAC
CGGGATATAACGGTCGTCCTGCTGTAAAAACCTATGCAGGAAACCAATACCGTCATACATTTTCGAAAGAATTGTTTACT
GAATTAAAAAATCTTTCTAAAGGGTATCAGGTAACTTTATTTACAGCATTAATGGCAGGTGTAAAAACTTTATTATCAAG
ATATGCCAGCCAGAATGATATTGTTATTGGAACTCCAATAGCCGGAAGGGAGCATCCGGATTTAGAACATCAAATAGGTT
TATATATCAATACACTTGCTGTAAGAACTTTATTGAACCCAAAAGAAACATTTTCTGCATTACTTCAAAGAGAAGGTAAA
CAGCTTTTAGAAGCCTATGAACATCAGAATTATCCTTTTGATGCTTTGGTAGAACAATTAAAACTATCGAGAGATACCTC
AAGATCTCCTTTGTTCGATATTATGGTCGTTTTGCAAAATCAGCATCAGGTATCTAATTTTATAGATAAAAAATCTTCAG
AGATAACTATCGAAGATTTTGAAATTAGCAGTGAAGTTTCTGCTTTTGATATCGTCTTTACTTTTACAGAAAAAGAAACA
CTGGAACTTGAAATTCTCTATAATACAGATATTTATACTGCTGAATATATTGAGAGACTATCTGCGCATTTAGAAAATCT
GCTGCAGCAAGTTGTTAAAAAACCTCAAGTGCTTTTAGAAGAAATAGAATTAGTATCTGAAGACGAAAAAGTAATCTTAC
TGAATGAATTTAACGATACAGATTTTGTTTTTGATACAGATAAAACTGTTATTGATCATTTCTTACAGCAAGTTCGAAAA
ACACCTCAAAAAACAGCTGTTATTGTTGATGATCAAACTTTGACCTATGCTGAATTGGATGAAATGTCTAATAAACTGGC
CAATTATCTTATTGAAAATTATCAGCTTGGAAAAGGAAATTTTGCAGCAGTTAAGCTGGAAAGAGGTTTATATTTGATCA
TATCTTTATTAGGAATTTTAAAAACTGGTGCTGCTTATGTTCCTGTTGACATAAACTATCCGGAAAACAGGATAAAAGAT
ATTCTTGACGACGTTTCCCCAAAAGCAATAATAGACGACGCATTTTGGAATGATTTTGATTCTAATGAAAGCTCTGCTTT
ACAGCCTAAAACACTGCCAAAAGGCACAGACCTGGCTTATGTAATTTACACTTCTGGATCTACAGGAAAACCAAAAGGAG
TGATGATTGCACATCAGAGTTTGGTAAACTTATGTTTTTGGCATAAAAAGGCATATAATGTCGATGAAAACAGCAGAGGT
ACTTTATTTTCTGGAGTTGCATTCGATGCTTCTGTTTGGGAAATATATCCTTATCTAATATCAGGTGCGGTTTTATATCC
AATTCAAAAAGACGAAATACGTCTTCAAATACCTGAATTAGTTTCGTTTTTGGTAAAAAACGAAATAACGCACAGTTACC
TTCCTTCAAAAATCTGTCAGGATCTAATGGCTGAAACTAATTTGAAACTGCCAGCTTTAATTCTTACCGGAGGTGAACGT
TTAAATTATGCAGTAGATACTTCTCTACAGGTATTTAATAATTATGGACCAACAGAAAATACTGTTGTAACAACTTATTA
TGATTGTAAAAAAGCTCTGAATGAAAAGGTATCTATAGGAAAACCTGTTGCCAATACACAGGTTTATATTTTATCTGAAA
ATTTAAAATTACAGCCAGTTGGTGTAATTGGAGAATTGTGTATTTCTGGAATTGGACTTTCAAAAGGATATTTGAACCAG
CCGGAATTAACCAAAGAAAAGTTCATTCAAAATCCATTTGAACCTGAAGAAAAATTATATAAAACAGGAGATTTAGCCAG
ATGGCTTCCAGACGGAAATCTTGAATATGTAGGAAGAAAAGACAACCAGGTTAAAATTAGAGGAAACAGAGTTGAATTAG
GAGAAATTGAATATGTTATCAGAGAGTTTGATTCAGCGATTTCCAATGCTGTGGTTTTGGTAAAAGAAGTAAAGAATGAA
CCGTTTATAATTGCTTATTACACTACAGGAAAATCTGTTGATAAAAAAGAACTTAGAAAATATTTAAAAGATAAGCTGGC
TGATTATATGATTCCTGCTTATTATGTAGAACTTGAAACGCTGCAGCTGAATGCAAATGGAAAAGTAGATCTTTCTAAAC
TGCCTGCCATATCAGAATCAGATATTGTTAAGAAAGAATATATAGCACCTGCCAATCAAACAGAAGAAAAAATTGCCGTA
ATCTGGCAGGAACTTTTAGGACATCAAAAAATTGGTGCTGGAGATGATTTCTTTGAACTTGGAGGGCACAGTTTATTATT
AACTAAGTTATTAAACGAATACCAGAGAGTATTTAAAATTGCAGTCAATCTAAAAACTCTTTATACAAATTCAAGTCTTA
AAAGCCATGCAGCGCTTTTGATAAATTCAAAAGAAGAAATCGCTGTTATTGAAAAATTATCGTATCAGGAATTTTATGAT
TTATCTCCTTCGCAGGTTAGATATTGGTTATTGTATAAAATAAACGGAAAATCAAAAGAGTTTAATATCTACAGTACGTT
CAATCTACCGGAAAATCTAAATACGGCTGTTTTTGAACAGGCATTTAATATTCTTTTAGAACGACACGAAATTTTAAGAA
GCTTATTTGCTGAAGAAGCCGGAATGCCAAAACAAAAAATAATACAAAATCTGGCGGTGCGAATTCCTGTTTTTGAGTCA
GAAACAGAGATTAAACTGCATGTATTCGAGTACGAATTTGATCTTGAATTAGATTTATTGTTTAGAGCAGCGGTCTTAAA
AAAAGGTGCAGGTTACAGTTTATATTTTAATATGCATCATAGTATTGGCGACGGCTGGTCTATGGGAATTATTTCCAGAG
ATTTAATGGAAATATATAACGCTTTACTAGAAGGAAGAATAGCTCAGCTTCCGGAACTAACCATACAATACAAGGATTAT
GCACAATGGCAGAATAATGTATTGCAGTCACAAGAAATCAAAATCCAGGAAAATTATTGGAAAGAACAATTTGCAGGAAC
GCTGCCGTATCTGCAATTACCATCAGATTATATTTCAAAGCTGAAAAAAGCAGAAACATCATCTTCATACACCCTATTTA
TTTCTGATGAAAAGAAGAAGAAAATAGAAGAGTTATCAAGAAAAAACGGTGCCAGTGTATTCGCAGTATTTGCTGCCGTT
TTAAAAGTGTTATTGTACCGTTTAACTTCAGAAGAAGATATCATTCTTGGAATCCCAACAGCAAACAGAAATCATTATCA
ATTAAAGAATCTGGCAGGGTGTTTTATCAATACACTTATGCTTCGTGATACAATAAACAGTAATTTTTCTTTTGAAACCT
GGCTGGCAAAAGTCAACGAAACTTTGATTAACGCTCTAACACATCAAAATTATCCTTTCGAAAAGGTCTTGGAATTAATT
GATATTCCTCAGGATGATAATCGTTTTCCGTTAAGTCCCGTTTTCTTAAACATGGTCGATTTTGATGCTGGATCACTGGA
TACTATTACAGCATTCACATCAACTCATGAAGTACTAAATACTGCTCCTAAATTTGATTTTGAATGTTATATAAAAAGTT
TCGAAAATGGTTACAGTATTAACTGTGTGTACGATCATGAACTGTTTAAAAAAGAAACTATTCAATATTGGATAAATGCC
TATTTGTCTATTATAGATCAGGTTATAGAAAATGATAAAAAAGCATTGTTTGAAATTAAAATTTTTGAAGACTTTATTTA
