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The map label for this gene is tycC [H]

Identifier: 146299847

GI number: 146299847

Start: 2485498

End: 2491914

Strand: Direct

Name: tycC [H]

Synonym: Fjoh_2089

Alternate gene names: 146299847

Gene position: 2485498-2491914 (Clockwise)

Preceding gene: 146299846

Following gene: 146299848

Centisome position: 40.77

GC content: 35.11

Gene sequence:

>6417_bases
ATGAAAAATGACATCTTAAATAAACTTCTTTCTCTTGGAGTTCAGCTGAAAATAATTGATGGTAATCTTAAAGTAAATGC
CCCAAAAGGAGTATTGACAAAAGAATTATTAGAAGAAATTAAAGAATACAAGGCCTATTTAATTAGTTTAATATCCTTTA
ATACATCTATTCCCAAAACTGAGATTAAAGAAAATTACGCCTTAACACCAACTCAGTATTTTATGTGGTTTACACATGAA
CATTTGGGCGGAAAAAGAGCATATAATATAACATCGACATTAAAACTGAAAGGAAAGCTGAACGAATTTCTTCTTGAAAA
AGCATTTCAGAAGGTTATAACACGTCATGAATCGCTTAGAACAGTTTTTAAGAAAGACGAGAATGATCAGGTTCAGCAGC
ATATTTTATCATCAGATGAAGTTCATTTTAAATTACAAAAGGCAGCATTGCAGCATTTTTCTGTAGAGCAGCTTCATAAC
CGCATTAAGTTAGAATACTTAAATACATTCGATCTGGAAAAAGGACCTTTGTTAAACGGTACTTTGTTAAAAACCAGCGA
AGAAGAACATATTTTAGTATTTGTATTACATCATATTATTGGCGACGGATGGTCATTACAGCTGCTGACTCGTGAGATTA
TGCTTGTCTATAACAGCTTGGCAAGTGCTGAAGAAGTACAATTGCAAGAACTGTCAATACAATACAAAGATTACAGCGAA
TGGCTGAATAAAAAGCTTATCAGCGATGAATACAACCAAAAACTTGAGTTTTGGAAAGAACAGTTTAAAACTAAATCTCC
CGCTTTGGAGCTAATTATGAATAAACGTCCGACTGTAAAAACGTATAACGGACGTATTTATAATCACGAATTTTCTAAGC
AGTTTTTAGGAGAACTAAATGCATTTGCTAAAGAGCAGCAAATGACTCTTTTCATGTTGTTAATGGGAAGTCTCAACGGA
TTATTTTATAAATATACAGGCCAGACCGATATTACATTAGGAACAACAGCAGCTGGAAGAGAACACACAGATTTGGAACA
TCAAATAGGATTGTACTCTAATGCATTAGCCATACGTACCAAATTTCACAAAGAGGATAGTTTCTTGGAGTTGATGCAAA
AACAAAAAAATACTCTAATCAAAGCGTATGAAAATAAAGAATATCCTTTTACTGCACTTGTTAATCATTTAAAACCGGCA
AAAGATCAAAGCAGATCAGCATTGTTTGATATTATGGTTTTACTGCAAAACCATCAGGGATTAGAAATTAATGACCAAAA
AGGAATCAATGGAATTACAGCATCTGAATATAATGAAATTGAAAGAGGTGTAAGCCAGTTGGACATTAGTTTTGTTTTTG
TAGAAAAAGAACACGGACTTTCTTTAAGTGTAGAATATAACACAGATATTTATAACCAAGACTTTATTACAGCTCTTTTA
TCTCATTTTGAAGAATTTGTAAAATCAGGTTTGCAAAATCCAAATCAACCCATAAATGATGTTGAGATTGTAACTGCAGC
AGAGAAAAATAAAATCCTGACGGAATTTAATCAGGACAATGTTTCTTCTGAAGTTTCTTTGACCGTAATCGATTTAATAA
AGTCAGCAGCAGCTGAAAATCCAAATAAAACAGCGCTTGTTTATCAGGAAGAAGAAATAAGTTATAGAACTTTAGATATA
TACAGCAGTAAATTAGCGAACTATTTACAGCAAAACCGCAATGTAAAAAAAGGGGATTTTGTTGGGATTGGACTGCAAAG
AAATTCCTGGAGCATTATAACTATTTTGGCCGTTTTAAAAACGGGTGCCGTATATGTGCCTATAGATCCGGATTACCCTG
AAGATAGAAGAAATTATATAGAAAAAGACAGTGGCTGTAAGTTTACAATAACAGCGGCTGTATTAGAAGAATTTAAAAAC
ATTTCGGATCGTTTTATCGGCGAATACAAAGCTGAGGTAAGTCCCGGTGATTTAGCCTACATTATATATACTTCTGGATC
TACAGGAAATCCAAAAGGTGTGCAGATAACCCACACATCTTTGACAGATTATGCAGTGACTTTTAAAAACTATTTCCAAT
TAACGTTGCACGATAGTATAGTACAGCAGGCAAGTATTTCTTTTGATACTTCGATAGAAGAAATTTTCCCAATTCTTGTC
AGTGGCGGAAGTATGGTGATTTATGATGGAAAAGGAGATTTTGAAACTCTGTTTCGTCTTTGTGAAAAACACAATGTAAC
AGTTTTAAGTACAAATCCATACGCATTGCAATATTTAAATGCGGCATACGATCAATTTGATCTTCAAATCAGAATATTAA
TAAGCGGGGGAGATGTTCTGCAGCCGGATTATATTCATAATTTATGGAATCACATCTCAGTTTACAACACTTACGGACCA
ACAGAAAGTACGGTATGTGCGACTTATTATCATGTAAACGAAAAACTAAACGCTGTTTCTATTGGAAAACCAATTGCAAA
CAGACAAGTATATATTATTGAACCCGAAAGTTCTCAATTAGCTCCAGTGGGCATTATTGGAGAACTCTGTATTTCTGGAA
AAGGATTATCAGCCGGTTATTTAAATCAGCCCGAACTTACCGCTGAAAAGTTTGTACAAAATCCTTTTATTAAAGGAGAG
AGAATGTATCGTACAGGCGATTTAGCATACTGGCTTCCTGATGGAAATATTGAGTATATAGGCAGAATCGACAGTCAGGT
TAAGATTCGTGGATTTAGAATTGAGCTGGGAGAGATTGAAACGGCCTTACTTCAATATTCACAAAATGTAAGACAGGCAG
TTGCTGCTGTAAAAGAAATCAACGGCGAAAAAGTACTAGCAGCTTATTACGTAAGCACACAGGAAATTGACAAATCAGAG
ATTCGCAGTTATCTTCAAGGAAAACTGCCGGAATATATGGTTCCTGGTTTTTATATTGCTTTAGACGTTCTTCCGTTAAC
