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The map label for this gene is acdA [H]

Identifier: 146299692

GI number: 146299692

Start: 2235611

End: 2236753

Strand: Direct

Name: acdA [H]

Synonym: Fjoh_1932

Alternate gene names: 146299692

Gene position: 2235611-2236753 (Clockwise)

Preceding gene: 146299691

Following gene: 146299693

Centisome position: 36.67

GC content: 36.92

Gene sequence:

>1143_bases
ATGAATTTTGAATATAACGAAACGCAGTCAATGATTGCGCAATCTATAAAAGACTTTGCTGAAAAGAATATAAAACCTTA
TATAATGGAGTGGGATGAGGCGCAGATTTTTCCTGTCGACTTGTTTAAGAAATTAGGTGAAATGGGATTTATGGGGGTTT
TAGTACCTGAAGAATATGGAGGTTCAGGATTGGGTTATCACGAATATATTACAGTAGTTGAAGAAATCTCAAAAGTTGAT
CCTTCAATAGGATTGTCTGTAGCTGCGCATAATTCACTTTGTACAAATCATATTCTAACATTTGGGAACGAAGAACAAAA
GAAAAAATATCTGCCAAAACTAGCAACGGCTGAATTTATTGGAGCTTGGGGACTTACAGAGCATAATACAGGCTCTGATG
CTGGAGGAATGAATACAACAGCTGTTAAAGATGGAGATTTTTGGATTATTAACGGAGCTAAAAACTTTATTACACACGCT
ATATCTGGAGATGTAGCTGTTGTAATTGTTAGAACTGGAGAAAAAGGCGACTCAAAAGGAATGACAGCTTTTGTATTAGA
GAAAGGTATGGCAGGTTTTTCTTCGGGTAAAAAAGAGAATAAGTTGGGAATGCGCGCGAGTGAAACGGCTGAATTGGTTT
TTGACGGCTGTCGTGTGCCAGATGCAAATAGATTAGGAGAAGTCGGTCAGGGATTTGTTCAGGCAATGAAAATTTTAGAT
GGAGGCCGAATTTCAATTGGAGCCTTATCATTAGGAATTTCAAAAGGAGCTTACGAAGCAGCATTGAAATATTCAAAAGA
AAGATATCAGTTTGGTCAGCCAATCAGTAATTTTCAGGGAATTTCTTTTAAATTGGCTGATATGGCTACAGAAATTGAAG
CCTCAGAACTGCTTCTGCATAAAGCTGCTTATTTAAAACAGCAACATAAACCAGTAACAACTTCGGGAGCTATGGCAAAA
ATGTACGCATCAGAAGCTTGTGTGAAAATCGCAAATGAAGCAGTTCAGATACATGGAGGTTATGGTTATACAAAAGATTT
TCCGGTAGAGAAATTTTACAGAGACTCTAAATTGTGTACTATTGGAGAAGGAACTACCGAAATTCAGAAACTGGTTATTT
CGAGAAACTTATTGAAAGAATAG

Upstream 100 bases:

>100_bases
AAATTTTAATAATATTGAGGATTTGTCAAAAATTAAAGGTTTTCCTGTTGAAAAAGCAAAAATAATTAGTTTATATTTGG
AGTTCTAAAAAATTAGTAAA

Downstream 100 bases:

>100_bases
ATTTTGTAAAATAATTTACATTTTATAATTCATAATTCATAATTAATTTTTACATTTGCAGCCTTAACGAGAGGAGGTGT
CTATATTATGTTAATTATAC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNFEYNETQSMIAQSIKDFAEKNIKPYIMEWDEAQIFPVDLFKKLGEMGFMGVLVPEEYGGSGLGYHEYITVVEEISKVD
PSIGLSVAAHNSLCTNHILTFGNEEQKKKYLPKLATAEFIGAWGLTEHNTGSDAGGMNTTAVKDGDFWIINGAKNFITHA
ISGDVAVVIVRTGEKGDSKGMTAFVLEKGMAGFSSGKKENKLGMRASETAELVFDGCRVPDANRLGEVGQGFVQAMKILD
GGRISIGALSLGISKGAYEAALKYSKERYQFGQPISNFQGISFKLADMATEIEASELLLHKAAYLKQQHKPVTTSGAMAK
MYASEACVKIANEAVQIHGGYGYTKDFPVEKFYRDSKLCTIGEGTTEIQKLVISRNLLKE

Sequences:

>Translated_380_residues
MNFEYNETQSMIAQSIKDFAEKNIKPYIMEWDEAQIFPVDLFKKLGEMGFMGVLVPEEYGGSGLGYHEYITVVEEISKVD
PSIGLSVAAHNSLCTNHILTFGNEEQKKKYLPKLATAEFIGAWGLTEHNTGSDAGGMNTTAVKDGDFWIINGAKNFITHA
ISGDVAVVIVRTGEKGDSKGMTAFVLEKGMAGFSSGKKENKLGMRASETAELVFDGCRVPDANRLGEVGQGFVQAMKILD
GGRISIGALSLGISKGAYEAALKYSKERYQFGQPISNFQGISFKLADMATEIEASELLLHKAAYLKQQHKPVTTSGAMAK
MYASEACVKIANEAVQIHGGYGYTKDFPVEKFYRDSKLCTIGEGTTEIQKLVISRNLLKE
>Mature_380_residues
MNFEYNETQSMIAQSIKDFAEKNIKPYIMEWDEAQIFPVDLFKKLGEMGFMGVLVPEEYGGSGLGYHEYITVVEEISKVD
PSIGLSVAAHNSLCTNHILTFGNEEQKKKYLPKLATAEFIGAWGLTEHNTGSDAGGMNTTAVKDGDFWIINGAKNFITHA
ISGDVAVVIVRTGEKGDSKGMTAFVLEKGMAGFSSGKKENKLGMRASETAELVFDGCRVPDANRLGEVGQGFVQAMKILD
GGRISIGALSLGISKGAYEAALKYSKERYQFGQPISNFQGISFKLADMATEIEASELLLHKAAYLKQQHKPVTTSGAMAK
MYASEACVKIANEAVQIHGGYGYTKDFPVEKFYRDSKLCTIGEGTTEIQKLVISRNLLKE