TCAGGAAAACGATCTCAAACCGGTTAATGATTTTGGATTTTTTGAAGCAAGCGAAATACAGCAGAGTATAGCACAACGAT
TTGAAAAACAAGTAGAATTGTTTCCAGACCGCGAAGCCGTTGCATCAAAAAATACCGTGCTTACCTATAAAAAACTTAAT
AATTGCGCGAATCATTTAGCACAACAAATAATAGAAAAAGCCAGCACAGAAACTAAACGAGTTGCATTGCTTTTAAATCA
CAACGAAACCTCTGTAATAGGAATGCTTGGAGTGCTTAAAGCAGGCTATGCTTATGTTCCTATAGATGCAAATAGTCCGT
TGAGCAGAATTCAGTATATTATTGAAGATTCTGGATGTGATCAATTAGTTTGTAATGAAGTTACTGTAGAAAAAGCAAAT
CAGTTAAAGAAAGAATTACCGCAATTGTCAATTACAAAGCTTTCTGAAAATTACAATCTTCCAGAAATCTTAAATCCAAA
ACAGAGTTCAAGCCCTTTAGCAGAAGCGTATGTTTTGTATACATCAGGATCAACAGGTATGCCAAAAGGAGTTTTACAGA
TCCAGAAAAATGTTCTTCACTTTATTCGTGTATATACAAACAATGTTCATATCGCGATACAGGATAATTTAAGCGTTTTT
TCGACTTATACTTTCGATGCTTCTGTAAAAGATATTTATGGAGCGATTTTAAACGGAGCCAAAGTAAGTATTTATGATAT
TGTTGAAAACGGACTAGATTCACTTTCTGAATGGCTTTTGGCAGAAAATATTACCATTATACACATGGTGCCAACGATTT
ACAGGAATTTTTTAAAAGGACTGAAAAAAGATGAAGCCGTGCCAACAGTACGATTAGTCGATTTAGGAGGAGAATCATGC
CATAAATCAGATTTGGAATTGTTTAAAGAACATTTCCTTGAAGGTGCATTTTTGGTTAATGATTATGGTCCAACAGAATC
TACTATTGTGGCTCAAAAATTCTTGTCGCATGAATCTGAATTGACAAGAAATAATATGCCATTAGGTAAATCTGTAGAAG
AAACAAAGGTTTTCTTATTAGATGAAAATAATAAACCAAAAGGTATTTATCAAACAGGGGAAATTGTTTTCAAAAGCGAT
TATCTGTCTCTAGGATATCTAAACCGACAGGAATTAACAGATAAGGTTTTTACAACAGATCCTTTAACCGGAAACGGCAG
AGTTTATAAATCCGGCGATATAGGAATGATGCTTCCTTCGGGAGAAATTGAATTCTTACAACGAAAAGATTCTCAGGTAA
AAATCAACGGATTGCGAATTGAATTATCTGAAATAGAATATCAATTAGAGCAGATTGAGTTTATAAATGAAGCAGTGGTT
TTGTTGAAAGAATTACAAGAAAACAGTTATATAACAGCTTATGTTCGATCTGAAGAAATTCTGGATGTGACCAAAATAAA
ATTGCTTTTAGGTAAAATATTACCCAAATATATGATTCCGGCAATCTACATTTCAATGGAAAATTTCCCATTGACACGAA
CTGGAAAAATAGAAAGAAAAGCTTTGCCAGATCCCGTAATTTCTGATTTAAAAACGGTTCCTTATGAAGCTCCGGCAAAC
GATGTTGAAAGCAGACTAGTACACATTTGGGCAGAAGTCCTTAAGCTTGATCCTGCTGTAATTGGCACCAATGACAATTT
CTTTGAGTTAGGAGGAAATAGTCTGCAGGCTGTGGTTTTAATTAACAAAATAAACAAAATATACAACACGGTATTTTCTA
TCACAAATCTATACGAGACCTTAACTATAAAAGGATTAGCAGTGCTGCTTAATTTCTATTTAATTCAGAAAAACGAATTT
GATATGGTACTTCAGGAAGAAGATCAAGATGAAATTATTCTGTAA

Upstream 100 bases:

>100_bases
TATATATTGAAAATTACACAGTTAGATACCCTTCCTTAGAATCTGGAAACTACGATACATTTAAAACTAAAAAATTTTAT
TATTTATAAATAAAGATAAA

Downstream 100 bases:

>100_bases
AGTTTCTAAAGACCAAAATAATCATTAACAAATAAAATAAAGACCCGGCAATGCTGGACTTAAATCAATTTTTATGAAAA
ATGACATCTTAAATAAACTT

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2894; Mature: 2894

Protein sequence:

>2894_residues
MNHINDKIAKDYWYKKNNRIVYTKEGFSENTSVDFTIVDAGRLSYFYKVTGENTDAEFTVLIALYNLLLQRYIVDGNVSF
LKSFLDSQIGLLSYEFQPIGKKTVKEFIQETKQEIQEVYKHAPYYKTEKEKANVEYIPFQFNYGTENKLNESFSELSCRI
EKLENRDLKITLHYSSKFAENNLALHLLKNFGRLLEELEANINLSAVKISLVSNEEEKNLLYNLNSQKTDYNRALTLVEI
VENQVYKTPNDIAVICKEKSLTYGELNKLANQLSNYLIQQGVSEGDFVGVKLERSEKLLVSILAVLKAGATYVPLDVNYP
AERIAYIETDSNCKLVITGAVYDDFLESQEKYNIENISLNRKSDDTAYIIYTSGTTGNPKGVMITHQNAVALIHWAQEEF
NPENFEIVYAATSHCFDLSIYEMFYPLSVGKRIKILNNALEIGPELTKDKNILLNTVPSSIRNILAEGFSLENVSIINLA
GEPFPVDIAKKLLQTNAEIRNLYGPSEDTTYSTCYKLSSAKNYQTIPIGKAISNTQAYILDEELQLVPMGTIGKLYLSGD
GIANGYLNKPELTAAKFIENPFAEGHKMYDTGDLVKWMPDGNLAFLGRKDHQIKLRGYRIELEEIENVISSFSENIGQAV
VAVRKNNGEDFLAAYFTEIENVSKTDLRAYLEKQLPAYMIPSYFTAVEKIPLTPNGKINKDALSEITDAFIVKNEYEAPS
DAVENELVEIWEQTLGISPIGVNDHFFELGGHSLMISQIINAIYKNLNKSVPYKVFYTNPTIKDLRKSLKDQEYLPIPLT
PYSESYPLTHSQNRLWMLSQLEGGNEAYQISGAVVLKGQLNAYNFCNAFDHVITHHEVLRTIFKKNEEGTVKQYIIPDNE
FHFAIENKDFSTSTSPYEEIQSYIGEKNKESYNLAEAPLFKASLLKTAADNFVFYLSIHHLISDGWSLKVLTAQVLEYYT
ILESGNVIPSPEHKIQFKDYAAWTQDEQNKKNYQLAQEYWLKQFEETVPVLQLPGYNGRPAVKTYAGNQYRHTFSKELFT
ELKNLSKGYQVTLFTALMAGVKTLLSRYASQNDIVIGTPIAGREHPDLEHQIGLYINTLAVRTLLNPKETFSALLQREGK
QLLEAYEHQNYPFDALVEQLKLSRDTSRSPLFDIMVVLQNQHQVSNFIDKKSSEITIEDFEISSEVSAFDIVFTFTEKET
LELEILYNTDIYTAEYIERLSAHLENLLQQVVKKPQVLLEEIELVSEDEKVILLNEFNDTDFVFDTDKTVIDHFLQQVRK
TPQKTAVIVDDQTLTYAELDEMSNKLANYLIENYQLGKGNFAAVKLERGLYLIISLLGILKTGAAYVPVDINYPENRIKD
ILDDVSPKAIIDDAFWNDFDSNESSALQPKTLPKGTDLAYVIYTSGSTGKPKGVMIAHQSLVNLCFWHKKAYNVDENSRG