ACCAAATGGAAAAACGGATAGAAAAGCGCTTCCTGAAATAAGCGGAGAAGACCTTATCAGAAAAGAATATGCAGCTCCAA
GAAATGCCGCAGAGCAGAATCTGGCTCAAATCTGGCAGGAAGTACTTGGCGTAGATCAGGTTGGTATTACAGATAATTTT
TTCGAACTCGGCGGACACAGTCTTGTTGCGGCACAGGTCATTAACCGAATCCAAAAACAGTTAAACAAAAAAGTTTCCTT
TAAAGATTTCTTCTCAAACCCAACTATAGAAGCCTTGTCAGCACGATTGAGCGATGCCGGTTATGTATCTATAACACCAG
CGCCAATTCAGGAAAGTTATCCGCTGACAGCCTCACAAAACCGACTTTGGCTTTTGAGCCAGCTTGACGGCGGTTCTCTG
GCTTATAATATTCCGTTTGCTTTCGAATTATCAGGAGCTTTGGATAAGGATAATTTCCAGGCCTCATTAAAAAAAGTAAT
CGAGCGTCATGAAATATTAAGAACCTATTTCAAATCAGACGAATCAGGAGTAGTCCGCCAGCATATTTTACAAGCAGATT
TAGTTAATTTTAAATTGATTGAAGAAGATTTTACTCAAATCGATAATCAGCAGAAATCTGTATCTAATTATCTGCAGCAG
CAAAACCATATTGCTTTTGATTTAGAAAAAGCACCTTTGCTTCGTGCCGGACTTGTAAAGCTTGAGGAGCAGAAACATAT
TTTCTTTTTAACGATGCACCATATCATTGGAGACGGCTGGTCGCTTGAACTGCTTATTTCTGAGGTTGTTAAAATTTATA
ATGCTCTAAATGAAGGAAAAGACGCAGATCTTCCGGTATTGAACATTCAATATAAAGACTATGCAGTCTGGCTTTCTAAT
GAGCTTGAGCAGGAAAAGCATCTTGTTTCTAAAGAATTCTGGATGAATCAGTTTACAGGTGAAATTCCAGTATTGGATCT
TCCTAGTTTTAATAAACGTCCGTTATCGCAGAGTTACAAAGGCGATAGTGTAAGTCATACATTTTCGCAGACTTTTTTAT
ACAAATTAAAATCCTATTCAAAAACTCAGGATGCCACCTTGTTTATGACTTTAATGGCAGGAGTAAAAACACTTCTTTAT
CGTTATACAGGCCAGAACGATCTGGTTATCGGGACACCTATTGCAGGCAGGGAACATCCGGATTTAGAAAATCAGGCTGG
ACTTTACCTCAATACACTTGCCATAAGAACACAGCTTAAGGAAAAATCACATTTTGCATCAATTTTAAATCAGGAAAAAG
AAACGTTGCTCGAAGCTTATCAGCATCAAAATTATCCTTTTGATGAACTTATCGGGAATCTGAACCTAAAGAGAGACATG
AGCCGTTCCGCATTATTTGATGTCATGGTGGTGCTGCAAAATCAGTCTCAGCTTCAAAATCTTTCCAGCGGAGATGCATT
AACAGGTCTTCAGATTAAGAATTATGAGTTTAAAAATAATACTTCACAATTTGACGTAAGTTTTGTTTTTGTTGAAAGAG
AAGAAGGGTTGTCTCTTACAATTCAGTACAATACAGATCTTTATGATTCACTTTTGATCAAAAGAATATCTGCTCATCTG
GAAAATTTAATGACTCAGGCATTAGAAAATCCTTCTCTTGCAGTTGAAGAACTGTCCTATATTACTCCAGATGAGAAACT
TCAGGTAACAGAGACTTTTAATGCTACTGCTGCGGAATATTCTCGTGATAAGACTATCATAGATAAATTTGAAGAACAGG
TTTTAAAAACTCCGGACCAAACCGCTGTTGTTTTTGAGGAAACAGAACTGAGTTATCAATCTTTAAATGCACTGTCTAAC
CAGCTTGGCGGTTATTTGAGAAAGCATTATGATATCCAGCCTGATGATCTAATCGGCATTAAGCTTGAGAGAAGTGAACG
TATGATGGTGGCAGTTCTGGGAATTTTAAAATCAGGAGGTGCTTATGTTCCAATAGATCTTGCTTACCCGCAGTCTAGAA
TTGAATACATTGAAAAAGACAGCAGCAGCAAACTTATTATTGATGAAAAAGTTCTTGAAGCATTTTACAAAGAAAAAGAT
GAATATTCGACATTAAACATTGTCAAAAACAATACTCCGTCAAATTTGGCTTATGTTATTTATACTTCTGGAACTACCGG
AAATCCTAAAGGAGTAATGGTAGAAAATAGAAATGCGGCAACTTTAATTGACTGGTCAAAAGAAGAATATGCTCATAGTG
TATTCGATATAGTTTACGCCGTTACTTCGTATTGTTTTGATTTATCGGTTTATGAATTTTTCTTCACTTTAACAACCGGA
AAAACATTGCGAGTACTAAAAAATGCATTAGATATAGAAACCTATATCAATAATGATAAGAATGTATTATTGAATACTGT
TCCTTCGGTAGTGAGAAAATTATTAGAAGACAAAGTTTCTTTAAAAAACATTAACGTGCTGAATATGGCAGGAGAAATCC
TTCCGACTGATATTATCGATAAGCTGCCTTTAGAGATCATGGAAGTAAGAAATCTTTACGGTCCGTCTGAAGATACAACA
TATAGTACGAGCTATTTAATAACTTCAAAAGGAAACAGAACAATTTCTGTCGGACGTCCAATATCAAATACACAGGCATG
GATACTGAACGAATCTCTTTTACCTGTTCCTGTTGGTATAGCAGGTAAATTATATCTTTCAGGAGAAGGAGTTACAAGAG
GATATTTAAACAAACCAGAACTTACTGCTGAAAAGTTTGTTAATAACCCTTTTGTTCAAGGTGGGGTAATGTATGACACA
GGCGATCTGGCTTATTGGCTTCCTGATGGGAACATAGAGTTTTTAGGAAGAAAAGATCATCAGGTTAAAATTCGTGGTTT
TAGAATAGAATTAGGAGAAATTGAAACCGCTGTTTCTAATTATTCAAGTACAGTAAAACAAGTTGTTGTTGATACAAAAG
AAATAGAATCAACTCAGGTTTTAGCAGCTTATTATACAGCCTCAGAAAATATCAATAAAGGAGAATTAAGAAAACATCTT
CAGAGTGTACTGCCAGAATTTATGGTTCCTGGTTATTTCATACAATTAGAAAATATGCCATTGACTCCAAACGGAAAAAT
TGACCGAAAGGCACTTCCCGAAGTATCAGAGAAGCATATTATCAAAAAAGAATATGTGGCACCCAAAACCAAAATAGAAA
AGTCATTAGTAACGATTTGGCAGGAGGTTTTAAAAGTAGATAGAATTGGTATTACAGATAATTTTTTCGAGCTGGGCGGC
CACAGTCTTATGGCAGGACAGCTTATTAATCGGGTAAACAAACAATTTGATGTGTCGATTAATATAAAAGAAATCTTCAT
GTCTCCAACAATTGAAATTCTGGCCTTAAATATAGAAAACACAAAATGGATAGAAGAAACTGTTTTAGAAGATTCTACTG
CAAAAATATTAATATAA

