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The map label for this gene is exsA [H]

Identifier: 146299751

GI number: 146299751

Start: 2323655

End: 2324515

Strand: Direct

Name: exsA [H]

Synonym: Fjoh_1991

Alternate gene names: 146299751

Gene position: 2323655-2324515 (Clockwise)

Preceding gene: 146299750

Following gene: 146299752

Centisome position: 38.11

GC content: 30.31

Gene sequence:

>861_bases
ATGCATACCATTACACTTCCCGATGAAATGAATTTAGAAAAAACACAGCAAATACATGTTGTGGATTACAGAAGTTCTAA
AGATGTTTCGAAACAGCAGATTATTCTAAACCAGAATATAATTAGTTTTCTTATTGAAGGGACAAAAGAAGCTGTTTTCG
ATAATGCGTCCTTGTCTATAGATGCTTCTAAGTTTTTAATAATGAGATCAGGAAATTGTTTAATGACAGAAAAAAGGATT
TCGGAAGCCTCAAATTATAGAAGCGTACTCTTGTTTTTTTCTAACGAAATGATTCATAATTTCATTAGAAAAATGGAAAT
AAATGATTTTGAATCAGTTGACACCAAGTCTGTTTATGCTTTTGATTATGATGATTTCATACAAAGATTTGTACACAGCT
TAGTAGATATTTCTAAACTTTCGGGAGAAATAAAATCCAAATTATTAGAAGTGAAGCTGGAAGAAATCATGCTTTATCTT
ACCGAAAAGTATGGAACAAAGTTTCTGTACTCCTTAACTGTAAATAGTAATAATGCTACGCAAAAGTTTATTCAGGTAAT
TGAAAACAGTCATTTAAGTAAACTCACTTTAAAAGAACTGGCATTTTTATGTAATATGAGTATTTCAACATTCAAAAGAG
AATTTGAAAAACATTACGCCGAATCTCCAATAAAATGGTTTCAAAACAAAAGACTGGAGTTTGCTCATTATTTATTGCAG
CAAGAACAAAAAAATCCATCAGAAATATATTTTGAAGTTGGTTACGAAAACCTGTCCAGTTTTACGCAGGCTTATAAATT
AAAATACGGCGTAACGCCAAAACAAAATCAGAAAAACTGGACTTTTAGCAACAGTTTTTGA

Upstream 100 bases:

>100_bases
AAAAATGATGATGCCAAAGAAATTACCTTTTTAAATACAGAAGTCCTTGCCAGAGAGTCATCTAGTAAAGAGTAAATGAG
AAAGAATTAAATTGTCATTT

Downstream 100 bases:

>100_bases
TCCTTTCCCTAAAGTTTCGCTGGCATAGCAGAATCTAAATTTGCTTTAAATTTTAAAACCAAGTAAAATGAAAAAGCTAA
ATTTAATTTTGGTGTTGTCT

Product: helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MHTITLPDEMNLEKTQQIHVVDYRSSKDVSKQQIILNQNIISFLIEGTKEAVFDNASLSIDASKFLIMRSGNCLMTEKRI
SEASNYRSVLLFFSNEMIHNFIRKMEINDFESVDTKSVYAFDYDDFIQRFVHSLVDISKLSGEIKSKLLEVKLEEIMLYL
TEKYGTKFLYSLTVNSNNATQKFIQVIENSHLSKLTLKELAFLCNMSISTFKREFEKHYAESPIKWFQNKRLEFAHYLLQ
QEQKNPSEIYFEVGYENLSSFTQAYKLKYGVTPKQNQKNWTFSNSF

Sequences:

>Translated_286_residues
MHTITLPDEMNLEKTQQIHVVDYRSSKDVSKQQIILNQNIISFLIEGTKEAVFDNASLSIDASKFLIMRSGNCLMTEKRI
SEASNYRSVLLFFSNEMIHNFIRKMEINDFESVDTKSVYAFDYDDFIQRFVHSLVDISKLSGEIKSKLLEVKLEEIMLYL
TEKYGTKFLYSLTVNSNNATQKFIQVIENSHLSKLTLKELAFLCNMSISTFKREFEKHYAESPIKWFQNKRLEFAHYLLQ
QEQKNPSEIYFEVGYENLSSFTQAYKLKYGVTPKQNQKNWTFSNSF
>Mature_286_residues
MHTITLPDEMNLEKTQQIHVVDYRSSKDVSKQQIILNQNIISFLIEGTKEAVFDNASLSIDASKFLIMRSGNCLMTEKRI
SEASNYRSVLLFFSNEMIHNFIRKMEINDFESVDTKSVYAFDYDDFIQRFVHSLVDISKLSGEIKSKLLEVKLEEIMLYL
TEKYGTKFLYSLTVNSNNATQKFIQVIENSHLSKLTLKELAFLCNMSISTFKREFEKHYAESPIKWFQNKRLEFAHYLLQ
QEQKNPSEIYFEVGYENLSSFTQAYKLKYGVTPKQNQKNWTFSNSF

Specific function: Appears to be required for induction of exoenzyme S synthesis above a low basal level [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082197, Length=126, Percent_Identity=29.3650793650794, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33586; Mature: 33586

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTITLPDEMNLEKTQQIHVVDYRSSKDVSKQQIILNQNIISFLIEGTKEAVFDNASLSI
CCEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCEEE
DASKFLIMRSGNCLMTEKRISEASNYRSVLLFFSNEMIHNFIRKMEINDFESVDTKSVYA
CCCEEEEEECCCEEEEHHHHHHHHCHHEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEE
FDYDDFIQRFVHSLVDISKLSGEIKSKLLEVKLEEIMLYLTEKYGTKFLYSLTVNSNNAT
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHH
QKFIQVIENSHLSKLTLKELAFLCNMSISTFKREFEKHYAESPIKWFQNKRLEFAHYLLQ
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHH
QEQKNPSEIYFEVGYENLSSFTQAYKLKYGVTPKQNQKNWTFSNSF
HHCCCCCCEEEEECHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHTITLPDEMNLEKTQQIHVVDYRSSKDVSKQQIILNQNIISFLIEGTKEAVFDNASLSI
CCEECCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCEEE
DASKFLIMRSGNCLMTEKRISEASNYRSVLLFFSNEMIHNFIRKMEINDFESVDTKSVYA
CCCEEEEEECCCEEEEHHHHHHHHCHHEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEEE
FDYDDFIQRFVHSLVDISKLSGEIKSKLLEVKLEEIMLYLTEKYGTKFLYSLTVNSNNAT
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHH
QKFIQVIENSHLSKLTLKELAFLCNMSISTFKREFEKHYAESPIKWFQNKRLEFAHYLLQ
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHH
QEQKNPSEIYFEVGYENLSSFTQAYKLKYGVTPKQNQKNWTFSNSF
HHCCCCCCEEEEECHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655713; 10984043 [H]