TLFSGVAFDASVWEIYPYLISGAVLYPIQKDEIRLQIPELVSFLVKNEITHSYLPSKICQDLMAETNLKLPALILTGGER
LNYAVDTSLQVFNNYGPTENTVVTTYYDCKKALNEKVSIGKPVANTQVYILSENLKLQPVGVIGELCISGIGLSKGYLNQ
PELTKEKFIQNPFEPEEKLYKTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNAVVLVKEVKNE
PFIIAYYTTGKSVDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKVDLSKLPAISESDIVKKEYIAPANQTEEKIAV
IWQELLGHQKIGAGDDFFELGGHSLLLTKLLNEYQRVFKIAVNLKTLYTNSSLKSHAALLINSKEEIAVIEKLSYQEFYD
LSPSQVRYWLLYKINGKSKEFNIYSTFNLPENLNTAVFEQAFNILLERHEILRSLFAEEAGMPKQKIIQNLAVRIPVFES
ETEIKLHVFEYEFDLELDLLFRAAVLKKGAGYSLYFNMHHSIGDGWSMGIISRDLMEIYNALLEGRIAQLPELTIQYKDY
AQWQNNVLQSQEIKIQENYWKEQFAGTLPYLQLPSDYISKLKKAETSSSYTLFISDEKKKKIEELSRKNGASVFAVFAAV
LKVLLYRLTSEEDIILGIPTANRNHYQLKNLAGCFINTLMLRDTINSNFSFETWLAKVNETLINALTHQNYPFEKVLELI
DIPQDDNRFPLSPVFLNMVDFDAGSLDTITAFTSTHEVLNTAPKFDFECYIKSFENGYSINCVYDHELFKKETIQYWINA
YLSIIDQVIENDKKALFEIKIFEDFIYQENDLKPVNDFGFFEASEIQQSIAQRFEKQVELFPDREAVASKNTVLTYKKLN
NCANHLAQQIIEKASTETKRVALLLNHNETSVIGMLGVLKAGYAYVPIDANSPLSRIQYIIEDSGCDQLVCNEVTVEKAN
QLKKELPQLSITKLSENYNLPEILNPKQSSSPLAEAYVLYTSGSTGMPKGVLQIQKNVLHFIRVYTNNVHIAIQDNLSVF
STYTFDASVKDIYGAILNGAKVSIYDIVENGLDSLSEWLLAENITIIHMVPTIYRNFLKGLKKDEAVPTVRLVDLGGESC
HKSDLELFKEHFLEGAFLVNDYGPTESTIVAQKFLSHESELTRNNMPLGKSVEETKVFLLDENNKPKGIYQTGEIVFKSD
YLSLGYLNRQELTDKVFTTDPLTGNGRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRIELSEIEYQLEQIEFINEAVV
LLKELQENSYITAYVRSEEILDVTKIKLLLGKILPKYMIPAIYISMENFPLTRTGKIERKALPDPVISDLKTVPYEAPAN
DVESRLVHIWAEVLKLDPAVIGTNDNFFELGGNSLQAVVLINKINKIYNTVFSITNLYETLTIKGLAVLLNFYLIQKNEF
DMVLQEEDQDEIIL

Sequences:

>Translated_2894_residues
MNHINDKIAKDYWYKKNNRIVYTKEGFSENTSVDFTIVDAGRLSYFYKVTGENTDAEFTVLIALYNLLLQRYIVDGNVSF
LKSFLDSQIGLLSYEFQPIGKKTVKEFIQETKQEIQEVYKHAPYYKTEKEKANVEYIPFQFNYGTENKLNESFSELSCRI
EKLENRDLKITLHYSSKFAENNLALHLLKNFGRLLEELEANINLSAVKISLVSNEEEKNLLYNLNSQKTDYNRALTLVEI
VENQVYKTPNDIAVICKEKSLTYGELNKLANQLSNYLIQQGVSEGDFVGVKLERSEKLLVSILAVLKAGATYVPLDVNYP
AERIAYIETDSNCKLVITGAVYDDFLESQEKYNIENISLNRKSDDTAYIIYTSGTTGNPKGVMITHQNAVALIHWAQEEF
NPENFEIVYAATSHCFDLSIYEMFYPLSVGKRIKILNNALEIGPELTKDKNILLNTVPSSIRNILAEGFSLENVSIINLA
GEPFPVDIAKKLLQTNAEIRNLYGPSEDTTYSTCYKLSSAKNYQTIPIGKAISNTQAYILDEELQLVPMGTIGKLYLSGD
GIANGYLNKPELTAAKFIENPFAEGHKMYDTGDLVKWMPDGNLAFLGRKDHQIKLRGYRIELEEIENVISSFSENIGQAV
VAVRKNNGEDFLAAYFTEIENVSKTDLRAYLEKQLPAYMIPSYFTAVEKIPLTPNGKINKDALSEITDAFIVKNEYEAPS
DAVENELVEIWEQTLGISPIGVNDHFFELGGHSLMISQIINAIYKNLNKSVPYKVFYTNPTIKDLRKSLKDQEYLPIPLT
PYSESYPLTHSQNRLWMLSQLEGGNEAYQISGAVVLKGQLNAYNFCNAFDHVITHHEVLRTIFKKNEEGTVKQYIIPDNE
FHFAIENKDFSTSTSPYEEIQSYIGEKNKESYNLAEAPLFKASLLKTAADNFVFYLSIHHLISDGWSLKVLTAQVLEYYT
ILESGNVIPSPEHKIQFKDYAAWTQDEQNKKNYQLAQEYWLKQFEETVPVLQLPGYNGRPAVKTYAGNQYRHTFSKELFT
ELKNLSKGYQVTLFTALMAGVKTLLSRYASQNDIVIGTPIAGREHPDLEHQIGLYINTLAVRTLLNPKETFSALLQREGK
QLLEAYEHQNYPFDALVEQLKLSRDTSRSPLFDIMVVLQNQHQVSNFIDKKSSEITIEDFEISSEVSAFDIVFTFTEKET
LELEILYNTDIYTAEYIERLSAHLENLLQQVVKKPQVLLEEIELVSEDEKVILLNEFNDTDFVFDTDKTVIDHFLQQVRK
TPQKTAVIVDDQTLTYAELDEMSNKLANYLIENYQLGKGNFAAVKLERGLYLIISLLGILKTGAAYVPVDINYPENRIKD
ILDDVSPKAIIDDAFWNDFDSNESSALQPKTLPKGTDLAYVIYTSGSTGKPKGVMIAHQSLVNLCFWHKKAYNVDENSRG
TLFSGVAFDASVWEIYPYLISGAVLYPIQKDEIRLQIPELVSFLVKNEITHSYLPSKICQDLMAETNLKLPALILTGGER
LNYAVDTSLQVFNNYGPTENTVVTTYYDCKKALNEKVSIGKPVANTQVYILSENLKLQPVGVIGELCISGIGLSKGYLNQ
PELTKEKFIQNPFEPEEKLYKTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNAVVLVKEVKNE
PFIIAYYTTGKSVDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKVDLSKLPAISESDIVKKEYIAPANQTEEKIAV
IWQELLGHQKIGAGDDFFELGGHSLLLTKLLNEYQRVFKIAVNLKTLYTNSSLKSHAALLINSKEEIAVIEKLSYQEFYD
LSPSQVRYWLLYKINGKSKEFNIYSTFNLPENLNTAVFEQAFNILLERHEILRSLFAEEAGMPKQKIIQNLAVRIPVFES
ETEIKLHVFEYEFDLELDLLFRAAVLKKGAGYSLYFNMHHSIGDGWSMGIISRDLMEIYNALLEGRIAQLPELTIQYKDY
AQWQNNVLQSQEIKIQENYWKEQFAGTLPYLQLPSDYISKLKKAETSSSYTLFISDEKKKKIEELSRKNGASVFAVFAAV
LKVLLYRLTSEEDIILGIPTANRNHYQLKNLAGCFINTLMLRDTINSNFSFETWLAKVNETLINALTHQNYPFEKVLELI