Upstream 100 bases:

>100_bases
GAAGATCAAGATGAAATTATTCTGTAAAGTTTCTAAAGACCAAAATAATCATTAACAAATAAAATAAAGACCCGGCAATG
CTGGACTTAAATCAATTTTT

Downstream 100 bases:

>100_bases
AAGCATATGGAAATACGTTTATTGATTAAAAGATTAAGAGAAGAAGGCGTAATAGTTAAGATGAAAAACGATCAGCTGGA
AATATCGCTGCTATATAATC

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2138; Mature: 2138

Protein sequence:

>2138_residues
MKNDILNKLLSLGVQLKIIDGNLKVNAPKGVLTKELLEEIKEYKAYLISLISFNTSIPKTEIKENYALTPTQYFMWFTHE
HLGGKRAYNITSTLKLKGKLNEFLLEKAFQKVITRHESLRTVFKKDENDQVQQHILSSDEVHFKLQKAALQHFSVEQLHN
RIKLEYLNTFDLEKGPLLNGTLLKTSEEEHILVFVLHHIIGDGWSLQLLTREIMLVYNSLASAEEVQLQELSIQYKDYSE
WLNKKLISDEYNQKLEFWKEQFKTKSPALELIMNKRPTVKTYNGRIYNHEFSKQFLGELNAFAKEQQMTLFMLLMGSLNG
LFYKYTGQTDITLGTTAAGREHTDLEHQIGLYSNALAIRTKFHKEDSFLELMQKQKNTLIKAYENKEYPFTALVNHLKPA
KDQSRSALFDIMVLLQNHQGLEINDQKGINGITASEYNEIERGVSQLDISFVFVEKEHGLSLSVEYNTDIYNQDFITALL
SHFEEFVKSGLQNPNQPINDVEIVTAAEKNKILTEFNQDNVSSEVSLTVIDLIKSAAAENPNKTALVYQEEEISYRTLDI
YSSKLANYLQQNRNVKKGDFVGIGLQRNSWSIITILAVLKTGAVYVPIDPDYPEDRRNYIEKDSGCKFTITAAVLEEFKN
ISDRFIGEYKAEVSPGDLAYIIYTSGSTGNPKGVQITHTSLTDYAVTFKNYFQLTLHDSIVQQASISFDTSIEEIFPILV
SGGSMVIYDGKGDFETLFRLCEKHNVTVLSTNPYALQYLNAAYDQFDLQIRILISGGDVLQPDYIHNLWNHISVYNTYGP
TESTVCATYYHVNEKLNAVSIGKPIANRQVYIIEPESSQLAPVGIIGELCISGKGLSAGYLNQPELTAEKFVQNPFIKGE
RMYRTGDLAYWLPDGNIEYIGRIDSQVKIRGFRIELGEIETALLQYSQNVRQAVAAVKEINGEKVLAAYYVSTQEIDKSE
IRSYLQGKLPEYMVPGFYIALDVLPLTPNGKTDRKALPEISGEDLIRKEYAAPRNAAEQNLAQIWQEVLGVDQVGITDNF
FELGGHSLVAAQVINRIQKQLNKKVSFKDFFSNPTIEALSARLSDAGYVSITPAPIQESYPLTASQNRLWLLSQLDGGSL
AYNIPFAFELSGALDKDNFQASLKKVIERHEILRTYFKSDESGVVRQHILQADLVNFKLIEEDFTQIDNQQKSVSNYLQQ
QNHIAFDLEKAPLLRAGLVKLEEQKHIFFLTMHHIIGDGWSLELLISEVVKIYNALNEGKDADLPVLNIQYKDYAVWLSN
ELEQEKHLVSKEFWMNQFTGEIPVLDLPSFNKRPLSQSYKGDSVSHTFSQTFLYKLKSYSKTQDATLFMTLMAGVKTLLY
RYTGQNDLVIGTPIAGREHPDLENQAGLYLNTLAIRTQLKEKSHFASILNQEKETLLEAYQHQNYPFDELIGNLNLKRDM
SRSALFDVMVVLQNQSQLQNLSSGDALTGLQIKNYEFKNNTSQFDVSFVFVEREEGLSLTIQYNTDLYDSLLIKRISAHL
ENLMTQALENPSLAVEELSYITPDEKLQVTETFNATAAEYSRDKTIIDKFEEQVLKTPDQTAVVFEETELSYQSLNALSN
QLGGYLRKHYDIQPDDLIGIKLERSERMMVAVLGILKSGGAYVPIDLAYPQSRIEYIEKDSSSKLIIDEKVLEAFYKEKD
EYSTLNIVKNNTPSNLAYVIYTSGTTGNPKGVMVENRNAATLIDWSKEEYAHSVFDIVYAVTSYCFDLSVYEFFFTLTTG
KTLRVLKNALDIETYINNDKNVLLNTVPSVVRKLLEDKVSLKNINVLNMAGEILPTDIIDKLPLEIMEVRNLYGPSEDTT
YSTSYLITSKGNRTISVGRPISNTQAWILNESLLPVPVGIAGKLYLSGEGVTRGYLNKPELTAEKFVNNPFVQGGVMYDT
GDLAYWLPDGNIEFLGRKDHQVKIRGFRIELGEIETAVSNYSSTVKQVVVDTKEIESTQVLAAYYTASENINKGELRKHL
QSVLPEFMVPGYFIQLENMPLTPNGKIDRKALPEVSEKHIIKKEYVAPKTKIEKSLVTIWQEVLKVDRIGITDNFFELGG
HSLMAGQLINRVNKQFDVSINIKEIFMSPTIEILALNIENTKWIEETVLEDSTAKILI