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=43.6507936507937, Blast_Score=329, Evalue=2e-90,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=40.9574468085106, Blast_Score=304, Evalue=1e-82,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=39.572192513369, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=38.6058981233244, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI226958414, Length=338, Percent_Identity=41.4201183431953, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI21361497, Length=380, Percent_Identity=38.4210526315789, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=34.3915343915344, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=34.4827586206897, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI76496475, Length=382, Percent_Identity=35.8638743455497, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4557235, Length=382, Percent_Identity=35.8638743455497, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=32.7127659574468, Blast_Score=225, Evalue=5e-59,
Organism=Homo sapiens, GI4503943, Length=370, Percent_Identity=31.0810810810811, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI7669494, Length=344, Percent_Identity=31.6860465116279, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI48976061, Length=334, Percent_Identity=24.251497005988, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI211971008, Length=334, Percent_Identity=24.251497005988, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38505218, Length=358, Percent_Identity=24.0223463687151, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI87081958, Length=384, Percent_Identity=31.25, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=27.8215223097113, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI87081702, Length=331, Percent_Identity=25.6797583081571, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=41.3978494623656, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17538396, Length=384, Percent_Identity=39.3229166666667, Blast_Score=283, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=38.6486486486486, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17533517, Length=369, Percent_Identity=37.940379403794, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=37.3368146214099, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71990804, Length=303, Percent_Identity=42.5742574257426, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=33.8582677165354, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=36.4829396325459, Blast_Score=237, Evalue=9e-63,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=33.5078534031414, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=36.6300366300366, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI32563615, Length=253, Percent_Identity=39.5256916996047, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=29.144385026738, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17534353, Length=374, Percent_Identity=28.6096256684492, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=383, Percent_Identity=29.242819843342, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71985192, Length=307, Percent_Identity=35.1791530944625, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17531909, Length=244, Percent_Identity=31.9672131147541, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI86563383, Length=357, Percent_Identity=28.8515406162465, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI86563381, Length=357, Percent_Identity=28.8515406162465, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17531913, Length=206, Percent_Identity=30.5825242718447, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=331, Percent_Identity=25.3776435045317, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=42.9333333333333, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=40, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=40.1069518716578, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=35.3403141361257, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=35.8839050131926, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI281363737, Length=344, Percent_Identity=37.7906976744186, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=30.3896103896104, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24652780, Length=351, Percent_Identity=21.6524216524217, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41474; Mature: 41474

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFEYNETQSMIAQSIKDFAEKNIKPYIMEWDEAQIFPVDLFKKLGEMGFMGVLVPEEYG
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEHHHHHHHHHHCCCEEEECCCCCC
GSGLGYHEYITVVEEISKVDPSIGLSVAAHNSLCTNHILTFGNEEQKKKYLPKLATAEFI
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHEECCCHHHHHHHCCHHHHHHHH
GAWGLTEHNTGSDAGGMNTTAVKDGDFWIINGAKNFITHAISGDVAVVIVRTGEKGDSKG
HCCCCCCCCCCCCCCCCCCCEEECCCEEEECCCHHHHHHHCCCCEEEEEEEECCCCCCCC
MTAFVLEKGMAGFSSGKKENKLGMRASETAELVFDGCRVPDANRLGEVGQGFVQAMKILD
CEEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GGRISIGALSLGISKGAYEAALKYSKERYQFGQPISNFQGISFKLADMATEIEASELLLH
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
KAAYLKQQHKPVTTSGAMAKMYASEACVKIANEAVQIHGGYGYTKDFPVEKFYRDSKLCT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCCEEE
IGEGTTEIQKLVISRNLLKE
ECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFEYNETQSMIAQSIKDFAEKNIKPYIMEWDEAQIFPVDLFKKLGEMGFMGVLVPEEYG
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEHHHHHHHHHHCCCEEEECCCCCC
GSGLGYHEYITVVEEISKVDPSIGLSVAAHNSLCTNHILTFGNEEQKKKYLPKLATAEFI
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHEECCCHHHHHHHCCHHHHHHHH
GAWGLTEHNTGSDAGGMNTTAVKDGDFWIINGAKNFITHAISGDVAVVIVRTGEKGDSKG
HCCCCCCCCCCCCCCCCCCCEEECCCEEEECCCHHHHHHHCCCCEEEEEEEECCCCCCCC
MTAFVLEKGMAGFSSGKKENKLGMRASETAELVFDGCRVPDANRLGEVGQGFVQAMKILD
CEEEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GGRISIGALSLGISKGAYEAALKYSKERYQFGQPISNFQGISFKLADMATEIEASELLLH
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
KAAYLKQQHKPVTTSGAMAKMYASEACVKIANEAVQIHGGYGYTKDFPVEKFYRDSKLCT
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCCEEE
IGEGTTEIQKLVISRNLLKE
ECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]