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The map label for this gene is pkn1 [H]

Identifier: 146299613

GI number: 146299613

Start: 2136072

End: 2137466

Strand: Direct

Name: pkn1 [H]

Synonym: Fjoh_1853

Alternate gene names: 146299613

Gene position: 2136072-2137466 (Clockwise)

Preceding gene: 146299612

Following gene: 146299614

Centisome position: 35.04

GC content: 37.2

Gene sequence:

>1395_bases
ATGAAGAAGTTTATTGCATTTGCAGCAATGTTAACACTAGTAATCGGCTGTGGTAAGTCAGGTGACAAAGGTGAATTAGT
TGGTGTTACAGGAGGGAAATGGCATCCTGAAAAACCGTATGGAATGACTTTGGTTCCGGGTGGATCTTTTATTATGGGTA
AATCTGATGGTGACTTAGCTAATGTAGAAGATGCTCCAACAAGAACTGTAACTGTTCGCTCGTTTTATATGGACGAAACT
GAGATCACTAATAGTGAGTACCGTCAATTTGTAGAGTGGGTAAAAGATTCTACAATGAGAGTTCGTCTTGCTATTTTAGC
TGATGAAACTGGTCAAAAAAGTACTGGTGACAAAGGTAAAAAAGGCGGTAGTATTGCTGATTATGCATTTAATGATTCTG
AGCCGGATAAAATGACGGCTTATGATAAATATATGTATGATAACTACTATAGTGTAGGGACAAAAGATGATCCGTATGCT
GGTAGAAAATTAAACAAAAAAGTAAAATTAATTAGAGATACTAAAGCTTATCCAGATGAGTATTATGCTGAAGTAATGGA
TTCTATGTATTTACCAATTGAAGAATCATACAATGGTTTAAGAACAATTGATGTAAATAAATTGAAATTCCGTTATTCTT
GGATGGATATTCAGGCAGCTGCAAAAGCTAAAGTTGGAAAAAGAAAAGACTTCGTTAAAACTGAACAAGTTAATGTATAC
CCTGATACAACAGTTTGGATTAAAGATTTCGCATATTCATATAATGAGCCAATGCACAATGATTATTTCTGGCACAAAGC
TTACGGAGATTATCCAGTAGTAGGTGTGACTTGGAAACAAGCTAAAGCATTCTGTGCTTGGAGAACTTTAAATAAAAACA
GCTACATTAAATCTAAGAAAAAAGGACGTGATTTAGTTAACGCATTCAGACTTCCAACAGAAGCAGAATGGGAGTATGCT
GCAAGAGGTGGTCTGGAGTCTGCTACATACCCTTGGGGAGGTCCTTACACTAAGAGTGACAGAGGATGCTTCATGGCAAA
CTTTAAACCAAACAGAGGAGATTACGCTGCAGACGAGGCTTTATATACTGTTGAAGCAAAATCTTACGAGCAAAACGGTT
ATGGACTATATAACATGGCAGGAAACGTTTCTGAGTGGACAGATTCGGCTTACAATCCAAATGCATACGAGTATGTTTCT
ACAATGAACCCTAACGTAATTGATGGAAACAACCAAAGAAAAGTTGTTCGTGGAGGATCTTGGAAAGATGTTGCTTACTT
CCTGCAAGTAAGTACTCGTGATCACGAATATGCTGATTCTGCAAGAAGCTACATTGGTTTCAGAACTGTACAAGATTACA
TGGGAACTCAAGTAACAGGAGGCGGAAGAAAATAA

Upstream 100 bases:

>100_bases
TTTGAACGGTAAAAGAAAATTCGCAAATAGGTATTGTTTTTTAGATAAATAATAAATACGTTTACGGACTTTTAGTAATG
AATAGATAATCCAAATTTAT

Downstream 100 bases:

>100_bases
TAATAACTTAGTGTATAATTAAATCAATATACAAAAACCAAATCGAATCTATTTAAAATTAAAACCTAAAAAAGAATTAT
TATGGCATTATTAAGTAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKKFIAFAAMLTLVIGCGKSGDKGELVGVTGGKWHPEKPYGMTLVPGGSFIMGKSDGDLANVEDAPTRTVTVRSFYMDET
EITNSEYRQFVEWVKDSTMRVRLAILADETGQKSTGDKGKKGGSIADYAFNDSEPDKMTAYDKYMYDNYYSVGTKDDPYA
GRKLNKKVKLIRDTKAYPDEYYAEVMDSMYLPIEESYNGLRTIDVNKLKFRYSWMDIQAAAKAKVGKRKDFVKTEQVNVY
PDTTVWIKDFAYSYNEPMHNDYFWHKAYGDYPVVGVTWKQAKAFCAWRTLNKNSYIKSKKKGRDLVNAFRLPTEAEWEYA
ARGGLESATYPWGGPYTKSDRGCFMANFKPNRGDYAADEALYTVEAKSYEQNGYGLYNMAGNVSEWTDSAYNPNAYEYVS
TMNPNVIDGNNQRKVVRGGSWKDVAYFLQVSTRDHEYADSARSYIGFRTVQDYMGTQVTGGGRK

Sequences:

>Translated_464_residues
MKKFIAFAAMLTLVIGCGKSGDKGELVGVTGGKWHPEKPYGMTLVPGGSFIMGKSDGDLANVEDAPTRTVTVRSFYMDET
EITNSEYRQFVEWVKDSTMRVRLAILADETGQKSTGDKGKKGGSIADYAFNDSEPDKMTAYDKYMYDNYYSVGTKDDPYA
GRKLNKKVKLIRDTKAYPDEYYAEVMDSMYLPIEESYNGLRTIDVNKLKFRYSWMDIQAAAKAKVGKRKDFVKTEQVNVY
PDTTVWIKDFAYSYNEPMHNDYFWHKAYGDYPVVGVTWKQAKAFCAWRTLNKNSYIKSKKKGRDLVNAFRLPTEAEWEYA
ARGGLESATYPWGGPYTKSDRGCFMANFKPNRGDYAADEALYTVEAKSYEQNGYGLYNMAGNVSEWTDSAYNPNAYEYVS
TMNPNVIDGNNQRKVVRGGSWKDVAYFLQVSTRDHEYADSARSYIGFRTVQDYMGTQVTGGGRK
>Mature_464_residues
MKKFIAFAAMLTLVIGCGKSGDKGELVGVTGGKWHPEKPYGMTLVPGGSFIMGKSDGDLANVEDAPTRTVTVRSFYMDET
EITNSEYRQFVEWVKDSTMRVRLAILADETGQKSTGDKGKKGGSIADYAFNDSEPDKMTAYDKYMYDNYYSVGTKDDPYA
GRKLNKKVKLIRDTKAYPDEYYAEVMDSMYLPIEESYNGLRTIDVNKLKFRYSWMDIQAAAKAKVGKRKDFVKTEQVNVY
PDTTVWIKDFAYSYNEPMHNDYFWHKAYGDYPVVGVTWKQAKAFCAWRTLNKNSYIKSKKKGRDLVNAFRLPTEAEWEYA
ARGGLESATYPWGGPYTKSDRGCFMANFKPNRGDYAADEALYTVEAKSYEQNGYGLYNMAGNVSEWTDSAYNPNAYEYVS
TMNPNVIDGNNQRKVVRGGSWKDVAYFLQVSTRDHEYADSARSYIGFRTVQDYMGTQVTGGGRK

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=189, Percent_Identity=33.8624338624339, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI194248088, Length=205, Percent_Identity=32.6829268292683, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI226437577, Length=189, Percent_Identity=33.8624338624339, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI38202250, Length=195, Percent_Identity=32.3076923076923, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI257470975, Length=195, Percent_Identity=32.3076923076923, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI257470977, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI20130397, Length=190, Percent_Identity=32.6315789473684, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 52668; Mature: 52668

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFIAFAAMLTLVIGCGKSGDKGELVGVTGGKWHPEKPYGMTLVPGGSFIMGKSDGDLA
CCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCCC
NVEDAPTRTVTVRSFYMDETEITNSEYRQFVEWVKDSTMRVRLAILADETGQKSTGDKGK
CCCCCCCEEEEEEEEECCCHHCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCC
KGGSIADYAFNDSEPDKMTAYDKYMYDNYYSVGTKDDPYAGRKLNKKVKLIRDTKAYPDE
CCCCEEEECCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHCCCEEEEECCCCCCHH
YYAEVMDSMYLPIEESYNGLRTIDVNKLKFRYSWMDIQAAAKAKVGKRKDFVKTEQVNVY
HHHHHHHHHCCCHHHCCCCEEEEEECEEEEEEEEEEHHHHHHHHCCCCCCCEECCEEEEC
PDTTVWIKDFAYSYNEPMHNDYFWHKAYGDYPVVGVTWKQAKAFCAWRTLNKNSYIKSKK
CCCEEEEEHHHHHCCCCCCCCCEEEECCCCCCEEEEEHHHHHEEEEEEECCCCCCHHHHH
KGRDLVNAFRLPTEAEWEYAARGGLESATYPWGGPYTKSDRGCFMANFKPNRGDYAADEA
HHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCE
LYTVEAKSYEQNGYGLYNMAGNVSEWTDSAYNPNAYEYVSTMNPNVIDGNNQRKVVRGGS
EEEEEECCCCCCCCEEEECCCCHHHHCCCCCCCCHHHHEECCCCCEECCCCCEEEEECCC
WKDVAYFLQVSTRDHEYADSARSYIGFRTVQDYMGTQVTGGGRK
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKFIAFAAMLTLVIGCGKSGDKGELVGVTGGKWHPEKPYGMTLVPGGSFIMGKSDGDLA
CCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCCC
NVEDAPTRTVTVRSFYMDETEITNSEYRQFVEWVKDSTMRVRLAILADETGQKSTGDKGK
CCCCCCCEEEEEEEEECCCHHCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCC
KGGSIADYAFNDSEPDKMTAYDKYMYDNYYSVGTKDDPYAGRKLNKKVKLIRDTKAYPDE
CCCCEEEECCCCCCCCHHHHHHHHHHCCEEECCCCCCCCCCCHHCCCEEEEECCCCCCHH
YYAEVMDSMYLPIEESYNGLRTIDVNKLKFRYSWMDIQAAAKAKVGKRKDFVKTEQVNVY
HHHHHHHHHCCCHHHCCCCEEEEEECEEEEEEEEEEHHHHHHHHCCCCCCCEECCEEEEC
PDTTVWIKDFAYSYNEPMHNDYFWHKAYGDYPVVGVTWKQAKAFCAWRTLNKNSYIKSKK
CCCEEEEEHHHHHCCCCCCCCCEEEECCCCCCEEEEEHHHHHEEEEEEECCCCCCHHHHH
KGRDLVNAFRLPTEAEWEYAARGGLESATYPWGGPYTKSDRGCFMANFKPNRGDYAADEA
HHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCE
LYTVEAKSYEQNGYGLYNMAGNVSEWTDSAYNPNAYEYVSTMNPNVIDGNNQRKVVRGGS
EEEEEECCCCCCCCEEEECCCCHHHHCCCCCCCCHHHHEECCCCCEECCCCCEEEEECCC
WKDVAYFLQVSTRDHEYADSARSYIGFRTVQDYMGTQVTGGGRK
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]