Sequences:

>Translated_2138_residues
MKNDILNKLLSLGVQLKIIDGNLKVNAPKGVLTKELLEEIKEYKAYLISLISFNTSIPKTEIKENYALTPTQYFMWFTHE
HLGGKRAYNITSTLKLKGKLNEFLLEKAFQKVITRHESLRTVFKKDENDQVQQHILSSDEVHFKLQKAALQHFSVEQLHN
RIKLEYLNTFDLEKGPLLNGTLLKTSEEEHILVFVLHHIIGDGWSLQLLTREIMLVYNSLASAEEVQLQELSIQYKDYSE
WLNKKLISDEYNQKLEFWKEQFKTKSPALELIMNKRPTVKTYNGRIYNHEFSKQFLGELNAFAKEQQMTLFMLLMGSLNG
LFYKYTGQTDITLGTTAAGREHTDLEHQIGLYSNALAIRTKFHKEDSFLELMQKQKNTLIKAYENKEYPFTALVNHLKPA
KDQSRSALFDIMVLLQNHQGLEINDQKGINGITASEYNEIERGVSQLDISFVFVEKEHGLSLSVEYNTDIYNQDFITALL
SHFEEFVKSGLQNPNQPINDVEIVTAAEKNKILTEFNQDNVSSEVSLTVIDLIKSAAAENPNKTALVYQEEEISYRTLDI
YSSKLANYLQQNRNVKKGDFVGIGLQRNSWSIITILAVLKTGAVYVPIDPDYPEDRRNYIEKDSGCKFTITAAVLEEFKN
ISDRFIGEYKAEVSPGDLAYIIYTSGSTGNPKGVQITHTSLTDYAVTFKNYFQLTLHDSIVQQASISFDTSIEEIFPILV
SGGSMVIYDGKGDFETLFRLCEKHNVTVLSTNPYALQYLNAAYDQFDLQIRILISGGDVLQPDYIHNLWNHISVYNTYGP
TESTVCATYYHVNEKLNAVSIGKPIANRQVYIIEPESSQLAPVGIIGELCISGKGLSAGYLNQPELTAEKFVQNPFIKGE
RMYRTGDLAYWLPDGNIEYIGRIDSQVKIRGFRIELGEIETALLQYSQNVRQAVAAVKEINGEKVLAAYYVSTQEIDKSE
IRSYLQGKLPEYMVPGFYIALDVLPLTPNGKTDRKALPEISGEDLIRKEYAAPRNAAEQNLAQIWQEVLGVDQVGITDNF
FELGGHSLVAAQVINRIQKQLNKKVSFKDFFSNPTIEALSARLSDAGYVSITPAPIQESYPLTASQNRLWLLSQLDGGSL
AYNIPFAFELSGALDKDNFQASLKKVIERHEILRTYFKSDESGVVRQHILQADLVNFKLIEEDFTQIDNQQKSVSNYLQQ
QNHIAFDLEKAPLLRAGLVKLEEQKHIFFLTMHHIIGDGWSLELLISEVVKIYNALNEGKDADLPVLNIQYKDYAVWLSN
ELEQEKHLVSKEFWMNQFTGEIPVLDLPSFNKRPLSQSYKGDSVSHTFSQTFLYKLKSYSKTQDATLFMTLMAGVKTLLY
RYTGQNDLVIGTPIAGREHPDLENQAGLYLNTLAIRTQLKEKSHFASILNQEKETLLEAYQHQNYPFDELIGNLNLKRDM
SRSALFDVMVVLQNQSQLQNLSSGDALTGLQIKNYEFKNNTSQFDVSFVFVEREEGLSLTIQYNTDLYDSLLIKRISAHL
ENLMTQALENPSLAVEELSYITPDEKLQVTETFNATAAEYSRDKTIIDKFEEQVLKTPDQTAVVFEETELSYQSLNALSN
QLGGYLRKHYDIQPDDLIGIKLERSERMMVAVLGILKSGGAYVPIDLAYPQSRIEYIEKDSSSKLIIDEKVLEAFYKEKD
EYSTLNIVKNNTPSNLAYVIYTSGTTGNPKGVMVENRNAATLIDWSKEEYAHSVFDIVYAVTSYCFDLSVYEFFFTLTTG
KTLRVLKNALDIETYINNDKNVLLNTVPSVVRKLLEDKVSLKNINVLNMAGEILPTDIIDKLPLEIMEVRNLYGPSEDTT
YSTSYLITSKGNRTISVGRPISNTQAWILNESLLPVPVGIAGKLYLSGEGVTRGYLNKPELTAEKFVNNPFVQGGVMYDT
GDLAYWLPDGNIEFLGRKDHQVKIRGFRIELGEIETAVSNYSSTVKQVVVDTKEIESTQVLAAYYTASENINKGELRKHL
QSVLPEFMVPGYFIQLENMPLTPNGKIDRKALPEVSEKHIIKKEYVAPKTKIEKSLVTIWQEVLKVDRIGITDNFFELGG
HSLMAGQLINRVNKQFDVSINIKEIFMSPTIEILALNIENTKWIEETVLEDSTAKILI