DIPQDDNRFPLSPVFLNMVDFDAGSLDTITAFTSTHEVLNTAPKFDFECYIKSFENGYSINCVYDHELFKKETIQYWINA
YLSIIDQVIENDKKALFEIKIFEDFIYQENDLKPVNDFGFFEASEIQQSIAQRFEKQVELFPDREAVASKNTVLTYKKLN
NCANHLAQQIIEKASTETKRVALLLNHNETSVIGMLGVLKAGYAYVPIDANSPLSRIQYIIEDSGCDQLVCNEVTVEKAN
QLKKELPQLSITKLSENYNLPEILNPKQSSSPLAEAYVLYTSGSTGMPKGVLQIQKNVLHFIRVYTNNVHIAIQDNLSVF
STYTFDASVKDIYGAILNGAKVSIYDIVENGLDSLSEWLLAENITIIHMVPTIYRNFLKGLKKDEAVPTVRLVDLGGESC
HKSDLELFKEHFLEGAFLVNDYGPTESTIVAQKFLSHESELTRNNMPLGKSVEETKVFLLDENNKPKGIYQTGEIVFKSD
YLSLGYLNRQELTDKVFTTDPLTGNGRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRIELSEIEYQLEQIEFINEAVV
LLKELQENSYITAYVRSEEILDVTKIKLLLGKILPKYMIPAIYISMENFPLTRTGKIERKALPDPVISDLKTVPYEAPAN
DVESRLVHIWAEVLKLDPAVIGTNDNFFELGGNSLQAVVLINKINKIYNTVFSITNLYETLTIKGLAVLLNFYLIQKNEF
DMVLQEEDQDEIIL
>Mature_2894_residues
MNHINDKIAKDYWYKKNNRIVYTKEGFSENTSVDFTIVDAGRLSYFYKVTGENTDAEFTVLIALYNLLLQRYIVDGNVSF
LKSFLDSQIGLLSYEFQPIGKKTVKEFIQETKQEIQEVYKHAPYYKTEKEKANVEYIPFQFNYGTENKLNESFSELSCRI
EKLENRDLKITLHYSSKFAENNLALHLLKNFGRLLEELEANINLSAVKISLVSNEEEKNLLYNLNSQKTDYNRALTLVEI
VENQVYKTPNDIAVICKEKSLTYGELNKLANQLSNYLIQQGVSEGDFVGVKLERSEKLLVSILAVLKAGATYVPLDVNYP
AERIAYIETDSNCKLVITGAVYDDFLESQEKYNIENISLNRKSDDTAYIIYTSGTTGNPKGVMITHQNAVALIHWAQEEF
NPENFEIVYAATSHCFDLSIYEMFYPLSVGKRIKILNNALEIGPELTKDKNILLNTVPSSIRNILAEGFSLENVSIINLA
GEPFPVDIAKKLLQTNAEIRNLYGPSEDTTYSTCYKLSSAKNYQTIPIGKAISNTQAYILDEELQLVPMGTIGKLYLSGD
GIANGYLNKPELTAAKFIENPFAEGHKMYDTGDLVKWMPDGNLAFLGRKDHQIKLRGYRIELEEIENVISSFSENIGQAV
VAVRKNNGEDFLAAYFTEIENVSKTDLRAYLEKQLPAYMIPSYFTAVEKIPLTPNGKINKDALSEITDAFIVKNEYEAPS
DAVENELVEIWEQTLGISPIGVNDHFFELGGHSLMISQIINAIYKNLNKSVPYKVFYTNPTIKDLRKSLKDQEYLPIPLT
PYSESYPLTHSQNRLWMLSQLEGGNEAYQISGAVVLKGQLNAYNFCNAFDHVITHHEVLRTIFKKNEEGTVKQYIIPDNE
FHFAIENKDFSTSTSPYEEIQSYIGEKNKESYNLAEAPLFKASLLKTAADNFVFYLSIHHLISDGWSLKVLTAQVLEYYT
ILESGNVIPSPEHKIQFKDYAAWTQDEQNKKNYQLAQEYWLKQFEETVPVLQLPGYNGRPAVKTYAGNQYRHTFSKELFT
ELKNLSKGYQVTLFTALMAGVKTLLSRYASQNDIVIGTPIAGREHPDLEHQIGLYINTLAVRTLLNPKETFSALLQREGK
QLLEAYEHQNYPFDALVEQLKLSRDTSRSPLFDIMVVLQNQHQVSNFIDKKSSEITIEDFEISSEVSAFDIVFTFTEKET
LELEILYNTDIYTAEYIERLSAHLENLLQQVVKKPQVLLEEIELVSEDEKVILLNEFNDTDFVFDTDKTVIDHFLQQVRK
TPQKTAVIVDDQTLTYAELDEMSNKLANYLIENYQLGKGNFAAVKLERGLYLIISLLGILKTGAAYVPVDINYPENRIKD
ILDDVSPKAIIDDAFWNDFDSNESSALQPKTLPKGTDLAYVIYTSGSTGKPKGVMIAHQSLVNLCFWHKKAYNVDENSRG
TLFSGVAFDASVWEIYPYLISGAVLYPIQKDEIRLQIPELVSFLVKNEITHSYLPSKICQDLMAETNLKLPALILTGGER
LNYAVDTSLQVFNNYGPTENTVVTTYYDCKKALNEKVSIGKPVANTQVYILSENLKLQPVGVIGELCISGIGLSKGYLNQ
PELTKEKFIQNPFEPEEKLYKTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNAVVLVKEVKNE
PFIIAYYTTGKSVDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKVDLSKLPAISESDIVKKEYIAPANQTEEKIAV
IWQELLGHQKIGAGDDFFELGGHSLLLTKLLNEYQRVFKIAVNLKTLYTNSSLKSHAALLINSKEEIAVIEKLSYQEFYD
LSPSQVRYWLLYKINGKSKEFNIYSTFNLPENLNTAVFEQAFNILLERHEILRSLFAEEAGMPKQKIIQNLAVRIPVFES
ETEIKLHVFEYEFDLELDLLFRAAVLKKGAGYSLYFNMHHSIGDGWSMGIISRDLMEIYNALLEGRIAQLPELTIQYKDY
AQWQNNVLQSQEIKIQENYWKEQFAGTLPYLQLPSDYISKLKKAETSSSYTLFISDEKKKKIEELSRKNGASVFAVFAAV
LKVLLYRLTSEEDIILGIPTANRNHYQLKNLAGCFINTLMLRDTINSNFSFETWLAKVNETLINALTHQNYPFEKVLELI
DIPQDDNRFPLSPVFLNMVDFDAGSLDTITAFTSTHEVLNTAPKFDFECYIKSFENGYSINCVYDHELFKKETIQYWINA
YLSIIDQVIENDKKALFEIKIFEDFIYQENDLKPVNDFGFFEASEIQQSIAQRFEKQVELFPDREAVASKNTVLTYKKLN
NCANHLAQQIIEKASTETKRVALLLNHNETSVIGMLGVLKAGYAYVPIDANSPLSRIQYIIEDSGCDQLVCNEVTVEKAN
QLKKELPQLSITKLSENYNLPEILNPKQSSSPLAEAYVLYTSGSTGMPKGVLQIQKNVLHFIRVYTNNVHIAIQDNLSVF
STYTFDASVKDIYGAILNGAKVSIYDIVENGLDSLSEWLLAENITIIHMVPTIYRNFLKGLKKDEAVPTVRLVDLGGESC
HKSDLELFKEHFLEGAFLVNDYGPTESTIVAQKFLSHESELTRNNMPLGKSVEETKVFLLDENNKPKGIYQTGEIVFKSD
YLSLGYLNRQELTDKVFTTDPLTGNGRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRIELSEIEYQLEQIEFINEAVV
LLKELQENSYITAYVRSEEILDVTKIKLLLGKILPKYMIPAIYISMENFPLTRTGKIERKALPDPVISDLKTVPYEAPAN
DVESRLVHIWAEVLKLDPAVIGTNDNFFELGGNSLQAVVLINKINKIYNTVFSITNLYETLTIKGLAVLLNFYLIQKNEF
DMVLQEEDQDEIIL