>Mature_2138_residues
MKNDILNKLLSLGVQLKIIDGNLKVNAPKGVLTKELLEEIKEYKAYLISLISFNTSIPKTEIKENYALTPTQYFMWFTHE
HLGGKRAYNITSTLKLKGKLNEFLLEKAFQKVITRHESLRTVFKKDENDQVQQHILSSDEVHFKLQKAALQHFSVEQLHN
RIKLEYLNTFDLEKGPLLNGTLLKTSEEEHILVFVLHHIIGDGWSLQLLTREIMLVYNSLASAEEVQLQELSIQYKDYSE
WLNKKLISDEYNQKLEFWKEQFKTKSPALELIMNKRPTVKTYNGRIYNHEFSKQFLGELNAFAKEQQMTLFMLLMGSLNG
LFYKYTGQTDITLGTTAAGREHTDLEHQIGLYSNALAIRTKFHKEDSFLELMQKQKNTLIKAYENKEYPFTALVNHLKPA
KDQSRSALFDIMVLLQNHQGLEINDQKGINGITASEYNEIERGVSQLDISFVFVEKEHGLSLSVEYNTDIYNQDFITALL
SHFEEFVKSGLQNPNQPINDVEIVTAAEKNKILTEFNQDNVSSEVSLTVIDLIKSAAAENPNKTALVYQEEEISYRTLDI
YSSKLANYLQQNRNVKKGDFVGIGLQRNSWSIITILAVLKTGAVYVPIDPDYPEDRRNYIEKDSGCKFTITAAVLEEFKN
ISDRFIGEYKAEVSPGDLAYIIYTSGSTGNPKGVQITHTSLTDYAVTFKNYFQLTLHDSIVQQASISFDTSIEEIFPILV
SGGSMVIYDGKGDFETLFRLCEKHNVTVLSTNPYALQYLNAAYDQFDLQIRILISGGDVLQPDYIHNLWNHISVYNTYGP
TESTVCATYYHVNEKLNAVSIGKPIANRQVYIIEPESSQLAPVGIIGELCISGKGLSAGYLNQPELTAEKFVQNPFIKGE
RMYRTGDLAYWLPDGNIEYIGRIDSQVKIRGFRIELGEIETALLQYSQNVRQAVAAVKEINGEKVLAAYYVSTQEIDKSE
IRSYLQGKLPEYMVPGFYIALDVLPLTPNGKTDRKALPEISGEDLIRKEYAAPRNAAEQNLAQIWQEVLGVDQVGITDNF
FELGGHSLVAAQVINRIQKQLNKKVSFKDFFSNPTIEALSARLSDAGYVSITPAPIQESYPLTASQNRLWLLSQLDGGSL
AYNIPFAFELSGALDKDNFQASLKKVIERHEILRTYFKSDESGVVRQHILQADLVNFKLIEEDFTQIDNQQKSVSNYLQQ
QNHIAFDLEKAPLLRAGLVKLEEQKHIFFLTMHHIIGDGWSLELLISEVVKIYNALNEGKDADLPVLNIQYKDYAVWLSN
ELEQEKHLVSKEFWMNQFTGEIPVLDLPSFNKRPLSQSYKGDSVSHTFSQTFLYKLKSYSKTQDATLFMTLMAGVKTLLY
RYTGQNDLVIGTPIAGREHPDLENQAGLYLNTLAIRTQLKEKSHFASILNQEKETLLEAYQHQNYPFDELIGNLNLKRDM
SRSALFDVMVVLQNQSQLQNLSSGDALTGLQIKNYEFKNNTSQFDVSFVFVEREEGLSLTIQYNTDLYDSLLIKRISAHL
ENLMTQALENPSLAVEELSYITPDEKLQVTETFNATAAEYSRDKTIIDKFEEQVLKTPDQTAVVFEETELSYQSLNALSN
QLGGYLRKHYDIQPDDLIGIKLERSERMMVAVLGILKSGGAYVPIDLAYPQSRIEYIEKDSSSKLIIDEKVLEAFYKEKD
EYSTLNIVKNNTPSNLAYVIYTSGTTGNPKGVMVENRNAATLIDWSKEEYAHSVFDIVYAVTSYCFDLSVYEFFFTLTTG
KTLRVLKNALDIETYINNDKNVLLNTVPSVVRKLLEDKVSLKNINVLNMAGEILPTDIIDKLPLEIMEVRNLYGPSEDTT
YSTSYLITSKGNRTISVGRPISNTQAWILNESLLPVPVGIAGKLYLSGEGVTRGYLNKPELTAEKFVNNPFVQGGVMYDT
GDLAYWLPDGNIEFLGRKDHQVKIRGFRIELGEIETAVSNYSSTVKQVVVDTKEIESTQVLAAYYTASENINKGELRKHL
QSVLPEFMVPGYFIQLENMPLTPNGKIDRKALPEVSEKHIIKKEYVAPKTKIEKSLVTIWQEVLKVDRIGITDNFFELGG
HSLMAGQLINRVNKQFDVSINIKEIFMSPTIEILALNIENTKWIEETVLEDSTAKILI

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=628, Percent_Identity=24.3630573248408, Blast_Score=129, Evalue=3e-29,
Organism=Homo sapiens, GI42544132, Length=517, Percent_Identity=23.7911025145068, Blast_Score=97, Evalue=2e-19,
Organism=Homo sapiens, GI156151445, Length=557, Percent_Identity=22.8007181328546, Blast_Score=96, Evalue=5e-19,
Organism=Homo sapiens, GI122937307, Length=524, Percent_Identity=24.236641221374, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI28416953, Length=537, Percent_Identity=24.2085661080074, Blast_Score=86, Evalue=6e-16,
Organism=Homo sapiens, GI38505220, Length=496, Percent_Identity=24.1935483870968, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI58082049, Length=513, Percent_Identity=22.0272904483431, Blast_Score=77, Evalue=3e-13,
Organism=Homo sapiens, GI157311624, Length=513, Percent_Identity=21.8323586744639, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI157311622, Length=513, Percent_Identity=21.8323586744639, Blast_Score=74, Evalue=1e-12,
Organism=Escherichia coli, GI1786801, Length=1114, Percent_Identity=25.1346499102334, Blast_Score=305, Evalue=3e-83,
Organism=Escherichia coli, GI1788107, Length=555, Percent_Identity=22.1621621621622, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1790505, Length=546, Percent_Identity=25.8241758241758, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1786810, Length=500, Percent_Identity=22.4, Blast_Score=95, Evalue=6e-20,
Organism=Escherichia coli, GI145693145, Length=528, Percent_Identity=24.0530303030303, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=1134, Percent_Identity=24.6031746031746, Blast_Score=216, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17556356, Length=566, Percent_Identity=28.0918727915194, Blast_Score=177, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI32564420, Length=509, Percent_Identity=23.3791748526523, Blast_Score=95, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32564422, Length=509, Percent_Identity=23.3791748526523, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32563687, Length=472, Percent_Identity=23.9406779661017, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559526, Length=376, Percent_Identity=23.4042553191489, Blast_Score=89, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=334, Percent_Identity=23.3532934131737, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17558820, Length=483, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17557194, Length=536, Percent_Identity=21.2686567164179, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531443, Length=507, Percent_Identity=21.8934911242604, Blast_Score=75, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538037, Length=374, Percent_Identity=21.6577540106952, Blast_Score=75, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71985884, Length=367, Percent_Identity=22.8882833787466, Blast_Score=74, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560308, Length=375, Percent_Identity=22.6666666666667, Blast_Score=69, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553312, Length=218, Percent_Identity=29.8165137614679, Blast_Score=68, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=751, Percent_Identity=26.6311584553928, Blast_Score=231, Evalue=8e-61,
Organism=Saccharomyces cerevisiae, GI6319699, Length=351, Percent_Identity=26.4957264957265, Blast_Score=95, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323182, Length=396, Percent_Identity=24.4949494949495, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24648676, Length=597, Percent_Identity=27.3031825795645, Blast_Score=167, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24581924, Length=371, Percent_Identity=26.1455525606469, Blast_Score=93, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859661, Length=519, Percent_Identity=23.6994219653179, Blast_Score=86, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356441, Length=350, Percent_Identity=26.5714285714286, Blast_Score=83, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355181, Length=516, Percent_Identity=23.4496124031008, Blast_Score=83, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582852, Length=373, Percent_Identity=24.9329758713137, Blast_Score=77, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 242657; Mature: 242657