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=633, Percent_Identity=24.0126382306477, Blast_Score=112, Evalue=6e-24,
Organism=Homo sapiens, GI156151445, Length=379, Percent_Identity=25.065963060686, Blast_Score=82, Evalue=5e-15,
Organism=Homo sapiens, GI38505220, Length=504, Percent_Identity=23.4126984126984, Blast_Score=77, Evalue=2e-13,
Organism=Escherichia coli, GI1786801, Length=1070, Percent_Identity=27.5700934579439, Blast_Score=332, Evalue=2e-91,
Organism=Escherichia coli, GI1786810, Length=528, Percent_Identity=24.6212121212121, Blast_Score=111, Evalue=7e-25,
Organism=Escherichia coli, GI145693145, Length=544, Percent_Identity=22.0588235294118, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1788107, Length=547, Percent_Identity=21.5722120658135, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17550940, Length=1138, Percent_Identity=23.6379613356766, Blast_Score=202, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17556356, Length=551, Percent_Identity=29.4010889292196, Blast_Score=166, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17538037, Length=515, Percent_Identity=22.3300970873786, Blast_Score=91, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994690, Length=376, Percent_Identity=21.2765957446809, Blast_Score=89, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994694, Length=376, Percent_Identity=21.2765957446809, Blast_Score=89, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994703, Length=376, Percent_Identity=21.2765957446809, Blast_Score=89, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32563687, Length=491, Percent_Identity=23.4215885947047, Blast_Score=88, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17557194, Length=512, Percent_Identity=21.875, Blast_Score=86, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531443, Length=523, Percent_Identity=21.7973231357553, Blast_Score=81, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17558820, Length=487, Percent_Identity=24.0246406570842, Blast_Score=77, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560308, Length=410, Percent_Identity=21.219512195122, Blast_Score=74, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147511, Length=162, Percent_Identity=34.5679012345679, Blast_Score=70, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=867, Percent_Identity=26.4129181084198, Blast_Score=260, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6319699, Length=380, Percent_Identity=24.4736842105263, Blast_Score=66, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24648676, Length=599, Percent_Identity=28.0467445742905, Blast_Score=194, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24582852, Length=456, Percent_Identity=24.5614035087719, Blast_Score=84, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581924, Length=546, Percent_Identity=21.4285714285714, Blast_Score=70, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 329388; Mature: 329388

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHINDKIAKDYWYKKNNRIVYTKEGFSENTSVDFTIVDAGRLSYFYKVTGENTDAEFTV
CCCCHHHHHHHHHEECCCEEEEEECCCCCCCEEEEEEEECCCEEEEEEEECCCCCCHHHH
LIALYNLLLQRYIVDGNVSFLKSFLDSQIGLLSYEFQPIGKKTVKEFIQETKQEIQEVYK
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
HAPYYKTEKEKANVEYIPFQFNYGTENKLNESFSELSCRIEKLENRDLKITLHYSSKFAE
HCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
NNLALHLLKNFGRLLEELEANINLSAVKISLVSNEEEKNLLYNLNSQKTDYNRALTLVEI
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH
VENQVYKTPNDIAVICKEKSLTYGELNKLANQLSNYLIQQGVSEGDFVGVKLERSEKLLV
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHH
SILAVLKAGATYVPLDVNYPAERIAYIETDSNCKLVITGAVYDDFLESQEKYNIENISLN
HHHHHHHCCCEEEEEECCCCHHHEEEEEECCCCEEEEECHHHHHHHHHHHHCCCCEEEEC
RKSDDTAYIIYTSGTTGNPKGVMITHQNAVALIHWAQEEFNPENFEIVYAATSHCFDLSI
CCCCCCEEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHCCCCCEEEEEEECCCEEEEEH
YEMFYPLSVGKRIKILNNALEIGPELTKDKNILLNTVPSSIRNILAEGFSLENVSIINLA
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEC
GEPFPVDIAKKLLQTNAEIRNLYGPSEDTTYSTCYKLSSAKNYQTIPIGKAISNTQAYIL
CCCCCHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCEEEEE
DEELQLVPMGTIGKLYLSGDGIANGYLNKPELTAAKFIENPFAEGHKMYDTGDLVKWMPD
ECCCEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCHHHCCCCEECCCCEEEECCC
GNLAFLGRKDHQIKLRGYRIELEEIENVISSFSENIGQAVVAVRKNNGEDFLAAYFTEIE
CCEEEEECCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHC
NVSKTDLRAYLEKQLPAYMIPSYFTAVEKIPLTPNGKINKDALSEITDAFIVKNEYEAPS
CCCHHHHHHHHHHCCCHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEECCCCCCH
DAVENELVEIWEQTLGISPIGVNDHFFELGGHSLMISQIINAIYKNLNKSVPYKVFYTNP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
TIKDLRKSLKDQEYLPIPLTPYSESYPLTHSQNRLWMLSQLEGGNEAYQISGAVVLKGQL
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECEEEEEECC
NAYNFCNAFDHVITHHEVLRTIFKKNEEGTVKQYIIPDNEFHFAIENKDFSTSTSPYEEI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHHH
QSYIGEKNKESYNLAEAPLFKASLLKTAADNFVFYLSIHHLISDGWSLKVLTAQVLEYYT
HHHHCCCCCCCCCCHHCCHHHHHHHHHHHCCEEEEEEEHHHHCCCCEEEHHHHHHHHHHH
ILESGNVIPSPEHKIQFKDYAAWTQDEQNKKNYQLAQEYWLKQFEETVPVLQLPGYNGRP
HHHCCCCCCCCCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
AVKTYAGNQYRHTFSKELFTELKNLSKGYQVTLFTALMAGVKTLLSRYASQNDIVIGTPI
CEEECCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEECCC
AGREHPDLEHQIGLYINTLAVRTLLNPKETFSALLQREGKQLLEAYEHQNYPFDALVEQL
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KLSRDTSRSPLFDIMVVLQNQHQVSNFIDKKSSEITIEDFEISSEVSAFDIVFTFTEKET
HHCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEECCCCE
LELEILYNTDIYTAEYIERLSAHLENLLQQVVKKPQVLLEEIELVSEDEKVILLNEFNDT
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEECCCC
DFVFDTDKTVIDHFLQQVRKTPQKTAVIVDDQTLTYAELDEMSNKLANYLIENYQLGKGN
CEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEECCCC
FAAVKLERGLYLIISLLGILKTGAAYVPVDINYPENRIKDILDDVSPKAIIDDAFWNDFD
EEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEECHHHCCCCC
SNESSALQPKTLPKGTDLAYVIYTSGSTGKPKGVMIAHQSLVNLCFWHKKAYNVDENSRG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCC
TLFSGVAFDASVWEIYPYLISGAVLYPIQKDEIRLQIPELVSFLVKNEITHSYLPSKICQ
CEEECEECCCHHHHHHHHHHCCEEEEEEECCCEEEEHHHHHHHHHHHCCHHHHCHHHHHH
DLMAETNLKLPALILTGGERLNYAVDTSLQVFNNYGPTENTVVTTYYDCKKALNEKVSIG
HHHHHCCCCCCEEEEECCCEEEEEECCHHHHHHCCCCCCCCEEEEEHHHHHHHCCCCCCC
KPVANTQVYILSENLKLQPVGVIGELCISGIGLSKGYLNQPELTKEKFIQNPFEPEEKLY
CCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHH
KTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNAVVLVKEVKNE
HCCCHHHHCCCCCEEEECCCCCEEEEECCEEEHHHHHHHHHHHHHHHHHHEEEEEECCCC
PFIIAYYTTGKSVDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKVDLSKLPAISES
CEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEHHHCCCCCCC
DIVKKEYIAPANQTEEKIAVIWQELLGHQKIGAGDDFFELGGHSLLLTKLLNEYQRVFKI
CCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHH
AVNLKTLYTNSSLKSHAALLINSKEEIAVIEKLSYQEFYDLSPSQVRYWLLYKINGKSKE
HHHHEEEEECCCCCCCEEEEECCCHHHHHHHHHCHHHHHCCCCCCEEEEEEEEECCCCCE
FNIYSTFNLPENLNTAVFEQAFNILLERHEILRSLFAEEAGMPKQKIIQNLAVRIPVFES
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECC
ETEIKLHVFEYEFDLELDLLFRAAVLKKGAGYSLYFNMHHSIGDGWSMGIISRDLMEIYN
CCEEEEEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
ALLEGRIAQLPELTIQYKDYAQWQNNVLQSQEIKIQENYWKEQFAGTLPYLQLPSDYISK
HHHCCHHHCCCCEEEEHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCEEECCHHHHHH
LKKAETSSSYTLFISDEKKKKIEELSRKNGASVFAVFAAVLKVLLYRLTSEEDIILGIPT
HHHCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCC
ANRNHYQLKNLAGCFINTLMLRDTINSNFSFETWLAKVNETLINALTHQNYPFEKVLELI
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DIPQDDNRFPLSPVFLNMVDFDAGSLDTITAFTSTHEVLNTAPKFDFECYIKSFENGYSI
CCCCCCCCCCCCHHEEEEEECCCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHCCCCEEE
NCVYDHELFKKETIQYWINAYLSIIDQVIENDKKALFEIKIFEDFIYQENDLKPVNDFGF
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEHHHHHCCCCCCCCCCCCCC
FEASEIQQSIAQRFEKQVELFPDREAVASKNTVLTYKKLNNCANHLAQQIIEKASTETKR
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEE
VALLLNHNETSVIGMLGVLKAGYAYVPIDANSPLSRIQYIIEDSGCDQLVCNEVTVEKAN
EEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHCHHHHHHHH
QLKKELPQLSITKLSENYNLPEILNPKQSSSPLAEAYVLYTSGSTGMPKGVLQIQKNVLH
HHHHHCCCCEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
FIRVYTNNVHIAIQDNLSVFSTYTFDASVKDIYGAILNGAKVSIYDIVENGLDSLSEWLL
HHHHEECCEEEEEECCCEEEEEEEECCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHH
AENITIIHMVPTIYRNFLKGLKKDEAVPTVRLVDLGGESCHKSDLELFKEHFLEGAFLVN
HCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEE
DYGPTESTIVAQKFLSHESELTRNNMPLGKSVEETKVFLLDENNKPKGIYQTGEIVFKSD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCEEEEEC
YLSLGYLNRQELTDKVFTTDPLTGNGRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRI
CEEECCCCHHHHHCHHEECCCCCCCCEEEECCCEEEEECCCCHHHHHCCCCEEEEEEEEE
ELSEIEYQLEQIEFINEAVVLLKELQENSYITAYVRSEEILDVTKIKLLLGKILPKYMIP
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
AIYISMENFPLTRTGKIERKALPDPVISDLKTVPYEAPANDVESRLVHIWAEVLKLDPAV
EEEEEECCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
IGTNDNFFELGGNSLQAVVLINKINKIYNTVFSITNLYETLTIKGLAVLLNFYLIQKNEF
ECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
DMVLQEEDQDEIIL
CEEEECCCCCCCCC
>Mature Secondary Structure
MNHINDKIAKDYWYKKNNRIVYTKEGFSENTSVDFTIVDAGRLSYFYKVTGENTDAEFTV
CCCCHHHHHHHHHEECCCEEEEEECCCCCCCEEEEEEEECCCEEEEEEEECCCCCCHHHH
LIALYNLLLQRYIVDGNVSFLKSFLDSQIGLLSYEFQPIGKKTVKEFIQETKQEIQEVYK
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
HAPYYKTEKEKANVEYIPFQFNYGTENKLNESFSELSCRIEKLENRDLKITLHYSSKFAE
HCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
NNLALHLLKNFGRLLEELEANINLSAVKISLVSNEEEKNLLYNLNSQKTDYNRALTLVEI
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH
VENQVYKTPNDIAVICKEKSLTYGELNKLANQLSNYLIQQGVSEGDFVGVKLERSEKLLV
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHH
SILAVLKAGATYVPLDVNYPAERIAYIETDSNCKLVITGAVYDDFLESQEKYNIENISLN
HHHHHHHCCCEEEEEECCCCHHHEEEEEECCCCEEEEECHHHHHHHHHHHHCCCCEEEEC
RKSDDTAYIIYTSGTTGNPKGVMITHQNAVALIHWAQEEFNPENFEIVYAATSHCFDLSI
CCCCCCEEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHCCCCCEEEEEEECCCEEEEEH
YEMFYPLSVGKRIKILNNALEIGPELTKDKNILLNTVPSSIRNILAEGFSLENVSIINLA
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEC
GEPFPVDIAKKLLQTNAEIRNLYGPSEDTTYSTCYKLSSAKNYQTIPIGKAISNTQAYIL
CCCCCHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCEEEEE
DEELQLVPMGTIGKLYLSGDGIANGYLNKPELTAAKFIENPFAEGHKMYDTGDLVKWMPD
ECCCEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCHHHCCCCEECCCCEEEECCC
GNLAFLGRKDHQIKLRGYRIELEEIENVISSFSENIGQAVVAVRKNNGEDFLAAYFTEIE
CCEEEEECCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHC
NVSKTDLRAYLEKQLPAYMIPSYFTAVEKIPLTPNGKINKDALSEITDAFIVKNEYEAPS
CCCHHHHHHHHHHCCCHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEECCCCCCH
DAVENELVEIWEQTLGISPIGVNDHFFELGGHSLMISQIINAIYKNLNKSVPYKVFYTNP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
TIKDLRKSLKDQEYLPIPLTPYSESYPLTHSQNRLWMLSQLEGGNEAYQISGAVVLKGQL
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECEEEEEECC
NAYNFCNAFDHVITHHEVLRTIFKKNEEGTVKQYIIPDNEFHFAIENKDFSTSTSPYEEI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHHH
QSYIGEKNKESYNLAEAPLFKASLLKTAADNFVFYLSIHHLISDGWSLKVLTAQVLEYYT
HHHHCCCCCCCCCCHHCCHHHHHHHHHHHCCEEEEEEEHHHHCCCCEEEHHHHHHHHHHH
ILESGNVIPSPEHKIQFKDYAAWTQDEQNKKNYQLAQEYWLKQFEETVPVLQLPGYNGRP
HHHCCCCCCCCCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
AVKTYAGNQYRHTFSKELFTELKNLSKGYQVTLFTALMAGVKTLLSRYASQNDIVIGTPI
CEEECCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEECCC
AGREHPDLEHQIGLYINTLAVRTLLNPKETFSALLQREGKQLLEAYEHQNYPFDALVEQL