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNDILNKLLSLGVQLKIIDGNLKVNAPKGVLTKELLEEIKEYKAYLISLISFNTSIPKT
CCHHHHHHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EIKENYALTPTQYFMWFTHEHLGGKRAYNITSTLKLKGKLNEFLLEKAFQKVITRHESLR
HHCCCCCCCCHHEEEEEEHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
TVFKKDENDQVQQHILSSDEVHFKLQKAALQHFSVEQLHNRIKLEYLNTFDLEKGPLLNG
HHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCCEEEEEECEECCCCCCCCCC
TLLKTSEEEHILVFVLHHIIGDGWSLQLLTREIMLVYNSLASAEEVQLQELSIQYKDYSE
EEEECCCCCEEHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHEEEEHHHHH
WLNKKLISDEYNQKLEFWKEQFKTKSPALELIMNKRPTVKTYNGRIYNHEFSKQFLGELN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECCEEECCHHHHHHHHHHH
AFAKEQQMTLFMLLMGSLNGLFYKYTGQTDITLGTTAAGREHTDLEHQIGLYSNALAIRT
HHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHCHHCCEEEEEE
KFHKEDSFLELMQKQKNTLIKAYENKEYPFTALVNHLKPAKDQSRSALFDIMVLLQNHQG
ECCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
LEINDQKGINGITASEYNEIERGVSQLDISFVFVEKEHGLSLSVEYNTDIYNQDFITALL
CEECCCCCCCCCCHHHHHHHHCCHHHEEEEEEEEEECCCEEEEEEECCCCCCHHHHHHHH
SHFEEFVKSGLQNPNQPINDVEIVTAAEKNKILTEFNQDNVSSEVSLTVIDLIKSAAAEN
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
PNKTALVYQEEEISYRTLDIYSSKLANYLQQNRNVKKGDFVGIGLQRNSWSIITILAVLK
CCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHH
TGAVYVPIDPDYPEDRRNYIEKDSGCKFTITAAVLEEFKNISDRFIGEYKAEVSPGDLAY
CCCEEEECCCCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IIYTSGSTGNPKGVQITHTSLTDYAVTFKNYFQLTLHDSIVQQASISFDTSIEEIFPILV
EEEECCCCCCCCCEEEEECCCCHHHEEEEHHEEEEEHHHHHHHHCCCCCCCHHHHHHHHC
SGGSMVIYDGKGDFETLFRLCEKHNVTVLSTNPYALQYLNAAYDQFDLQIRILISGGDVL
CCCCEEEECCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCEEEEEEEECCCCC
QPDYIHNLWNHISVYNTYGPTESTVCATYYHVNEKLNAVSIGKPIANRQVYIIEPESSQL
CCHHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCC
APVGIIGELCISGKGLSAGYLNQPELTAEKFVQNPFIKGERMYRTGDLAYWLPDGNIEYI
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCEEEECCCCCEEEE
GRIDSQVKIRGFRIELGEIETALLQYSQNVRQAVAAVKEINGEKVLAAYYVSTQEIDKSE
EECCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHCCHHH
IRSYLQGKLPEYMVPGFYIALDVLPLTPNGKTDRKALPEISGEDLIRKEYAAPRNAAEQN
HHHHHHCCCCCHHCCCEEEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHCCCCCHHHHH
LAQIWQEVLGVDQVGITDNFFELGGHSLVAAQVINRIQKQLNKKVSFKDFFSNPTIEALS
HHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHH
ARLSDAGYVSITPAPIQESYPLTASQNRLWLLSQLDGGSLAYNIPFAFELSGALDKDNFQ
HHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCEEEEECCCCCCCHHH
ASLKKVIERHEILRTYFKSDESGVVRQHILQADLVNFKLIEEDFTQIDNQQKSVSNYLQQ
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHCCHHHHHHHHHHH
QNHIAFDLEKAPLLRAGLVKLEEQKHIFFLTMHHIIGDGWSLELLISEVVKIYNALNEGK
CCCEEEECCCCCHHHHHHHHCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCC
DADLPVLNIQYKDYAVWLSNELEQEKHLVSKEFWMNQFTGEIPVLDLPSFNKRPLSQSYK
CCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCC
GDSVSHTFSQTFLYKLKSYSKTQDATLFMTLMAGVKTLLYRYTGQNDLVIGTPIAGREHP
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
DLENQAGLYLNTLAIRTQLKEKSHFASILNQEKETLLEAYQHQNYPFDELIGNLNLKRDM
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHH
SRSALFDVMVVLQNQSQLQNLSSGDALTGLQIKNYEFKNNTSQFDVSFVFVEREEGLSLT
HHHHHHHHHHHHCCHHHHHCCCCCCCEECEEEECEEECCCCCEEEEEEEEEEECCCCEEE
IQYNTDLYDSLLIKRISAHLENLMTQALENPSLAVEELSYITPDEKLQVTETFNATAAEY
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHH
SRDKTIIDKFEEQVLKTPDQTAVVFEETELSYQSLNALSNQLGGYLRKHYDIQPDDLIGI
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
KLERSERMMVAVLGILKSGGAYVPIDLAYPQSRIEYIEKDSSSKLIIDEKVLEAFYKEKD
EECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCEEEEHHHHHHHHHHCCC
EYSTLNIVKNNTPSNLAYVIYTSGTTGNPKGVMVENRNAATLIDWSKEEYAHSVFDIVYA
CCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHH
VTSYCFDLSVYEFFFTLTTGKTLRVLKNALDIETYINNDKNVLLNTVPSVVRKLLEDKVS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
LKNINVLNMAGEILPTDIIDKLPLEIMEVRNLYGPSEDTTYSTSYLITSKGNRTISVGRP
HCCCEEEECCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEEECCC
ISNTQAWILNESLLPVPVGIAGKLYLSGEGVTRGYLNKPELTAEKFVNNPFVQGGVMYDT
CCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEC
GDLAYWLPDGNIEFLGRKDHQVKIRGFRIELGEIETAVSNYSSTVKQVVVDTKEIESTQV
CCEEEEECCCCEEEEECCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LAAYYTASENINKGELRKHLQSVLPEFMVPGYFIQLENMPLTPNGKIDRKALPEVSEKHI
EEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHCCCHHHHHH
IKKEYVAPKTKIEKSLVTIWQEVLKVDRIGITDNFFELGGHSLMAGQLINRVNKQFDVSI
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCEEEEEE
NIKEIFMSPTIEILALNIENTKWIEETVLEDSTAKILI
EHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEC
>Mature Secondary Structure
MKNDILNKLLSLGVQLKIIDGNLKVNAPKGVLTKELLEEIKEYKAYLISLISFNTSIPKT
CCHHHHHHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EIKENYALTPTQYFMWFTHEHLGGKRAYNITSTLKLKGKLNEFLLEKAFQKVITRHESLR
HHCCCCCCCCHHEEEEEEHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
TVFKKDENDQVQQHILSSDEVHFKLQKAALQHFSVEQLHNRIKLEYLNTFDLEKGPLLNG
HHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCCEEEEEECEECCCCCCCCCC
TLLKTSEEEHILVFVLHHIIGDGWSLQLLTREIMLVYNSLASAEEVQLQELSIQYKDYSE
EEEECCCCCEEHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHEEEEHHHHH
WLNKKLISDEYNQKLEFWKEQFKTKSPALELIMNKRPTVKTYNGRIYNHEFSKQFLGELN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEECCEEECCHHHHHHHHHHH
AFAKEQQMTLFMLLMGSLNGLFYKYTGQTDITLGTTAAGREHTDLEHQIGLYSNALAIRT
HHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHCHHCCEEEEEE
KFHKEDSFLELMQKQKNTLIKAYENKEYPFTALVNHLKPAKDQSRSALFDIMVLLQNHQG
ECCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
LEINDQKGINGITASEYNEIERGVSQLDISFVFVEKEHGLSLSVEYNTDIYNQDFITALL
CEECCCCCCCCCCHHHHHHHHCCHHHEEEEEEEEEECCCEEEEEEECCCCCCHHHHHHHH
SHFEEFVKSGLQNPNQPINDVEIVTAAEKNKILTEFNQDNVSSEVSLTVIDLIKSAAAEN
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCC
PNKTALVYQEEEISYRTLDIYSSKLANYLQQNRNVKKGDFVGIGLQRNSWSIITILAVLK
CCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHH
TGAVYVPIDPDYPEDRRNYIEKDSGCKFTITAAVLEEFKNISDRFIGEYKAEVSPGDLAY
CCCEEEECCCCCCHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
IIYTSGSTGNPKGVQITHTSLTDYAVTFKNYFQLTLHDSIVQQASISFDTSIEEIFPILV
EEEECCCCCCCCCEEEEECCCCHHHEEEEHHEEEEEHHHHHHHHCCCCCCCHHHHHHHHC
SGGSMVIYDGKGDFETLFRLCEKHNVTVLSTNPYALQYLNAAYDQFDLQIRILISGGDVL
CCCCEEEECCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCEEEEEEEECCCCC
QPDYIHNLWNHISVYNTYGPTESTVCATYYHVNEKLNAVSIGKPIANRQVYIIEPESSQL
CCHHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCCCEEECCCCCCCCEEEEECCCCCCC
APVGIIGELCISGKGLSAGYLNQPELTAEKFVQNPFIKGERMYRTGDLAYWLPDGNIEYI
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCEEEECCCCCEEEE
GRIDSQVKIRGFRIELGEIETALLQYSQNVRQAVAAVKEINGEKVLAAYYVSTQEIDKSE
EECCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHCCHHH
IRSYLQGKLPEYMVPGFYIALDVLPLTPNGKTDRKALPEISGEDLIRKEYAAPRNAAEQN
HHHHHHCCCCCHHCCCEEEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHCCCCCHHHHH
LAQIWQEVLGVDQVGITDNFFELGGHSLVAAQVINRIQKQLNKKVSFKDFFSNPTIEALS
HHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHH
ARLSDAGYVSITPAPIQESYPLTASQNRLWLLSQLDGGSLAYNIPFAFELSGALDKDNFQ
HHCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCEEEEECCCCCCCHHH
ASLKKVIERHEILRTYFKSDESGVVRQHILQADLVNFKLIEEDFTQIDNQQKSVSNYLQQ
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHCCHHHHHHHHHHH
QNHIAFDLEKAPLLRAGLVKLEEQKHIFFLTMHHIIGDGWSLELLISEVVKIYNALNEGK
CCCEEEECCCCCHHHHHHHHCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCC
DADLPVLNIQYKDYAVWLSNELEQEKHLVSKEFWMNQFTGEIPVLDLPSFNKRPLSQSYK
CCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCC
GDSVSHTFSQTFLYKLKSYSKTQDATLFMTLMAGVKTLLYRYTGQNDLVIGTPIAGREHP
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
DLENQAGLYLNTLAIRTQLKEKSHFASILNQEKETLLEAYQHQNYPFDELIGNLNLKRDM
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHH
SRSALFDVMVVLQNQSQLQNLSSGDALTGLQIKNYEFKNNTSQFDVSFVFVEREEGLSLT
HHHHHHHHHHHHCCHHHHHCCCCCCCEECEEEECEEECCCCCEEEEEEEEEEECCCCEEE
IQYNTDLYDSLLIKRISAHLENLMTQALENPSLAVEELSYITPDEKLQVTETFNATAAEY
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHH
SRDKTIIDKFEEQVLKTPDQTAVVFEETELSYQSLNALSNQLGGYLRKHYDIQPDDLIGI
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
KLERSERMMVAVLGILKSGGAYVPIDLAYPQSRIEYIEKDSSSKLIIDEKVLEAFYKEKD
EECCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCEEEEHHHHHHHHHHCCC
EYSTLNIVKNNTPSNLAYVIYTSGTTGNPKGVMVENRNAATLIDWSKEEYAHSVFDIVYA
CCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHH
VTSYCFDLSVYEFFFTLTTGKTLRVLKNALDIETYINNDKNVLLNTVPSVVRKLLEDKVS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHH
LKNINVLNMAGEILPTDIIDKLPLEIMEVRNLYGPSEDTTYSTSYLITSKGNRTISVGRP
HCCCEEEECCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEEEEECCCEEEEECCC
ISNTQAWILNESLLPVPVGIAGKLYLSGEGVTRGYLNKPELTAEKFVNNPFVQGGVMYDT
CCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEC
GDLAYWLPDGNIEFLGRKDHQVKIRGFRIELGEIETAVSNYSSTVKQVVVDTKEIESTQV
CCEEEEECCCCEEEEECCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LAAYYTASENINKGELRKHLQSVLPEFMVPGYFIQLENMPLTPNGKIDRKALPEVSEKHI
EEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHCCCHHHHHH
IKKEYVAPKTKIEKSLVTIWQEVLKVDRIGITDNFFELGGHSLMAGQLINRVNKQFDVSI
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCEEEEEE
NIKEIFMSPTIEILALNIENTKWIEETVLEDSTAKILI
EHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]