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KLSRDTSRSPLFDIMVVLQNQHQVSNFIDKKSSEITIEDFEISSEVSAFDIVFTFTEKET
HHCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEEECCCCE
LELEILYNTDIYTAEYIERLSAHLENLLQQVVKKPQVLLEEIELVSEDEKVILLNEFNDT
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEECCCC
DFVFDTDKTVIDHFLQQVRKTPQKTAVIVDDQTLTYAELDEMSNKLANYLIENYQLGKGN
CEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEECCCC
FAAVKLERGLYLIISLLGILKTGAAYVPVDINYPENRIKDILDDVSPKAIIDDAFWNDFD
EEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEECHHHCCCCC
SNESSALQPKTLPKGTDLAYVIYTSGSTGKPKGVMIAHQSLVNLCFWHKKAYNVDENSRG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCC
TLFSGVAFDASVWEIYPYLISGAVLYPIQKDEIRLQIPELVSFLVKNEITHSYLPSKICQ
CEEECEECCCHHHHHHHHHHCCEEEEEEECCCEEEEHHHHHHHHHHHCCHHHHCHHHHHH
DLMAETNLKLPALILTGGERLNYAVDTSLQVFNNYGPTENTVVTTYYDCKKALNEKVSIG
HHHHHCCCCCCEEEEECCCEEEEEECCHHHHHHCCCCCCCCEEEEEHHHHHHHCCCCCCC
KPVANTQVYILSENLKLQPVGVIGELCISGIGLSKGYLNQPELTKEKFIQNPFEPEEKLY
CCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHH
KTGDLARWLPDGNLEYVGRKDNQVKIRGNRVELGEIEYVIREFDSAISNAVVLVKEVKNE
HCCCHHHHCCCCCEEEECCCCCEEEEECCEEEHHHHHHHHHHHHHHHHHHEEEEEECCCC
PFIIAYYTTGKSVDKKELRKYLKDKLADYMIPAYYVELETLQLNANGKVDLSKLPAISES
CEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCEEHHHCCCCCCC
DIVKKEYIAPANQTEEKIAVIWQELLGHQKIGAGDDFFELGGHSLLLTKLLNEYQRVFKI
CCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHH
AVNLKTLYTNSSLKSHAALLINSKEEIAVIEKLSYQEFYDLSPSQVRYWLLYKINGKSKE
HHHHEEEEECCCCCCCEEEEECCCHHHHHHHHHCHHHHHCCCCCCEEEEEEEEECCCCCE
FNIYSTFNLPENLNTAVFEQAFNILLERHEILRSLFAEEAGMPKQKIIQNLAVRIPVFES
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECC
ETEIKLHVFEYEFDLELDLLFRAAVLKKGAGYSLYFNMHHSIGDGWSMGIISRDLMEIYN
CCEEEEEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHH
ALLEGRIAQLPELTIQYKDYAQWQNNVLQSQEIKIQENYWKEQFAGTLPYLQLPSDYISK
HHHCCHHHCCCCEEEEHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCEEECCHHHHHH
LKKAETSSSYTLFISDEKKKKIEELSRKNGASVFAVFAAVLKVLLYRLTSEEDIILGIPT
HHHCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCC
ANRNHYQLKNLAGCFINTLMLRDTINSNFSFETWLAKVNETLINALTHQNYPFEKVLELI
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DIPQDDNRFPLSPVFLNMVDFDAGSLDTITAFTSTHEVLNTAPKFDFECYIKSFENGYSI
CCCCCCCCCCCCHHEEEEEECCCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHCCCCEEE
NCVYDHELFKKETIQYWINAYLSIIDQVIENDKKALFEIKIFEDFIYQENDLKPVNDFGF
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEHHHHHCCCCCCCCCCCCCC
FEASEIQQSIAQRFEKQVELFPDREAVASKNTVLTYKKLNNCANHLAQQIIEKASTETKR
CCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEE
VALLLNHNETSVIGMLGVLKAGYAYVPIDANSPLSRIQYIIEDSGCDQLVCNEVTVEKAN
EEEEEECCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCHHHCHHHHHHHH
QLKKELPQLSITKLSENYNLPEILNPKQSSSPLAEAYVLYTSGSTGMPKGVLQIQKNVLH
HHHHHCCCCEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
FIRVYTNNVHIAIQDNLSVFSTYTFDASVKDIYGAILNGAKVSIYDIVENGLDSLSEWLL
HHHHEECCEEEEEECCCEEEEEEEECCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHH
AENITIIHMVPTIYRNFLKGLKKDEAVPTVRLVDLGGESCHKSDLELFKEHFLEGAFLVN
HCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEE
DYGPTESTIVAQKFLSHESELTRNNMPLGKSVEETKVFLLDENNKPKGIYQTGEIVFKSD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEECCCEEEEEC
YLSLGYLNRQELTDKVFTTDPLTGNGRVYKSGDIGMMLPSGEIEFLQRKDSQVKINGLRI
CEEECCCCHHHHHCHHEECCCCCCCCEEEECCCEEEEECCCCHHHHHCCCCEEEEEEEEE
ELSEIEYQLEQIEFINEAVVLLKELQENSYITAYVRSEEILDVTKIKLLLGKILPKYMIP
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
AIYISMENFPLTRTGKIERKALPDPVISDLKTVPYEAPANDVESRLVHIWAEVLKLDPAV
EEEEEECCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
IGTNDNFFELGGNSLQAVVLINKINKIYNTVFSITNLYETLTIKGLAVLLNFYLIQKNEF
ECCCCCEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
DMVLQEEDQDEIIL
CEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]